Clinical trials: Hypertensive Disorders
Cardiovascular Diseases, Hypercholesterolemia
Vascular Lifestyle-Intervention and Screening in Pharmacy
The overall goal of the present project is to contribute to new knowledge about the effect of a low threshold population screening system for cardiovascular risk factors in Norway.
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Dyslipidemia, Hypertensive Disease
- Trial name
- VISA (NCT02223793)
- Testing
- Information on high risk factor levels and lifestyle advice, No information on high risk factor levels but lifestyle advice, No information on high risk factor levels, nor lifestyle advice
- Where
- Norway
- Volunteers
- 582 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Posterior Reversible Encephalopathy Syndrome
Prognostic Observation of Posterior Reversible Encephalopathy Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) is a clinical-radiological entity, which is associated with a variety of clinical conditions.
- Trial name
- POPRES (NCT02665598)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yantai Yuhuangding Hospital
Essential Hypertension
The Prevalence of Sympathetic Overactivity in Primary Hypertensive Patients.
The purpose of this NIS is to assess the prevalence of sympathetic overactivity in patients with newly diagnosed essential hypertension.
- Trial name
- SORT (NCT01295021)
- Where
- 97 sites in India
- Volunteers
- 1,514 people
- Sponsor
- AstraZeneca
Diabetes, Hypertension
Renal and Hormonal Effects of Pioglitazone
This study examines the effects of pioglitazone on renal sodium handling in subjects prone to insulin resistance, i.e. diabetic and/or hypertensive subjects.
- Trial name
- NCT01090752
- Testing
- Pioglitazone, Metformin
- Where
- Switzerland
- Volunteers
- 16 people
- Sponsor
- University Hospital, Geneva
Autonomic Dysfunction
Cardiac Autonomic Modulation in Older Hypertensive Individuals Submitted to Different Types of Physical Training
Sixty-one sedentary older hypertensive individuals were randomized to four groups: continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), and control (C) group.
- Trial name
- NCT05135247
- Testing
- Exercise
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Chronic Kidney Diseases, Hypertension
Tunisian Clinical Registry on Chronic Kidney Disease in Hypertensive Patients
In Tunisia, high blood pressure (HTN) is a public health problem whose prevalence varies from 28.7% to 34.7%. Hypertension can be both, cause and consequence of chronic kidney disease, and its prevalence is quite high in this…
- Trial name
- TUN-CKDH (NCT05991089)
- Where
- Tunisia
- Volunteers
- 11,770 people
- Sponsor
- Dacima Consulting
Essential Hypertension
Valsartan and Amlodipine Compared to Losartan and Amlodipine in Hypertensive Patients
Hypertensive patients with moderate hypertension have a risk to develop cardiovascular events of 15-20% over a period of 10 years.
- Trial name
- NCT00716950
- Testing
- valsartan/amlodpine, losartan/amlodpine
- Where
- Italy
- Volunteers
- 187 people
- Sponsor
- University of Pavia
Hypercholesterolemia, Hypertension
Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High Cholesterol
Cells in the lining of blood vessels produce various substances that cause the vessels to dilate (relax) and constrict (tighten), thereby regulating blood flow.
- Trial name
- NCT00006071
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Pre-Eclampsia, Eclampsia
Catestatin and Hypertension in Pregnancy
Catestatin is a kind of protein involved with cardiovascular disease. Accumulated evidence shows that Catestatin may be a predictor of primary hypertension, but whether it plays the same role in pregnant hypertensive disorders…
- Conditions
- Pre-Eclampsia, Eclampsia, Hypertension, Pregnancy-Induced, Hypertension in Pregnancy
- Trial name
- NCT03200743
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yuchen Pan
Hypertensive Disorders of Pregnancy
Vitamin D and Hypertensive Disorders of Pregnancy
The purpose of this study is to further investigate the association between vitamin D deficiency/insufficiency and hypertensive disorders of pregnancy by studying the impact of screening for vitamin D deficiency and…
- Trial name
- NCT07017920
- Testing
- Vitamin D Levels measurement
- Volunteers
- 594 people
- Sponsor
- TriHealth Inc.
Hypertension
Clinical Response of EXTOR (Amlodipine/Valsartan) in Newly Diagnosed Hypertensive Patients.
The American College of Cardiology/American Heart Association hypertension guidelines recommend treatment initiation with dual antihypertensive therapy in adults with stage 2 hypertension (corresponding to grade 1 and 2 in the…
- Trial name
- HELP (NCT06625346)
- Testing
- Fixed-Dose Combination of Amlodipine/Valsartan
- Where
- 2 sites in Pakistan
- Volunteers
- 420 people
- Sponsor
- The Searle Company Limited Pakistan
Hypertension
An Observational Study to Describe the Effectiveness of Angiotensin Converting Enzyme Inhibitor and Calcium Channel Blocker Combination in the Management of Hypertensive Patients With Elevated Heart Rate and Type 2 Diabetes
To describe the effectiveness of angiotensin-converting enzyme inhibitor and non-dihydropyridine calcium channel blocker single pill combination on systolic blood pressure (SBP) lowering in hypertensive patients with elevated…
- Trial name
- HARVEST-TR (NCT02298556)
- Where
- 23 sites in Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Abbott
Reproductive Health, Gestatiaonl Diabetes Mellitus
Exploring Reproductive Health Among Women in Somaliland
Somaliland faces persistently high burdens of maternal and perinatal mortality, with limited population-based data on pregnancy complications, sociocultural influence on maternal health, and women's reproductive health needs…
- Conditions
- Reproductive Health, Gestatiaonl Diabetes Mellitus, Hypertensive Disorders of Pregnancy, Contraception
- Trial name
- PROMISE (NCT07438379)
- Where
- Somalia
- Volunteers
- 808 people
- Sponsor
- University of Hargeisa
Hypertension, Autonomic Dysfunction
Autonomic Regulation of Blood Pressure and Heart Rate During Orthostasis and Exercise in Healthy and Hypertensive Individuals
The goal of this observational study is to assess arterial stiffness and autonomic regulation of blood pressure and heart rate in healthy adults and people with arterial hypertension during orthostatic stress and graded physical…
- Conditions
- Hypertension, Autonomic Dysfunction, Orthostatic Hypotension
- Trial name
- NCT07482462
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Open-Angle Glaucoma, Ocular Hypertension
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70
To compare intraocular pressure lowering effectiveness of a combination drug vs. two individual drugs dosed alone.
- Trial name
- NCT00047541
- Testing
- Alcon Investigational Agent
- Where
- United States
- Sponsor
- Alcon Research
Hypertension, Prehypertension
Effects and Safety of Menthol on Blood Pressure and Metabolic Parameters in Prehypertensive and Mild Hypertensive Patients
Prehypertension and mild hypertension are associated with an increased risk of atherosclerosis and coronary artery disease, and often complicated with the metabolic disorder of glucose and lipid.
- Trial name
- ESMAB (NCT01408446)
- Testing
- Menthol
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zhiming Zhu
Uncontrolled Hypertension, Autosomal Dominant Polycystic Kidney Disease
Renal Denervation in ADPKD- RDN-ADPKD Study
RDN-ADPKD is a prospective, randomized (1:1, central randomization), single-center, hypothesis-generating, feasibility study. The purpose of the RDN-ADPKD study is to demonstrate efficacy and document safety of renal denervation…
- Conditions
- Uncontrolled Hypertension, Autosomal Dominant Polycystic Kidney Disease, Renal Denervation
- Trial name
- RDN-ADPKD (NCT05460169)
- Testing
- Renal denervation
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension
Clinical Study to Evaluate the Antihypertensive Efficacy and Changes of Neurohormonal Markers of Fimasartan and Atenolol With Exaggerated Blood Pressure Response During Exercise in Essential Hypertensive Patients
The purpose of this study is to evaluate the antihypertensive efficacy and changes of neurohormonal markers of fimasartan and atenolol with exaggerated blood pressure response during exercise in essential hypertensive patients.
- Trial name
- NCT01736488
- Testing
- Fimasartan, Atenolol
- Where
- 4 sites in South Korea
- Volunteers
- 25 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension
Telmisartan, Amlodipine and Flow Mediated Dilation
To show superior effects of the combination Telmisartan and Amlodipine (T and A) vs Olmesartan and Hydrochlorothiazide (O and HCTZ) on endothelial dysfunction as measured by flow mediated dilation (FMD) in hypertensive at risk…
- Trial name
- TEAMSTAprotect (NCT01180205)
- Testing
- Telmisartan, Amlodipine, Olmesartan medoxomil
- Where
- Germany
- Volunteers
- 576 people
- Sponsor
- Johannes Gutenberg University Mainz
Hypertension, Lipid Metabolism Disorders
Alpha-linolenic Acid and Blood Pressure
Rationale: Increased intakes of n-3 long chain polyunsaturated fatty acids eicosapentanoic acid (EPA) and docosahexaenoic acid (DHA), mainly found in fatty fish, are recommended for the prevention of coronary heart disease.
- Trial name
- VASALA (NCT02243969)
- Testing
- Flaxseed oil, high oleic sunflower oil (HOSF)
- Where
- Netherlands
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
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