Clinical trials: Hypertensive Hemorrhage, Intracranial
Cerebral Hemorrhage, Intracranial Arteriovenous Malformations
MRI for the Early Evaluation of Acute Intracerebral Hemorrhage
What happens in the borderzone of a cerebral hemorrhage remains widely onknown and furhter the best timing for doing MR to look for vascular pathology in cerebral hemorrhage has not yet been determined.
- Conditions
- Cerebral Hemorrhage, Intracranial Arteriovenous Malformations, Intracranial Hemorrhage, Hypertensive, Brain Neoplasms
- Trial name
- NCT01689402
- Testing
- MRI Scan with the specified sequences below:
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Bispebjerg Hospital
Intracerebral Hemorrhage, CAA - Cerebral Amyloid Angiopathy
MRI-markers to Monitor Small Vessel Disease Dynamics in the Prognosis of Small Vessel Disease-associated, Cerebrovascular Events
This is a nested cohort study in the PRO-SVD cohort. Small vessel disease is a chronic disease and is thought to progress over time.
- Conditions
- Intracerebral Hemorrhage, CAA - Cerebral Amyloid Angiopathy, Cerebral Small Vessel Diseases
- Trial name
- MRI-PRO-SVD (NCT05773235)
- Testing
- Combined 3- and 7 Tesla-MRI
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Basal Ganglia Hemorrhage
Minimally Invasive Treatment of Hypertensive Basal Ganglia Hemorrhage by Transfrontal Keyhole Neuroendoscopy
To compare the prognosis of patients with hypertensive intracerebral hemorrhage treated by two different surgical methods, and to clarify the therapeutic effect of minimally invasive surgery, so as to find a better surgical…
- Trial name
- NCT04958525
- Testing
- Keyhole neuroendoscopic transfrontal ultrasound-guided hematoma removal, Small bone window craniotomy for hematoma removal under microscope
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Peking University Third Hospital
Intracerebral Hemorrhage
Prevention of Hypertensive Injury to the Brain by Intensive Treatment of Blood Pressure After Intracerebral Haemorrhage (PROHIBIT-ICH)
PROHIBIT-ICH will randomise participants (target=112) to compare a strategy of intensive blood pressure (BP) treatment (target <120/80 mm Hg) guided by remote telemetric home BP monitoring, versus standard primary care, in adult…
- Trial name
- PROHIBIT-ICH (NCT03863665)
- Testing
- A&D BP Digital Blood Pressure Monitor (UA-767PBT-Ci) CE Declaration UA-767PBT-Ci
- Where
- 16 sites in United Kingdom
- Volunteers
- 86 people
- Sponsor
- University College, London
Basal Ganglionic Hemorrhage
Prognostic Factors for Surgical Management of Large Hypertensive Basal Ganglionic Haemorrhage
The aim of this study is to present current and comprehensive recommendations for surgical treatment of this hematoma and to determine the factors that may improve the survival rate
- Trial name
- NCT06309940
- Testing
- Prognostic factors of surgical evacuation of basal ganglionic haemorrhage
- Volunteers
- 25 people
- Sponsor
- Assiut University
Intracerebral Hemorrhage, Cerebral Edema
Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage
The purpose of this study is to test the safety and effectiveness of a single dose of fingolimod in patients with primary spontaneous intracerebral hemorrhage (ICH).
- Conditions
- Intracerebral Hemorrhage, Cerebral Edema, Stroke Hemorrhagic, Intracerebral Hemorrhage, Hypertensive
- Trial name
- FITCH (NCT04088630)
- Testing
- Fingolimod, Open-label Fingolimod
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage
Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral Hemorrhage
The overall aim of this pilot study is to investigate the development of magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) markers after cerebral amyloid angiopathy (CAA)-related and hypertensive arteriopathy…
- Conditions
- Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage, Hypertensive Hemorrhage, Intracranial, Cognitive Decline
- Trial name
- COACH (NCT05499169)
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Leiden University Medical Center
Hypertensive Intracerebral Hemorrhage
Acute Hypertensive Cerebral Hemmorrhage Surgery
The Neuroendoscopic, Trans-occipital Approach Evacuation of Acute Hypertensive Cerebral Hemmorrhage Combined Low-drainage Surgery: a Multi-center Clinical Trial
- Trial name
- NET-OCEAN (NCT04957849)
- Testing
- The Neuroendoscopic, Trans-occipital Approach Evacuation of Acute Hypertensive Cerebral Hemmorrhage Combined Low-drainage Surgery, Endoscopic Evacuation of Acute Hypertensive Intracerebral Hemorrhage via Trans-frontal keyhole approach
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Shanghai Changzheng Hospital
Intracranial Aneurysm
Aneurysmal Subarachnoid Hemorrhage and Superior Mesenteric Artery Flow Study
The purpose of this research study is to determine if the diameter and flow of the superior mesenteric artery in patients with aneurysmal subarachnoid hemorrhage undergoing hypertensive therapy for cerebral artery vasospasm are…
- Trial name
- NCT02684500
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Intracerebral Hemorrhage
Antihypertensive Treatment of Acute Cerebral Hemorrhage-II
The specific aims of this study are to: 1. Definitively determine the therapeutic benefit of the intensive treatment relative to the standard treatment in the proportion of patients with death and disability (mRS 4-6) at 3 months…
- Trial name
- ATACH-II (NCT01176565)
- Testing
- Intravenous nicardipine hydrochloride
- Where
- 171 sites in United States, Canada and 5 more
- Volunteers
- 1,000 people
- Sponsor
- University of Minnesota
Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive
Start or STop Anticoagulants Randomised Trial (SoSTART)
Primary research question: For adults surviving spontaneous (non-traumatic) symptomatic intracranial haemorrhage with persistent/paroxysmal atrial fibrillation/flutter (AF), does starting full treatment dose oral anticoagulation…
- Conditions
- Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive, Subarachnoid Hemorrhage, Subdural Hematoma
- Trial name
- SoSTART (NCT03153150)
- Testing
- Apixaban, Rivaroxaban, Edoxaban
- Where
- 67 sites in United Kingdom
- Volunteers
- 203 people
- Sponsor
- University of Edinburgh
Intracranial Hemorrhage, Hypertensive
Yiqi Huayu Jiedu Therapy for Non-Surgical Supratentorial Hypertensive Intracerebral Hemorrhage
This multicenter, prospective, double-blind, randomized controlled trial will enroll 902 non-surgical patients with supratentorial hypertensive intracerebral hemorrhage who meet the traditional Chinese medicine syndrome criteria…
- Trial name
- CHAIN2 (NCT07580235)
- Testing
- Yiqi Huayu Jiedu Mixture Intervention
- Volunteers
- 902 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Intracerebral Hemorrhage, Hypertensive, Traditional Chinese Medicine
Clinical Evaluation of Removing Blood Stasis Therapy in Treating Acute Cerebral Hemorrhage Safety and Efficacy
The purpose of this research is to use the "Removing Blood Stasis Decotion" of traditional Chinese medicine treating the acute stage of cerebral hemorrhage with stroke associated pneumonia to explore the impact of "Removing Blood…
- Trial name
- CERBSTTSCH (NCT03354026)
- Testing
- AICH-PXZY, AICH-without PXZY
- Where
- 2 sites in China
- Volunteers
- 306 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Hypertensive Intracerebral Hemorrhage
Robotic Assisted Evacuation of Subacute and Chronic Supratentorial Deep Hypertensive Intracerebral Hemorrhage
Robotic Assisted Evacuation of Subacute and Chronic Supratentorial Deep Hypertensive Intracerebral Hemorrhage for Accelerating Functional Rehabilitation (RESCUE-CHAIN): a Multi-center Randomized Controlled Trial
- Trial name
- NCT04957862
- Testing
- Robotic Assisted Evacuation
- Volunteers
- 428 people
- Sponsor
- Shanghai Changzheng Hospital
Severe Traumatic Brain Injury, Intracranial Hypertension
Ketamine for Sedation in Severe Traumatic Brain Injury
This protocol is for an open-label randomized trial evaluating the safety of using ketamine in combination with propofol for sedation versus the standard of care analgosedation in patients admitted to the intensive care unit with…
- Conditions
- Severe Traumatic Brain Injury, Intracranial Hypertension, Intracranial Hemorrhage, Hypertensive
- Trial name
- Ketamine (NCT06429657)
- Testing
- Ketamine with propofol, Standard of Care propofol, fentanyl, dexmedetomidine, morphine, hydromorphone, midazolam, or lorazepam
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Intracranial Hemorrhage, Hypertensive
Intravenous Immunoglobulin for Acute Intracranial Hemorrhage
This pilot study aims to investigate whether intravenous immunoglobulin is safe and effective in alleviating perihematomal edema and neurologic deficits in patients with intracranial hemorrhage.
- Trial name
- NCT02782897
- Testing
- Immunoglobulin Therapy, Standard management
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wei Wang
Intracranial Hemorrhage, Hypertensive
Neurological Outcomes of Primary Intracerebral Haemorrhage
The main objective of this study is to determine the one-year neurological outcome of patients admitted to an intensive care unit (ICU) for a primary and spontaneous supratentorial intracerebral hemorrhages (ICH).
- Trial name
- HIP-REA (NCT03995940)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Hypertensive Intracerebral Hemorrhage
Stereotactic Aspiration and Thrombolysis of Intracerebral Hemorrhage: a Prospective Controlled Study
The purpose of this study is to evaluate the superiority of effect of the modified micro-invasive aspiration and drainage and conservative medical therapy in the treatment of ICH spontaneously hypertensive scientifically.
- Trial name
- SATIH (NCT00752024)
- Testing
- YL-1 type of intracranial hematoma puncture needle, dehydrating agent, haemostatic
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Huazhong University of Science and Technology
Hypertensive Intracerebral Hemorrhage
Dose-effect Relationship of Rt-PA on ICH Evacuation
The purpose of this trial is to determine the optimal dose of rt-PA in the treatment of intracerebral hemorrhage (ICH) using a combination of minimally invasive surgery and clot lysis with rt-PA。
- Trial name
- NCT02472574
- Testing
- YL-1 type of intracranial hematoma puncture needle, rt-PA
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Tongji Hospital
Hypertensive Intracerebral Hemorrhage, Intraventricular Hemorrhage
Neuroinflammatory Response in Patients With ICH and IVH Treated With rtPA
This study compares the neuroinflammatory response in patients with hypertensive ICH associated with IVH treated with intraventriculary applied rtPA, and the control group.
- Conditions
- Hypertensive Intracerebral Hemorrhage, Intraventricular Hemorrhage, Brain Injuries
- Trial name
- NCT03452722
- Testing
- intraventricual recombinant tissue plasminogen activator application
- Volunteers
- 88 people
- Sponsor
- University of Rijeka