Clinical trials: Hypertensive Patients
Hypertension, Obesity
Pleiotropic Effects of Azilsartan Medoxomil Over Insulin Resistance in Obese, Diabetic and Hypertensive Patients
The goal of this study is to build a mathematical model to explain the effect of two doses of azilsartan (40 and 80 mg) upon metabolic (insulin resistance, glucose) and inflammatory parameters (cytokines) in function of…
- Conditions
- Hypertension, Obesity, Type 2 Diabetes Mellitus
- Trial name
- NCT02235519
- Testing
- Azilsartan 40 mg., Azilsartan 80 mg
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospital General de México Dr. Eduardo Liceaga
Hypertensive Episode
Prevalence of Hypertensive Disease in Patients Presenting for Elective Surgery in the Western Cape, South Africa
Hypertension is a major medical and public health burden throughout the world. It is estimated that 1 in 3 adult South Africans are diagnosed with hypertension, however detailed statistics reflecting the burden of disease are…
- Trial name
- HASS (NCT03157661)
- Where
- 7 sites in South Africa
- Volunteers
- 382 people
- Sponsor
- University of Cape Town
Hypertension
An Observational Study to Evaluate the Efficacy of Lodoz in a Population of Hypertensive Patients
This is an observational, prospective, non-interventional, non-randomised, open label multicentric study planned to be conducted in 1000 subjects with mild to moderate primary hypertension in approximately 20 centres in Thailand.
- Trial name
- Lodoz OS (NCT01080742)
- Testing
- Lodoz (Combination of bisoprolol and hydrochlorothiazide)
- Where
- Thailand
- Volunteers
- 1,007 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Sacubitril/Valsartan, Hypertension
Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study
The purpose of this study is to investigate the effect of sacubitril/valsartan on cardiac function assessed by cardiac magnetic resonance (CMR) in hypertensive patients stratified by BMI.
- Conditions
- Sacubitril/Valsartan, Hypertension, Obesity
- Trial name
- NCT05498675
- Testing
- Sacubitril / Valsartan Oral Tablet [Entresto], ACEI/ARB
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Friendship Hospital
Hypertension
Effect of LCZ696 on Urinary Microalbumin and Pulse Wave Velocity in Perimenopausal Patients With Hypertension
To explore the efficacy of Sacubitril/Valsartan in the treatment of perimenopausal hypertensive patients, as well as the difference between the antihypertensive efficacy and valsartan, the therapeutic effect of its exposure to…
- Trial name
- NCT04800081
- Testing
- Sacubitril/Valsartan, Valsartan
- Where
- China
- Volunteers
- 264 people
- Sponsor
- LanZhou University
Hypertension
Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure
Randomized, double-blind, parallel group, multicenter study of subjects with Stage 1 or 2 essential hypertension who are not at target blood pressure (<140/90mmHg) at Baseline.
- Trial name
- NCT00624065
- Testing
- carvedilol controlled release/lisinopril
- Where
- 76 sites in United States
- Volunteers
- 348 people
- Sponsor
- GlaxoSmithKline
Hypertension
Efficacy and Safety of Valsartan, Hydrochlorothiazide and Amlodipine Combination Therapy in Hypertension
This study is designed to evaluate the efficacy and safety of the combination valsartan with hydrochlorothiazide and amlodipine in hypertensive patients previously treated with valsartan with hydrochlorothiazide and remaining…
- Trial name
- NCT00400777
- Testing
- Valsartan, hydrochlorothiazide and amlodipine
- Where
- Brazil
- Volunteers
- 460 people
- Sponsor
- Novartis
Prehypertension, Hypertension, Stage I
Effect of Ginseol Kg1 on Blood Pressure Lowering
In this study, we investigate the effects of Ginseol Kg1 (Korea red ginseng extract) on blood pressure in prehypertensive or stage I hypertensive patients.
- Trial name
- NCT01483430
- Testing
- Ginseol Kg1 (low dose), Ginseol Kg1(high dose)
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Hypertension
A Study to Evaluate the Combination of Valsartan + Amlodipine in Hypertensive Patients
The purpose of this study is to evaluate the efficacy of valsartan plus amlodipine in hypertensive patients not responding to treatment with amlodipine or felodipine alone.
- Trial name
- NCT00392262
- Testing
- valsartan + amlodipine
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 224 people
- Sponsor
- Novartis
Hypertension
Effectiveness and Tolerability of Tarka® in the Treatment of Hypertensive Patients With High Risk of Developing Diabetes Mellitus
The aim of this post-marketing observational study (PMOS) is to provide data on the effectiveness and tolerability of Tarka in patients with a high risk of developing diabetes mellitus, as prescribed by the physicians in a…
- Trial name
- TARDIA (NCT01079195)
- Where
- 898 sites in Bulgaria, Czechia and 5 more
- Volunteers
- 15,436 people
- Sponsor
- Abbott
Hypertensive Patients With Retinal Vein Occlusion
Diameters and Wall-to-lumen Ratio of Retinal Arterioles in Patients With Retinal Vein Occlusion.
to evaluate the wall-to-lumen ratio (WLR) of retinal arterioles in hypertensive patients with retinal vein occlusion (RVO) before and after dexamethasone intravitreal implant 0.7 mg (DEX) compared to a matched control group of…
- Trial name
- NCT01789437
- Testing
- Dexamethasone Intravitreal Implant (Ozuredex)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Università degli Studi di Brescia
Hypertensive Urgency
Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate
Hypertensive urgency (HT urgency) is an alarm sign of uncontrolled hypertension. It can be aggravated by nonadherent to medication and psychosocial stress.
- Trial name
- NCT04572672
- Testing
- Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting
- Where
- Thailand
- Volunteers
- 112 people
- Sponsor
- Khon Kaen University
Hypertension in Pregnancy, Preeclampsia
Response to Anti-hypertensives in Pregnant and Postpartum Patients
In this study, the investigators will evaluate the blood pressure response to nifedipine and labetalol in pregnant and postpartum patients, who present with hypertensive disease in pregnancy with severe range blood pressure…
- Trial name
- NCT03506724
- Testing
- Nifedipine, Labetalol
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hypertension
Canadian Study of Trandolapril on Blood Pressure in Hypertensive Patients (TRAIL)
The TRAIL study was conducted to examine the effects of escalating doses of an ACE inhibitor, trandolapril, on lowering blood pressure in Stage 1-2 hypertensive patients.
- Trial name
- TRAIL (NCT00233532)
- Testing
- Trandolapril
- Volunteers
- 2,000 people
- Sponsor
- Abbott
Hypertension
52-104 Week Off-therapy Second Extension to Study CSPP100A2365
52-104 week off-therapy second extension to study CSPP100A2365 to assess growth and development in pediatric hypertensive patients previously treated with aliskiren in studies SPP100A2365 and SPP100A2365E1
- Trial name
- NCT01420068
- Testing
- SPP100
- Where
- 25 sites in United States, Guatemala and 5 more
- Volunteers
- 106 people
- Sponsor
- LXO Group
Hypertension, Arteriosclerosis
The Effects of Lowering Dialysate Sodium in Hypertensive Hemodialysis Patients
Unfavorably high sodium intakes remain prevalent around the world. A negative sodium gradient in hemodialysis treatment results in absolute sodium removal via diffusive transport of sodium from the blood to the dialysate, and it…
- Conditions
- Hypertension, Arteriosclerosis, Left Ventricular Hypertrophy
- Trial name
- NCT01455974
- Testing
- Decreasing dialysate sodium from 138 mmol/L to 136 mmol/L
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Capital Medical University
Intracranial Hemorrhage, Hypertensive
Intravenous Immunoglobulin for Acute Intracranial Hemorrhage
This pilot study aims to investigate whether intravenous immunoglobulin is safe and effective in alleviating perihematomal edema and neurologic deficits in patients with intracranial hemorrhage.
- Trial name
- NCT02782897
- Testing
- Immunoglobulin Therapy, Standard management
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wei Wang
Hypertension
Photobiomodulation Effects on Blood Pressure and Vascular Function in Treated Hypertensive Patients
This double-blind, randomized, sham-controlled clinical trial aims to evaluate the effects of vascular photobiomodulation on blood pressure and vascular function in hypertensive patients treated with losartan.
- Trial name
- NCT07525310
- Testing
- Vascular Photobiomodulation
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Nove de Julho
Hypertension
The Effect of Chronic Care Model Based Education on Disease Management in Hypertensive Patients
Background: This study was conducted to examine the effect of planned educational intervention based on The Chronic Care Model (CCM) on the management of hypertension in patients with hypertension.
- Trial name
- CCM (NCT04411355)
- Testing
- control by dietitian, Exercise programs, control by psychiatrist
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ege University
Hypertension
Nicotinamide Mononucleotide in Hypertensive Patients
Cardiovascular and cerebrovascular diseases are most terrible killers endangering the health of Chinese residents, and hypertension is the most important risk factor.
- Trial name
- NCT04903210
- Testing
- Nicotinamide mononucleotide supplied as 400mg capsule, Lifestyle modification
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University