Clinical trials: Hypertensive Patients
Hypertension
I SAVE - Irbesartan in Mild to Moderate Hypertensive Patients
To evaluate control rate of Blood Pressure ≤ 140/90 mm Hg in non-diabetic patients, and ≤ 130/80 mm Hg in diabetic patients. To determine percentage of patients achieving blood pressure control according to their profile (naïve…
- Trial name
- NCT00335673
- Testing
- Irbesartan (Aprovel)
- Where
- Egypt
- Volunteers
- 1,630 people
- Sponsor
- Sanofi
Hypertension
A Study to Compare COREG CR to COREG CR Fixed-dose Combination in Patients With High Blood Pressure
Carvedilol controlled release is a marketed drug to treat high blood pressure. This study is to compare carvedilol controlled release to carvedilol controlled release plus lisinopril (fixed-dose combination) after repeat dosing…
- Trial name
- NCT00537043
- Testing
- SK&F-105517 (COREG CR FDC)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- GlaxoSmithKline
Diastolic Heart Failure
Impacts of Aldosterone Blockade on Myocardial Remodeling in Hypertensive Patients With Diastolic Failing Heart
Aim of study: The effects of aldosterone blockade on myocardial remodeling in hypertensive patients with diastolic failing heart remains unclarified.
- Trial name
- NCT01944384
- Testing
- aldactone
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Hypertension
Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan
This study will assess the efficacy and safety of LCZ696 in comparison to olmesartan in essential hypertensive patients not adequately responsive to olmesartan
- Trial name
- NCT01876368
- Testing
- LCZ696, Olmesartan
- Where
- 51 sites in United States, Argentina and 5 more
- Volunteers
- 376 people
- Sponsor
- Novartis Pharmaceuticals
Hypertension, Sleep Disorder
Phenotypisation of Sleep Pattern in Hypertensive Patients With Non Dipper Pattern
High blood pressure is the most common modifiable risk factor for cardiovascular diseases (CV). The large interindividual variability in clinical expression of the disease and response to treatment, however, makes the management…
- Trial name
- INTO-DIP (NCT06302738)
- Testing
- polysomnography
- Where
- 11 sites in Italy
- Volunteers
- 143 people
- Sponsor
- Istituto Auxologico Italiano
Hypertension, Obstructive Sleep Apnea
Prospective National Multi-center Registry of Obstructive Sleep Apnea Syndrome in Hypertensive Patients in China
Study name: Screening, Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome in Hypertensive Patients in China: A Prospective National Multi-center Registry.
- Trial name
- NCT05735444
- Testing
- Continuous positive airway pressure
- Where
- China
- Volunteers
- 633 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hypertension
Implementing Evidence Based Treatment of Hypertension
This study examines the use of patient initiated discussions of blood pressure medication in the primary care setting. Additionally, this study examines different levels of patient incentive(s) to initiate discussions with…
- Trial name
- NCT00265538
- Testing
- Patient educational letter to engage provider in hypertension rx discussion, Financial incentive (Arms B and C) and health educator phone call (Arm C)
- Where
- 2 sites in United States
- Volunteers
- 834 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Surgery
Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients
Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management…
- Conditions
- Cardiovascular Diseases, Surgery, Hypotension, Hypotension on Induction
- Trial name
- PRAM-in-HYPO (NCT05960604)
- Testing
- Passive leg raising
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 660 people
- Sponsor
- Recep Tayyip Erdogan University
Hypertension,Essential
An OS to Evaluate Effectiveness and Safety of Fixed-dose Combinations of FMS/AML or FMS/AML/HCTZ
The main purpose of this observation study is to collect data on the effects and side effects for 12 weeks of the medication administration of the single-pill combinations, which are fimasartan/amlodipine or…
- Trial name
- NCT05413057
- Where
- South Korea
- Volunteers
- 20,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Hypertension, Type 2 Diabetes Mellitus
Antiproteinuric Effect of Imidapril Versus Ramipril in Type 2 Diabetic and Hypertensive Patients With Microalbuminuria
Numerous clinical and experimental data show that the elective treatment of diabetic nephropathy should be based on drugs that inhibit the renin-angiotensin system (RAS).
- Conditions
- Hypertension, Type 2 Diabetes Mellitus, Microalbuminuria
- Trial name
- NCT01230034
- Testing
- Ramipril, Imidapril
- Where
- Italy
- Volunteers
- 206 people
- Sponsor
- University of Pavia
Hypertension, Arterial Stiffness
Effect of High-intensity Interval Training Combined With DASH Diet on Arterial Stiffness in Hypertensive Patients
Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide and a major risk factor for morbidity worldwide .
- Trial name
- NCT07188272
- Testing
- DASH diet, High Intensity Interval Training
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Deraya University
Hypertension
Assessment of Anesthetic Efficacy and Hemodynamic Stability of Two LA Drugs for Hypertensive Patients
Pain control in dentistry is an important factor for reducing the fear and anxiety associated with dental procedures. For tooth extraction, it is mandatory to use resources to manage pain and discomfort such as adequate…
- Trial name
- NCT06927726
- Testing
- 4% Articaine HCL With 1:100,000 Epinephrine, 3% plain mepivacaine HCL
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Chronic Coronary Syndrome, Hypertension
Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients
Evaluation of the clinical outcomes of Benidipine initiated by physician's preference in patients with hypertension and/or angina pectoris (chronic coronary syndrome) presenting to cardiology outpatient clinics in Turkey.
- Conditions
- Chronic Coronary Syndrome, Hypertension, Angina Pectoris
- Trial name
- Benidipine-TR (NCT06808321)
- Testing
- Benidipine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people
- Sponsor
- The Society of Prevention and Awareness of Cardiovascular Diseases
Hypertension, Potassium Imbalance
Occurrence of Dyskalemia With Treatment for Hypertension
Hypertension is a major public health issue associated with significant morbidities and mortality. Fixed-dose combination (FDC) pills, combining 2 or more classes of antihypertensive medications have considerable appeal because…
- Trial name
- OK (NCT05155436)
- Testing
- Fixed Dose Combination pill of Telmisartan 40mg and Amlodipine 5 mg
- Where
- Bangladesh
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- National Heart Foundation of Bangladesh
Hypertension
IMB-Guided Health Education Intervention for Medication Adherence and Blood Pressure Control in Non-adherent Hypertensive Patients
This study will evaluate the effectiveness of an Information-Motivation-Behavioral Skills (IMB) Model-guided health literacy intervention among adults with hypertension who are non-adherent to prescribed antihypertensive…
- Trial name
- NCT07894068
- Testing
- IMB Model-Guided Health Education Intervention, Usual Care
- Where
- 8 sites in Ethiopia
- Volunteers
- 230 people
- Sponsor
- Bahir Dar University
Hypertension Emergency, End-organ Damage
Post Marketing Study to Evaluate the Two Dose Regimens of Nicardipine Injection in Hypertensive Emergency Patients
To compare the efficacy and safety of two dose adjustment regimens (i.e. weight-based and non-weight-based) for the treatment of Chinese hypertensive emergency patients.
- Trial name
- NCT01872039
- Testing
- Perdipine injection
- Where
- 5 sites in China
- Volunteers
- 163 people
- Sponsor
- Astellas Pharma China, Inc.
Hypertension, Renal Denervation
Genetic Based Analysis in Hypertensive Patients
Many attempts to identify predictors of blood pressure response after renal denervation failed to identify a meaningful determination of blood pressure response.
- Conditions
- Hypertension, Renal Denervation, Genetic Predisposition
- Trial name
- NCT04321044
- Testing
- Genetic based analysis of identifying predictors of blood pressure in patients after renal denervation
- Where
- 3 sites in Germany, United Kingdom
- Volunteers
- 300 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypertension
Effects of Nebivolol on Skeletal Muscle During Exercise in Hypertensive Patients
The purpose of this study is to determine if Nebivolol improves microvascular perfusion in skeletal muscle during exercise in hypertensive patients and whether this improvement is accompanied by reduction in vascular oxidative…
- Trial name
- NCT01501929
- Testing
- Metoprolol succinate, Nebivolol, Non-invasive measurement of Cardiac Output (CO)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypertension
A Randomised, Parallel-group, Double-blind, Double-dummy Study to Compare the Effects of Lacidipine Versus Bendrofluazide on Markers of Platelet Activation and Haemorheological Factors in Hypertensive Patients
The aim of this study is to compare the effects of lacidipine on markers of platelet activation and other rheological factors in hypertensive patients with those of bendrofluazide
- Trial name
- NCT02235402
- Testing
- Lacidipine, Bendrofluazide
- Volunteers
- 26 people
- Sponsor
- Boehringer Ingelheim
Hypertension
Effects of Acute Ingestion of Dark Chocolate on Endothelial Function in Hypertensive Patients
We aimed to identify clinical and vascular parameters of treated hypertensive patients who present beneficial effects of dark chocolate for one-week period on vascular function.
- Trial name
- NCT01314924
- Testing
- Dark chocolate
- Where
- Brazil
- Volunteers
- 21 people
- Sponsor
- Hospital Universitario Pedro Ernesto