Clinical trials: Hypertensive Patients
Atrial Fibrillation
Nifedipine vs Telmisartan on Prevention of Atrial Fibrillation (AF) Recurrence in Hypertensive Patients With AF
Different lowing blood pressure strategies have a different clinical efficacies. Blocking the angiotensin II type 1 receptor (Telmisartan) reduces the incidence of episodes of atrial fibrillation in hypertensive patients with…
- Trial name
- NCT01435161
- Testing
- Nifedipine,, Telmisartan
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Hypertension, Metabolic Syndrome
Hypertension And Surgery Study: Evaluating the Implementation of a Hypertension Guideline Protocol
HASS-2 is a multi-center, cross-sectional quality improvement project: evaluating the implementation of a hypertension guideline protocol by perioperative clinicians, as a model for improving various aspects of public health.
- Conditions
- Hypertension, Metabolic Syndrome, Non-Compliance, Medication
- Trial name
- HASS-2 (NCT03921086)
- Testing
- Antihypertensive medication according to the study's algorithm
- Where
- 7 sites in South Africa
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Elective Surgical Patient, Hypertensive Patients
Effect of Dexmedetomidine on Hemodynamic Response to Endotracheal Intubation in Hypertensive Patients
Dexmedetomidine, an alpha-2 adrenergic agonist, has been shown to provide several benefits during endotracheal intubation: 1. _Reduced anxiety and stress_: Dexmedetomidine's anxiolytic and sedative effects help reduce anxiety and…
- Conditions
- Elective Surgical Patient, Hypertensive Patients, Blood Pressure, Hypertensive Elderly Patients
- Trial name
- NCT06712186
- Testing
- Dexmedetomidine Group / Group D
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Hypertension Self-management, Hypertension
Adaptive Intervention Model for Hypertension Self-Management in Rural Areas: A Doctor-Patient Interaction Approach
The aim of this project is to develop and validate an adaptive intervention model to improve self-management behavior in rural hypertensive patients.
- Trial name
- NCT06869031
- Testing
- Standard Interactive Intervention for Hypertension Management, Intensified Interactive Intervention for Hypertension Management
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Yuju Wu
Hypertension, Chronic Kidney Disease
Effects of Low Sodium Intake on the Anti-proteinuric Efficacy in Hypertensive Patient With Olmesartan
Purpose of this study 1. Intensive education for low salt diet will be enhance the anti-proteinuric effect of Olmesartan, a popular anti-hypertensive drug of angiotensin II receptor blocker, in Koreans compared to conventional…
- Conditions
- Hypertension, Chronic Kidney Disease, Microalbuminuria
- Trial name
- ESPECIAL (NCT01552954)
- Testing
- Intensive education of low salt diet
- Where
- 7 sites in South Korea
- Volunteers
- 269 people
- Sponsor
- Seoul National University Bundang Hospital
Arterial Hypertension, Metabolic Syndrome
Blood Pressure Control and Compliance to Treatment in Hypertensive Patients With Metabolic Syndrome: a Study Based on Home Blood Pressure Telemonitoring and Assessment of Psychological Determinants
The purpose of this study is to assess whether, in patients at high cardiovascular risk (hypertension with metabolic syndrome), long-term (1-year) blood pressure control is most effective when based on home blood pressure…
- Trial name
- TELEBPMET (NCT01541566)
- Where
- 12 sites in Italy
- Volunteers
- 254 people
- Sponsor
- Italian Institute of Telemedicine
Hypertension, Physical Activity
Uncontrolled Hypertension Management Among Jordanian Adults
This study will evaluate a newly developed multimodal health intervention including dietary approach to stop hypertension (DASH) diet, exercise (Ex), and medication adherence (MA) using motivational interviewing (MI) counselling…
- Conditions
- Hypertension, Physical Activity, Dietary Habits, Medication Adherence
- Trial name
- DASH-ExMAMI (NCT06156631)
- Testing
- DASH-ExMAMI
- Where
- 4 sites in Jordan
- Volunteers
- 126 people
- Sponsor
- Universiti Sains Malaysia
Hypertension and Left Ventricular Hypertrophy (Thickening of the Main Pumping Chamber of the Heart)
Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study (0954-133)
The LIFE study was conducted from 1995-2001. This study was conducted in 9193 patients with high blood pressure and thickening of the main pumping chamber of the heart.
- Trial name
- NCT00338260
- Testing
- MK0954, /Duration of Treatment : 5 Years, Comparator : atenolol /Duration of Treatment : 5 Years
- Volunteers
- 496 people
- Sponsor
- Organon and Co
Hypertension
Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine
PRECIOUS Study aims to evaluate the efficacy and safety of therapy with fixed-dose combination (FDC) of perindopril/amlodipine (Amlessa®) and FDC of perindopril/indapamide/amlodipine (Co-Amlessa®) on blood pressure reduction in…
- Trial name
- PRECIOUS (NCT03738761)
- Testing
- Amlessa®, Co-Amlessa®
- Where
- 34 sites in Armenia, Croatia and 5 more
- Volunteers
- 471 people
- Sponsor
- KRKA
Hypertension, Hypercholesterolemia
Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High Cholesterol
The goal of this clinical trial is to test whether one pill that combines ezetimibe, rosuvastatin, and amlodipine can safely lower cholesterol and blood pressure in Korean adults with high blood pressure and high cholesterol.
- Trial name
- NCT07564726
- Testing
- Amlodipine, Ezetimibe/Rosuvastatin
- Where
- 21 sites in South Korea
- Volunteers
- 163 people
- Sponsor
- Celltrion Pharm, Inc.
Hypertension
Safety and Efficacy of Valsartan Plus Hydrochlorothiazide and Amlodipine in Hypertensive Patients
A double-blind, active-controlled, randomized trial to compare Valsartan plus Hydrochlorothiazide 80mg/12.5mg and Amlodipine 5 mg. Study design: 2 weeks washout, 8 weeks treatment period.
- Trial name
- NCT00426478
- Testing
- Valsartan plus Hydrochlorothiazide (80mg/12.5mg), Amlodipine (5mg)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Novartis
Pre-hypertension, Hypertension
Potassium-Magnesium Citrate as a Blood Pressure Lowering Agent in Hypertensive Patients
The goal of this study is to compare the effects of Potassium Magnesium Citrate to Potassium Chloride on blood pressure among patients with pre-hypertension or mild hypertension.
- Trial name
- NCT01074918
- Testing
- Potassium, Magnesium, Citrate, Potassium Chloride
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypertension, Obesity
The Effect of Oral SPM Supplementation on INflammation-induced Vascular Ageing in Obese Hypertensive Patients
Cardiovascular risk factors such as obesity, diabetes, high blood pressure, high cholesterol, or smoking are associated with an increased risk of events such as myocardial infarction, stroke, or peripheral artery disease.
- Trial name
- SPIN-VA (NCT07038252)
- Testing
- Oral SPM-enriched marine oil (LIPINOVA)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Glaucoma, Ocular Hypertension
Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive Patients
This is an observational study involving patients with glaucoma, those with ocular hypertension and healthy subjects. The aim of the study is the long term evaluation of functional, vascular and morphological changes in glaucoma…
- Trial name
- Ippocrate (NCT06827535)
- Where
- 5 sites in Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Mario Stirpe
Type 2 Diabetes Mellitus, Hypertension
Evaluation of Improved Outcomes Among Ambulatory Diabetes and/or Hypertensive Patients - an Intervention Study (CPCLINT)
The goal of this interventional study is to compare improved outcomes among diabetes and/or hypertensive patients sequel to educational intervention.
- Trial name
- CPCLINT (NCT05996601)
- Testing
- Educational intervention
- Where
- Nigeria
- Volunteers
- 400 people
- Sponsor
- University of Ibadan
Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism
Kidney Stiffness Measured by Ultrasound in Patients With High Blood Pressure and Healthy Volunteers
High blood pressure (hypertension) is a leading cause of kidney damage, but detecting early kidney changes remains challenging with currently available tools.
- Conditions
- Arterial Hypertension, Chronic Kidney Disease, Primary Aldosteronism, Arterial Stenosis
- Trial name
- K-STRESS (NCT07914075)
- Where
- Italy
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
Hypertension, Obesity
Lifestyle Internet-Based Intervention On Hypertensive Patients With Overweight Or Obesity
This study aims to analyze the effects of a 3 months duration self-applied online program, composed of 9 modules focused on promoting healthy lifestyle habits (healthy eating and increased physical activity), on obese or…
- Trial name
- IBI-HTA (NCT04426877)
- Testing
- Experimental group, Control group
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Cardenal Herrera University
Intracerebral Hemorrhage, Hypertension
Huayu Jiedu Formula (FTFY-919) Granules Versus Traditional Decoction for Acute Hypertensive Intracerebral Hemorrhage
This is a multicenter, randomized, double-blind, controlled, non-inferiority clinical trial to evaluate the efficacy and safety of Huayu Jiedu Formula (FTFY-919) Chinese medicine formula granules compared with traditional…
- Trial name
- CHAIN3 (NCT07801599)
- Testing
- Huayu Jiedu Formula (FTFY-919) Granules, Huayu Jiedu Formula (FTFY-919) Traditional Decoction
- Volunteers
- 300 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Hypertension, Type 2 Diabetes Mellitus
Comparison of Valsartan With Amlodipine in Hypertensive Patients With Glucose Intolerance
Various guidelines recommended angiotensin converting enzyme (ACE) inhibitors or angiotensin Ⅱ receptor-1 blockers (ARBs) for hypertensive patients with diabetes on the basis of the cardiac- and reno-protective effects of these…
- Trial name
- NCT00129233
- Testing
- Valsartan, Amlodipine
- Where
- Japan
- Volunteers
- 1,150 people
- Sponsor
- Nagoya University
Hypertension, Diabetes Mellitus, Type 2
A Study on Ca Blocker Versus AII Antagonists in Hypertension With Type 2 Diabetes
The antihypertensive effect of the increased dose of angiotensin II receptor blocker (AII antagonist) is compared with that of the additional combined use of amlodipine in hypertensive patients with Type 2 diabetes mellitus, who…
- Trial name
- NCT00144144
- Testing
- Angiotensin II receptor antagonists, Calcium channel blocker
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Advanced-J