Clinical trials: Hypertensive Patients
Uncontrolled Hypertension
EuroNetrod HTN OFF-Med Study of Renal Denervation With NetrodTM Six-electrode Radiofrequency RDN System
This randomized controlled investigation aims to evaluate the efficacy and safety of the Netrod™ RDN system in patients with uncontrolled primary hypertension in the absence of antihypertensive medication, comparing the outcomes…
- Trial name
- EuroNetrod (NCT06722651)
- Testing
- Netrod™ six-electrode radiofrequency renal denervation system
- Where
- Switzerland
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Arterial Hypertension, Hypertension
Validity of 6 Minutes Stepper Test in Hypertension
The six minutes stepper test (6MST) was used assess exercise capacity of individuals having different chronic conditions. In the literature, there are some validation studies analyzing validity of 6MST.
- Trial name
- NCT06087172
- Testing
- Six Minutes Stepper Test (6MST)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ebru Calik Kutukcu
Hypertension, Diabetic Nephropathies
A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study)
A number of blood pressure lowering drugs in the class known as angiotensin receptor blockers (ARB) have been shown to slow the decline in kidney function of patients with type 2 diabetes, high blood pressure, and kidney disease.
- Trial name
- NCT00168857
- Testing
- telmisartan, losartan
- Where
- 109 sites in United States, Argentina and 8 more
- Volunteers
- 860 people
- Sponsor
- Boehringer Ingelheim
Blood Pressure
Comparative Effects of UE Aerobic and Resistance Training on Cardiorespiratory Fitness in Hypertensive Patients
simple random sampling into group A \& group B to collect data. Group A will be given upper extremity aerobic training and group B will be given upper extremity resistance training.
- Trial name
- NCT05936892
- Testing
- upper extremity aerobic training, upper extremity resistance training
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Hypertension
Observational Study to Investigate the Effectiveness of Eprosartan on Pulse Pressure (Teveten_MS)
The study is to identify the effectiveness of Eprosartan on pulse pressure in hypertensive patients with metabolic syndrome -Definition of pulse pressure (PP): Difference between systolic and diastolic blood pressure produced one…
- Trial name
- NCT02024100
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Handok Inc.
Hypertensive Emergency
a Study Evaluating the Safety and Efficacy of Clevidipine for Patients Who With Hypertensive Emergency and Sub-emergency
A Multicentre, Randomized, Double-blind, Parallel Design Phase III Study to Evaluate the efficacy and safety of QLG2071 Versus Cleviprex® in the Treatment of Hypertensive Emergency and Sub-emergency
- Trial name
- NCT05922436
- Testing
- QLG2071, Cleviprex®
- Volunteers
- 378 people
- Sponsor
- Qilu Pharmaceutical (Hainan) Co., Ltd.
Primary Hypertension
A Study of LY2623091 in Participants With High Blood Pressure
The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY2623091 in participants with high blood pressure.
- Trial name
- NCT02194465
- Testing
- LY2623091, Tadalafil, Spironolactone
- Where
- 43 sites in United States, Canada and 1 more
- Volunteers
- 304 people
- Sponsor
- Eli Lilly and Company
Hypertension
Efficacy and Safety of Valsartan/Amlodipine Combination in Hypertensive Patients Not Controlled With Valsartan Alone
This study will test the effectiveness and safety of a combination treatment in patients whose blood pressure is not controlled with a single medication
- Trial name
- NCT00170963
- Testing
- valsartan/amlodipine
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 1,018 people
- Sponsor
- Novartis
Hypertension, End Stage Renal Disease
RAAS Inhibitor Drugs in Dialysis Patients
Hypertensive haemodialysis patients are at high risk for cardiovascular events. This study was undertaken to ascertain whether the upstream of aliskirne, a direct renin inhibitor improves mortality and cardiovascular outcomes in…
- Trial name
- NCT01635387
- Testing
- aliskiren
- Volunteers
- 350 people
- Sponsor
- University of Campania Luigi Vanvitelli
Hypertension
BEtter Control of Blood Pressure in Hypertensive pAtients Monitored Using the HOTMAN® sYstem
The purpose of this study is to demonstrate that monitoring hemodynamic parameters and then applying a predefined algorithm of drug selection (i.e.
- Trial name
- BEAUTY (NCT01482364)
- Testing
- Integrated hemodynamic management (IHM) - HOTMAN System, Non Integrated Hemodynamic Management (Non-IHM) - HOTMAN System
- Where
- 5 sites in Estonia, France and 3 more
- Volunteers
- 183 people
- Sponsor
- Hemo Sapiens, Inc.
Open Angle Glaucoma, Ocular Hypertension
Efficacy and Safety Assessment of T2347 Versus Xalacom® in Ocular Hypertensive or Glaucomatous Patients
The objective of the study is to assess the efficacy and safety of T2347 (Latanoprost 0.005% + Timolol 0.5% unpreserved eye drops) versus Xalacom® in ocular hypertensive or glaucomatous patients initially treated, stabilised by…
- Trial name
- NCT02278614
- Testing
- T2347, Xalacom
- Where
- France
- Volunteers
- 242 people
- Sponsor
- Laboratoires Thea
Hypertension
Tissue Sodium in Pre-hypertensive Patients
Cardiovascular disease is the first common cause of death worldwide. Hypertension is the number one driving risk factor. Hypertension has long been associated with dietary salt intake.
- Trial name
- NCT02236520
- Testing
- Spironolactone, Chlorthalidone, Diet
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Hypertension, Vascular Function
Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.
This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health.
- Conditions
- Hypertension, Vascular Function, Fitness Testing, Metabolism Changes
- Trial name
- Antitension (NCT06823570)
- Testing
- Individualized exercise therapy, Lifestyle recommendations
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Transurethral Resection of the Prostate (TURP)
Changes of Upper and Lower Limb Blood Flow and Vascular Resistance in Hyperbaric Spinal Anesthesia for Transurethral Resection of the Prostate (TURP) Using Duplex Ultrasonography: Comparison of Normotensive and Hypertensive Patients
Changes of Upper and Lower Limb Blood Flow and Vascular Resistance in Hyperbaric Spinal Anesthesia for TURP Using Duplex Ultrasonography: Comparison of Normotensive and Hypertensive Patients.
- Trial name
- NCT01091779
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Immune System Profile During Hypertensive Cardiac Remodeling
Immunological Profile in Relation to Cardiac Geometry in Hypertension
It is commonly known that heart failure (HF) is the main cause of mortality and morbidity which affects about 15 million people in the world and is the primary chronic cause of death.
- Trial name
- NCT02165241
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Neuromed IRCCS
Anemia, Diabetes, Kidney Disease, Chronic, Hypertension
Study of Anemia in Chronic Kidney Disease (CKD) Among High-Risk Hypertensive and Diabetic Patients in Pakistan
The purpose of this study is to evaluate the prevalence of CKD-related anemia at an early stage through screening of high-risk patients in Pakistan at the level of physicians, cardiologists, and diabetologists.
- Trial name
- NCT02444845
- Where
- 3 sites in Pakistan
- Volunteers
- 246 people
- Sponsor
- Hoffmann-La Roche
Hypertension, High Cholesterol
Additive Effects of Pravastatin and Valsartan
The investigators hypothesize that pravastatin combined with valsartan may have additive effects in hypertensive, hypercholesterolemic patients.
- Trial name
- NCT01004237
- Testing
- pravastatin, valsartan, pravastatin+valsartan
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Gachon University Gil Medical Center
Open-Angle Glaucoma, Ocular Hypertension
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41
To compare intraocular pressure lowering effectiveness of a combination drug vs. two individual drugs dosed alone.
- Trial name
- NCT00047528
- Testing
- Alcon Investigational Agent
- Where
- United States
- Sponsor
- Alcon Research
Hypertension, Cardiovascular Risk
Effect of Pitavastatin on Coronary Flow Reserve in Hypertensive Patients
Although statins reduce cardiac events in hypertensive patients with cardiovascular risk factors, the effect of statins on coronary flow reserve (CFR) has not been examined in such patients.
- Trial name
- EPOCH (NCT02144922)
- Testing
- Pitavastatin, Control
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Asan Medical Center
Hypertension, Dialysis
Aliskiren or Amlodipine in Hypertensive Hemodialysed Patients
Hypertensive haemodialysis patients are at high risk for cardiovascular events. This study was undertaken to ascertain whether aliskiren, a direct renin inhibitor, compared with amlodipine, a calcium channel blocker, reduces…
- Trial name
- NCT01394770
- Testing
- Aliskiren
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- University of Campania Luigi Vanvitelli