Clinical trials: Hypertrophic Scarring
Hypertrophic Scar
Safety, Tolerability, Pharmacokinetics, Immunogenicity and Efficacy of STP705 in Adult Patients With Hypertrophic Scars
Adult patients with hypertrophic scars 30 Subjects in Dose Escalation 20 Subjects in Dose Expansion Intrascar injection of STP705 weekly for 4 weeks
- Trial name
- NCT05196373
- Testing
- STP705
- Where
- China
- Sponsor
- Sirnaomics
Scar Tissue, Hypertrophic Scar
Effectiveness of Dry Needling in Linear Scar Tissue
Scar tissue can cause serious complications that significantly impact a patient's quality of life. Common complications include stiffness and contractions, which can restrict joint mobility and make daily activities challenging.
- Conditions
- Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar
- Trial name
- NCT06033430
- Testing
- True dry needling
- Where
- 2 sites in United States, Iran
- Volunteers
- 80 people
- Sponsor
- Iran University of Medical Sciences
Burn Scar, Hypertrophic Scar
Characterization of Dyschromic Hypertrophic Scar
Currently, there are limited prevention or treatments available for dyschromia in burn hypertrophic scars (HTSs). The limited available techniques involve transferring melanocytes from unaffected areas to the scar to adjust…
- Conditions
- Burn Scar, Hypertrophic Scar, Hyperpigmentation, Hypopigmented Scar
- Trial name
- NCT04619589
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Burn Scars
Laser Therapy for Treating Hypertrophic Burn Scars in Children
Pulse-dye laser therapy has been used to treat the redness, tightness and discomfort of hypertrophic scars resulting from burn injuries. To date the effectiveness of laser therapy on children's burned scars has not been measured.
- Trial name
- LaserTherapy (NCT01653691)
- Testing
- Pulse-Dye Laser
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Hypertrophic Scars, Keloids
CICATRIX in the Treatment of Hypertrophic Scars and Keloids Scars
The purpose of the study is to assess the efficacy of CICATRIX (Asian Gotu Kola or Pennywort) usage in the treatment of Hypertrophic scars and keloids.
- Trial name
- NCT00993005
- Testing
- Cicatrix
- Where
- Cuba
- Volunteers
- 90 people
- Sponsor
- Catalysis SL
Itchiness, Hypertrophic Scar
The Use of Botulinum Toxin in the Treatment of Itching From Hypertrophic Scar -- A Randomised Controlled Trial
Hypertrophic scar, a disfiguring tissue reaction to trauma, occurred in around 20 % of the population. The patients with hypertrophic scar usually seek medical assistance not just for the annoying appearance but mostly due to the…
- Conditions
- Itchiness, Hypertrophic Scar, Botulinum Toxin
- Trial name
- NCT02168634
- Testing
- Botulinum Toxins
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Hypertrophic Scars, Post-burn Scars
Nano-Fat Grafting for Post-Burn Scars on the Chest, Shoulders, and Back
This study aims to evaluate the effectiveness of nano-fat grafting in treating hypertrophic scars caused by burns on the chest, shoulders, and back.
- Conditions
- Hypertrophic Scars, Post-burn Scars, Burns
- Trial name
- NCT07557472
- Testing
- Autologous Nano-Fat Grafting
- Volunteers
- 55 people
- Sponsor
- Assiut University
Acne Scars - Mixed Atrophic and Hypertrophic
Tripeptide/Hexapeptide Topical and Hybrid Laser Treatment for Acne Scarring
To evaluate the efficacy of a tripeptide/hexapeptide topical (Alastin Regenerating Skin Nectar with TriHex Technology®) in wound healing and scar reduction following Erbium:YAG hybrid resurfacing laser for acne scarring compared…
- Trial name
- NCT04606134
- Testing
- Hybrid fractional laser, Alastin Regenerating Skin Nectar with TriHex Technology, Cetaphil face cream
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Burn Scar
Nonsilicone Gel Sheet for Burn Hypertrophic Scars
Overview: The application of gel sheets holds promise for both the prevention and treatment of hypertrophic scar after deep dermal injuries.
- Trial name
- NCT05429411
- Testing
- Silicone gel
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hypertrophic Surgical Scar
Clinical Trial to Evaluate the Safety and Efficacy of Scarclinic™ Thin in Surgical Scars
Compare the efficacy and safety of Scarclinic™Thin and Scarclinic™ Normal for the treatment of surgical scars. Participant: 40 Treatment period : 3 months Medical device: Scarclinic™Thin , Scarclinic™ Normal Randomization: Table…
- Trial name
- NCT01689857
- Testing
- Scarclinic™ Thin, Scarclinic™ Normal
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn
Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients
Burn patients very commonly develop abnormal scars after injury which can be red, raised or elevated, painful and very itchy. They can prevent normal movement of hands and other joints and lead to ugly deformities which makes…
- Conditions
- Burn; Multiple Body Regions, Max. Second Degree, Third-Degree Burn, Burn Degree Second
- Trial name
- NCT04685577
- Testing
- Nefopam
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Surgical Incision, Surgery--Complications
Zinc Oxide Versus Petrolatum Following Skin Surgery
Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this…
- Conditions
- Surgical Incision, Surgery--Complications, Surgical Wound, Surgical Site Infection
- Trial name
- NCT03561376
- Testing
- Topical zinc oxide vs. petrolatum post-surgical scars
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melissa Pugliano-Mauro
Hypertrophic Scar
Pulsed High Intensity Laser Versus Extracorporeal Shockwave Therapy on Hypertrophic Scar Post Burn
The goal of this clinical trial stydy : is to compare between the effect of pulsed high intensity laser and extracorporeal shockwave therapy on hypertrophic scar on post burned patients.
- Trial name
- NCT06803472
- Testing
- pulsed high intensity laser therapy, Extracorporeal shockwave therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Scar
Effect of PDRN in Post-operative Scars
The investigators aimed to evaluate the efficacy of PDRN administration in early wound healing phase on prevention of post-operative scars after open thyroidectomy.
- Trial name
- NCT05149118
- Testing
- Polydeoxyribonucleotide (PDRN)
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Bundang Hospital
Wound Heal, Scar
Scar Tissue Analysis After Intraoperative Application of Stromal Vascular Fraction Cells Into Suture Line
The study will evaluate the effect of intradermal injection of stromal vascular fraction into suture line on wound healing and scarring.
- Conditions
- Wound Heal, Scar, Hypertrophic Scar, Delayed Wound Healing
- Trial name
- NCT04238468
- Testing
- Intradermal stromal vascular fraction injection
- Where
- Slovenia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Katarina Zivec
Scar Keloid
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars
Summary: Keloids and hypertrophic scars are benign fibrous growth, differing mainly by overgrowth beyond the initial defect in keloid whereas hypertrophic scar is confined to initial lesion and tends to regress over the years.
- Trial name
- NCT04812626
- Testing
- 5-Fluorouracil
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Burn Scar, Scar
Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars
This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment.
- Trial name
- SMOOTH (NCT04736251)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Naiem Moiemen
Burns, Hypertrophic Scar
Effect of Elastic Bandage With Tension on the Inflammatory Response of Hypertrophic Scars
Burns can lead to lesions of total thickness, which extend the reticular layer of the dermis requiring a healing process, resulting in aesthetic problems, hypertrophic and functional scars that causes the patient a state of low…
- Trial name
- NCT04643223
- Testing
- kinesio tape with tension, kinesio tape without tension
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Hypertrophic Scar
Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic Scar
The goal of this clinical trial study: is to determine the effect Botulinum toxin type A iontophoresis in hypertrophic scars for post burned patients.
- Trial name
- NCT05771623
- Testing
- Iontophoresis drug delivery device, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypertrophic Scar
An Innovative Image-Based Method for Extensibility Assessment
This study uses a mixed-method design combining a quasi-experimental, single-group pre-post intervention with a methodological validation approach.
- Trial name
- NCT06940999
- Testing
- Traditional physical therapy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University