Clinical trials: Hypocalcemia
Sepsis, Septic Shock
Ionized Calcium as a Severity Marker in Septic Shock Patients
Sepsis is a serious condition where the body has an extreme, dysregulated response to an infection, often leading to life-threatening organ dysfunction.
- Conditions
- Sepsis, Septic Shock, Hypocalcemia
- Trial name
- NCT07812051
- Volunteers
- 160 people
- Sponsor
- Assiut University
Hypocalcemia, Total Thyroidectomy
Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy
The intensity of parathyroid fluorescence that occurs after intravenous injection of indocyanine green during the performance of a total thyroidectomy correlates with postoperative parathyroid function and could be used as a…
- Conditions
- Hypocalcemia, Total Thyroidectomy, Hypoparathyroidism Postprocedural
- Trial name
- NCT04012476
- Testing
- Indocyanine Green
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Son Espases
Hypomagnesemia, Hypocalcemia
Hypomagnesemia and Hypocalcemia Association Following Thyroidectomy
Magnesium plays a role in the active transport of calcium (Ca+2) and potassium ions across cell membranes. Most of it is intracellular or in the bone , however less than 1% of magnesium is in the blood serum.
- Conditions
- Hypomagnesemia, Hypocalcemia, Hypomagnesemia With Secondary Hypocalcemia
- Trial name
- NCT04351451
- Testing
- thyroidectomy
- Where
- Saudi Arabia
- Volunteers
- 74 people
- Sponsor
- King Saud University
Hypocalcemia
Clinical Assessment of Low Calcium In traUMa (CALCIUM)
Major trauma frequently occurs in the deployed, combat setting and is especially applicable in the recent conflicts with explosives dominating the combat wounded.
- Trial name
- CALCIUM (NCT05885256)
- Testing
- Amending current standard trauma order set
- Where
- United States
- Volunteers
- 391 people
- Sponsor
- Brooke Army Medical Center
Chronic Hypoparathyroidism
Efficacy of Calcium Citrate Versus Calcium Carbonate for the Management of Chronic Hypoparathyroidism
Hypoparathyroidism is an endocrinopathy characterized by a deficient secretion or action of PTH associated with low calcium level.
- Trial name
- NCT03425747
- Testing
- Calcium Carbonate, Calcium Citrate
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Campus Bio-Medico University
Thyroid Diseases
Vit D Role in Post Thyroidectomy Hypocalcemia
Hypocalcemia after total thyroidectomy is usually transient but it is of main concern as it requires either prolonged stay in the hospital or readmission.
- Trial name
- NCT04094493
- Testing
- vit D
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
DiGeorge Anomaly, DiGeorge Syndrome
Thymus Transplantation Dose in DiGeorge #932
One purpose of this study is to determine whether the amount of cultured thymus tissue implanted into DiGeorge anomaly infants has any effect on the immune outcome.
- Conditions
- DiGeorge Anomaly, DiGeorge Syndrome, Complete DiGeorge Anomaly, Complete DiGeorge Syndrome
- Trial name
- NCT00576836
- Testing
- Cultured Thymus Tissue Implantation (CTTI), Cultured Thymus Tissue Implantation with Parathyroid Transplantation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Hyperparathyroidism, Secondary
Extension Study of Etelcalcetide in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis
This study is designed to describe the long-term safety and efficacy of etelcalcetide (AMG 416) for the treatment of SHPT in adults with CKD on hemodialysis.
- Trial name
- NCT01785875
- Testing
- Etelcalcetide
- Where
- 208 sites in United States, Australia and 15 more
- Volunteers
- 891 people
- Sponsor
- Amgen
Hyperparathyroidism
Energy Specific Far Infrared Radiation Treatment for Hyperparathyroidism
A study to determine the possibility of using far infrared radiation to treat Hyperparathyroidism.
- Trial name
- NCT00573573
- Testing
- Far Infrared Radiation
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- GAAD Medical Research Institute Inc.
Secondary Hyperparathyroidism
Comparison of Total Parathyroidectomy With and Without Autotransplantation
The purpose of this study is to compare short-term and long-term efficacy of total parathyroidectomy with autotransplantation and total parathyroidectomy without autotransplantation for Secondary hyperparathyroidism.
- Trial name
- NCT02536287
- Testing
- total PTX without autotransplantation, total PTX with autotransplantation
- Where
- China
- Volunteers
- 96 people
- Sponsor
- The Second Hospital of Anhui Medical University
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Hemorrhage, Hypocalcemia
The No-Tie Technique Using the Harmonic Scalpel in Total Thyroidectomy With Central Neck Dissection: A Prospective Randomized Study
To investigate the safety and efficacy of the no-tie technique using the harmonic scalpel (HS) in terms of the operating time and complications in total thyroidectomy with central neck dissection (CND).
- Conditions
- Hemorrhage, Hypocalcemia, Vocal Cord Palsy
- Trial name
- NCT00506103
- Where
- South Korea
- Sponsor
- Soonchunhyang University Hospital
Autosomal Dominant Hypocalcemia (ADH)
Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1
The primary purpose of the study is to understand the effectiveness, safety, and tolerability of encaleret when compared to standard of care (SoC) treatment in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1).
- Trial name
- CALIBRATE (NCT05680818)
- Testing
- Encaleret, Standard of Care
- Where
- 25 sites in United States, Australia and 8 more
- Volunteers
- 67 people
- Sponsor
- Calcilytix Therapeutics, Inc., a BridgeBio company
Hyperparathyroidism, Secondary
Study to Assess the Impact on Calcium Levels When Hemodialysis Patients With Secondary Hyperparathyroidism (SHPT) Switch From Cinacalcet to Etelcalcetide
This is a multicenter, multiple-dose, single-arm, open-label study to assess the impact on serum corrected calcium levels when switching patients from cinacalcet to etelcalcetide (AMG 416).
- Trial name
- NCT01932970
- Testing
- Etelcalcetide
- Where
- 40 sites in United States
- Volunteers
- 158 people
- Sponsor
- Amgen
Hypoparathyroidism
A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)
Recombinant human parathyroid hormone, also known as if rhPTH(1-84), is a medicine to treat people with Hypothyroidism. The main aim of this study is to learn if rhPTH(1-84) can improve symptoms in adults with hypoparathyroidism.
- Trial name
- NCT03324880
- Testing
- rhPTH (1-84)
- Where
- 40 sites in United States, Belgium and 11 more
- Volunteers
- 93 people
- Sponsor
- Shire
Autosomal Dominant Hypocalcemia
ADH1 and ADH2 Disease Monitoring Study (DMS)
A global, multi-center, Disease Monitoring Study (DMS) in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1) or Autosomal Dominant Hypocalcemia Type 2 (ADH2) designed to characterize ADH1 and ADH2 disease…
- Trial name
- CLARIFY (NCT05227287)
- Where
- 27 sites in United States, Australia and 11 more
- Volunteers
- 95 people
- Sponsor
- Calcilytix Therapeutics, Inc., a BridgeBio company
Paget's Disease of the Bone, Hypocalcemia
Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the Need to Take Daily Supplemental Calcium and Vitamin D to Patients With Paget's Disease Treated With Reclast®
This study will evaluate the impact of investigator and patient education and educational materials to foster calcium and vitamin D supplementation to mitigate the potential for hypocalcemia post Reclast® administration in…
- Trial name
- NCT00668200
- Testing
- Reclast (ZOL446, zoledronic acid), Calcium, Vitamin D
- Where
- 9 sites in United States
- Volunteers
- 81 people
- Sponsor
- Novartis Pharmaceuticals
Thyroid
Complications After Thyroid Surgeries: 10 Years' Experience
Thyroidectomy is one of the commonest elective surgeries in surgical practice nowadays. It is associated with wide range of complications, from unnoticed events up to lifelong problems and even life-threatening complications.
- Trial name
- NCT05699304
- Testing
- Thyroidectomy
- Where
- Egypt
- Volunteers
- 241 people
- Sponsor
- South Valley University
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Hypocalcemia, Vitamin D Deficiency
The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients.
Glucocorticoids are well known for their analgesic, anti-inflammatory, immunomodulatory and anti-emetic effects. Recovery time after thyroid surgery may depend on several factors, such as postoperative pain, nausea and vomiting…
- Conditions
- Hypocalcemia, Vitamin D Deficiency, Postoperative Complications, Postoperative Nausea
- Trial name
- Dexa (NCT04412694)
- Testing
- Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland)., Preoparative blood laboratory tests, Postoperative laboratory blood tests at 6 hour
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz