Clinical trials: Hypoesthesia
Cervical Radiculopathy, Cervical Radicular Pain
Effects of Exercises and Electrical Current Application Aiming to Strengthen Neck and Shoulder Blades Muscles on Symptoms of a Pinched Nerve in the Neck
Cervical Radiculopathy (CR) is an objective loss of sensory and/or motor function as a result of compression or irritation of the cervical spinal nerve root.
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Neck Pain, Numbness
- Trial name
- NCT07375823
- Testing
- Exercise Therapy, Superimposition of electrical muscle stimulation on active movement
- Where
- Cyprus
- Volunteers
- 50 people
- Sponsor
- European University of Lefke
Symptomatic Cervical Disc Disease
2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease…
- Trial name
- SMART (NCT04012996)
- Testing
- prodisc C SK and/or Vivo, Mobi-C Cervical Disc
- Where
- 30 sites in United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Centinel Spine
Ipsi- and Contralateral Hypoesthesia
A Human Experimental Model for Neuropathic Pain Using Combined Application of Capsaicin and Local Anesthetics
Main of the present study was to develop a model of concomitant C-fibre block and sensitization eliciting spontaneous pain as well applying topical capsaicin and local anesthetics (LA) to examine the sensory alterations after…
- Trial name
- NCT01540877
- Testing
- Application of capsaicin 0.6%, Application of local anesthetics (EMLA plaster), Application of 1 capsaicin 0.6% and 2. EMLA
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Carpal Tunnel Syndrome (CTS), Nerve Conduction
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound Versus Nerve Conduction Studies (NCS)
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound vs. Nerve Conduction Study (NCS) This clinical study aims to determine whether ultrasound can be as practical as NCS in…
- Conditions
- Carpal Tunnel Syndrome (CTS), Nerve Conduction, Ultrasound
- Trial name
- NCT06926777
- Testing
- Nerve Conduction Study
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Combined Military Hospital Kohat Pakistan
Head Cancer, Neck Cancer
Neurosensorial Disorder and Pain in Oral Cavity and Oropharynx Cancer Traited Patients (OCAPA)
Following preliminary studies carried out in our department on these subject and subjective findings during clinical examinations, it has been shown that pain is a symptom that is rarely reported following treatment.
- Conditions
- Head Cancer, Neck Cancer, Chronic Pain
- Trial name
- OCAPA (NCT04673981)
- Testing
- diagnostic tes for neuropathic pain
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Skin Numbness and Kneeling Ability
Comparison of Midline With Lateral Skin Incision in Simultaneous Bilateral TKA
This is a RCT which compare skin numbness, kneeling ability and functional outcome between midline incision and lateral incision in patients undergoing simultaneous bilateral TKA
- Trial name
- NCT04240847
- Testing
- Skin incision
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Thammasat University
Carpal Tunnel Syndrome, Susceptibility to
Non-surgical Intervention for Carpal Tunnel Syndrome
This randomized controlled trial graduate student research study will explore the effect of non-surgical intervention of the dorsal application of Kinesio Tape for carpal tunnel syndrome, and forearm wrist hand pain.
- Trial name
- NCT03360344
- Testing
- Kinesio 12 inch Tape, Kinesio 4 inch Tape, Cock up Splint and Lumbrical exercises
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Parkinson Disease
Effects of Cervical Stabilization Exercises and Vibration Application in Individuals With Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease that causes a progressive decrease in motor functions, which is caused by the influence of dopaminergic pathways in the substantia nigra (SN).
- Trial name
- NCT05837715
- Testing
- Chattanooga Stabilizer pressure biofeedback, VibraSens - Focal Vibration Therapy (TechnoConcept - France), Telerehabilitation
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Cancer-related Problem/Condition, Neurotoxicity
Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer
RATIONALE: Electrical stimulation pain therapy may help relieve chronic pain and numbness caused by chemotherapy. PURPOSE: This pilot trial studies electrical stimulation pain therapy in treating chronic pain and numbness caused…
- Conditions
- Cancer-related Problem/Condition, Neurotoxicity, Pain, Peripheral Neuropathy
- Trial name
- NCT01196442
- Testing
- electrical stimulation pain therapy, questionnaire administration
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Virginia Commonwealth University
Anesthesia, Local, Anesthesia, Dental
Behavior of Children Related to Numbness After Dental Local Anesthesia
In children, behavior management is critical to the success of pediatric dental procedures. Most of the studies on local anesthesia performed in children deal with the question how to avoid or minimize pain during injection.
- Trial name
- NCT00363207
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pain Management, Thoracic Trauma
Comprehensive Multicenter Study on the Management of Acute Pain Following Thoracic Combat-Related Trauma in Ukraine
This study is a multicenter clinical trial conducted in Vinnytsia, Rivne, and Lviv, Ukraine, focusing on the management of acute pain following thoracic injuries sustained during combat.
- Conditions
- Pain Management, Thoracic Trauma, Pulmonary Function, Quality of Life
- Trial name
- CMS-APT-UA (NCT07380789)
- Testing
- Cryoablation, Radiofrequency ablation alone
- Where
- Ukraine
- Volunteers
- 50 people
- Sponsor
- Lviv National Medical University
Haemodialysis-induced Symptom
Symptom Management Program for Hemodialysis Patients
Self-management intervention may decrease symptom burden and improve functioning over time.
- Trial name
- NCT01620580
- Testing
- Self-management, Dietary Information
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Diabetic Neuropathy, Chemotherapy Induced Neuropathy
A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy
A clinical outcomes study measuring reduction in pain and numbness experienced in four types of peripheral neuropathy patients during 60 day administration of the an amino acid formulation.
- Conditions
- Diabetic Neuropathy, Chemotherapy Induced Neuropathy, HIV Neuropathy, Trauma Induced Neuropathy
- Trial name
- Neuron012703 (NCT01537705)
- Testing
- Neuron012703 (Medical Food)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Targeted Medical Pharma
Obesity, Hypesthesia
Post-bariatric Abdominoplasty: Skin Sensation Evaluation
The purpose of this study is to quantify the skin sensation of the anterior abdominal wall of the post-bariatric patients submitted to anchor-line abdominoplasty without flap undermining.
- Trial name
- NCT00831610
- Testing
- Bariatric surgery (Roux-en-Y Gastric Bypass) + Post-bariatric abdominoplasty., Roux-en-Y gastric bypass (bariatric surgery) + Post-bariatric abdominoplasty (without flap undermining)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Penile Numbness
Vacuum Therapy for the Treatment of Penile Numbness/Sensory Changes
This is a prospective, uncontrolled, Hypothesis generating study. A total of eight adult male participants experiencing penile insensitivity will be recruited through the Ottawa Hospital's Men's Health Clinic.
- Trial name
- NCT07171567
- Testing
- Vacuum erection device
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Knee
Effect of J-Shaped Incision After Total Knee Arthroplasty (J-TKA)
This prospective randomized controlled trial evaluates whether a modified J-shaped skin incision can reduce peri-incisional numbness after primary total knee arthroplasty (TKA) compared with the conventional midline skin…
- Trial name
- NCT07514598
- Testing
- Conventional Midline Incision, J-shaped Incision
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Chemotherapy-induced Peripheral Neuropathy
Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN)
The purpose of the study is to determine the validity of a point-of-care nerve conduction device (NeuroMetrix) and Rydel-Seiffer tuning fork in assessing the level of peripheral neuropathy in patients with chemotherapy-induced…
- Trial name
- NCT04092764
- Testing
- Electroacupuncture, NeuroMetrix, Rydel-Seiffer tuning fork
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Trigeminal Neuralgia
Observational Study on the Treatment of Trigeminal Neuralgia by Radiosurgery
This study aims to evaluate the outcome of patient treated by radiosurgery on LINAC with high dose rate for classical trigeminal neuralgia
- Trial name
- NATURE (NCT05677243)
- Where
- Monaco
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Princesse Grace
Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
The goal of this phase II/III randomized clinical trial is to evaluate the effect of adding rectal ozone therapy to the usual management of patients with paresthesia (numbness and/or tingling) due to chemotherapy-induced…
- Conditions
- Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness, Tingling
- Trial name
- OzoParQT (NCT06706544)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Anesthesia, Dental
Study of NV-101 for Safety and Efficacy in Pediatric Dental Patients Undergoing Procedures
This Phase 2 clinical study is designed as a multicenter, randomized, blinded, controlled study to evaluate the safety and efficacy of NV-101 in approximately 150 children 4 to 11 years of age.
- Trial name
- NCT00309322
- Testing
- Phentolamine Mesylate (NV-101)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Novalar Pharmaceuticals, Inc.