Clinical trials: Hypoestrogenism
Menopause, Hypoestrogenism
Analysis of the Hormonal Implant and Transdermal Estradiol Gel in Climacteric Women
An open-label, prospective clinical study will be conducted to monitor serum concentration and pharmacokinetic profiles following the subcutaneous implantation of six silicone hormone implants (delivering a total dose of 300 mg…
- Conditions
- Menopause, Hypoestrogenism, Hormonal Therapy
- Trial name
- ARESI (NCT07754630)
- Testing
- implantable estradiol, OESTROGEL - transdermal gel, PENTRAVAN - transdermal gel
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Nutrindo Ideais Research Center
Recurrent Urinary Tract Infection, Hypoestrogenism
Adherence to Vaginal Estrogen Therapy in Hypoestrogenic Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn about medication adherence to difference types of vaginal estrogen in women with low levels of estrogen (for example, post-menopausal women) who have recurrent urinary tract infections.
- Trial name
- NCT06353269
- Testing
- Estring Vaginal Product, Vagifem, Estrace 0.01% Vaginal Cream
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cystic Fibrosis, Hypoestrogenism
Estrogen Supplementation and Bone Health in Women With CF
The goal of this study is to learn about the role of estrogen and other hormones in bone development in adolescent and young adult women with cystic fibrosis (CF).
- Trial name
- STURDY (NCT05704036)
- Testing
- Transdermal estrogen, Progesterone
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Johns Hopkins University
Climacteric Syndrome, Menopause
Pharmacokinetic Aspects of 25-mg Estradiol Pellet in Climacteric Women
A single center, prospective, open-label clinical study will be conducted, to monitor serum concentration and pharmacokinetic profile after subcutaneous implantation of a 25mg-estradiol bioabsorbable implant in postmenopausal…
- Conditions
- Climacteric Syndrome, Menopause, Hypoestrogenism
- Trial name
- CLARA (NCT06136208)
- Testing
- s.c 25 mg estradiol pellet
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Science Valley Research Institute
Cognitive Side Effects of Cancer Therapy, Hypoestrogenism
ENDO-BRAIN: Effects of Endocrine Adjuvant Therapy with Aromatase Inhibitors on the Cognitive Function of Breast Cancer Patients
The principal aim of this prospective observational study is to investigate the cognitive function of breast cancer patients that use AI, comparing it with age-matched healthy controls, utilizing cognitive assessments and…
- Trial name
- ENDO-BRAIN (NCT06606535)
- Testing
- validated questionnaires, functional MRI, Optical Coherent Tomography Angiography
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Bone Demineralization, Hypoestrogenism
The Kampala Women's Bone Study
The primary objective of this study is to address critical safety questions with concurrent TDF-based PrEP and DMPA use. We hypothesize that young women using TDF-based PrEP and DMPA will have lower bone acquisition and altered…
- Conditions
- Bone Demineralization, Hypoestrogenism, Subclinical Kidney Injury, Bone Microarchitecture
- Trial name
- NCT03464266
- Testing
- FTC/TDF and DMPA, FTC/TDF, DMPA
- Where
- Uganda
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hypoactive Sexual Desire Disorder, Vulvovaginal Disease
Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.
The regulation of clitoral vascularization by sex steroids is still under-investigated. We aimed to explore the effects of 6 months transdermal Testosterone (T) therapy on clitoral color Doppler ultrasound (CDU) parameters in…
- Conditions
- Hypoactive Sexual Desire Disorder, Vulvovaginal Disease, Menopause Related Conditions, Dyspareunia (Female Excluding Psychogenic)
- Trial name
- TESTOFSD (NCT04336891)
- Testing
- Testosterone gel, Estradiol ovules, Moisturizer
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- University of Florence