Clinical trials: Hypoglycaemia
Diabetes Mellitus (DM), Hypoglycaemia
Evaluation of the Psychometric Properties of the Turkish Version of the Hypoglycaemia Self-Care Behaviour Scale
The aim of this study is to validate the validity and reliability of the Hypoglycaemia Self-Care Behaviour Scale, developed to assess hypoglycaemia self-care behaviours in patients with type 2 diabetes, through a prospective…
- Conditions
- Diabetes Mellitus (DM), Hypoglycaemia, Self Care
- Trial name
- NCT07316699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Type 1 Diabetes, Type 2 Diabetes Treated With Insulin
Implementation of Networked Continuous Glucose Monitoring With Telemetry Within the Intensive Care Unit (ICU-TeleCGM)
The aim of this observational study is to assess safety and implementation of continuous glucose monitors within the Intensive Care Unit.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes Treated With Insulin, Hyperglycemia, Intensive Care (ICU)
- Trial name
- ICU-TeleCGM (NCT07769138)
- Testing
- Dexcom G7, ViewsEMR telemetry
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Imperial College Healthcare NHS Trust
Infants of Diabetic Mothers, Placenta
Placental Weight in Infants of Gestational Diabetic Mothers
This prospective cross-sectional study examined the relationship between placental weight and early neonatal outcomes, such as blood glucose levels within the first 24 hours and early neonatal morbidities in infants born to…
- Conditions
- Infants of Diabetic Mothers, Placenta, Hypoglycaemia
- Trial name
- NCT07765784
- Testing
- Blood Glucose Level
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Hypoglycaemia, Diabete Mellitus
Developing a Colonoscopy Preparation Protocol for Patients With Diabetes
Patients with diabetes have less effective colonoscopy preparation when compared to nondiabetic patients. This leads to the possibility of missed polyps, longer procedural time and patient dissatisfaction.
- Conditions
- Hypoglycaemia, Diabete Mellitus, Colonoscopy (Ambulatory Patients)
- Trial name
- NCT07526103
- Testing
- timing of cleansing and procedure
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Queen's University
Diabetes Mellitus, Hyperglycaemia (Diabetic)
Validation of Remote Photoplethysmography for Non-Invasive Estimation of Blood Glucose and HbA1c
The goal of this observational study is to evaluate whether a non-invasive facial scan technology using remote photoplethysmography (rPPG) can accurately estimate blood glucose and HbA1c levels in adults living in the community…
- Conditions
- Diabetes Mellitus, Hyperglycaemia (Diabetic), Hyperglycaemia (Non Diabetic), Hypoglycaemia
- Trial name
- NCT07502690
- Where
- Indonesia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Hypoglycaemia
A Study of Endocrine, Metabolic, and Genetic Risk Factors of Pediatric Persistent Hypoglycemia at Sohag University Hospital
Glucose is the key metabolic substrate for tissue energy production. In the perinatal period, the mother supplies glucose to the fetus, and for most of the gestational period, the normal lower limit of fetal glucose concentration…
- Trial name
- NCT07533318
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Diabetes Mellitus Type 1, Glucose Metabolism Disorder
Real-life Follow-up of the Physical Activity in Type 1 Diabetes Participants Equipped With an Insulin Pump With Hybrid Closed Loop
This is a non-interventional, prospective, multi-site study conducted in France among adults with type 1 diabetes mellitus using automated insulin delivery (AID) systems and engaging in at least two exercise sessions per week…
- Conditions
- Diabetes Mellitus Type 1, Glucose Metabolism Disorder, Glycemic Control for Diabetes Mellitus, Fear of Hypoglycemia
- Trial name
- RAPPID (NCT07015970)
- Testing
- No Intervention: Observational Cohort
- Where
- 4 sites in France
- Volunteers
- 87 people
- Sponsor
- ISIS Diabete Service
Critical Illness, Hyperglycaemia
Intermittent Versus Continuous Glucose Monitoring in Intensive Care Unit
Glucose control is an important part of supportive care for critically ill patients. Achieving optimal glucose control in such situations is challenging due to frequent fluctuations in blood glucose levels.
- Conditions
- Critical Illness, Hyperglycaemia, Hypoglycaemia
- Trial name
- ICONS-ICU (NCT07088549)
- Testing
- Continuous glucose monitoring, Control Arm - standard of care
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Ljubljana
Hypoglycaemia
An Exploratory Study of 68Ga-DOTA-SEMA in Preoperative Precise Imaging of Patients with Glucagon-Like Peptide-1 Receptor (GLP1R) Positive Insulinomas
Traditional imaging techniques for insulinomas have a low detection rate. This study aims to evaluate the safety, internal radiation dosimetry, and targeted imaging capability of the novel GLP1R imaging agent, 68Ga-DOTA-SEMA, in…
- Trial name
- NCT06759740
- Testing
- 68Ga-DOTA-SEMA
- Where
- China
- Sponsor
- The Affiliated Hospital Of Southwest Medical University
Diabetes, Hypoglycaemia
How Common is Hypoglycaemia in Older People With Diabetes Who Fall?
The purpose of this study is to use 24 hour continuous glucose monitoring in older patients with diabetes who present with symptoms of falls, or dizziness, or confusion, that may indicate hypoglycaemia.
- Trial name
- NCT05470842
- Testing
- Continuous glucose monitoring (Dexcom G6)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of East Anglia
Post-bariatric Hypoglycaemia, Roux-en-Y Gastric Bypass
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 3
The overall aim of this study is to prevent hypoglycemic events in patients with hypoglycemia after a meal and to develop a sustainable hypoglycemia correction strategy.
- Trial name
- PBH Forecast (NCT05216926)
- Testing
- Timing of preventive action based on prediction model, Hypoglycaemia treatment at hypoglycaemia (usual care)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Lia Bally
Hypoglycemia, Reactive, Hypoglycaemia Night
CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia
Use of CGM to determine diagnosis in possible spontaneous or reactive hypoglycaemia. Use of CGM to aid treatment optimisation in spontaneous or reactive hypoglycaemia
- Conditions
- Hypoglycemia, Reactive, Hypoglycaemia Night, Hypoglycemia Non-Diabetic, Hypoglycemia Unawareness
- Trial name
- NCT04452396
- Testing
- use of continuous glucose monitoring
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Barts & The London NHS Trust
Post-bariatric Hypoglycaemia, Roux-en-Y Gastric Bypass
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 1
The overall aim of this study is to prevent hypoglycemic events in patients with hypoglycemia after a meal and to develop a sustainable hypoglycemia correction strategy.
- Trial name
- PBH Forecast (NCT05212207)
- Testing
- CGM, smartwatch, and electronic diary
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Lia Bally
Post-bariatric Hypoglycaemia, Roux-en-Y Gastric Bypass
Forecasting and Preventing Post-Bariatric Hypoglycaemia WP 2
The overall aim of this study is to develop a sustainable hypoglycemia correction strategy.
- Trial name
- PBH Forecast (NCT05250271)
- Testing
- 15 g dextrose, 5 g dextrose, Protein bar
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Lia Bally
Congenital Hyperinsulinaemic Hypoglycaemia, Octreotide Adverse Reaction
Efficacy and Safety Evaluation of Octreotide in the Treatment of Congenital Hyperinsulinemia
To analyze and evaluate the efficacy and safety of octreotide subcutaneous injection in the treatment of diazazine-ineffective congenital hyperinsulinemia (CHI) in children.
- Trial name
- BCH (NCT05171751)
- Testing
- Octreotide Injection
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Children's Hospital
Hyperinsulinemic Hypoglycemia, Post Gastrointestinal Tract Surgery Hypoglycaemia
Treatment Plan for an Individual Patient With Pasireotide for Hyperinsulinemic Hypoglycemia
Somatostatin analogues are a last resort for medical intervention in hyperinsulinemic hypoglycemia (HH). The hypoglycemia is very debilitating and can be even life threatening.
- Trial name
- NCT03103009
- Testing
- Pasireotide
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Colorado, Denver
Hypoglycaemia Neonatal
Prevention of Hypoglycaemia by Oral 40% Destrogel
Neonatal hypoglycemia understood as a reduction in plasma glucose can result in long-term neurological damage. Serious monitoring of neonatal blood glucose is indicated in patients at risk of hypoglycemia.
- Trial name
- NCT04185766
- Testing
- Administration of 40% glucose in gel (0.5 ml / Kg), Administration of 40% glucose in gel 1 ml / Kg)
- Where
- Italy
- Volunteers
- 172 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Type 1 Diabetes, Hypoglycaemia
DPP4inhibitors in Type 1 Diabetes
A small, pilot, randomised, cross over trial that investigates the potential for DPPIVi therapy to reduce insulin requirements in type 1 diabetes was studied.
- Trial name
- NCT01922817
- Testing
- Saxagliptin
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- University of Dundee
Type 1 Diabetes Mellitus, Nocturnal Hypoglycemia
Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia
The purpose of this study is to determine whether insulin degludec compared to insulin glargine can reduce the risk of symptomatic nocturnal hypoglycaemia in subjects with the greatest potential benefit from optimised insulin…
- Conditions
- Type 1 Diabetes Mellitus, Nocturnal Hypoglycemia, Recurrent Severe Hypoglycaemia
- Trial name
- HypoDeg (NCT02192450)
- Testing
- Insulin aspart/glargine, Insulin aspart/degludec
- Where
- Denmark
- Volunteers
- 149 people
- Sponsor
- Nordsjaellands Hospital
Gastrectomy, Oesophagectomy
Metabolic Consequences of Gastrointestinal Surgery
Surgery on the gastrointestinal (GI) tract results in profound changes to the metabolic profile. This is well described, including the rapid resolution of diabetes seen after bariatric surgery.
- Conditions
- Gastrectomy, Oesophagectomy, Dumping Syndrome, Hypoglycaemia
- Trial name
- MaS (NCT02836353)
- Testing
- Somatostatin, Rifaximin
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust