Clinical trials: Hypoglycemia Night
Diabetes Mellitus, Type I
Effect of the Fat Content of the Bedtime Snack on Overnight Hypoglycemia
Low blood sugar at night (called nocturnal hypoglycemia), can often happen without symptoms and can last for a long time. Doctors often suggest that patients take a bedtime snack to try to prevent low blood sugar at night from…
- Trial name
- NCT00493935
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes
Outpatient Pump Shutoff Pilot Feasibility and Efficacy Study
The purpose of this study is to see whether low blood sugar at night can be reduced by using a system that turns off the insulin pump automatically.
- Trial name
- NCT01591681
- Testing
- Pump suspension
- Where
- 3 sites in United States, Canada
- Volunteers
- 49 people
- Sponsor
- Jaeb Center for Health Research
Type I Diabetes
Monitoring of Nocturnal Hypoglycemia Using EarlySense Monitoring Device
This study observes the continuous measurement of breathing patterns, heart rate, restlessness, and tremor in sleep using the EarlySense ES 16 device as a tool in the management of hypoglycemia in pediatric type I diabetes…
- Trial name
- NCT00361608
- Testing
- EarlySense ES 16
- Where
- Israel
- Sponsor
- EarlySense Ltd.
Hypodlycemia
Early Detection of noctUrnal hypoglyCemiA in TypE 2 Diabetes Using Pulse Rate Variability Measured by a Smartwatch(EDUCATED-Smartwatch)
In patients with type 2 diabetes, it is necessary to identify and manage nocturnal hypoglycemia as early as possible, so as to reduce the damage caused by nocturnal hypoglycemia.We explore whether smartwatches can provide early…
- Trial name
- NCT05636007
- Testing
- Huawei Watch
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Sun Yat-sen University
Hypoglycemia, Diabetes Mellitus, Type 1
A Pilot Study of Nocturnal Hypoglycemia Prevention in Type 1 Diabetes Using the Vigilant Diabetes Management Companion
A single center pilot study assessing the Vigilant Diabetes Management Companion for the prevention of recurrent nocturnal hypoglycemia in type I diabetes patients.
- Trial name
- NCT02906891
- Testing
- Vigilant Diabetes Management Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- InSpark Technologies, Inc.
Diabetes Mellitus, Hypoglycemia (Diabetic)
Continuous Bloodsugar Monitoring System With a Sensor Compared to Fingerstick Bloodsugar Monitoring
This clinical trial aims to compare a continuous glucose monitoring system with traditional fingerstick blood glucose monitoring.
- Conditions
- Diabetes Mellitus, Hypoglycemia (Diabetic), Hypoglycemia Night, Hyperglycemia
- Trial name
- GLUCOSENS (NCT06473480)
- Testing
- Abbott FreeStyle Libre System 2 Plus, Abbott Freestyle Libre Pro
- Where
- 2 sites in Denmark
- Volunteers
- 329 people
- Sponsor
- Odense University Hospital
Diabetes, Hypoglycemia
Investigating the Relationship Between Nocturnal Glucose Levels and Motion During Sleep
In this study the investigators will explore whether the motion during sleep of people with diabetes changes as a function of the blood glucose levels.
- Conditions
- Diabetes, Hypoglycemia, Hyperglycemia
- Trial name
- Moonwalk (NCT05609175)
- Where
- Switzerland
- Volunteers
- 37 people
- Sponsor
- University of Bern
Type 1 Diabetes
MDRS for Prevention of Nocturnal Hypoglycemia
The investigators have developed a unique Remote \& Safety diabetes management system (MDRS) that offers real-time remote monitoring and control of glucose levels.
- Trial name
- MDRS (NCT01509157)
- Testing
- MDRS System (Remote & Safety diabetes management system), Continuous Glucose Monitoring
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Rabin Medical Center
Hypoglycemia, Reactive, Hypoglycaemia Night
CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia
Use of CGM to determine diagnosis in possible spontaneous or reactive hypoglycaemia. Use of CGM to aid treatment optimisation in spontaneous or reactive hypoglycaemia
- Conditions
- Hypoglycemia, Reactive, Hypoglycaemia Night, Hypoglycemia Non-Diabetic, Hypoglycemia Unawareness
- Trial name
- NCT04452396
- Testing
- use of continuous glucose monitoring
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- Barts & The London NHS Trust
Type 1 Diabetes
Outpatient Reduction of Nocturnal Hypoglycemia by Using Predictive Algorithms and Pump Suspension in Children
The purpose of this study is to see whether low blood sugar at night can be reduced by using a system that turns off the insulin pump automatically.
- Trial name
- PSO4 (NCT01823341)
- Testing
- Pump suspension algorithm
- Where
- 3 sites in United States, Canada
- Volunteers
- 97 people
- Sponsor
- Jaeb Center for Health Research
Diabetes Mellitus Type 2
Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 Diabetes
This exploratory double blind randomized active controlled study is designed to assess the effects of a treatment with therapeutical dosage of sitagliptin versus therapeutical dosage of glimepiride as add on therapy in patients…
- Trial name
- NCT02373865
- Testing
- Sitagliptin, Glimepiride
- Where
- Germany
- Volunteers
- 4 people
- Sponsor
- GWT-TUD GmbH
Diabetes Mellitus, Type 1, Adrenal Insufficiency
Hypoglycaemia (Low Blood Sugar) in Adults With Diabetes and Adrenal Failure
The purpose of this study is to measure how often low blood sugars occur in people who live with both adrenal insufficiency (AI) and diabetes and need to take insulin.
- Conditions
- Diabetes Mellitus, Type 1, Adrenal Insufficiency, Diabetes Mellitus Type 2 - Insulin-Treated
- Trial name
- HYPO-DIAD (NCT05806190)
- Testing
- Continuous Glucose Monitoring
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Imperial College Healthcare NHS Trust
Type1diabetes, Hypoglycemia
Prediction and Prevention of Nocturnal Hypoglycemia in Persons With Type 1 Diabetes Using Machine Learning Techniques
The objective is to develop a novel system to predict and prevent nocturnal hypoglycemia in type 1 diabetic (T1D) patients, focused in patients with multiple daily injections (MDI) therapy.
- Trial name
- NCT03711656
- Testing
- isCGM (intermittently scanned Continuous Glucose Monitoring), Physical exercise tracker
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Hospital Clinic of Barcelona
Type 1 Diabetes
An Outpatient Pump Shutoff Pilot Feasibility and Safety Study
The purpose of this study is to evaluate an overnight system that will turn off the insulin pump automatically if the system predicts that a low blood sugar is likely.
- Trial name
- PSO1 (NCT01736930)
- Testing
- Pump suspension
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms
Objective: to gain experience with in-home use of a modified algorithm that will dose insulin to minimize projected hyperglycemia overnight in addition to suspending the pump if hypoglycemia is projected overnight and to obtain…
- Trial name
- PHM2 (NCT02438189)
- Testing
- Predictive Hyperglycemia Minimization Algorithm, Predictive Hypoglycemia Minimization Algorithm
- Where
- 3 sites in United States, Canada
- Volunteers
- 33 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes, Nocturnal Hypoglycemia
Development and Assessment of Feasibility of Non-invasive Multiple Sensor Hypo-Sense as a Tool for Detection of Hypoglycemia
Hypo Sense is a non- invasive method for detection of hypoglycemia. The Hypo Sense combines an array of non-invasive sensors which monitors the patient's physiological parameters (heart \& respiration rate, perspiration, skin…
- Trial name
- Hypo-Sense (NCT02225379)
- Testing
- Hypo-Sense (non invasive sensor)
- Where
- Israel
- Volunteers
- 3 people
- Sponsor
- Rabin Medical Center
Type1diabetes, Hypoglycemia Unawareness
Hybrid Closed Loop Insulin Delivery System in Hypoglycemia
Can a type 1 diabetic adult avoid low glucoses and regain hypoglycemia awareness using a hybrid closed loop insulin delivery system? Involvement is 22 months (13 visits) and includes a 4-week Screening Phase and an 18-month…
- Conditions
- Type1diabetes, Hypoglycemia Unawareness, Nocturnal Hypoglycemia, Hypoglycemia Night
- Trial name
- Aim2 (NCT03215914)
- Testing
- MiniMed 670G system
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Diabetes
Comparison of Insulin Glargine and NPH Insulin at Night and at Hypoglycemia in Type 2 Diabetes
Long-acting insulin injected at bedtime may cause hypoglycemia (low blood sugar) in the night in patients with diabetes. The aims of the study are 1) to compare the dynamic characteristics of long-acting insulin analog glargine…
- Trial name
- ClampHOE901 (NCT00468364)
- Testing
- insulin glargine, NPH insulin
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- University of Giessen
Type 1 Diabetes
Use of Terbutaline or a Reduction in Basal Insulin in the Prevention of Nocturnal Hypoglycemia
The investigators hypothesize that the use of an oral dose of Terbutaline or a 20% basal reduction will be able to prevent nocturnal hypoglycemia after an afternoon exercise session.
- Trial name
- NCT00974051
- Testing
- Terbutaline, 20% basal insulin reduction, Control
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Colorado, Denver
Type 1 Diabetes, Hypoglycemia
Reduction of Nocturnal Hypoglycemia and Hyperglycemia in the Home Using Predictive Algorithms, Pump Suspension, and Insulin Dosing in Children and Young Adolescents
Objective: to gain experience in children and younger adolescents with in-home use of an algorithm that will dose insulin to minimize projected hyperglycemia overnight in addition to suspending the pump if hypoglycemia is…
- Conditions
- Type 1 Diabetes, Hypoglycemia, Hyperglycemia, Artificial Pancreas
- Trial name
- PHM3 (NCT02714972)
- Testing
- Hyperglycemia Minimization Algorithm
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- Jaeb Center for Health Research