Clinical trials: Hypomagnesemia
Hypomagnesemia, Critical Illness
Hypomagnesemia and Its Clinical Outcome
Magnesium is an essential electrolyte involved in numerous physiological processes, including maintaining cellular integrity, regulating muscle tone, supporting cardiovascular function, and modulating immune responses.
- Conditions
- Hypomagnesemia, Critical Illness, Intensive Care Unit (ICU) Patients, Scoring Systems
- Trial name
- Hypogamnesamia (NCT07089004)
- Testing
- No intervention (observational study)
- Where
- Bangladesh
- Volunteers
- 112 people
- Sponsor
- Bangladesh Bioscience Research Group
Metastatic Colorectal Cancer, Metastatic Head and Neck Cancer
Prophylaxis of Magnesium-rich Mineral Water to Prevent Hypomagnesemia Induced by an Anti-EGFR (OPTIMAG)
Anti-EGFR (Epidermal Growth Factor Receptor) therapies, namely cetuximab and panitumumab, have become standards in the management of metastatic colorectal and head and neck cancers.
- Trial name
- OPTIMAG (NCT03146338)
- Testing
- Magnesium-rich mineral water (Rozana)
- Where
- 12 sites in France
- Volunteers
- 106 people
- Sponsor
- Weprom
Hypomagnesemia, Coagulopathy
Association Between Hypomagnesemia and Coagulopathy in Sepsis
This study aimed to investigate the association between hypomagnesemia and coagulopathy in patients with sepsis, with a focus on evaluating whether low serum magnesium levels are independently linked to the development of…
- Conditions
- Hypomagnesemia, Coagulopathy, Sepsis
- Trial name
- NCT07576621
- Testing
- Serum magnesium concentration
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Hypomagnesemia in Type 2 Diabetic Patients
MLD10 for the Treatment of Hypomagnesemic Patients With Type 2 Diabetes Mellitus
To determine the effect of MLD10 (magnesium L-lactate dihydrate extended-release caplets) 10 mEq BID on serum magnesium in Type 2 diabetic patients with hypomagnesemia.
- Trial name
- NCT03567824
- Testing
- Magnesium L-lactate dihydrate
- Volunteers
- 200 people
- Sponsor
- Pharmalyte Solutions LLC
Hypomagnesemia
Magnesium Deficiency In Patients Hospitalized in Internal Medicine Wards
Hypomagnesemia is a common entity in the inpatient and outpatient setting. in previous retrospective study hypomagnesemic patients have higher mortality and longer hospitalization.
- Trial name
- NCT03088852
- Testing
- Magnesium Citrate 100 MG
- Where
- Israel
- Volunteers
- 330 people
- Sponsor
- Frieda Wolf
Renal Transplantation; Complication
Hypomagnesemia and Its Association With Calcineurin Inhibitors Use in Renal Transplant Recipients
To assess the prevalence and risk factors of hypomagnesemia and its association with calcineurin inhibitor use among Egyptian renal transplant recipients.
- Trial name
- NCT05352880
- Testing
- serum magnesium level, FEMg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Atrial Fibrillation (AF), Hypomagnesemia
Postoperative Incidence of Atrial Fibrillation Following Cardiac Surgery
Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery.
- Conditions
- Atrial Fibrillation (AF), Hypomagnesemia, Cardiac Surgery
- Trial name
- NCT06855550
- Where
- Colombia
- Volunteers
- 435 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Ovarian Carcinoma
Dietary Magnesium in Preventing Low Blood Magnesium Levels in Patients With Ovarian Cancer Receiving Carboplatin Chemotherapy
This trial studies how well a diet high in magnesium works in preventing low blood magnesium levels (hypomagnesemia) in patients with ovarian cancer receiving carboplatin chemotherapy.
- Trial name
- NCT04310826
- Testing
- Dietary Intervention, Media Intervention, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Primary Hypomagnesemia (Disorder)
Effect of Magnesium Sulfate Infusion Rate on Magnesium Retention in Critically Ill Patients
Hypomagnesemia (low magnesium) is an electrolyte imbalance commonly found in up to 65% of critically ill patients. Possible consequences of hypomagnesemia include neuromuscular and neurologic dysfunction, heart arrhythmias, and…
- Trial name
- NCT01426165
- Testing
- Magnesium Sulfate
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- CAMC Health System
Non-Insulin Dependent Diabetes Mellitus
Magnesium Treatment of Inflammation in Disorders of Glucose Homeostasis
In most diabetic patients where low blood magnesium levels occur the important depletion of cellular levels is usually not measured.
- Trial name
- MagInGlu (NCT01980459)
- Testing
- magnesium lactate
- Where
- Kuwait
- Volunteers
- 47 people
- Sponsor
- George Washington University
Diabetes Mellitus, High Blood Pressure
Magnesium and Metabolic Syndrome
Objective : to test the BP lowering-effect of oral magnesium supplementation, as magnesium chloride (MgCl2) solution, 2.5 g daily, in uncomplicated hypertensive type 2 diabetic subjects with decreased serum magnesium levels…
- Conditions
- Diabetes Mellitus, High Blood Pressure, Hypomagnesemia
- Trial name
- NCT00603499
- Testing
- Magnesium chloride
- Where
- Mexico
- Volunteers
- 85 people
- Sponsor
- Instituto Mexicano del Seguro Social
Acute Renal Failure, Dialysis Related Complication
Simplified Regional Citrate Anticoagulation Protocols for CVVH, CVVHDF and SLED: a Pilot Study
The aim of the study are: 1) To evaluate the occurrence of acid-base alterations and the incidence of hypophosphatemia during different modalities of Renal Replacement Terapy (RRT) in critically ill patients [CVVH, CVVHDF and…
- Conditions
- Acute Renal Failure, Dialysis Related Complication, Hypophosphatemia, Hypomagnesemia
- Trial name
- NCT03976440
- Testing
- Renal Replacement Therapy (RRT) start
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Parma
Hypomagnesemia, Kidney Transplantation
Magnesium Replacement and Hyperglycemia After Kidney Transplantation
The insulin receptor is dependent on magnesium and hypomagnesemia is associated with increased insulin resistance and decreased insulin secretion and action.
- Trial name
- NCT04382157
- Testing
- Mablet 360 mg
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Healthy
Magnesium Effects in Apheresis
This study will determine whether magnesium replacement during apheresis can decrease side effects that donors commonly experience.
- Trial name
- NCT00040235
- Testing
- magnesium
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Congestive Heart Failure, Hypovitaminosis D
Pilot Study: Hypovitaminosis D, Hyperparathyroidism and Hypomagnesemia in Patients With Congestive Heart Failure
People with heart failure may have low magnesium and low vitamin D levels. They may also have abnormally high levels of parathyroid hormones.
- Conditions
- Congestive Heart Failure, Hypovitaminosis D, Hyperparathyroidism
- Trial name
- NCT00887666
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- State University of New York - Downstate Medical Center
Proton Pump Inhibitor Adverse Reaction, Hypomagnesemia
Hypomagnesemia Associated With Proton-Pump Inhibitor Use
Use of proton pump inhibitors has been associated with hypomagnesemia. However, various case-control or prospective studies have found conflicting results with regards to proton pump inhibitors use and development of…
- Conditions
- Proton Pump Inhibitor Adverse Reaction, Hypomagnesemia, Arrhythmias, Cardiac, Seizures
- Trial name
- PPI_HypoMg (NCT04426994)
- Testing
- proton pump inhibitor use
- Where
- Singapore
- Volunteers
- 211,672 people
- Sponsor
- Changi General Hospital
Healthy Subjects, Hypomagnesemia
The Absorption of Magnesium Oxide Compared to Citrate in Healthy Subjects
The magnesium food content in the Western world is consistently reducing. Hypomagnesemia is common in hospitalized patients, especially in the elderly with coronary artery disease (CAD) and/or those with chronic heart failure.
- Trial name
- NCT00994006
- Testing
- Magnesium oxide, Magnesium citrate
- Where
- Israel
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Heart Failure With Preserved Ejection Fraction, Hypomagnesemia
Intracellular Magnesium and Heart Failure
Low magnesium levels are surprisingly common in those with a heart condition known as HFpEF, where the heart pumps well but is too rigid to fill properly with blood.
- Trial name
- NCT06353750
- Testing
- Magnesium supplement
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Hypomagnesemia
Magnesium Replacement Therapy to Prevent Acute Renal Failure in Critically Ill Patients
Acute renal failure (ARF) is a serious and common complication in hospitalized patients, occurring in more than 25% of intensive care unit (ICU) patients.
- Trial name
- NCT01700998
- Testing
- Magnesium
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Hypomagnesemia
Feasibility of Using an Integrated Consent Model to Compare Two Standard of Care Regimens for the Management of Hypomagnesemia From Anti-Cancer Therapies
Hypomagnesemia (hMg) is a common side effect of important anti-cancer therapies such as epidermal growth factor receptor inhibitors (EGFRIs) and platinum-containing anti-cancer drugs.
- Trial name
- OTT 15-03 (NCT02690012)
- Testing
- Magnesium Oxide, Magnesium Citrate
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Ottawa Hospital Research Institute