Clinical trials: Hypomotility
Colon Disease, Functional Constipation
Non-invasive Assessment of Colonic Motility
The current diagnostic process of colonic motility disorders often takes a long time and involves multiple invasive, painful and/or unnecessary diagnostic procedures.
- Conditions
- Colon Disease, Functional Constipation, Electroenterography, Slow Transit
- Trial name
- non-CoMoti (NCT04624334)
- Testing
- Elektro-Entero-Graphy procedure, EEnG Questionnaire, Gold Standard Questionnaire
- Where
- Netherlands
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Slow Transit Constipation
Effect of Fecal Microbiota Transplantation in Slow Transit Constipation
The purpose of this study is to evaluate the effect of fecal microbiota transplantation in adults with slow transit constipation.
- Trial name
- FMTSTC (NCT02301221)
- Testing
- Fecal microbiota transplantation (FMT), Vancomycin and bowel lavage
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jinling Hospital, China
Constipation, Slow Transit Constipation
Preoperative Fish Oil PN and Prognosis After Constipation Surgery
This is a prospective, multicenter, real-world observational study to evaluate the impact of perioperative parenteral nutrition (PN) with fish oil-containing lipid emulsion on outcomes in adult patients with constipation…
- Conditions
- Constipation, Slow Transit Constipation, Megacolon
- Trial name
- FOCP (NCT07470892)
- Testing
- Fish oil-containing total parenteral nutrition (PN)
- Volunteers
- 306 people
- Sponsor
- Qianfoshan Hospital
Esophageal Motility Disorders
Effect of Azithromycin on Oesophageal Hypomotility
Patients with difficulty in swallowing (dysphagia) or with reflux disease are frequently found to suffer from oesophageal hypomotility (weak contractions).
- Trial name
- NCT01448993
- Testing
- Azithromycin
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- JAFAR JAFARI
Gastroparesis, Slow Transit
Atmo SmartPill Comparison in Gastroparetic and Slow Transit Constipation Patients
This study will compare gastrointestinal transit time measured by the SmartPill and the Atmo gas capsule in patients with gastrointestinal motility disorders.
- Trial name
- NCT04977063
- Testing
- Atmo gas capsule, SmartPill
- Where
- 3 sites in Australia
- Volunteers
- 53 people
- Sponsor
- Atmo Biosciences Pty Ltd
Slow Transit Constipation
Using 16S rRNA Gene Sequencing Analysis Intestinal Microbiota in Constipation Patients
Constipation is a frequent, chronic gastroenterological problem that has many varied symptoms and thus has several clinical definitions.
- Trial name
- NCT02984969
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Slow Transit Constipation
Evaluating the Synergism of Soluble Dietary Fiber With Fecal Microbiota Transplantation in Slow Transit Constipation
The purpose of this study is to evaluate the synergism of Soluble Dietary Fiber with Fecal Microbiota Transplantation in Adult Patients with Slow Transit Constipation.
- Trial name
- NCT02291354
- Testing
- Pectin, Fecal microbiota transplantation (FMT)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Jinling Hospital, China
Constipation
Anti-peristaltic Ileo-sigmoid Anastomosis for the Treatment of Slow-transit Constipation:Therapeutic Evaluation
Purpose: To evaluate the curative effect of Laparoscope Sub-total Colectomy with Anti-peristaltic ileosigmoid anastomosis for the treatment of slow-transit constipation on the patients with STC.
- Trial name
- NCT02147574
- Testing
- Anti-peristaltic ileosigmoid anastomosis
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Anlong Zhu
Slow Transit, Constipation
Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation
Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum
- Trial name
- NCT04525248
- Testing
- Laparoscopic total colectomy + low resection of rectum, Laparoscopic total colectomy + High resection of rectum
- Volunteers
- 78 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Vitamine d Dosage in Slow Transit Time Constipation
Vitamine d Dosage and Constipation
Vitamine d dosage in important to define nutritional status and bone metabolism. For patients with intestinal disorders it is important to establish the intestinal absorptive function.
- Trial name
- NCT03096704
- Testing
- vitamine d dosage
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Constipation, Slow Transit Constipation
YQD Combined With Plant Lactobacillus for Slow Transit Constipation
Slow transit constipation (STC) is a common and difficult-to-treat subtype of chronic constipation, characterized by reduced colonic motility and delayed stool passage.
- Trial name
- YQD-LAC-STC (NCT07757061)
- Testing
- YQD (Yìqì Jiànpí Decoction), Plant-derived Lactobacillus, Mosapride Citrate
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First People's Hospital Of Lin'an District, Hangzhou
Fecal Incontinence and Constipation
Sacral Nerve Stimulation for Anal Incontinence and Bowel Control
Multicenter European study to evaluate efficacy and safety of sacral nerve stimulation with InterStim Therapy to treat fecal incontinence or constipation
- Trial name
- MDT-301 (NCT00200005)
- Testing
- Type: Implantable neurostimulator; InterStim
- Where
- 9 sites in United States, Austria and 6 more
- Volunteers
- 140 people
- Sponsor
- MedtronicNeuro
Hypomotility, Lumbar Spine Instability
Lumbar Manipulation in Lumbar Hypomobility
The purpose of the study is to compare the immediate effects of thrust versus non-thrust lumbar manipulation in individuals with lumbar hypo-mobility on lumbar range of motion and springing force tolerance.
- Trial name
- NCT04521244
- Testing
- Thrust joint lumbar manipulation, Lumbar mobilization
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Constipation, Surgery
Effectiveness and Safety of Sacral Neuromodulation in Patients With Idiopathic Slow-transit Constipation
Rationale: Previous reviews showed that the evidence regarding the effectiveness of sacral neuromodulation (SNM) in patients with therapy-resistant, idiopathic (slow-transit) constipation is of suboptimal quality.
- Trial name
- NCT02961465
- Testing
- Sacral Neuromodulation
- Where
- 2 sites in Netherlands
- Volunteers
- 23 people
- Sponsor
- Maastricht University Medical Center
Gastroparesis, Slow Transit Constipation
Comparison of the Atmo Motility Gas Capsule System to the Reference Standard
The study objective is to demonstrate the equivalence of the Atmo Motility Gas Capsule System with the predicate SmartPill in measuring gastric emptying time and colonic transit time through examination of device agreement.
- Conditions
- Gastroparesis, Slow Transit Constipation, IBS
- Trial name
- NCT05718505
- Testing
- Atmo Motility Gas Capsule System, SmartPill Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Atmo Biosciences Pty Ltd
Slow Transit Constipation
Freeze-dried vs Fresh Fecal Microbiota Transplantation in Patients With Slow Transit Constipation
The purpose of this study is to compare the effect of freeze-dried, capsulized FMT and fresh FMT in adults with slow transit constipation.
- Trial name
- NCT02676388
- Testing
- Freeze-dried, Capsulized FMT, Fresh FMT
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Jinling Hospital, China
Slow Transit Constipation
Efficacy and Safety of Fecal Microbiota Transplantation for Slow Transit Constipation
The purpose of this study is to evaluate the effect of fecal microbiota transplantation in adults with slow transit constipation.
- Trial name
- NCT02526849
- Testing
- Fecal microbiota transplantation (FMT), Conventional treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jinling Hospital, China
Constipation
Deep Needling at Zhongliao Point to Stimulate the Sacral Nerve for the Treatment of Slow Transit Constipation
Clinical Study on the Treatment of Colonic Slow Transit Constipation by Deep Acupuncture at Zhongliao Point Stimulating Sacral Nerve
- Trial name
- NCT06156995
- Testing
- Deep Acupuncture at Zhongliao Point to Stimulate Sacral Nerve, Oral Mosapride Tablets
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Guoliang Wu
Defecation Function, Quality of Life
Defecation Function and Quality of Life in the Patients Treated With Surgery for Slow Transit Constipation
Although surgical options for slow transit constipation (STC) have been proven to be a definite treatment, improvements in the associated defecation function and quality of life are rarely studied.
- Trial name
- NCT04304183
- Testing
- total colectomy, ileorectal anastomosis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Third Military Medical University
Slow Transit Constipation, Surgery
STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation
Total colectomy with ileorectal anastomosis is a traditional surgical option for slow transit constipation (STC). Subtotal colectomy with caecorectal anastomosis have been reported to be a potential alternative approach.
- Trial name
- NCT05352074
- Testing
- Total colectomy with ileorectal anastomosis, Subtotal colectomy with cecal-rectal anastomosis
- Where
- 14 sites in China
- Volunteers
- 252 people
- Sponsor
- Third Military Medical University