Clinical trials: Hypoparathyroidism Post-surgical
Hypoparathyroidism Post-surgical
Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism
The aim of this study is to investigate the effect of daily treatment with Indapamide for 14 days on urinary calcium excretion in patients with post surgical hypoparathyroidisme.
- Trial name
- HYPOCARE treat (NCT07034677)
- Testing
- Indapamide 1.5 MG SR
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Lars Rejnmark
Hypoparathyroidism Post-surgical
Teriparatide for Postsurgical Hypoparathyroidism
This study evaluated the effects of teriparatide (Forteo) on low calcium levels in the setting of thyroid surgery associated with low parathyroid hormone.
- Trial name
- NCT01171690
- Testing
- Teriparatide
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Hypoparathyroidism Postprocedural
Improving Safety in Pediatric Thyroidectomy by PTH Measurements
We implemented a previously reported algorithm based on intra-postoperative PTH measurements with selected cut-off values, both to predict post-thyroidectomy hypoparathyroid hypocalcemia, and to guide postsurgical management.
- Trial name
- NCT04690842
- Testing
- PTH measurements post-thyroidectomy (at 5 and 60 min post thyroid removal)
- Volunteers
- 66 people
- Sponsor
- Hospital de Niños R. Gutierrez de Buenos Aires
Hypoparathyroidism, Hypoparathyroidism Postprocedural
Evaluation of iMmune Function in Post-surgical and AuToimmune HYpoparathyroidism (EMPATHY)
This is an observational pilot study for the evaluation of immune function, infectious diseases, psychometric status and quality of life in patients with hypoparathyroidism compared to healthy controls.
- Conditions
- Hypoparathyroidism, Hypoparathyroidism Postprocedural, Hypoparathyroidism Due to Impaired Parathormone Secretion
- Trial name
- EMPATHY (NCT04059380)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Hypoparathyroidism Postprocedural
Autofluorescence vs Clinical Assessment of Parathyroid Glands During Thyroid Surgery
The purpose of the investigation is to study if the use of Fluobeam®-LX to identify parathyroid glands through autofluorescence during thyroid surgery, may reduce the risk of postoperative hypoparathyroidism, defined as low PTH…
- Trial name
- NCT04509011
- Testing
- Fluobeam® LX
- Where
- 5 sites in Austria, Norway and 2 more
- Volunteers
- 516 people
- Sponsor
- Region Skane
Hypoparathyroidism, Cardiovascular Complication
Cardiovascular, Renal, and Skeletal Complications in Patients With Post-Surgical Hypoparathyroidism
The aim of this observational study is to learn about long term effects to post surgical hypoparathyroidism. The main questions are: 1.
- Conditions
- Hypoparathyroidism, Cardiovascular Complication, Fractures, Bone, Renal Disease
- Trial name
- CAREHYPO (NCT06419270)
- Testing
- Observation
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism
PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery"
This study aims to investigate whether an earlier measurement of parathyroid hormone can reduce the number of patients who develop symptomatic hypoparathyroidism.
- Conditions
- Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism, Hypoparathyroidism Post-surgical
- Trial name
- PRESSPAR (NCT07491601)
- Testing
- Active vitamin D, Calcium
- Where
- Germany
- Volunteers
- 336 people
- Sponsor
- Nicolas Schlegel
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Hypoparathyroidism, Hypoparathyroidism Postprocedural
Parathyroid Allotransplant for Treatment of Hypoparathyroidism
This study is being done to see if transplanting parathyroid tissue into the forearm will help hypo-parathyroid patients achieve parathyroid hormone (PTH) levels that would help normalize their serum calcium and phosphorus…
- Conditions
- Hypoparathyroidism, Hypoparathyroidism Postprocedural, Hypoparathyroidism Post-surgical
- Trial name
- PATTH (NCT06961071)
- Testing
- Parathyroid Allotransplant
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Peter Stock
Hypoparathyroidism Post-surgical, Quality of Life
Effects of Total Thyroid Removal on Parathyroid Function and Quality of Life
Postoperative hypoparathyroidism (hypoPT) is the most frequent complication after total thyroidectomy (TT). It is caused by impaired parathyroid function, leading to low calcium levels, patient discomfort, reduced quality of life…
- Trial name
- NCT07381998
- Testing
- high-dose calcium (400 mg x 4), vitamin D (19 mikg x 4), and active vitamin D supplementation (2 mikg x 2), Ommit routine blood test post operative day 1
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Aarhus University Hospital
Hypoparathyroidism Postprocedural, Hypocalcemia
Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
The objective of this ongoing randomized controlled trial is to examine whether the use of intra-operative NIR(near infrared) camera can reduce the number of patients who experience transient or persistent hypoparathyroidism…
- Conditions
- Hypoparathyroidism Postprocedural, Hypocalcemia, Surgery--Complications
- Trial name
- NCT04193332
- Testing
- NIR optical imaging camera
- Where
- 2 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-Surgical Hypoparathyroidism
Risk Factors for Hypoparathyroidism Following Thyroidectomy
The goal of this observational study is to identify the risk factors for post-thyroidectomy hypoparathyroidism in Estonia and to determine whether the magnesium level plays a significant role in the development of…
- Trial name
- NCT07582562
- Where
- 2 sites in Estonia
- Volunteers
- 300 people
- Sponsor
- Tartu University Hospital
Hypocalcemia, Total Thyroidectomy
Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy
The intensity of parathyroid fluorescence that occurs after intravenous injection of indocyanine green during the performance of a total thyroidectomy correlates with postoperative parathyroid function and could be used as a…
- Conditions
- Hypocalcemia, Total Thyroidectomy, Hypoparathyroidism Postprocedural
- Trial name
- NCT04012476
- Testing
- Indocyanine Green
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Son Espases
Hypocalcemia, Parathyroid
Comparing PTeye-assisted Versus Conventional Total Thyroidectomy
This is a prospective, single-blinded, randomized controlled trial to evaluate whether PTeye™ can reduce post-operative hypoparathyroidism (PH).
- Conditions
- Hypocalcemia, Parathyroid, Hypoparathyroidism Post-surgical, Total Thyroidectomy
- Trial name
- NCT07416149
- Testing
- PTeye™ parathyroid detection system
- Where
- Hong Kong
- Volunteers
- 210 people
- Sponsor
- The University of Hong Kong
Post-Surgical Hypoparathyroidism
PTH-independent Effects of Encaleret
Background: Parathyroid glands in the neck make a hormone that keeps blood calcium levels stable. Sometimes these glands are damaged or removed during neck surgery.
- Trial name
- NCT05735015
- Testing
- encaleret
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)