Clinical trials: Hypoparathyroidism Postprocedural
Hypoparathyroidism, Hypoparathyroidism Postprocedural
Parathyroid Allotransplant for Treatment of Hypoparathyroidism
This study is being done to see if transplanting parathyroid tissue into the forearm will help hypo-parathyroid patients achieve parathyroid hormone (PTH) levels that would help normalize their serum calcium and phosphorus…
- Conditions
- Hypoparathyroidism, Hypoparathyroidism Postprocedural, Hypoparathyroidism Post-surgical
- Trial name
- PATTH (NCT06961071)
- Testing
- Parathyroid Allotransplant
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Peter Stock
Hypoparathyroidism Postprocedural
Near-infrared Imaging Techniques for Identifying and Preserving Viable Parathyroid Glands During Thyroidectomy
The parathyroid glands and their blood vessels are notoriously difficult to visualize and may therefore be unintentionally and irrevocably damaged during thyroid surgery.
- Trial name
- NCT05130476
- Testing
- Near-infrared-induced autofluorescence and indocyanine green near-infrared angiography
- Where
- Denmark
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hypoparathyroidism Postprocedural
Autofluorescence vs Clinical Assessment of Parathyroid Glands During Thyroid Surgery
The purpose of the investigation is to study if the use of Fluobeam®-LX to identify parathyroid glands through autofluorescence during thyroid surgery, may reduce the risk of postoperative hypoparathyroidism, defined as low PTH…
- Trial name
- NCT04509011
- Testing
- Fluobeam® LX
- Where
- 5 sites in Austria, Norway and 2 more
- Volunteers
- 516 people
- Sponsor
- Region Skane
Thyroidectomy, Hypoparathyroidism Postprocedural
Validation of a Hypoparathyroidism Self-questionnaire
The aim of this study is to evaluate, for patients with post-thyroidectomy hypoparathyroidism (HoPT), the severity of their HoPT and to validate clinical scores from a self-administered questionnaire related to this disease…
- Trial name
- SEV-HYPOPARA (NCT05642741)
- Testing
- Response to medical and research questionnaires
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Nantes University Hospital
Hypoparathyroidism Postprocedural, Quality of Life
Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy Hypoparathyroidism
This study aims to compare two different protocols commonly used in the management of post thyroidectomy hypoparathyroidism : PTH based calcium repletion and empiric repletion.
- Trial name
- NCT03249012
- Testing
- Empiric use of Calcium Carbonate and Calcitriol, PTH based Calcium Carbonate and Calcitriol repletion
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- CHU de Quebec-Universite Laval
Hypoparathyroidism Postprocedural
Parathyroid Allotransplant for Severe Refractory Hypoparathyroidism
Hypoparathyroidism following thyroid surgery presents significant challenges, often leading to debilitating symptoms and reduced quality of life despite conventional treatment.
- Trial name
- NCT06499246
- Testing
- Donor Parathyroid
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Karen Devon
Thyroid Disease, Hypoparathyroidism Postprocedural
Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy
Hypoparathyroidism (and the resulting hypocalcemia) remains the most common morbidity after a total thyroidectomy. The identification and preservation of parathyroid glands during neck surgery has always been challenging but is…
- Trial name
- NCT05117853
- Testing
- Autofluorescent detection + Injection of indocyanine green, Gold standard of visual identification and evaluation of viability of the parathyroid glands.
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Onze Lieve Vrouw Hospital
Hypoparathyroidism, Hypoparathyroidism Postprocedural
Evaluation of iMmune Function in Post-surgical and AuToimmune HYpoparathyroidism (EMPATHY)
This is an observational pilot study for the evaluation of immune function, infectious diseases, psychometric status and quality of life in patients with hypoparathyroidism compared to healthy controls.
- Conditions
- Hypoparathyroidism, Hypoparathyroidism Postprocedural, Hypoparathyroidism Due to Impaired Parathormone Secretion
- Trial name
- EMPATHY (NCT04059380)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Hypoparathyroidism Postprocedural, Hypocalcemia
Near Infrared (NIR) Autofluorescence Image-guided Thyroid Surgery
The objective of this ongoing randomized controlled trial is to examine whether the use of intra-operative NIR(near infrared) camera can reduce the number of patients who experience transient or persistent hypoparathyroidism…
- Conditions
- Hypoparathyroidism Postprocedural, Hypocalcemia, Surgery--Complications
- Trial name
- NCT04193332
- Testing
- NIR optical imaging camera
- Where
- 2 sites in Denmark
- Volunteers
- 214 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hypocalcemia, Vitamin D Deficiency
The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients.
Glucocorticoids are well known for their analgesic, anti-inflammatory, immunomodulatory and anti-emetic effects. Recovery time after thyroid surgery may depend on several factors, such as postoperative pain, nausea and vomiting…
- Conditions
- Hypocalcemia, Vitamin D Deficiency, Postoperative Complications, Postoperative Nausea
- Trial name
- Dexa (NCT04412694)
- Testing
- Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland)., Preoparative blood laboratory tests, Postoperative laboratory blood tests at 6 hour
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Hypoparathyroidism Postprocedural
Study on the Effects of Hypoparathyroidism on Post-thyroidectomy Health-related Quality of Life (QoL-hPTP)
Our study will evaluate the health related quality of life (HRQoL) after a thyroidectomy and the relevance of postoperative hypoparathyroidism.
- Trial name
- QoL-hPTP (NCT04604808)
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Hypoparathyroidism Postprocedural
Improving Safety in Pediatric Thyroidectomy by PTH Measurements
We implemented a previously reported algorithm based on intra-postoperative PTH measurements with selected cut-off values, both to predict post-thyroidectomy hypoparathyroid hypocalcemia, and to guide postsurgical management.
- Trial name
- NCT04690842
- Testing
- PTH measurements post-thyroidectomy (at 5 and 60 min post thyroid removal)
- Volunteers
- 66 people
- Sponsor
- Hospital de Niños R. Gutierrez de Buenos Aires
Hypoparathyroidism Postprocedural
Changes in Circulating Sclerostin Levels During Acute Postsurgical Hypoparathyroidism
To investigate changes in sclerostin levels following acute post-thyroidectomy hypoparathyroidism
- Trial name
- NCT04146259
- Testing
- calcium carbonate and alphacalcidol
- Where
- Greece
- Volunteers
- 109 people
- Sponsor
- University of Athens
Hypocalcemia, Total Thyroidectomy
Determination of Parathyroid Function by Fluorescence With Indocyanine Green (ICG) After Total Thyroidectomy
The intensity of parathyroid fluorescence that occurs after intravenous injection of indocyanine green during the performance of a total thyroidectomy correlates with postoperative parathyroid function and could be used as a…
- Conditions
- Hypocalcemia, Total Thyroidectomy, Hypoparathyroidism Postprocedural
- Trial name
- NCT04012476
- Testing
- Indocyanine Green
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Son Espases
Thyroid Cancer, Parathyroid; Absent
Intra-operative Rapid Identification of Lymph Node and Parathyroid
During surgery, a fine needle puncture was proceeded when suspicious nodes was found by clinician. Repeat the punction for 2-3 times from different orientation and then, Diff-quik staining or PTH immunochromatographic assay were…
- Conditions
- Thyroid Cancer, Parathyroid; Absent, Hypocalcemia, Hypoparathyroidism Postprocedural
- Trial name
- NCT03268785
- Testing
- Intraoperative identification method
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital