Clinical trials: Hypotension
Hemodialysis, Hypotension
Safety of Dialysate Sodium Individualization in Hemodialysis Patients With Intradialytic Hypotension
Low blood pressure (hypotension) during dialysis afflicts approximately 25% of hemodialysis patients. In this pilot study, we will evaluate the safety and effects of individualizing the sodium concentration in the dialysate…
- Trial name
- NCT00237783
- Testing
- dialysate sodium (140 mmol/L), individualized dialysate sodium
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Yale University
Hypotension, Hypovolemia
Hemodynamic Assessment During Spinal Anesthesia Using Transthoracic Echocardiography'
Rationale: Spinal anesthesia is a safe, frequently used anesthetic technique. The main side effect of spinal anesthesia is hypotension, occuring in up to 85 % of selected cases.
- Trial name
- SATE (NCT02315937)
- Testing
- transthoracic echocardiography
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Shock, Septic
Pilot Study: Echocardiographic and Hemodynamic Effects of Esmolol in Septic Shock Patients
After initial hemodynamic stabilization, 36 septic shock patients with heart rate > of 90 bpm and requiring norepinephrine to maintain mean arterial pressure (MAP) more than 65 mmHg will be randomised into two groups, esmolol…
- Trial name
- NCT02842983
- Testing
- Esmolol
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Peking Union Medical College Hospital
Hypotension
Haemodynamic Response to General Anaesthesia in Healthy Orthopaedic Patients
Continuous cardiovascular monitoring as part of management of high-risk surgical patients is widely practiced, however its role in low-risk surgical patients is unclear.
- Trial name
- HRespToAS (NCT02834000)
- Testing
- LiDCO rapid™ CNAP monitoring
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Hypotension
Hemodynamic Impact of Hyperbaric Versus Isobaric for Spinal Anesthesia During Cesarean Delivery
The purpose of this study is to compare the frequency of hypotension between hyperbaric anesthetics and isobaric anesthetics during cesarean section and determine whether continuous infusion of phenylephrine is effective in…
- Trial name
- NCT02802683
- Testing
- Bupivacaine, Levobupivacaine, Phenylephrine
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Diuresis, Bladder Retention Volume
Effect of Preload on Bladder Retention Volume During Spinal Anesthesia
The purpose of this study is to assess the influence of different fluid infusions on the quantity of bladder retention after spinal anesthesia.
- Conditions
- Diuresis, Bladder Retention Volume, Hypotension
- Trial name
- NCT00550186
- Testing
- Ringers Lactate, HaemoHES 6%
- Where
- Netherlands
- Volunteers
- 144 people
- Sponsor
- Rijnstate Hospital
Brain Injuries, Hypotension, Orthostatic
Study of Pulse Pressure During Tilttable and Erigo® in Adult Patients With Acquired Brain Injury
The purpose of this study is to determine if the pulse pressure changes are different whether patients are training in a traditional tilt table as compared to a robotic assisted tilt table, which induces leg movement.
- Conditions
- Brain Injuries, Hypotension, Orthostatic, Syncope
- Trial name
- NCT02700399
- Testing
- Erigo® Hocoma, Traditional tilt table from Rehab-Care
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- University of Aarhus
Ascites, Hypotension
The Role of Intravenous Albumin Replacement During Abdominal Paracentesis in Patients With Malignancy Related Ascites
Aims: To compare the rates of hypotension in patients with malignancy-related ascites undergoing abdominal paracentesis with and without prophylactic intravenous albumin infusion Methodology: Patients with symptomatic ascites…
- Trial name
- NCT02811406
- Testing
- Receives IV albumin infusion, Do not receive IV albumin infusion
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Hypotension and Shock
A Comparison of Crystalloid Alone Versus Crystalloid Plus Colloid in Shock Resuscitation
Fluid resuscitation is the most effective treatment of shock. Isotonic crystalloid solution is the current recommended initial fluid resuscitation.
- Trial name
- NCT02782819
- Testing
- Isotonic crystalloid solution resuscitation, Colloid solution resuscitation
- Where
- Thailand
- Volunteers
- 320 people
- Sponsor
- Mahidol University
Hypotension
Predictability of the Pulse Pressure Variation (PPV) During Spontaneous Ventilation on the Incidence of Hypotension During Induction of Anesthesia
The purpose of this study is to find out the predictability of the pulse pressure variation during spontaneous ventilation on the incidence of hypotension during induction of anesthesia.
- Trial name
- NCT02208570
- Testing
- PPV>14%, Volume loading, PPV<14%
- Where
- South Korea
- Volunteers
- 172 people
- Sponsor
- Seoul National University Hospital
Hypotension, Orthostatic
Orthostatic Hypotension in Rehabilitation Patients
The purpose of this study is to determine the prevalence and clinical course of orthostatic hypotension (OH) on a rehabilitation and nursing home unit during their inpatient stay and to initiate a standardized, interdisciplinary…
- Trial name
- NCT00117585
- Testing
- Treatment Phase 1, Treatment Phase 2, Treatment Phase 3
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- VA Office of Research and Development
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Arterial Hypotension
Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates
The purpose of this study is to examine the effects of Dobutamine as compared to Dopamine in term and preterm neonates with arterial hypotension on cerebral and renal oxygenation, fractional tissue oxygen extraction, mean…
- Trial name
- NCT01427686
- Testing
- Dobutamine, Dopamine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Ulm
Circulatory Collapse, Circulatory Failure
Suspension Syndrome
Suspension syndrome refers to a potentially life-threatening condition that can occur in unconscious persons after prolonged suspension in a harness.
- Conditions
- Circulatory Collapse, Circulatory Failure, Syncope, Vasovagal, Neurally-Mediated, Orthostatic Hypotension
- Trial name
- NCT02726776
- Testing
- Suspension in a harness, Climbing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Autonomic Nervous System Diseases, Baroreflex Failure
Effects of Water and Glucose Drinks on Cardiovascular Function in Subjects With and Without Postprandial Hypotension
To determine whether the changes in blood pressure (BP) which occur following meals in normal people and patients who have substantial falls in BP after a meal postprandial hypotension (PPH)) are associated with changes in…
- Conditions
- Autonomic Nervous System Diseases, Baroreflex Failure, Blood Pressure, Hypotension
- Trial name
- NCT02713412
- Testing
- Glucose, Water
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Royal Adelaide Hospital
Maternal Hypotension, Anesthesia
Low Dose Spinal Anesthesia in Cesarean Surgery
Anesthesia for cesarean section requires special importance because it may affect both mother and the baby. To avoid maternal hypotension related to spinal anesthesia must be the primary objective during anesthesia.
- Trial name
- NCT02563795
- Testing
- Bupivacaine, Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara University
Hypotension
Prevention of Maternal Hypotension During Elective Caesarean Section Performed With Spinal Anaesthesia, Through Intermittent Pneumatic Compression System in the Lower Extremities
The hypotension defined as 20 % less than the basal SBP (systolic blood pressure)and / or an absolute value <90-100 mmHg, he presents an incident of 80-85% after an anesthesia intradural in the pregnant women, fact that worries…
- Trial name
- NCT01891175
- Testing
- Elective caesarean section under spinal anaesthesia.
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Intradialytic Hypotension
A Preliminary Randomized Study of Tianjiu (Auto-moxibustion) Effects in Patients With Intradialytic Hypotension
Intradialytic hypotension (IDH) is a most frequent complication of hemodialysis (HD) and may contribute to cardiovascular events and high mortality.
- Trial name
- NCT02210377
- Testing
- Tianjiu
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Chang Gung Memorial Hospital
Hypotension
Prediction of Hypotension During Beach Chair Position Using Pleth Variability Index
The beach chair position for shoulder operation induces hypotension during general anesthesia. Hypotension is induced by decreased preload and contractility due to anesthesia.
- Trial name
- NCT02527538
- Testing
- Pleth
- Where
- South Korea
- Volunteers
- 57 people
- Sponsor
- Chung-Ang University Hospital
Symptomatic Neurogenic Orthostatic Hypotension, Parkinson's Disease
A Clinical Study of Patients With Symptomatic NOH to Assess Sustained Effects of Droxidopa Therapy
Evaluate the clinical efficacy and safety of droxidopa versus placebo over a 17 week (maximum) treatment period in patients with symptomatic NOH.
- Conditions
- Symptomatic Neurogenic Orthostatic Hypotension, Parkinson's Disease, Multiple Systems Atrophy, Pure Autonomic Failure
- Trial name
- NCT01927055
- Testing
- Droxidopa
- Where
- 3 sites in United States
- Volunteers
- 61 people
- Sponsor
- Chelsea Therapeutics