Clinical trials: Hypotension After Spinal Anesthesia
Maternal Hypotension
Norepinephrine Consumption After Prophylactic Ondansetron
This study evaluates the effect of prophylactic ondansetron on the incidence of spinal hypotension and vasopressor consumption in caesarean section patients using norepinephrine treatment.
- Trial name
- NCT02928601
- Testing
- Ondansetron, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Anesthesia, Adverse Effect
Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects.
- Conditions
- Anesthesia, Adverse Effect, Hypotension, Cesarean Section Complications
- Trial name
- NCT03706755
- Testing
- Norepinephrine: 1mcg/kg, Norepinephrine 0,5mcg/kg
- Where
- Tunisia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Post Spinal Anaesthesia Hypotension, Inferior Vena Cava Collapsibility Index
Inferior Vena Cava Collapsibility Index Assessment in Predicting Post Spinal Anaesthesia Hypotension in Patients Undergoing Arthroscopic Knee Surgeries.
The aim of this study was to evaluate the role of inferior vena cava collapsibility index assessment in predicting post spinal anaesthesia hypotension in patients undergoing arthroscopic knee surgeries.
- Trial name
- NCT06767033
- Testing
- Ultrasound Guided Inferior Vena Cava Collapsibility Index Assessment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy Participants
Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.
Tranexamic acid is a well-established treatment for post-partum hemorrhage. This study aims to examine the effect of tranexamic acid administration rates on blood pressure changes over 1 minute compared to 10 minutes in healthy…
- Trial name
- RateTXA (NCT06356948)
- Testing
- Tranexamic Acid (TXA)
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Post Spinal Hypotension
Perfusion Index vs Positional Hemodynamic Changes to Predict Hypotension After Spinal Anaesthesia in Caesarean Section
Comparative Study between the Perfusion Index and Positional Haemodynamic Changes for Prediction of Hypotension after Spinal Anaesthesia in Caesarean Section
- Trial name
- NCT05587153
- Testing
- perfusion index in all parturient recruited for the study
- Where
- 2 sites in Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cesarean Section
Predictability of Preoperative Carotid Artery Corrected Flow Time for Hypotension After Spinal Anesthesia in Patients Undergoing Cesarean Section
The purpose of this study was to investigate the incidence of hypotension after spinal anesthesia in patients undergoing cesarean section as predicted by preoperative carotid artery corrected flow time measured by Doppler…
- Trial name
- NCT03631329
- Testing
- Doppler sonographic measurement
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Anesthesia; Adverse Effect, Spinal and Epidural
Prophylaxis Ephedrine or Ondansetron Prevents Hypotension After Spinal Anesthesia for Cesarean Section
Maternal hypotension after spinal anesthesia in parturients undergoing cesarean section is a very common problem leading to several complications to both patients and their babies.
- Trial name
- NCT02194192
- Testing
- Ondansetron, Ephedrine
- Where
- Thailand
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital
Post-spinal Anesthesia Hypotension
Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension
The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.
- Trial name
- NCT04780139
- Testing
- Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension
Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study
Spinal anesthesia is the most common anesthetic technique for elective Cesarean delivery (CD), but the most frequent unwanted side effect is hypotension, which can cause nausea and vomiting, as well as effects on the fetus.
- Trial name
- NCT02654847
- Testing
- Norepinephrine, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anesthesia, Spinal
Caval-aorta Index and Perfusion Index on Predict Hypotension After Spinal Anaesthesia in Elderly
The aim of our study was to predict hypotension by using caval aorta index and perfusion index in elderly patients who may develop hypotension after spinal anesthesia.
- Trial name
- NCT06479512
- Testing
- ultrasonography to measure the index of the caval aorta and non-invasive pulse oximetry for perfusion index
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
HYPOTENSION AFTER SPINAL ANESTHESIA,IN PREGNANCY
EFFECT OF DIFFERENT NOREPINPHRINE APPLICATION METHODS IN CAESARIANES ON HYPOTENSION AFTER SPINAL ANESTHESIA
There are previous studies in which norepinephrine was administered only as a prophylactic or only infusion to prevent hypotension after spinal anesthesia in cesarean sections.
- Trial name
- NCT04951167
- Testing
- Norepinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anesthesia, Spinal
Prediction of Hypotension Using Perfusion Index Following Spinal Anesthesia
It is aimed to investigate whether the perfusion index (PI) can predict hypotension after spinal anesthesia in elderly patients as much as in non-elderly patients.
- Trial name
- NCT06427382
- Testing
- Perfusion index
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Head-Down Tilt Following Spinal Anesthesia
Cephalic Spread of Block With Head Down Tilt in Spinal Anaesthesia - A Randomised Controlled Study
Subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgeries. Several factors determine the spread of local anaesthetic solutions in CSF.
- Trial name
- NCT03491319
- Testing
- Group X - head low tilt, Group Y - head low tilt, Group C - neutral
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nitte University
Post Spinal Anesthesia Hypotension
Preoperative Oral Midodrine Versus Intraoperative Intravenous Norepinephrine in Preventing Post-spinal Anesthesia Hypotension in Cesarean Section: A Prospective Double-blind Randomized Clinical Trial
Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient, Prevention of this spinal anaesthesia induced…
- Trial name
- NCT06213935
- Testing
- Norepinephrine, Midodrine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Maternal Hypotension Syndrome, Cesarean
Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section
Spinal anesthesia is still the gold standard anesthetic method for elective and urgent cesarean section, the post spinal hypotension remains the most frequent complication of this procedure and is still responsible of…
- Trial name
- NCT03719625
- Testing
- Ephedrine, Norepinephrine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Leg Elevation for Prevention of Post Spinal Hypotension in Cesarean Section
Prospective trial including full term parturients scheduled for a cesarean section under spinal anesthesia. patients are being randomly assigned into 2 groups: LE group: will be positioned in 15° left tilt with leg elevation with…
- Trial name
- NCT03488277
- Testing
- leg elevation
- Where
- Tunisia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Cesarean Section, Spinal Anesthesia
Predictability of ANI (Analgesia Nociception Index) for Spinal Hypotension
Spinal anesthesia is widely accepted as the anesthetic method of choice for Cesarean section. However, the incidence of spinal hypotension is 50-70%, and the decrease in blood pressure is often rapid and severe.
- Trial name
- NCT06327165
- Testing
- observation
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hypotenstion, Cesarean Resection
Norepinephrine vs. Phenylephrine for Spinal Hypotension in Cesarean Section
This clinical trial was conducted to compare the effectiveness and safety of two medications-norepinephrine and phenylephrine-in treating low blood pressure (hypotension) that often occurs during spinal anesthesia for cesarean…
- Conditions
- Hypotenstion, Cesarean Resection, Anesthesia Spinal, Pregnancy Complications
- Trial name
- Norepinephrine (NCT07153601)
- Testing
- Norepinephrine 4mcg, Phenylephrine 50 mcg
- Where
- Indonesia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universitas Sumatera Utara