Clinical trials: Hypotension During Cesarean Delivery
Intraoperative Hypotension
Do Compression Stockings Used During Cesarean Sections Affect Intraoperative Hypotension and Nausea?
The present study aimed to determine the effects of compression stockings used during cesarean section on intraoperative hypotension.
- Trial name
- NCT06707428
- Testing
- compression stockings
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Anesthesia, Spinal
Norepinephrine vs. Phenylephrine for Hypotension in Low-Dose Spinal Anesthesia for Cesarean Delivery
This clinical trial was conducted to compare the effectiveness and safety of two medications, norepinephrine and phenylephrine, in preventing hypotension during low-dose spinal anesthesia for cesarean delivery (CD).
- Conditions
- Anesthesia, Spinal, Cesarean Section, Hypotension, Controlled
- Trial name
- NORPHE-CD (NCT07327320)
- Testing
- Norepinephrine, Phenylephrine
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tam Anh Research Institute
Cesarean Section, Cardiac Output
Best Regimen for Phenylephrine Administration During Cesarean Section
During Cesarean delivery, phenylephrine is used to maintain the patient's blood pressure. Low blood pressure is the most common side effect of the spinal medication used to anesthetize the patient prior to the start of surgery.
- Conditions
- Cesarean Section, Cardiac Output, Hypotension
- Trial name
- NCT00996190
- Testing
- Phenylephrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Pregnancy, Cesarean Delivery
Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia
Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).
- Conditions
- Pregnancy, Cesarean Delivery, Spinal Anesthesia Induced Hypotension, Cardiac Output Measurement
- Trial name
- NCT06654687
- Testing
- Transthoracic Echocardiography, Ringer lactate 1000 ml, Albumin
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Sameh Fathy
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean Section
This randomized controlled trial aims to compare the effectiveness of different doses of ephedrine infusion in preventing maternal hypotension following spinal anesthesia in parturients undergoing cesarean sections.
- Trial name
- NCT06668337
- Testing
- Ephedrine
- Where
- Nepal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Preeclampsia, Hypotension
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Hypotension remains a common clinical problem after induction of spinal anesthesia for cesarean delivery. Maternal hypotension has been associated with considerable morbidity (maternal nausea and vomiting and fetal/neonatal…
- Trial name
- NCT00458003
- Testing
- Ephedrine, Phenylephrine
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Hypotension
Manging Post Spinal Hypotension During Elective Cesarean Section
Spinal anesthesia is the gold standard technique for elective cesarean section. It helps to avoid risks regarding airway management and provides effective neuraxial postoperative analgesia, enabling quicker maternal recovery.
- Trial name
- EpiEph (NCT03704909)
- Testing
- Adrenaline, Ephedrine
- Where
- Tunisia
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Ben marzouk Sofiene
Healthy
Hemodynamic Measurements During Cesarean Section With Spinal Anesthesia
The purpose of this study is to determine the effect of low dose versus standard dose spinal anesthesia with and without intravenous phenylephrine-infusion on blood pressure, cardiac output and systemic vascular resistance.
- Trial name
- NCT00199784
- Testing
- Phenylephrine
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hypotension, Anesthesia
Intramuscular Phenylephrine HCL for Prevention of Spinal Anesthesia Induced Hypotension
Background: Spinal anesthesia (SA) is preferred over general anesthesia in Cesarean section (CS) due to its better safety profile but SA induced hypotension remains a big challenge for the clinical Anesthetist.
- Trial name
- NCT05348980
- Testing
- Phenylephrine Hydrochloride 4 mg, Phenylephrine Hydrochloride 8 mg
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Hypotension Drug-Induced
Effectiveness of Phenylefrine in Prevention of Hypotension During Spinal Anesthesia for Cesarean Delivery
Hypotension in patients who are taken to surgery, is a very frequent complication, when the spinal anesthetical technique is used, associating this with significant adverse effects that can lead to morbidity specially in the…
- Trial name
- NCT02979405
- Testing
- Phenylephrine
- Where
- Colombia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universidad Industrial de Santander
Severty of Hpotention
Comparing Sitting Versus Lateral Position During Spinal Anesthesia on the Severity of Hypotension:
This study aimed to assess the effect of sitting and lateral positions on the severity of hypotension during the initiation of spinal anesthesia in elective cesarean section. There will be Sitting and Lateral groups in the study.
- Trial name
- NCT06149572
- Testing
- lateral position procedure, sitting position porocedure
- Where
- Ethiopia
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Wollo University
Hypotension
Prevention of Maternal Hypotension During Elective Caesarean Section Performed With Spinal Anaesthesia, Through Intermittent Pneumatic Compression System in the Lower Extremities
The hypotension defined as 20 % less than the basal SBP (systolic blood pressure)and / or an absolute value <90-100 mmHg, he presents an incident of 80-85% after an anesthesia intradural in the pregnant women, fact that worries…
- Trial name
- NCT01891175
- Testing
- Elective caesarean section under spinal anaesthesia.
- Where
- 3 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Anesthesia; Adverse Effect, Spinal and Epidural, Hypotension
Colloid Preload Versus Colloid Coload During Cesarean Deliveries
The investigators aimed to compare the methods colloid preloading and colloid coloading in terms of the incidence of maternal hypotension and impacts on neonatal outcomes.
- Trial name
- NCT02393196
- Testing
- hydroxyethyl starch (% 6 HES 130/0.4) (Voluven®), hydroxyethyl starch (%6 HES 130/0.4) (Voluven®)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sifa University
Hypotension
Closed-loop Double-vasopressor Automated System to Treat Hypotension During Spinal Anaesthesia for Caesarean Section
Hypotension occurs commonly during spinal anesthesia for caesarean section with maternal and fetal adverse effects. The investigators developed a double-vasopressor automated system incorporating continuous non-invasive arterial…
- Trial name
- NCT04025918
- Testing
- Vasopressor automated delivery system, Phenylephrine, Ephedrine
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Hypotension, Vasopressors
Norepinephrine Versus Ephedrine in Treatment of Hypotension During Spinal Anesthesia for Caesarean Section
Prospective, randomized study, including full term parturients scheduled for caesarean section under spinal anesthesia. Spinal anesthesia was performed in sitting position with a 25 G spinal needle and all patients received 15…
- Conditions
- Hypotension, Vasopressors, Cesarean Section Complications, Anesthesia Complication
- Trial name
- NCT03163407
- Testing
- Norepinephrine, Ephedrine
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Obstetric Anesthesia Problems
Preloading to Prevent Hypotension During Cesarean Section
Whether the usage of non-invasive arterial blood pressure monitor to guide fluid therapy in caesarean section can effectively reduce the incidence of hypotension and fetal complications.
- Trial name
- NCT03013140
- Testing
- Fluid therapy, Spinal anaesthesia
- Where
- Taiwan
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myocardial Ischemia, Hypotension
Cardiac Effects of Oxytocin Administrated During Cesarean Section, Signs of Myocardial Ischemia
Oxytocin has cardio vascular effects as hypotension, tachycardia and possibly coronary spasm. The uterotonic effect of the drug is used during cesarean section, to minimize blood loss.ECG changes suggestive of cardiac ischemia…
- Conditions
- Myocardial Ischemia, Hypotension, Bloodloss
- Trial name
- NCT00777166
- Testing
- oxytocin
- Where
- Sweden
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Spinal Anesthesia, Pregnancy
Ephedrine vs Phenylephrine - ECG Changes
ECG changes during caesarean section are common. Incidence of ST depression on the ECG is up to 81% in some studies. Although this may indicate inadequate oxygen supply to the heart muscle (myocardial ischaemia) many other…
- Trial name
- NCT01243970
- Testing
- Phenylephrine, Ephedrine
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Anxiety, Hypotension
Impact of Music on Satisfaction, Anxiety, and Hemodynamics During Spinal Anesthesia for Cesarean Delivery
The aim of this study is to evaluate the effect of perioperative music on maternal anxiety, hemodynamic response to spinal anesthesia, postoperative pain medication requirement, and overall maternal satisfaction.
- Trial name
- NCT02732964
- Testing
- Pandora Music, Mozart Music
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital