Clinical trials: Hypovitaminosis A
Vitamin A Deficiency
Effect of Daily Consumption of Orange Maize on Breast Milk Retinol in Lactating Zambian Women
The purpose of the study is to determine whether daily consumption of beta-carotene biofortified maize will increase breast milk retinol concentration in lactating Zambian women.
- Trial name
- NCT01922713
- Testing
- white maize and a corn oil capsule, orange maize and a corn oil capsule, white maize and a vitamin A capsule
- Where
- Zambia
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Weight Gain, Anemia, Iron Deficiency
Egg Intervention During Pregnancy in Indonesia
The study consists of two arms: 1) intervention group using eggs as supplementary food given from 2nd trimester of pregnancy to birth, and 2) observational group of pregnant mothers.
- Conditions
- Weight Gain, Anemia, Iron Deficiency, Birth Weight, Birth Length
- Trial name
- PRECODE (NCT04694235)
- Testing
- Egg intervention
- Where
- Indonesia
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Down Syndrome, Vitamin D Deficiency
Effect of Exercise Intensity on Vitamin D
Children with Down's syndrome (DS) are more liable to vitamin D deficiency. Treating this deficiency with supplements is associated with the risk of intoxication due to increased intestinal absorption or decreased vitamin D…
- Trial name
- NCT05024110
- Testing
- High intensity treamill exercise training., Moderate intensity treamill exercise training.
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Taif University
Vitamin D Deficiency, Thoracic Surgery
Prevention of Vitamin D Deficiency Following Pediatric CHD Surgery: a Phase II Dose Evaluation Randomized Controlled Trial Comparing Usual Care With a High Dose Pre-operative Supplementation Regimen Based on the Institute of Medicine Daily Upper Tolerable Intake Level
Our research group has shown that almost all children with congenital heart disease (CHD) are vitamin D deficient following heart surgery.
- Conditions
- Vitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, Congenital
- Trial name
- HICCUPS 2 (NCT01838447)
- Testing
- Cholecalciferol
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Children's Hospital of Eastern Ontario
Vitamin B12 Deficiency
Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial
Vegetarians are known to be deficient in vitamin B12, due to a lack or absence of dietary animal produce, which can elevate homocysteine.
- Trial name
- NCT01661309
- Testing
- Inactive lozenge, Methylcobalamin
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of West London
Vitamin D Deficiency, Stem Cell Transplant Complications
A Randomized Phase IV Control Trial of Single High Dose Oral Vitamin D3 in Pediatric Patients Undergoing HSCT
Research has suggested that children with sufficient vitamin D levels undergoing hematopoietic stem cell transplant (HSCT) have improved outcomes, including lower incidences of infection and graft-versus-host disease (GVHD), as…
- Conditions
- Vitamin D Deficiency, Stem Cell Transplant Complications, Pediatric Cancer, Blood Disorder
- Trial name
- NCT03176849
- Testing
- Vitamin D3, Standard Vitamin D3 Supplementation
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Phoenix Children's Hospital
Hypophosphatasia (HPP)
A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)
This study aims to characterize the natural history of patients with severe perinatal or infantile onset HPP.
- Trial name
- NCT01419028
- Where
- 12 sites in United States, Australia and 5 more
- Volunteers
- 48 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Vitamin D Deficiency, Hypovitaminosis A
A Randomized Controlled Trial Testing The Effect Of A Multi-Nutrient Fortified Juice
The goal of this investigator-initiated study is to determine whether the fortification of orange juice with vitamin D, vitamin A, and vitamin E will enhance the vitamin D, vitamin A, and vitamin E status children ages 6-10 that…
- Conditions
- Vitamin D Deficiency, Hypovitaminosis A, Vitamin E Deficiency
- Trial name
- NCT01909063
- Testing
- Vitamin D, Vitamin D, Vitamin E, and Vitamin A, Control, 700 mg Calcium
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston University
Vitamin D Deficiency
Oral Vitamin D Substitution Weekly or Monthly and Adherence
Vitamin D deficiency (defined as 25(OH)-vitamin D serum level <50 nmol/l) is cured with supplementation by mouth. National guidelines recommend the administration of 800 IU cholecalciferol daily for an effective treatment…
- Trial name
- NCT03141593
- Testing
- Vitamin D: liquid form, start weekly, Vitamin D: liquid form, start monthly, Vitamin D: solid form, start weekly
- Where
- Switzerland
- Volunteers
- 97 people
- Sponsor
- University Hospital, Basel, Switzerland
Vitamin D Deficiency, Osteopenia of Prematurity
The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.
The aim of this study will be to assess the effectiveness of monitored vit D supplementation in a population of preterm infants and to identify whether the proper vit D supplementation in preterm infants can reduce the incidence…
- Conditions
- Vitamin D Deficiency, Osteopenia of Prematurity, Nephrolithiasis, Metabolic Bone Disease
- Trial name
- HIDVID (NCT06199102)
- Testing
- cholecalciferol/ Devikap
- Where
- Poland
- Volunteers
- 130 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Chronic Renal Failure
Serum Uremic Toxins and Histological Findings of the Blood Vessels in Dialysis Patients
Patients treated by chronic renal replacement therapy are exposed to cardiovascular problems and suffer from an accelerated and sever atherosclerosis.
- Trial name
- NCT00412139
- Where
- North Macedonia
- Volunteers
- 100 people
- Sponsor
- University of Skopje
Deficiency, Vitamin D, Insulin Resistance
Vitamin D Supplementation and and Glycemic Indexes
Age affect insulin sensitivity and the metabolism, and vitamin D status was shown to have a correlation with markers of insulin resistance.
- Trial name
- NCT03478475
- Testing
- cholecalciferol (Euro-Pharm International, Canada)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Université d'Auvergne
Type2diabetes
Type 2 Diabetes and Blood Brain Barrier Improvement
The majority of T2DM adults show thiamine (vitamin B1) deficiency which may contribute to impaired function. This study will examine patients with T2DM through brain MRI scans, cognition assessments, blood tests, and…
- Trial name
- NCT06322212
- Testing
- Thiamine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Psoriasis Vulgaris, Vitamin D Deficiency
Efficacy of Vitamin D3 for the Treatment of Psoriatic Patients With Vitamin D Deficiency and Insufficiency
The purpose of this research is to study whether vitamin D supplement can improve clinical outcome (PASI score) in psoriasis vulgaris with vitamin D insufficiency and deficiency.
- Trial name
- NCT01339741
- Testing
- Vitamin D3
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Vitamin D Deficiency, Periodontitis
25-Hydroxyvitamin D Levels in Patients With Periodontitis (Stage III)
Periodontitis; is an inflammatory disease of tissues characterized by bone destruction around the teeth. Vitamin D plays an important role in several inflammatory diseases by promoting the expression of inflammatory cytokines…
- Trial name
- NCT05343273
- Testing
- taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Vitamin D Deficiency
Comparison of 25-hydroxy Vitamin D Level in Caucasian Women Receiving Vitamin D Supplementation and Not Receiving Supplementation: a Randomized Controlled Trial.
The objective of this study is to assess whether vitamin D supplements are sufficient to increase females who are deficient or borderline deficient in vitamin D levels to normal levels.
- Trial name
- NCT00882505
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pediatric Migraine, Migraine Disorders, Brain
Comorbidity-Based Propranolol Use in Pediatric Migraine
This observational retrospective cohort study aims to identify clinical and biochemical predictors of response to propranolol prophylaxis in pediatric migraine.
- Conditions
- Pediatric Migraine, Migraine Disorders, Brain, Vitamin D Deficiency
- Trial name
- NCT07103031
- Testing
- Behavioral therapy, Propranolol
- Where
- Turkey (Türkiye)
- Volunteers
- 488 people
- Sponsor
- Kayseri University
COVID, Vitamin D Deficiency
Vitamin D Levels in SARS-CoV-2: Do Current Adequacy Thresholds Reflect Clinical Risk? Insights From a Large Turkish Cohort
Blood vitamin D levels may be associated with severity of viral infections. To find out If there is a statistically significant relation between blood 25-hydroxy vitamin D (25(OH)D) levels and disease severity, patients with…
- Trial name
- NCT04394390
- Testing
- vitamin d
- Where
- Turkey (Türkiye)
- Volunteers
- 1,100 people
- Sponsor
- Bursa City Hospital
Vitamin D Deficiency (10 ng/mL to 30 ng/mL)
Vitamin D as a Supplement Against Falls in Elderly Study
The role of vitamin D deficiency on increased risk for falls and physical dysfunction is unclear. It is also unclear if taking vitamin D improves physical function and reduces fall risk in older adults.
- Trial name
- D-SAFE (NCT01827345)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida
Polycystic Ovary Syndrome, Vitamin D Deficiency
The Effects of Vitamin D on Angiogenic Factors in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) affects 5 to 10% of women of reproductive age. It is characterized by a cluster of hyperandrogenism, hyperinsulinemia, menstrual dysfunction, hirsutism and infertility.
- Trial name
- NCT02460380
- Testing
- Vitamin D3
- Volunteers
- 93 people
- Sponsor
- Maimonides Medical Center