Clinical trials: Hypoxemia During Surgery
Hypoxemia During Surgery
Effect of Preoxygenation Position and Examination Position on Hypoxemia During Painless Gastrointestinal Endoscopy
To investigate the independent effects and interaction of pre-oxygenation position (left lateral vs left lateral with 30° head-up tilt) and examination position (left lateral vs left lateral with 30° head-up tilt) on hypoxemia…
- Trial name
- NCT07673042
- Testing
- Pre-oxygenation Position （left lateral position）, Examination Position（left lateral position ）, Pre-oxygenation Position（ left lateral head elevation in a 30-degree position）
- Where
- China
- Volunteers
- 208 people
- Sponsor
- General Hospital of Ningxia Medical University
Hypoxemia
The Open Lung Approach During One Lung Ventilation in Thoracic Surgery
Question: Ventilatory strategy to counterbalance the effect of one lung ventilation during thoracic surgery. Findings: the open lung approach improved oxygenation and lung compliance, reducing respiratory system driving pressure…
- Trial name
- NCT03435523
- Testing
- Recruitment maneuver
- Volunteers
- 24 people
- Sponsor
- University of Foggia
Lung Cancer (Diagnosis), Hypoxemia
The Effect of Semi-recumbent Position on Hypoxemia After Lung Segment/Lobe Surgery
Thoracoscopic surgery is the most common surgical approach in thoracic surgery, which reduces surgical trauma and postoperative pain compared with open thoracotomy, but postoperative complications should not be overlooked, with…
- Trial name
- NCT07060625
- Testing
- Semi-reclining position
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Hypoxemia During Surgery
Usefulness of High-flow Oxygen Therapy of Patients at Risk of Hypoxemia Undergoing Digestive Endoscopy Under Deep Sedation
The study investigates the use of high-flow oxygen therapy devices in patients at higher risk of complications during sedated digestive endoscopies.
- Trial name
- ENDOALF-TR (NCT07439822)
- Testing
- High-flow medical oxygen insufflation, Low-flow medical oxygen insufflation
- Where
- Spain
- Volunteers
- 326 people
- Sponsor
- Outcomes'10
Hypoxemia During Surgery, Hypoxia
Evaluation of the Effect of Sevoflurane and Propofol Hypotensive Anesthesia on Blood Antioxidant Levels and HIF 1 Levels
The aim of this study to evaluate the patients who underwent controlled hypotensive anesthesia under standardized depth of anesthesia with total intravenous anesthesia or inhalation anesthesia; preoperative and 30. ,60. ,120.
- Trial name
- NCT04246567
- Testing
- Mean Blood Pressure (MBP), Add to 0.5 mcg / kg fentanyl.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Hypoxemia During Surgery
Oxygen Reserve Index in Airway Surgery in Children
This study aimed to identify the effect of oxygen reserve index monitoring on the occurrence of oxygen desaturation (<90%) in pediatric patients undergoing airway surgery.
- Trial name
- NCT05214950
- Testing
- ORI monitoring
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Seoul National University Hospital
Hypoxemia During Surgery, Hypoxia, Brain
Effect of Hypotensive Anesthesia on Cerebral Perfusion and Blood Antioxidant Levels and HIF 1a
The aim of this study to evaluate the patients who underwent controlled hypotensive anesthesia under standardized depth of anesthesia; preoperative and postoperative blood HIF 1a, TAS, TOS measurement and cerebral perfusion…
- Trial name
- NCT04174417
- Testing
- systolic blood pressure (SBP), mean blood pressure (MBP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bezmialem Vakif University
Atelectasis
Role of Lung Ultrasound Imaging for Intraoperative Monitoring of Atelectasis During Laparoscopic Surgery
General anesthesia results in the development of atelectasis in the dependent areas of the lungs exposing patients to an increased risk of hypoxemia.
- Trial name
- NCT01749436
- Testing
- Lung ultrasound imaging examinations
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
One-Lung Ventilation, Hypoxemia During Surgery
Oxygen Reserve Index in One-Lung Ventilation During Elective Thoracic Operations
The investigators' goal is to perform an observational cohort study investigating the use of oxygen reserve index (ORi) in patients undergoing elective thoracic surgery and one-lung ventilation (OLV).
- Conditions
- One-Lung Ventilation, Hypoxemia During Surgery, Oxygen Reserve Index, Perfusion Index
- Trial name
- NCT05050552
- Testing
- Masimo Radical-7 Pulse CO-Oximeter
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Trakya University
Pulmonary Resection Surgery, One Lung Ventillation (OLV)
BMI-Adjusted PEEP During One-Lung Ventilation in Thoracic Surgery
One-lung ventilation (OLV) is required during many thoracic surgical procedures and is associated with reduced functional residual capacity, atelectasis, ventilation-perfusion mismatch, hypoxemia, and potentially…
- Conditions
- Pulmonary Resection Surgery, One Lung Ventillation (OLV), General Anesthetic
- Trial name
- SIMPLE-PEEP (NCT07851740)
- Testing
- Fixed PEEP, BMI-adjusted PEEP
- Where
- 4 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Jesús Manuel Nieves Alonso
Hypoxia
Effect of Different Positions During Extubation on Incidence of Hypoxemia in the Peri Extubation Period
Pediatric Obstructive Sleep Apnea Syndrome (OSAS) is common, often due to enlarged tonsils/adenoids. Tonsillectomy/adenoidectomy frequently performed under GA with tracheal intubation due to the age of children.
- Trial name
- NCT07231887
- Testing
- positioning during peri-extubation
- Volunteers
- 262 people
- Sponsor
- Assiut University
Pulmonary Complications, Hypoxemia During Surgery
Association of Different Tidal Volumes and Postoperative Pulmonary Complications
The incidence of lung cancer in China is increasing year by year. Currently, the treatment primarily based on video-assisted thoracoscopic surgery (VATS) is still considered the optimal approach for early-stage non-small cell…
- Conditions
- Pulmonary Complications, Hypoxemia During Surgery, Thoracic Surgery, Video Assisted, One Lung Ventillation (OLV)
- Trial name
- NCT07372378
- Volunteers
- 650 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hypoxemia During Surgery, Atelectasis
Usage of High Flow Nasal Cannula in Preventing Desaturations in Elderly Patients Going for Lower Limb Surgeries
To study the effect of high flow nasal cannula in comparisons with nasoprong used intraoperatively in patients oxygenation status
- Trial name
- NCT06054022
- Testing
- high flow nasal cannula, nasoprong oxyen 2Litres per minute
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Hypoxemia During Surgery
High-Flow Nasal Oxygen vs. Face Mask During Sedoanalgesia in Non-Intubated Thoracoscopic Pericardial Window Surgery
This is a prospective, randomized, parallel-group clinical trial designed to evaluate the effects of high-flow nasal oxygen therapy (HFNOT) versus conventional oxygen mask (COM) on perioperative hypoxia in patients undergoing…
- Trial name
- HIFI-NIVATS (NCT07432607)
- Testing
- High-Flow Nasal Oxygen Therapy (HFNOT), Conventional Oxygen Mask (COM)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ebru Girgin Dinc
Elderly Patients, Laparoscopic Surgery
Transnasal Microstream EtCO2 Reduces Hypoxemia During Emergence in Aged Post-Abdomen Surgery
This prospective, randomized controlled study aims to investigate whether transnasal microstream end-tidal carbon dioxide (EtCO₂) monitoring in the post-anesthesia care unit (PACU) reduces the incidence of postoperative hypoxemia…
- Conditions
- Elderly Patients, Laparoscopic Surgery, Postoperative Hypoxemia, Capnography
- Trial name
- NCT07652385
- Testing
- EtCO₂ Monitoring, Routine Monitoring
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Atelectasis, Postoperative Pulmonary, Bariatric Surgery
Postoperative Hypoxemia in Obese Patients
Postoperative atelectasis can cause postoperative hypoxia which might be avoided by applying pressure support during extubation of obese patients undergoing bariatric surgeries.
- Trial name
- RCT (NCT06589011)
- Testing
- Pressure Support Ventilation, spontaneously assisted breathing
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Theodor Bilharz Research Institute
Cerebral Hypoxia, Postoperative Delirium
Sevoflurane Decreases the Risk of Postoperative Delirium After Cerebral Hypoxemia During Surgery
The aim of this study is to distinguish possible differences in frequency of delirium after Volatile Induction and Maintenance of Anesthesia and Total Intravenous Anesthesia in case of undeliberate cerebral desaturation during…
- Trial name
- NCT02133638
- Testing
- Sevoflurane, Propofol
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- Negovsky Reanimatology Research Institute
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Hypoxemia
HFLVV for Hypoxemia in Robot-assisted Cardiac Surgery
These robot-assisted cardiac surgeries usually require single-lung ventilation (SLV) to facilitate surgical exposure. SLV creates ventilation/perfusion mismatch and shunt (Qs:Qt) through the collapsed lung and leads to hypoxemia.
- Trial name
- NCT04926649
- Testing
- Differential ventilation to the non-dependent lung
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Hypoxemia During Surgery
Prediction Model of Hypoxemia in Gastrointestinal Endoscopy Sedation
The incidence of hypoxemia during gastrointestinal endoscopy sedation is high, but there is still a lack of perfect prediction model of hypoxemia, which often leads to unpredictable respiratory complications.
- Trial name
- NCT06016998
- Where
- China
- Volunteers
- 1,023 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital