Clinical trials: ICD Shock
Inappropriate ICD Therapy, Appropriate ICD Therapy
Prevention of Inappropriate ICD Shocks
The aim of the present study is to investigate whether increasing detection zones can effectively reduce inappropriate ICD therapies in primary prevention patients.
- Trial name
- RISSY-ICD (NCT02044315)
- Testing
- ICD programming
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people
- Sponsor
- Yuksek Ihtisas Hospital
Heart Failure, Systolic, Left Ventricular Assist Device
STandardized Ultra-conservative Or Physician-directed ICD Programming for Continuous Flow LVAD Support
This study will evaluate the utilization of an ultra-conservative programming strategy to reduce shocks for ventricular arrhythmias (VA) among patients with heart failure, an implantable cardioverter-defibrillator (ICD) and…
- Conditions
- Heart Failure, Systolic, Left Ventricular Assist Device, ICD
- Trial name
- NCT04264182
- Testing
- ICD programming
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Cleveland Clinic
ICD, Sudden Cardiac Death
Ability of Home Monitoring® to Detect and Manage the Inappropriate Diagnoses in Implantable Cardioverter Defibrillators.
The purpose of the THORN registry is to show the ability of Home-Monitoring® to early identify and manage the inappropriate diagnoses of ventricular arrhythmia in ICD patients (i.e.
- Conditions
- ICD, Sudden Cardiac Death, Ventricular Fibrillation, Atrial Fibrillation
- Trial name
- THORN (NCT01594112)
- Where
- 55 sites in France
- Volunteers
- 512 people
- Sponsor
- Biotronik SE & Co. KG
Implantable Defibrillator Lead Dysfunction, Implantable Automatic Defibrillator Malfunction
Shock Testing to Unmask RV Lead and GEnerator Malfunction in ICD Patients: the SURGE-ICD Registry
Shock testing during ICD generator replacement has been omitted by many centers. A previous study revealed lead failures in internally cardioverted patients with previously normal HV-lead values.
- Conditions
- Implantable Defibrillator Lead Dysfunction, Implantable Automatic Defibrillator Malfunction, Implantable Defibrillator User
- Trial name
- Surge-ICD (NCT04858672)
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Universitätsklinikum Köln
Heart Failure, Death, Sudden, Cardiac
Sympathetic Nerve Activity and an Implantable Cardioverter Defibrillator in Heart Failure Patients
The aim of this study is to analyze whether the sympathetic tone, measured indirectly and directly by muscle sympathetic nerve activity recording, is elevated in patients with heart failure receiving an appropriate shock from…
- Trial name
- NCT00439790
- Testing
- Microneurography
- Where
- France
- Volunteers
- 109 people
- Sponsor
- University Hospital, Toulouse
Ventricular Tachycardia, Ventricular Fibrillation
The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock
The RAPTURE Study will determine whether dual chamber defibrillators with atrial prevention and termination therapies, minimized ventricular pacing, and remote monitoring will reduce the rate of inappropriate shocks and improve…
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation, Supraventricular Tachycardia
- Trial name
- RAPTURE (NCT00787800)
- Testing
- Dual Chamber ICD, Single Chamber ICD
- Where
- 4 sites in United States, Israel
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Implantable Defibrillator User, Stress Reaction
Self-Management Interventions After an ICD Shock
This study, "Biobehavioral Intervention to Reduce PTSD Symptoms After an ICD Shock," addresses a critical need in cardiology care by describing the feasibility and acceptability of a timely, highly promising…
- Conditions
- Implantable Defibrillator User, Stress Reaction, Ptsd, Stress Management
- Trial name
- NCT06037785
- Testing
- Self-Paced Self-Management (SPSM)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Sudden Cardiac Death, Implantable Defibrillator User
S-ICD French Cohort Study (HONEST)
Implantable cardioverter-defibrillators have been proven to be effective in the prevention of sudden cardiac death in high-risk patients.
- Trial name
- HONEST (NCT05302115)
- Testing
- S-ICD
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Paris Sudden Death Expertise Center
ICD, ICD SHOCKS
Dronaderone to Prevent Recurrent Implantable Cardioverter Defibrillator (ICD) Shocks
Recurrent ICD shocks are a serious problem in pts with ICD. Treatment failure with other antiarrhythmics and ablation are common. Dronedarone is a new antiarrhythmic drug with ion channel properties similar to amiodarone.
- Conditions
- ICD, ICD SHOCKS, DRONEDARONE
- Trial name
- NCT01430806
- Testing
- Dronedarone arm, Dronedarone
- Volunteers
- 20 people
- Sponsor
- Rabin Medical Center
Tachycardia
Optimal Anti-tachycardia Therapy in Implantable Cardioverter-defibrillator (ICD) Patients Without Pacing Indications
This study evaluates the impact of a new pacing mode avoiding unnecessary ventricular stimulation in combination with advanced dual chamber detection with slow VT management on the clinical outcome for hospitalization and…
- Trial name
- OPTION (NCT00729703)
- Testing
- Ovatio DR 6550
- Where
- 55 sites in United States, Belgium and 7 more
- Volunteers
- 462 people
- Sponsor
- LivaNova
Inappropriate Shocks From Implanted Defibrillator, ICD Replacement or Upgrade
Observational Study on Inappropriate Therapies
The purpose of the study is to assess the incidence of inappropriate shocks at 2 years, in a population of patients undergoing a generator replacement (VR/DR/CRT) or upgrade from a previously implanted ICD (VR/DR)
- Trial name
- OSIRIS (NCT04118803)
- Testing
- ICD replacement or upgrade
- Where
- 58 sites in United States, Austria and 9 more
- Volunteers
- 881 people
- Sponsor
- MicroPort CRM
Tachyarrhythmia
ASSURE Study - Arrhythmia Single Shock DFT Versus ULV: Risk Reduction Evaluation With ICD Implantations
The ASSURE Study will evaluate shock conversion performance when programming the first shock of an implantable cardioverter-defibrillation (ICD) is based on an implant test consisting of either 1) a single induction of…
- Trial name
- NCT00231426
- Testing
- ICD
- Where
- United States
- Sponsor
- Boston Scientific Corporation
Sudden Cardiac Arrest, Ventricular Tachycardia
A Feasibility Study on Prediction of an ICD Shock by ICD-derived Data
The primary hypothesis is that an ICD shock may be predicted days in advance by a combined score derived from different data obtainable from the ICD
- Conditions
- Sudden Cardiac Arrest, Ventricular Tachycardia, Ventricular Fibrillation
- Trial name
- PREDICT-ICDS (NCT01822145)
- Testing
- ICD
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Princess Margaret Hospital, Hong Kong
Sudden Cardiac Death
Assessment of Primary Prevention Patients Receiving An ICD - Systematic Evaluation of ATP
The primary objective is to understand the role of antitachycardia pacing (ATP) in primary prevention patients indicated for implantable cardioverter-defibrillator (ICD) therapy and programmed according to current guidance of…
- Trial name
- APPRAISE ATP (NCT02923726)
- Testing
- Arm 1 (ATP+Shock), Arm 2 (shock only)
- Where
- 134 sites in United States, Austria and 6 more
- Volunteers
- 2,692 people
- Sponsor
- Boston Scientific Corporation
Appropriate and Inappropriate Shock Therapy With ICD, Arrhythmias Detection
Arrhythmias Detection in a Real World Population
The study is a prospective multicenter registry. Consecutive patients with indications of implant / replacement or upgrade of implantable cardioverter defibrillator (ICD) will be enrolled.
- Trial name
- RHYTHM DETECT (NCT02275637)
- Testing
- implantable cardioverter defibrillator
- Where
- 12 sites in Italy
- Volunteers
- 10,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Arrhythmias, Cardiac
Stress Reduction to Reduce Risk for Arrhythmia in ICD Patients (The RISTA Study)
An implantable cardioverter defibrillator (ICD) is a small device that is implanted in the chest and uses electrical shocks to control arrhythmias, which are abnormal heart rhythms.
- Trial name
- RISTA (NCT00627263)
- Testing
- Stress reduction treatment (SRT) program
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Yale University
Defibrillators, Electrical Shock
LUKS-Leads Registry on Long-term Performance of ICD Leads
All patients having an implantable cardiac defibrillator (ICD) implanted and having follow-up at the Cantonal Hospital Lucerne (LUKS), the investigator center, are included in this retrospective ICD lead registry from 2006…
- Trial name
- NCT03521050
- Testing
- defibrillator lead
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- Luzerner Kantonsspital
Monomorphic Ventricular Tachycardia
Trial to Evaluate the Efficacy and Safety of Substrate Ablation of Monomorphic Ventricular Tachycardia
To compare the efficacy and safety of substrate-based radiofrequency catheter ablation vs. antiarrhythmic drug therapy in patients with ischemic cardiomyopathy and scar-related sustained monomorphic ventricular tachycardia.
- Trial name
- NCT03734562
- Testing
- Ablation, Antiarrhythmic drug
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Shock
Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication
Although shock therapy is effective in terminating ventricular tachycardia (VT), it can be painful to the patient and repetitive shocks can decrease a patient's quality of life.
- Trial name
- PROVIDE (NCT00743522)
- Testing
- ICD/ CRT-D
- Where
- United States
- Volunteers
- 1,670 people
- Sponsor
- Abbott Medical Devices
Pain Awareness From ICD Shocks
Assessment of Prepulse Inhibition for Shock Pain Reduction
Patient tolerance of pain from discharges of implantable cardioverter defibrillators (ICD's) is highly variable. It can be influenced by psychological factors, physical condition and the number of shocks delivered.
- Trial name
- NCT00193986
- Testing
- Arbitrary Waveform Defibrillator
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto