Clinical trials: ICH - Intracerebral Hemorrhage
Intracerebral Hemorrhage, Hemorrhagic Stroke, Intracerebral
Safety and Feasibility of Using Cerebrolysin in the Treatment of Primary Intracerebral Hemorrhage - a Prospective Randomized Open Blinded End-point Trial
This study is designed to determine the safety and feasibility of using Cerebrolysin in treating primary intracerebral hemorrhage (ICH).
- Conditions
- Intracerebral Hemorrhage, Hemorrhagic Stroke, Intracerebral, Hemorrhagic Stroke, Stroke
- Trial name
- CLINCH (NCT06899464)
- Testing
- 14-day Cerebrolysin treatment, Standard of Care (SOC)
- Volunteers
- 30 people
- Sponsor
- Cardinal Stefan Wyszynski University
Ischemic Stroke, Subarachnoid Hemorrhage, Aneurysmal
Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases
Change and effect of cerebral autoregulation during targeted temperature management in neurocritical patients
- Conditions
- Ischemic Stroke, Subarachnoid Hemorrhage, Aneurysmal, Sepsis, TBI (Traumatic Brain Injury)
- Trial name
- NCT04728438
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xiangya Hospital of Central South University
Basal Ganglia Hemorrhage, Intraventricular Hemorrhage
RAINBOW-ICH Trial of AI Guided Minimally Invasive Neurosurgery for ICH
Intracerebral hemorrhage (ICH) is one of the most devastating forms of stroke, with high rates of death and disability worldwide. Despite advances in medical and surgical care, effective therapeutic options remain limited.
- Conditions
- Basal Ganglia Hemorrhage, Intraventricular Hemorrhage, Brainstem Stroke, Intracranial Hemorrhage, Spontaneous
- Trial name
- RAINBOW-ICH (NCT07205263)
- Testing
- AI-assisted robotic-guided endoscopic hematoma evacuation, Conventional craniotomy, AI-assisted robotic-guided puncture and hematoma evacuation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Subarachnoid Hemorrhage, Intracerebral Hemorrhage
Safety and Efficacy of Nicardipine for the Control of Blood Pressure After SAH
The purpose of this research is to explore ways to improve and simplify control of blood pressure in patients with SAH or ICH. This research will be done by comparing tow different medications that are routinely used to help…
- Trial name
- NCT00490464
- Testing
- Nicardipine and Nipride
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Illinois Chicago
Cerebral Hemorrhage, Intracranial Hemorrhages
Study of Antithrombotic Treatment After IntraCerebral Haemorrhage
The study evaluates the effects of antithrombotic drugs (anticoagulant drugs or antiplatelet drugs) for prevention of ischaemic events in patients With recent intracerebral haemorrhage.
- Conditions
- Cerebral Hemorrhage, Intracranial Hemorrhages, Atrial Fibrillation, Anticoagulant-Induced Bleeding
- Trial name
- STATICH (NCT03186729)
- Testing
- Antithrombotic Agent
- Where
- 3 sites in Denmark, Norway and 1 more
- Volunteers
- 134 people
- Sponsor
- Oslo University Hospital
Intracerebral Hemorrhage
Trial of Cooling for Patients With Excel Cryo Cooling System in Intracerebral Hemorrhage (ICH)
The purpose of this study is to determine if cooling the neck of patients with ICH decreases brain temperature. In addition, the investigators will determine if the device improves the delivery of oxygen to the brain.
- Trial name
- CCSICH (NCT01933230)
- Testing
- Excel Cryo Cooling System
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
Coma, Stroke
Short-term Cervical Spinal Cord Stimulation in Patients With Disorders of Consciousness After Intracerebral Hemorrhage
Disorders of consciousness (DOC) refers to the persistent loss of consciousness after 28 days in patients with brain injury caused by trauma, stroke, or hypoxia. It includes coma, vegetative state, and minimally conscious state.
- Trial name
- SCS-ICH (NCT05922644)
- Testing
- SCS, Conventional
- Where
- China
- Volunteers
- 344 people
- Sponsor
- Beijing Tiantan Hospital
Hemorrhagic Stroke, Intracerebral Hemorrhage (ICH)
Efficacy, Safety and Tolerability of BAF312 Compared to Placebo in Patients With Intracerebral Hemorrhage (ICH).
This is a randomized, placebo-controlled, subject and investigator-blinded study to evaluate efficacy, safety and tolerability of BAF312 in participants with intracerebral hemorrhage (ICH)
- Trial name
- NCT03338998
- Testing
- BAF312 solution, BAF312 tablet
- Where
- 11 sites in United States
- Volunteers
- 32 people
- Sponsor
- Novartis Pharmaceuticals
Intracerebral Haemorrhage (ICH), Hypertension
Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial
An investigator initiated and conducted, multicentre, international, double-blinded, placebo-controlled, parallel-group, randomised controlled trial to determine the effect of more intensive blood pressure control provided by a…
- Trial name
- TRIDENT (NCT02699645)
- Testing
- telmisartan 20mg, amlodipine 2.5mg, and indapamide 1.25mg
- Where
- 58 sites in Australia, Brazil and 8 more
- Volunteers
- 1,671 people
- Sponsor
- The George Institute
Intracerebral Hemorrhage, Acute Ischemic Stroke
Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage
This study aims to determine whether in-bed cycle ergometry, early in the hospital course after a brain hemorrhage could balance damaging and reparative inflammation in the brain.
- Trial name
- BEACH (NCT04027049)
- Testing
- Supine cycle ergometry of the lower extremities
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University
Intracerebral Hemorrhage, Hypertension
Antihypertensive Treatment in Acute Cerebral Hemorrhage
The purpose of this trial is to evaluate the safety and effectiveness of lowering blood pressure using nicardipine in persons with acute hypertension associated with intracerebral hemorrhage.
- Conditions
- Intracerebral Hemorrhage, Hypertension, Stroke
- Trial name
- ATACH (NCT00415610)
- Testing
- nicardipine
- Where
- 12 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
Intracerebral Hemorrhage, Low T3 Syndrome
Efficacy of Thyroid Hormone Replacement for Secondary Hypothyroidism Following Intracerebral Hemorrhage
Low levels of serum triiodothyronine (T3) thyroid hormones (T4) are a strong predictor of mortality and poor prognosis in critical care patients. Few reports, however, have focused on neurocritical patients.
- Conditions
- Intracerebral Hemorrhage, Low T3 Syndrome, Neurocritical Care, Hormone Replacement Therapy
- Trial name
- NCT06353555
- Testing
- Euthyrox
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Aphasia, Acquired, Aphasia
Aphasia Physical EXercise Study: Randomized Trial
The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent
- Trial name
- APEX (NCT07281313)
- Testing
- High-intensity physical exercise, Low-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, Berkeley
Intracerebral Hemorrhage
Short-term And Longer-term Cognitive Impact Of Neurochecks
The proposed research plan seeks to understand the impact of sleep disruption in the Neurological Intensive Care Unit (ICU) on older patients with acute brain injury (ABI).
- Trial name
- NCT06219889
- Testing
- Frequency of neurochecks
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Intracerebral Hemorrhage, Stroke
The Second Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial
The purpose of this academic lead study is to determine if a treatment strategy of early intensive blood pressure (BP) lowering compared to conservative BP lowering policy in patients with elevated blood pressure within 6 hours…
- Conditions
- Intracerebral Hemorrhage, Stroke, Hypertension
- Trial name
- INTERACT2 (NCT00716079)
- Testing
- Blood pressure management policies
- Where
- 62 sites in United States, Argentina and 17 more
- Volunteers
- 2,839 people
- Sponsor
- The George Institute
Traumatic Brain Injury, Ischemic Stroke
Shared Decision Making to Improve Goals-of-Care Decisions for Families of Severe Acute Brain Injury Patients
Severe acute brain injury (SABI), including large artery acute ischemic stroke, intracerebral hemorrhage, and severe traumatic brain injury continue to be the leading cause of death and disability in adults in the U.S.
- Conditions
- Traumatic Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- NCT03833375
- Testing
- Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- University of Massachusetts, Worcester
Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage Lobar
Colchicine for the Prevention of Recurrence in Cerebral Amyloid Angiopathy RElated IntraCerebral Hemorrhage
The goal of this clinical trial is to assess the safety and tolerability of colchicine for preventing intracerebral haemorrhage (ICH) recurrence in patients with cerebral amyloid angiopathy (CAA)-ICH at high risk of recurrence.
- Trial name
- CARE-ICH (NCT07026994)
- Testing
- Colchicine 0.5mg
- Where
- 3 sites in China
- Volunteers
- 80 people
- Sponsor
- Huashan Hospital
Stable Angina, Unstable Angina
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial…
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction, Unheralded Coronary Heart Disease Death
- Trial name
- NCT03425305
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Intracerebral Hemorrhage
Optimization of the Management of Non-Traumatic Intracerebral Hemorrhage (OPT-ICH)
Intracerebral non-traumatic intraparenchymal hemorrhages (ICH) account for 15 to 20% of strokes. One third of the patients dies within the month following ICH, and survivors often experience residual disability with a high risk…
- Trial name
- OPT-ICH (NCT06802588)
- Where
- 3 sites in France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Tours
Cerebral Hemorrhage
Diagnostic Utility of MRI in Intracerebral Hemorrhage
The overall aim of this project is to prospectively determine whether MRI can improve the conventional neuroradiological evaluation (CT with or without cerebral angiography) of patients with a spontaneous ICH or IVH.
- Trial name
- DASH (NCT00363662)
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University