Clinical trials: ICU Acquired Weakness
ICU-acquired Weakness
Evidence-based, Customized, Motion-recognition Rehabilitation System Development for Bed-ridden Patients - Validation of Effectiveness: Rehabit: Swim
This pilot study aims to evaluate the efficacy, safety, feasibility, and user satisfaction of "Rehabit: swim," a customized, evidence-based, motion-recognition-based rehabilitation exergame designed for hospitalized patients with…
- Trial name
- NCT07896057
- Testing
- Rehabilitation
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Asan Medical Center
Implementation Science, Delirium
Behavioral Economic & Staffing Strategies in the ICU
The overarching goal of this study is to support the "real world" assessment of strategies used to foster adoption of several highly efficacious evidence-based practices in healthcare systems that provide care to critically ill…
- Conditions
- Implementation Science, Delirium, Critical Illness, Mechanical Ventilation Complication
- Trial name
- BEST-ICU (NCT06184945)
- Testing
- Realtime audit and feedback, RN Implementation Facilitator
- Where
- 3 sites in United States
- Volunteers
- 16,500 people
- Sponsor
- University of Nebraska
Critical Illness, ICU-acquired Weakness
Beyond Voluntary Effort: Reliability and Validity of Magnetic Femoral Nerve Stimulation for Assessing Quadriceps Strength in Critically Ill Patient
Intensive care unit-acquired weakness (ICU-AW) is a common complication of critical illness and can negatively affect recovery and long-term physical functioning.
- Trial name
- TWITCH FORCE (NCT07891273)
- Testing
- Magnetic Femoral Nerve Stimulation
- Volunteers
- 33 people
- Sponsor
- Daniel Langer
Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication
Prone Positioning and Thoracoabdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing
Ventilator-induced diaphragmatic dysfunction and intensive care unit (ICU)-acquired weakness are two consequences of prolonged mechanical ventilation and critical illness in patients with acute respiratory distress syndrome…
- Conditions
- Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication, ICU Acquired Weakness
- Trial name
- NCT05826847
- Testing
- Prone Positioning, Thoracoabdominal Binding, Control
- Where
- Chile
- Volunteers
- 14 people
- Sponsor
- University of Chile
Hospitalized Patients, ICU Hospitalization
Virtual Reality in Intensive Care Unit: Patient Satisfaction, Clinical and Functional Outcomes, Feasibility
Background: Virtual reality is recognized as a progressive technology with the potential to enhance the rehabilitation process. Immersive virtual reality-based treatments can improve motor outcomes in physical rehabilitation…
- Conditions
- Hospitalized Patients, ICU Hospitalization, Intensive Care Unit-acquired Weakness
- Trial name
- NCT07089134
- Testing
- reabilitação fisioterapêutica tradicional, fisioterapia utilizando realidade virtual imersiva
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Hospital Sirio-Libanes
ICU Acquired Weakness, Intensive Care Neuropathy
Predictive Validity of the Chelsea Critical Care Physical Assessment Tool (CPAx) for Regaining Autonomy Three Months After ICU Discharge
This single-center observational study aims to explore the relationship between the CPAx score (Chelsea Critical Care Physical Assessment Tool), measured at ICU discharge, and the 6-minute walk test (6MWT) distance performed 3…
- Trial name
- CPAx-Predict (NCT07167121)
- Testing
- CPAx
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Intercommunal Elbeuf-Louviers-Val de Reuil
ICU Acquired Weakness
ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients.
This study is testing whether a non-invasive nerve monitoring device (TetraGraph) can accurately detect early signs of ICU-acquired weakness by comparing readings from the device with standard nerve conduction/EMG tests done by a…
- Trial name
- ICU CONNECT (NCT07699562)
- Testing
- TetraGraph, Electromyography, Nerve conduction studies
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Sepsis, Critical Illness
MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients
The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in the ICU (Intensive Care Unit) who are at risk of losing muscle strength.
- Conditions
- Sepsis, Critical Illness, ICU-acquired Muscle Weakness, ICU-acquired Weakness
- Trial name
- ICUAW (NCT07362862)
- Testing
- Electrical Muscle Stimulation System
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Health Discovery Labs
ICU-acquired Weakness, Mechanical Ventilation
eCASH and Early Goal-Directed Mobilization to Prevent ICU-Acquired Weakness
This single-center, prospective, randomized controlled trial aims to evaluate whether an eCASH concept-based analgesia and sedation strategy combined with early goal-directed mobilization can reduce the incidence of intensive…
- Conditions
- ICU-acquired Weakness, Mechanical Ventilation, Critical Illness
- Trial name
- eCASH-EGDM (NCT07677488)
- Testing
- eCASH-Based Analgesia and Sedation Strategy Combined With Early Goal-Directed Mobilization, Routine ICU Nursing Care
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The First Affiliated Hospital of Soochow University
ICU Acquired Weakness, Post Intensive Care Unit Syndrome
Muscle Recovery After Critical Illness
The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to recover muscle after critical illness, while exploring which…
- Conditions
- ICU Acquired Weakness, Post Intensive Care Unit Syndrome, Muscle Weakness, Critical Illness
- Trial name
- TRACER (NCT05537298)
- Where
- 3 sites in United States
- Volunteers
- 209 people
- Sponsor
- Esther Dupont-Versteegden
ICU-acquired Weakness, Critical Illness Polyneuropathy
Shear Wave Elastography of Peripheral Nerves for Early Diagnosis of ICU-acquired Weakness
This study aims to determine whether shear wave elastography (SWE), a non-invasive ultrasound technique that measures nerve stiffness, can help detect ICU-acquired weakness (ICU-AW) early in critically ill patients.
- Conditions
- ICU-acquired Weakness, Critical Illness Polyneuropathy, Critical Illness Myopathy
- Trial name
- NCT07594249
- Testing
- Nerve Ultrasound with Shear Wave Elastography
- Where
- China
- Volunteers
- 98 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
ICU Acquired Weakness, Sepsis
ICU Combined Assessment of Cardio-Respiratory Exercise
This study aims to investigate how sepsis and critical illness can impair the cardiovascular system and microcirculation in intensive care unit (ICU) patients, which can lead to long-lasting muscle weakness/dysfunction or…
- Conditions
- ICU Acquired Weakness, Sepsis, Shock, Critical Illness
- Trial name
- ICU-CARE (NCT06193980)
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
COVID-19, Critical Illness
REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19
Multicenter, prospective, randomized controlled trial providing mobile health supported physical rehabilitation to 120 patients who have been critically ill with COVID-19 and who complete at least one exercise session.
- Conditions
- COVID-19, Critical Illness, ICU Acquired Weakness, PICS
- Trial name
- REMM-HIIT-CoV (NCT05218083)
- Testing
- REmotely monitored, Mobile health supported Multidomain Rehabilitation Program with High Intensity Interval Training (REMM-HIIT)
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Duke University
Pulmonary Function, Colectomy
Effect of Arm Cycling Exercise on Pulmonary Functions After Colectomy In Elderly
This study will be done to investigate the effect of arm cycling on exercise and functional capacity, arterial blood gases, pulmonary functions, diaphragmatic excursion, time to peak inspiratory amplitude, physical function…
- Conditions
- Pulmonary Function, Colectomy, Colorectal Cancer, Post-operative Rehabilitation
- Trial name
- NCT06876961
- Testing
- Arm cycling exercise, The traditional physical therapy program
- Where
- Bahrain
- Volunteers
- 60 people
- Sponsor
- Cairo University
Critical Illness, Sarcopenia
Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors
Older ICU survivors with ICU acquired weakness (ICUAW) are malnourished, sarcopenic, and functionally debilitated as a consequence of the high burden of comorbidities common in the elderly.
- Conditions
- Critical Illness, Sarcopenia, ICU Acquired Weakness
- Trial name
- ProMoTE (NCT05326633)
- Testing
- MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Maryland, Baltimore
ICU Acquired Weakness (ICUAW)
Feasibility and Safety of Digital Rehab Platform for Bedridden Patients
Study Title Rehabilitation Program for Bedridden Patients Using Digital Devices Study Purpose This study aims to evaluate the effectiveness of a rehabilitation program using digital devices and apps for bedridden patients in a…
- Trial name
- NCT06849765
- Testing
- Rehabilitation
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Asan Medical Center
ICU Acquired Weakness (ICUAW)
Feasibility of a Digital Rehabilitation Platform in Patients After ICU Discharge
This study aims to evaluate the feasibility, usability, and clinical effectiveness of a digital rehabilitation platform in adult patients discharged from the intensive care unit (ICU).
- Trial name
- NCT07489092
- Testing
- Digital Rehabilitation Group
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Asan Medical Center
ICU Acquired Weakness
Development of an Early Warning Model for Intensive Care Unit-Acquired Weakness in Mechanically Ventilated Children
Acquired weakness (AW) is a common complication among patients in the Intensive Care Unit (ICU). It is a systemic muscle weakness and dysfunction associated with critical illness, often related to prolonged bed rest, mechanical…
- Trial name
- NCT07150637
- Testing
- ICU-AW
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Children's Hospital of Fudan University
ICU Acquired Weakness
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level
Acquired weakness (AW) is a common complication among patients in the Intensive Care Unit (ICU). It is a systemic muscle weakness and dysfunction associated with critical illness, often related to prolonged bed rest, mechanical…
- Trial name
- NCT07150650
- Testing
- ICU-AW
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Children's Hospital of Fudan University
ICU Acquired Weakness, Muscle Atrophy
Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )
Intensive Care Unit Acquired Weakness (ICUAW) describes muscle weakness that occurs in around 40% of patients during an intensive care stay.
- Conditions
- ICU Acquired Weakness, Muscle Atrophy, Energy Malnutrition Protein, Quality of Life
- Trial name
- NCT05919940
- Testing
- Dietary Supplement: additional substitution of protein, Neuromuscular electrical stimulation, Early Mobilization
- Where
- 4 sites in Austria, Germany
- Volunteers
- 40 people
- Sponsor
- Technical University of Munich