Clinical trials: ICU Mortality
Sepsis, Acute Renal Failure
Inferior Vena Cava Collapsibility and Distensibility Assessment in Critical Care.
This study will help in determining the impact of assessment of Inferior Vena Cava Collapsibility and Distensibility Index (IVC CI and DI) through Point Of Care Ultra Sound (POCUS), for the fluid management of critically ill…
- Conditions
- Sepsis, Acute Renal Failure, Acute Gastroenteritis, Diabetic Ketoacidosis
- Trial name
- NCT06516692
- Testing
- Inferior Vena Cava Collapsibility/distensibility Index (IVC CI/DI) assessment
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Pneumonia
5 Years Mortality-rate in Patients Treated for Severe Pneumonia in an ICU - a Retrospective Study
Severe pneumonia has a high in-hospital mortality. There are few studies which investigate the long-term mortality in patients that are discharged alive from the hospital.
- Trial name
- pneumonia (NCT02212093)
- Where
- Norway
- Volunteers
- 236 people
- Sponsor
- University Hospital, Akershus
Elderly Patients Visiting the Emergency Department
Impact on Mid-term Mortality of Guidelines for ICU Admission of Elderly Patients Arriving in Emergency Departments
Admitting a very elderly patient to the Intensive Care Unit (ICU) is one of the most difficult clinical challenges in medicine. There are few data to help guide clinicians in this area: estimates of the benefits of ICU admission…
- Trial name
- ICECUBII (NCT01508819)
- Testing
- recommendations to admit to ICU all the patients included
- Where
- France
- Volunteers
- 3,036 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiac Surgery
Intravenous Amino Acid Therapy for Kidney Protection in Cardiac Surgery.
To date, no pharmacological agents are proven efficacious in treating perioperative AKI. There is a strong biological rationale for the administration of amino acid in the management of patients at risk of AKI with increases in…
- Trial name
- PROTection (NCT03709264)
- Testing
- Amino Acids
- Where
- 22 sites in Croatia, Italy and 1 more
- Volunteers
- 3,511 people
- Sponsor
- Università Vita-Salute San Raffaele
Vasculitis, Systemic Lupus Erythematosus
Predictors of Mortality in Patients With Autoimmune Diseases Admitted to the Intensive Care Unit
Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, myositis, or anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, may affect multiple organ systems.
- Conditions
- Vasculitis, Systemic Lupus Erythematosus, Myositis
- Trial name
- NCT04022655
- Testing
- ICU Care
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Göttingen
Influenza, Critical Illness
Lung Bacteriobiota and Influenza Mortality
Influenza is a potentially lethal disease still responsible for thousands excess deaths both in Europe and the United States. Despite the use of neuraminidase inhibitors, its treatment is mostly based on symptomatic care.
- Trial name
- MicroFlu (NCT04131296)
- Testing
- influenza screening
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- University of Bordeaux
Acute Respiratory Failure, Critical Illness
Lactate/Albumin Ratio and Mortality in Respiratory Failure
This retrospective observational study aims to evaluate the association between the lactate-to-albumin ratio (LAR) measured at ICU admission and 28-day mortality in adult patients admitted to the intensive care unit with acute…
- Conditions
- Acute Respiratory Failure, Critical Illness, Mortality, Mortality Prediction
- Trial name
- NCT07909226
- Testing
- Assessment of Admission Serum Lactate-to-Albumin Ratio (LAR)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,250 people
- Sponsor
- Kocaeli City Hospital
Septic Shock, Sepsis
Examination of ADMA Serum Level and DDAH II
Examination of ADMA (Asymmetric-Dimethylarginine)-serum level and DDAH II (Dimethylarginine Dimethylaminohydrolase)- Polymorphism in patients with severe Sepsis and septic shock as prognostic value.
- Trial name
- ADSeS (NCT01632059)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cancer, Frailty
Association of ICU Admission Time, Age Stratification, and Clinical Frailty Scale With 30-Day Mortality in Geriatric Oncology Patients
Geriatric oncology patients frequently require intensive care admission and are at increased risk of adverse outcomes due to advanced age, frailty, and critical illness.
- Conditions
- Cancer, Frailty, Mortality
- Trial name
- NCT07825090
- Testing
- Observation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Septic Shock, Acute Renal Failure (as Defined by the "Failure" Stage of the RIFLE Classification)
I.D.E.A.L.-I.C.U. (Initiation of Dialysis EArly Versus deLayed in Intensive Care Unit)
The purpose of this multicentric, randomized controlled trial is to assess whether the timing of renal replacement therapy initiation (early vs delayed) has an impact on mortality at 90 days in patients with severe acute kidney…
- Trial name
- IDEAL-ICU (NCT01682590)
- Testing
- Renal Remplacement Therapy
- Where
- 27 sites in France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Respiratory Failure, Circulatory Failure
ICU Background Early Awareness for Critical deterioratiON
The study will compare ICU sub-units, those with additional support of a clinician awareness system, ICU Beacon, and those receiving the standard of care.
- Conditions
- Respiratory Failure, Circulatory Failure, Mortality, Organ Dysfunction
- Trial name
- BEACON (NCT07119411)
- Testing
- ICU Beacon
- Where
- Switzerland
- Volunteers
- 1,962 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Acute Kidney Failure, Critical Illness
Effect of Protein Dosage on Persistent Acute Renal Failure in Critically Ill Patients.
Background: Acute kidney injury (AKI) is common in critically ill patients and is associated with worse outcomes, including longer ICU stay, need for dialysis, and higher mortality.
- Conditions
- Acute Kidney Failure, Critical Illness, Protein Intake, Nutritional Support
- Trial name
- NCT07631221
- Where
- 6 sites in Argentina
- Volunteers
- 344 people
- Sponsor
- Hospital Italiano de Buenos Aires
COVID-19, Critical Illness
Analysis of Mortality of Critically Ill Patients With COVID-19
The recent pandemic of the COVID-19 disease has caused a national health emergency due to its severity and the clinical and social consequences of the disease. Crude mortality in Spain is 9.2%.
- Conditions
- COVID-19, Critical Illness, Effectiveness, Outcome, Fatal
- Trial name
- NCT04379258
- Where
- Spain
- Volunteers
- 868 people
- Sponsor
- Hospital Universitario Getafe
Trauma, Multiple, Trauma Injury
Factors Affecting Mortality and Morbidity in Trauma Patients Followed in Intensive Care Unit
In this study, the demographic and clinical characteristics of trauma patients followed up in the Intensive Care Unit of the Anesthesiology and Reanimation Clinic of the Health Sciences University Okmeydanı Training and Research…
- Trial name
- trauma (NCT05175872)
- Where
- Turkey (Türkiye)
- Volunteers
- 194 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Parenteral Nutrition
Study Comparing a Soybean Oil-Based With an Olive Oil-Based Lipid Emulsion in ICU Patients Requiring TPN
Many hospitalized patients who are malnourished or not eating receive intravenous feeding or total parenteral nutrition (TPN). Despite improving nutrition, TPN may increase the risk of infections and hospital complications.
- Trial name
- TPN2 (NCT00672854)
- Testing
- ClinOleic 20% Intravenous Emulsion, Intralipid, 20% Intravenous Emulsion
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Intertrochanteric Femur Fracture, Hip Fracture Surgeries
Inflammatory Indices, Early Mortality, and ICU Stay in Geriatric PFN Patients
This retrospective observational cohort study aims to evaluate the association between preoperative and postoperative inflammatory indices and early postoperative outcomes in geriatric patients undergoing proximal femoral nailing…
- Conditions
- Intertrochanteric Femur Fracture, Hip Fracture Surgeries, Geriatric Anesthesia
- Trial name
- PFN-RAR (NCT07607886)
- Where
- Turkey (Türkiye)
- Volunteers
- 233 people
- Sponsor
- Saglik Bilimleri Universitesi
Invasive Pulmonary Aspergillosis, Morality
Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study.
Invasive tracheobronchial aspergillosis (ITBA) is an uncommon, but severe clinical form of Invasive Pulmonary Aspergillosis (IPA) in which the fungal infection is entirely or predominantly confined to the tracheobronchial tree.
- Trial name
- ITBA (NCT04077697)
- Testing
- RT-PCR for influenza
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Sepsis, Syndecan 1
Effect of Sepsis Adsorption Column on Syndecan-1 and Mortality
This observational, cross-sectional, single-center study aims to investigate the effect of extracorporeal sepsis adsorption column therapy on plasma Syndecan-1 levels and clinical outcomes in patients with sepsis.
- Conditions
- Sepsis, Syndecan 1, Extracorporeal Sepsis Adsorption Column
- Trial name
- NCT07033910
- Testing
- sepsis adsorption column
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Oral MENTEŞ
Sepsis
Prognostic Value of the CALLY Index in Patients With Sepsis
This retrospective observational study evaluates the prognostic value of the C-reactive protein-albumin-lymphocyte (CALLY) index in adult patients with sepsis admitted to the intensive care unit (ICU).
- Trial name
- CALLY-SEP (NCT07285499)
- Where
- Turkey (Türkiye)
- Volunteers
- 276 people
- Sponsor
- Ankara University
Mechanical Ventilation Complication, Mechanical Power
LPP , MP and DP:Relation With Mortality and SOFA in Mechanically Ventilated Patients in ER, Ward and ICU
Prospective, observational, longitudinal study, September 2019 to March 2020 of all adult patients who required invasive mechanical ventilation treated at General Hospital of Zone 11 IMSS in Piedras Negras, Coahuila.
- Conditions
- Mechanical Ventilation Complication, Mechanical Power, Driving Pressure, Lung Protective Ventilation
- Trial name
- LUMEDRI-MORT (NCT04193254)
- Where
- Mexico
- Volunteers
- 63 people
- Sponsor
- JOSE IVAN RODRIGUEZ DE MOLINA SERRANO