Clinical trials: ICU Survivorship
Mechanical Ventilation, Duration of Treatment
Ultrasound of Accessory Respiratory Muscles
The aim of this study is to compare the diameter of accessory respiratory muscles in patients with respiratory diseases and patients without such diseases, and to determine whether there is a connection between the…
- Conditions
- Mechanical Ventilation, Duration of Treatment, Survival
- Trial name
- NCT04519450
- Testing
- Mindray TE7 ultrasound machine
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Osijek University Hospital
Long-term Outcome, Survival
Predictive Value of Bio-impedance Vector Analysis on Long-term Outcome in ICU Patients
Phase angle, derived from bioimpedance analysis (BIA), reflects tissue quality and quantity in which cell mass, membrane integrity and hydration state are represented.
- Trial name
- NCT04449796
- Where
- Netherlands
- Volunteers
- 1,025 people
- Sponsor
- Frisius Medisch Centrum
Localized Infection, Sepsis
The Procalcitonin and Survival Study
This is a randomised, single blinded, multicentre trial to evaluate whether daily procalcitonin (PCT) measurements and immediate diagnostic and therapeutic responses to abnormal values and day-to-day changes can reduce the…
- Conditions
- Localized Infection, Sepsis, Multiple Organ Failure
- Trial name
- PASS (NCT00271752)
- Testing
- Earlier therapeutic changes regarding infection
- Where
- 9 sites in Denmark
- Volunteers
- 1,200 people
- Sponsor
- Danish Procalcitonin Study Group
Stress Disorders, Post-Traumatic
PTSD After ICU Survival - Caring for Patients With Traumatic Stress Sequelae Following Intensive Medical Care
During the PICTURE trial a short narrative therapy (narrative exposure therapy adapted for primary care) for patients with posttraumatic stress disorder (PTSD) after intensive care treatment is to be carried out by their general…
- Trial name
- PICTURE (NCT03315390)
- Testing
- "Narrative Exposure Therapy"-oriented intervention, improved treatment as usual (iTAU)
- Where
- 2 sites in Germany
- Volunteers
- 319 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Polytrauma
Comparing Exponential Injury Severity Score (EISS) With Injury Severity Score (ISS) and New Injury Severity Score (NISS)
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.
- Trial name
- NCT06653816
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Assiut University
Delirium
pRophylactic halopEriDol Use for Delirium in iCu patiEnts With a High Risk for Delirium
The aim of this study is to determine the effects of a low dosage of prophylactic haloperidol in patients with a high risk to develop delirium, defined by an expected ICU length of stay of >1 day.
- Trial name
- REDUCE (NCT01785290)
- Testing
- Haloperidol 1 mg/q8h, Haloperidol 2 mg/q8h
- Where
- Netherlands
- Volunteers
- 1,800 people
- Sponsor
- Radboud University Medical Center
Survival After IPA, Risk Factors for IPA
Diagnosis of Invasive Pulmonary Aspergillosis (IPA) in Critically Ill Patients
Invasive pulmonary aspergillosis (IPA) is difficult to diagnose and remains a cause of high morbidity and mortality in critically ill patients in the ICU.
- Trial name
- DipA (NCT01866020)
- Where
- Germany
- Volunteers
- 85 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Critical Illness, COVID-19 Pneumonia
Acute Kidney Injury in Coronavirus Disease-19 (COVID-19) Patients Admitted to the Intensive Care Unit (ICU)
The aim of this study is to evaluate the rate and outcomes of COVID-19 associated acute kidney injury (AKI) and use of kidney replacement therapy (KRT) in critically ill COVID-19 patients in ICUs in several large hospitals in…
- Conditions
- Critical Illness, COVID-19 Pneumonia, Acute Kidney Injury
- Trial name
- COVID-AKI-B (NCT04997915)
- Testing
- Observational study exploring the epidemiology and outcomes of AKI in critical COVID-19 patients admitted to the ICU
- Where
- 9 sites in Belgium
- Volunteers
- 1,286 people
- Sponsor
- University Hospital, Ghent
Covid19, Hypoxic Respiratory Failure
SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival
Patients suffering lung failure, possibly from COVID-19 or hypoxic lung failure, will need life-saving support from a breathing machine.
- Trial name
- SAVE-ICU (NCT04415060)
- Testing
- Isoflurane Inhalant Product, Sevoflurane inhalant product
- Where
- 13 sites in Canada
- Volunteers
- 800 people
- Sponsor
- Sunnybrook Health Sciences Centre
Covid19, Acute Respiratory Failure
Survival Rates and Longterm Outcomes After COVID-19
The study 'Survival rates and long-term outcomes for patients with COVID-19 admitted to Norwegian ICUs' is a national observational study, including patients admitted to a Norwegian ICU between March 2020 and March 2021.
- Conditions
- Covid19, Acute Respiratory Failure, Acute Respiratory Distress Syndrome, Post Intensive Care Unit Syndrome
- Trial name
- NCT04601090
- Testing
- ICU treatment
- Where
- Norway
- Volunteers
- 860 people
- Sponsor
- Oslo University Hospital
Respiratory Failure
Respiratory Care in Intensive Care Unit for Neuromuscular Patients
Retrospective multicentric observational study exploring the population of adult neuromuscular patients presenting a respiratory distress requiring their admission in an Intensive Care Unit (ICU) for ventilatory support.
- Trial name
- NCT02936908
- Testing
- Ventilatory support
- Where
- 4 sites in France
- Volunteers
- 300 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Failure
Hannover Dialysis Outcome Study
Mortality rates of patients with acute kidney injury in the intensive care unit have changed little over the past few decades despite significant advances in supportive care.
- Trial name
- HAND-OUT (NCT00529139)
- Testing
- Standard extended dialysis, Intensified extended dialysis
- Where
- Germany
- Volunteers
- 157 people
- Sponsor
- Hannover Medical School
Esophageal Varicose Veins
Early TIPS in Real Life for Patient Admitted to Intensive Care Unit
Acute esophageal variceal bleeding (AEVB) is a serious complication of cirrhosis, with high morbidity and mortality. The latest European recommendations(1) recommend the early implementation, within 72 hours following esophageal…
- Trial name
- REALYTIPS (NCT04173299)
- Testing
- early tips
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Survival
Adrenal Exhaustion Syndrome in Critically Ill Patients Without Improvement
We study the relationship between patient outcomes and sequential changes of serum cortisol level.
- Trial name
- NCT00674284
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Survival, Intensive Care Unit
Effect of Sinovac on Survival in Intensive Care Unit
Effect of Inactivated COVID-19 Vaccine (Sinovac) on survival in intensive care unit, Single Center Experience
- Trial name
- NCT04956562
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
COVID, Acute Respiratory Distress Syndrome
Impact of Angiotensin II Receptor Blockers Treatment in Patients With COVID 19 (COVID-ARA2)
The actual pandemic infection related to SARS-CoV2 results in viral pneumonitis (COVID-19), that may, in the more severe cases, lead the patients to the intensive care unit (ICU).
- Trial name
- COVID-ARA2 (NCT04337190)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Polytrauma
Comparing Trauma Severity Scores Injury Severity Score "ISS", Rapid Emergency Medicine Score "REMS" and Kampala Trauma Score "KTS"
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading…
- Trial name
- NCT05544773
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assiut University
COPD Exacerbation, ICU
Characteristics and Outcomes of Patients Admitted to ICU for a Severe Acute Exacerbation of COPD.
The objective of this prospective observational study is to describe the epidemiological, clinical and biological characteristics of patients admitted in ICU for a severe acute exacerbation of COPD, and to assess the different…
- Trial name
- COPDregister (NCT06257329)
- Testing
- register
- Where
- 4 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Alexis FERRE
COVID-19 Pneumonia
A Novel Parameter LIT/N That Predicts Survival in COVID-19 ICU Patients
A brisk immune response can clear a pathogen but can cause extensive collateral damage to the host. It is known that coronavirus disease 2019 (COVID-19) infection triggers a multi system inflammatory disorder which can lead to a…
- Trial name
- NCT05520918
- Testing
- the LIT test
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Gazi University
Aged, 80 and Over, Critical Care
Prognostic Score in the Very Old ICU Patients
The two main aims of the study: 1. To investigate the relation of Frailty, Activity of daily life (ADL), Cognitive functions and Co-morbidity on survival at 30 days (and 6 months in a substudy) 2.
- Trial name
- VIP2 (NCT03370692)
- Testing
- Cognitive assesment, Frailty assessment
- Where
- Norway
- Volunteers
- 3,900 people
- Sponsor
- University of Bergen