Clinical trials: IIH - Idiopathic Intracranial Hypertension
Idiopathic Intracranial Hypertension
An RCT of Bariatric Surgery vs a Community Weight Loss Programme for the Sustained Treatment of IIH
Idiopathic intracranial hypertension (IIH) is a condition with an unknown cause or causes. The condition is associated with raised pressure in the brain and can cause disabling daily headaches and loss of sight, which can be…
- Trial name
- IIH:WT (NCT02124486)
- Testing
- Bariatric surgery, Dietetic intervention
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Pediatric Idiopathic Intracranial Hypertension
OCT Imaging of Papilledema in Pediatric Idiopathic Intracranial Hypertension
Longitudinal clinical observation of optic nerve head, using slit lamp fundoscopy, guides therapy in pediatric idiopathic intracranial hypertension (IIH) patients; however, it remains a limited method of producing quantitative…
- Trial name
- NCT02665858
- Testing
- OCT Imaging
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Pseudotumor Cerebri, Cerebrospinal Fluid
Stenting Versus Neurosurgical Treatment of Idiopathic Intracranial Hypertension.
Idiopathic intracranial hypertension (HTICi) is a pathology, affecting young adults with a predominance of women, due to an increase in intracranial pressure, which may be associated with stenosis of the cerebral venous sinuses…
- Conditions
- Pseudotumor Cerebri, Cerebrospinal Fluid, Transverse Sinuses
- Trial name
- HYDROPTIC (NCT05050864)
- Testing
- venous sinus stenting, Neurosurgical internal ventricular shunt
- Where
- France
- Volunteers
- 276 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Chronic Kidney Disease
Disc Edema in Patients With Chronic Kidney Disease
Papilledema is defined as swelling of the optic nerves often due to increased intracranial pressure. When present, it often indicates life-threatening lesions of the brain such as tumors, abscesses, meningitis, encephalitis…
- Trial name
- NCT00769834
- Where
- United States
- Sponsor
- University of Mississippi Medical Center
Idiopathic Intracranial Hypertension
Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment
This study aims to investigate the safety and efficacy of semaglutide in patients with Idiopathic intracranial hypertension.
- Trial name
- NCT06361823
- Testing
- Semaglutide, Low calorie diet
- Volunteers
- 74 people
- Sponsor
- Capital Medical University
Idiopathic Intracranial Hypertension (IIH)
Venous Stenting Evaluation in Patients With Intracranial Hypertension Under Long-term Acetazolamide
This study is aimed at patients suffering from long term intracranial hypertension (caracterized by visual loss, chronic headache and/or tinnitus), receiving acetazolamide for more than 1 year, having inadequate response to…
- Trial name
- DIVEIINLATE (NCT06945848)
- Testing
- Acetazolamide, Stent (Tentos 4F or Precise ProRX)
- Where
- 3 sites in France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Montpellier
Idiopathic Intracranial Hypertension
MR Lymphatic Imaging in Idiopathic Intracranial Hypertention
In the brain and its borders, blood vessels coexist with lymphatic vessels exclusively in the dura mater, the outermost layer of meninges.
- Trial name
- LYMPHIMAGIIH (NCT05762367)
- Testing
- 3T MRI with Gadobutrol injection
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Idiopathic Intracranial Hypertension, Intracranial Pressure Increase
Prospective Ocular Imaging for Intracranial Pressure Evaluation
This is a prospectively recruiting, database development study collecting images and videos of the spontaneous venous pulsation at the back of people's eyes - this is a pulse one can see on examination of the back of the eye…
- Conditions
- Idiopathic Intracranial Hypertension, Intracranial Pressure Increase, Spontaneous Venous Pulsations
- Trial name
- POICCP (NCT06855342)
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Benign Intracranial Hypertension
Diagnostic and Prognostic Biomarkers of Idiopathic Intracranial Hypertension
Idiopathic intracranial hypertension (IIH) is a condition of unknown etiology, primarily affecting overweight females of childbearing age.
- Trial name
- NCT04032379
- Testing
- Standard treatment
- Where
- 2 sites in Denmark
- Volunteers
- 300 people
- Sponsor
- Danish Headache Center
Idiopathic Intracranial Hypertension (IIH)
BMI in Idiopathic Intracranial Hypertension and Its Relationship With the Response to Treatment
1. To establish the correlation between the evolution of the body mass index in benign intracranial hypertension and the response to treatments. 2. To establish the BMI at which this disease occurs. 3.
- Trial name
- NCT06913712
- Testing
- Weight loss without pharmacotherapy
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- University of Valencia
Intracranial Hypertension
Assessment of Venous Drainage in Idiopathic Intracranial Hypertension
Intracranial hypertension (IIH) is a disorder producing a syndrome of increased intracranial pressure secondary to a compressive intracranial lesion or said to be idiopathic.
- Trial name
- HYPERPIC (NCT04115553)
- Testing
- MRI examination, ECG
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Eye Change, Idiopathic Intracranial Hypertension
ICP & Outflow Study
This study aims to investigate the relationship between intracranial pressure (ICP) and aqueous outflow (the flow of the eye's internal fluid out of the eye), in patients with increased intracranial pressure (idiopathic…
- Trial name
- NCT06436820
- Testing
- Lumbar puncture
- Volunteers
- 66 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Idiopathic Intracranial Hypertension (IIH)
Eptinezumab for Chronic Headache in Idiopathic Intracranial Hypertension
The goal of this clinical trial is to learn if eptinezumab can reduce headache frequency and headache-related disability in adults with idiopathic intracranial hypertension (IIH) and chronic headache.
- Trial name
- PRIMA (NCT07645833)
- Testing
- Eptinezumab
- Volunteers
- 96 people
- Sponsor
- Rigmor Højland Jensen
Pseudotumor Cerebri, Cystinosis
The Role of Susceptibility to Thrombosis in the Pseudotumor Cerebri of Nephropathic Cystinosis: A Case-Control Study
This study will examine whether the tendency to have thrombosis, or the formation of blood clots inside blood vessels, has a role in the development of pseudotumor cerebri (PTC).
- Trial name
- NCT00071903
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hydrocephalus, NPH (Normal Pressure Hydrocephalus)
CERTAS Programmable Valve Registry
Post-Market Clinical Follow-up Registry of Patients with CODMAN CERTAS Plus Programmable Valves.
- Conditions
- Hydrocephalus, NPH (Normal Pressure Hydrocephalus), IIH - Idiopathic Intracranial Hypertension
- Trial name
- CERTAS (NCT04207229)
- Testing
- CODMAN CERTAS Programmable Valves
- Where
- 8 sites in Germany, Netherlands
- Volunteers
- 35 people
- Sponsor
- Integra LifeSciences Corporation
IIH - Idiopathic Intracranial Hypertension
Current Treatment Methods of Idiopathic Intracranial Hypertension
Aim of the study : 1. to determine the response to each treatment plan. 2. to determine when to choose specific treatment method. 3. to determine complication of each type of treatment method
- Trial name
- NCT06353412
- Testing
- Lumbar puncture
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hydrocephalus, Idiopathic Intracranial Hypertension
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
This research is being done to determine the accuracy of two noninvasive methods of measuring the pressure of the cerebrospinal fluid (CSF), also known as intracranial pressure or ICP.
- Conditions
- Hydrocephalus, Idiopathic Intracranial Hypertension, Pseudotumor Cerebri
- Trial name
- NCT01863381
- Testing
- Tympanic membrane displacement (TMD), DPOAE
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- LifeBridge Health
Idiopathic Intracranial Hypertension (IIH)
Venous Sinus Stenting for Idiopathic Intracranial Hypertension Refractory to Medical Therapy
Idiopathic Intracranial Hypertension (IIH) is a disease that affects mainly young people, and is associated with headache and loss of vision.
- Trial name
- VSSIIH (NCT01407809)
- Testing
- Venous Sinus Stenting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Idiopathic Intracranial Hypertension (IIH)
Tirzepatide in Idiopathic Intracranial Hypertension Trial
This will be a randomized, double-blind, parallel, placebo-controlled trial of 60 participants. The primary analysis will be a statistical comparison of the estimates of the mean difference in the 12-month change in intracranial…
- Trial name
- TIIHT (NCT07191873)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Idiopathic Intracranial Hypertension
Outcome of Cerebral Venous Sinuses Stenting on Idiopathic Intracranial Hypertension
The aim of the work is to asses the positive effect of stenotic sinus segment stenting on idiopathic intracranial hypertension with headache and papilloedema.
- Trial name
- NCT05308823
- Testing
- Stent
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University