Clinical trials: IL6
Glycogen Depletion
IL-6 Regulation of Energy Stores During Recovery From an Acute Exercise Bout
The aim of the study is to investigate the role of exercise-induced IL-6 in regulating energy stores and energy metabolism during recovery after an acute exercise bout.
- Trial name
- REX-6 (NCT05349149)
- Testing
- Tocilizumab/Actemra® (Roche), Saline 9%
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Helga Ellingsgaard
Renal Insufficiency
Atorvastatin in the Recipient's Kidney Graft From a Living Donor
Renal insufficiency is a priority disease in the health system, which may require renal replacement therapy based on kidney transplantation, which is considered as therapy of choice.
- Trial name
- ATORV15 (NCT02522117)
- Testing
- Atorvastatin
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Appetitive Behavior, Pediatric Obesity
IL-6 in Exercise-Induced Anorexia
This study investigates the effect of high intensity exercise, with and without the inflammation inhibitor, ibuprofen, on plasma levels of IL-6 and other selective biomarkers of inflammation and appetite on food intake and…
- Trial name
- NCT03295968
- Testing
- High Intensity Exercise/Ibuprofen
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Periodontal Disease, Gingivitis and Periodontal Diseases
Salivary Biomarkers in Periodontal Disease Progression
This study aims to evaluate salivary biomarkers associated with bone remodeling during the transition from periodontal health to disease.
- Conditions
- Periodontal Disease, Gingivitis and Periodontal Diseases, Periodontitis
- Trial name
- PERIO-BIO (NCT07661784)
- Testing
- Saliva Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
COVID-19, Cytokine Storm
Fluoxetine to Reduce Intubation and Death After COVID19 Infection
This project will test the efficacy of fluoxetine to prevent serious consequences of COVID-19 infection, especially death. Becoming sick with COVID-19 virus or any other serious respiratory condition is not fun.
- Trial name
- NCT04377308
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toledo Health Science Campus
Anxiety
Biological and Psychological Markers After Intervention in Adults With GAD
This clinical trial inestigates the effects of transcranial direct current stimulation (tDCS) on anxiety symptoms in adult women with clinically relevant anxiety levels.
- Trial name
- AnsitDCS (NCT07116980)
- Testing
- 'Transcranial Direct Current Stimulation - tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obesity, Healthy
IL-6 Regulation of Substrate Metabolism and Influence of Obesity
The aim of the study is to investigate the effects of blocking IL-6 signaling with tocilizumab on lipid, glucose and protein metabolism during rest and exercise in healthy and obese humans.
- Trial name
- NCT03967691
- Testing
- Tocilizumab infusion, Saline 0.9%
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Immune Function, Immunity
Effects of TM02® Supplementation on Immune Function in Children
This randomized, double-blind, placebo-controlled clinical study evaluated the effects of 12 weeks of TM02® supplementation on immune-related outcomes in generally healthy children aged 2 to 12 years.
- Trial name
- NCT07853573
- Testing
- TM02®
- Where
- Malaysia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ligno Biotech Sdn. Bhd.
Meconium Aspiration Syndrome
Interleukin-6 in the Development of Meconium Aspiration Syndrome in Newborn
This trial is intended to assess the serum levels of interleukin-6 as a predictive factor for the occurrence of meconium aspiration syndrome in infants born with MSAF.
- Trial name
- NCT07394322
- Testing
- serum interleukin 6
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Benha University
Major Depressive Disorder
Neutralizing Interleukin (IL)-6
The proposed study aims to establish the feasibility and safety of subcutaneous tocilizumab, a monoclonal antibody (mAb) against interleukin (IL)-6 receptor, in adults with Major Depressive Disorder (MDD) and evidence of…
- Trial name
- NCT07493317
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Periodontal Diseases
YKL-40 and IL-6 Levels in Periodontal Disease
The primer aim of the study was to investigate saliva and gingival crevicular fluid (GCF) YKL-40 and also interleukin-6 (IL-6) levels in chronic periodontitis pathogenesis.
- Trial name
- NCT03507868
- Testing
- Nonsurgical periodontal therapy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zeynep Pinar KELES
Opioid Use
Assessing the Impact of Opioid-Free Anesthesia Using the Modified Mulimix Technique.
The effective management of post-operative pain in the setting of bariatric surgery presents significant hurdles for both anesthesiologists and surgeons.
- Trial name
- Mulimi (NCT06216210)
- Testing
- opioid-FREE anesthesia., opioid-CONTAINING anesthesia.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zulekha Hospitals
Lumbar Posterior Decompression
Thoracolumbal Interfascial Plane Block Versus Erector Spinae Plane Block for Lumbar Posterior Decompression Stabilization
This study aimed to found out The Comparison Of Perioperative Analgesia Effectiveness Between Thoracolumbal Interfascial Plane Block with Erector Spinae Plane Block In Lumbar Posterior Decompression and Stabilization.
- Trial name
- NCT04951024
- Testing
- Thoracolumbar interfacial plane (TLIP) Block, Erector Spinae Plane (ESP) Block
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Obesity, Periodontitis
Chemerin and Interleukin-6 Levels of Gingival Crevicular Fluid in Obese Individuals Following Periodontal Treatment
The objective in this case-control intervention study, therefore, was to explore the effect of nonsurgical periodontal therapy on the GCF levels of chemerin and IL-6 in patients with chronic periodontitis in order to determine…
- Trial name
- NCT02660814
- Testing
- Non-surgical periodontal treatment, Gingival crevicular fluid collection
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Umut BALLI
Endometrial Receptivity and Success Rate of IVF
Pilot Study on Molecular Quantitation and Sequencing of Endometrial Cytokines Gene Expression and Their Effect on the Outcome of In-vitro Fertilization (IVF) Cycle
Pilot study on molecular quantitation and sequencing of endometrial cytokines gene expression and their effect on the outcome of in-vitro fertilization (IVF) Cycle
- Trial name
- NCT01809509
- Testing
- Endometrial biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Damage, Athletic Performance
The Combined Effects of Cordyceps and Fartlek Training on Muscle Recovery and Bone Health in Soccer Players
Purpose of the Study:This study aims to evaluate the effectiveness of combining Cordyceps supplementation and fartlek training as a recovery and performance enhancement strategy for soccer players.
- Conditions
- Muscle Damage, Athletic Performance, Oxidative Stress, Inflammation
- Trial name
- COR-FAST (NCT07726979)
- Testing
- Fartlek Training Program, Cordyceps sinensis Supplementation
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Metabolic Syndrome, Overweight
Systematic Review and Meta-analysis of the Differential Effects of DHA and EPA on Inflammation
According to the World Health Organization, cardiovascular diseases (CVDs) are the number 1 cause of death globally. Systemic and local tissue inflammation is now recognized as a key etiological process leading to CVD.
- Conditions
- Metabolic Syndrome, Overweight, Obesity, Chronic Inflammation
- Trial name
- NCT03520556
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Laval University
Infection
Biological Markers for the Diagnosis of Central Nervous System Infective Diseases
Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse.
- Trial name
- NCT02278016
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Oxidative Stress, Inflammation
PsP Ganoderma Lucidum Supplementation and Biomarker Changes in Smokers
The goal of this randomized controlled clinical trial is to evaluate whether polysaccharide peptide (PsP) supplementation from Ganoderma lucidum can modulate biomarkers of oxidative stress, inflammation, nicotine exposure, and…
- Conditions
- Oxidative Stress, Inflammation, Cigarette Smoking
- Trial name
- PSPGL (NCT07316400)
- Testing
- PsP
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Brawijaya
Influenza, Vaccine Reaction
Effectiveness of Trivalent Influenza Vaccine (TIV) in Type 2 Diabetes Mellitus (T2DM) Patients With and Without Complications of Chronic Kidney Disease (CKD)
This study assesses the effectiveness of the seasonal flu vaccine in individuals with Type 2 Diabetes Mellitus (T2DM) with and without Chronic Kidney Disease (CKD), as well as in healthy individuals.
- Conditions
- Influenza, Vaccine Reaction, Diabetes Mellitus, Chronic Kidney Diseases
- Trial name
- NCT06252051
- Testing
- Trivalent Influenza Vaccine
- Where
- Indonesia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran