Clinical trials: IMAGE
Branch Atheromatous Disease, Acute Ischemic Stroke
Early Identification and Diagnosis of BAD-related Stroke
Branch atheromatous disease (BAD)-related stroke is an important subtype of acute ischemic stroke involving penetrating arteries and is associated with early neurological deterioration.
- Conditions
- Branch Atheromatous Disease, Acute Ischemic Stroke, Cerebral Infarction
- Trial name
- SMART-BAD (NCT07693816)
- Testing
- Multisource clinical-imaging artificial intelligence diagnostic assessment
- Where
- 11 sites in China
- Volunteers
- 1,602 people
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation
Cartomerge Versus NavX Fusion in Catheter Ablation of Atrial Fibrillation
Comparison of Two Strategies for Catheter Ablation of Atrial Fibrillation - a comparison of ablation guided by Cartomerge and NavX Fusion. 3D mapping systems are widely used in catheter ablation of AF.
- Trial name
- CAVERN (NCT01432743)
- Testing
- NavX Fusion, Cartomerge
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Barts & The London NHS Trust
Stereoscopic Vision
Subjective Image Quality in Stereoscopic Image Modifications
Humans attain binocular vision from the two retinal images of both eyes through a series of sensory and motor processes that culminate in the perception of stereoscopic depth.
- Trial name
- Stereopsis (NCT01624415)
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alcoholism
Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence
Background: This study is being done to examine the role of a chemical GABA in the brain of alcohol dependent patients. GABA is the chief inhibitory neurotransmitter in the central nervous system.
- Trial name
- NCT01904487
- Testing
- [11C]flumazenil, Tiagabine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Depression
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
Background: Major depressive disorder (MDD) is a psychiatric condition. People with MDD have occasional bouts of depressive symptoms; these bouts are called major depressive episodes (MDEs).
- Trial name
- NCT05703685
- Testing
- Lung scan, Apremilast, 18F-PF-06445974
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Aortic Valve Stenosis
Aortic Stenosis Pre-Transcatheter Aortic Valve Replacement (TAVR) Procedure CT Scan
The purpose of this study is to evaluate contrast media volume, safety and 30-day outcome of patients after a computed tomography (CT) scan.
- Trial name
- NCT01843426
- Testing
- Low-volume, low-concentration contrast (iodixanol - Visipaque 270) CT scan
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Prostate Cancer
Evaluation of Clarity Ultrasound Guidance for Prostate Therapy
Radiotherapy (RT) is an important treatment for prostate cancer with over 10,000 men receiving RT per year in the UK. Prostate RT aims to deliver radiation dose to the prostate to kill cancer cells whilst minimizing the dose…
- Trial name
- Clarity-Pro (NCT02388308)
- Testing
- Clarity ultrasound
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Body Image Disturbance, Medication Adherence
Body Image and Self-Care in HIV-Infected MSM
The purpose of this study is to develop and test counseling strategies for men who have sex with men (MSM) who are living with HIV and are experiencing body dissatisfaction.
- Trial name
- BUILD (NCT01817621)
- Testing
- Experimental Intervention, TAU
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease (AD)
Generation of Synthetic [18F]FDG PET From Early-Phase Amyloid PET in Alzheimer's Disease
This study aims to test a new artificial intelligence (AI) method to create brain scan images without needing an extra scan. Currently, patients with memory problems often undergo two types of PET scans (Amyloid PET and FDG PET)…
- Trial name
- NCT07431255
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- IRCCS San Raffaele
Lung Nodules
DeepPriorCBCT for Low Dose Lung CBCT Reconstruction
The goal of this clinical trial is to learn if the DeepPriorCBCT model ensure high-quality CBCT image while reducing CBCT radiation dose.
- Trial name
- NCT07035977
- Testing
- Participants will receive a 1/6 views undersampling lung CBCT scan.
- Where
- 5 sites in China
- Volunteers
- 138 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Prostate Cancer, Radiotherapy Side Effects
Using Breath, Cell Free DNA and Image Analysis to PRedIct Normal TissUe and Tumour Response During Prostate Cancer SBRT
Personalisation of radiotherapy dose based on real-time assessments of normal tissue and tumour response would maximise cure and minimise treatment related toxicity.
- Conditions
- Prostate Cancer, Radiotherapy Side Effects, Volatile Organic Compounds, DNA Damage
- Trial name
- PRINToUT (NCT04081428)
- Testing
- Stereotactic Body Radiotherapy
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS Lothian
Coronary Artery Disease
RADIQAL Study (Radiation Dose and Image Quality Trial)
The Azurion R4.0 is developed by Philips Medical Systems Nederland B.V., a Philips Healthcare company. The Azurion is an interventional X-ray system which is used for live X-ray imaging during invasive cardiac procedures.
- Trial name
- RADIQAL (NCT06944509)
- Testing
- treatment with the Azurion system with Xres5, Azurion with Clairy IQ
- Where
- 6 sites in United States, Czechia and 2 more
- Volunteers
- 824 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Aortic Aneurysm
Dual Energy CT Urography With Reduced Iodinated Contrast
The goal of this study is to validate that Dual Energy CT (DECT) urography when performed with a 50% reduction in iodinated contrast dose results in a CT exam with equal or better image quality and equal or better diagnostic…
- Trial name
- NCT02283307
- Testing
- Reduced contrast DECT scan, Standard contrast SECT scan
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Washington
Ischemic Heart Disease
Dose Optimization for Rubidium PET Imaging in Patients With Known or Suspected Ischemic Heart Disease
Selection of the appropriate administered activity for each patient's body habitus is very important to obtain diagnostic image quality.
- Trial name
- RUBY-DOSE (NCT05037799)
- Testing
- Rb-82 Radioisotope
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Structural Heart Disease
NHLBI-Emory Advanced Cardiac CT Reconstruction
Background: Doctors use computed tomography (CT) to get detailed pictures of the heart. CT uses x-rays to gather raw data. Computers assemble this data to make the images doctors look at.
- Trial name
- NCT05372627
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Intestinal Abnormalities
Diagnosis of Intestinal Motility by Image Analysis Using Capsule Endoscopy
Conventional intestinal manometry is the current gold standard for the evaluation of intestinal motility, and identifies patterns of intestinal dysmotility.
- Trial name
- NCT01085513
- Testing
- PillCam SB2
- Where
- 6 sites in United States, Belgium and 3 more
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Retinal Disease
P200TxE Diseased Eye Image Collection
The primary objective is to collect images on the P200TxE device in diseased eyes.
- Trial name
- NCT06269666
- Testing
- P200TxE
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Optos, PLC
Migraine
Real-world Impact of Erenumab on Sick-leaves, Health Care Resource Use and Comorbidities.
This was a retrospective registry-based study utilizing data collected in association with clinical care of patients. All data was stored in electronic health records at Terveystalo data base, and no patients were contacted for…
- Trial name
- NCT05375097
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Novartis Pharmaceuticals
Heart Failure
IMAGE-HF Project I-C: Computed Tomographic Coronary Angiography for Heart Failure Patients
Background: The prevalence of heart failure (HF) is rapidly rising in industrialized and developing countries. Though invasive coronary angiography (ICA) remains the gold standard for anatomical assessment of coronary arteries…
- Trial name
- CTA-HF (NCT01283659)
- Testing
- Standard Imaging, Advanced Imaging
- Where
- 15 sites in Canada, Finland
- Volunteers
- 253 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Diastasis Recti And Weakness Of The Linea Alba
The Effect of Conservative Interventions on the Signs and Symptoms of Diastasis Recti
The purpose of this study is to determine the effect of two different physiotherapeutic interventions (exercise therapy and/or abdominal binding) on the signs and symptoms of diastasis recti in post-partum women.
- Trial name
- NCT02268110
- Testing
- Exercise therapy, Abdominal binding
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Queen's University
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