Clinical trials: IMMUNONUTRITION
IMMUNONUTRITION
IMMUNONUTRITION IN FAST-TRACK SURGERY
Compare the results in terms of morbidity, mortality and hospitalization among patients with input from immunonutrients and patients with enteral nutrition intake of high calorie and high protein undergoing colorectal surgery…
- Trial name
- NCT02393976
- Testing
- IMMUNONUTRITION, STANDART NUTRITION
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital General Universitario Elche
Colorectal Cancer
Preoperative Immunonutrition in Normonourished Patients Undergoing Fast-track Laparoscopic Colorectal Surgery
Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after gastrointestinal surgery. More specifically, it seems to be beneficial also in colorectal cancer surgery.
- Trial name
- NCT04692545
- Testing
- Immunonutrition
- Volunteers
- 173 people
- Sponsor
- University of Rome Tor Vergata
Colon Cancer, Nutrition Aspect of Cancer
Changes in Inflammatory Response After Immunonutrition Compared to Standard Nutrition in Colorectal Cancer Tissue
It is Randomized Controlled Trial, in which investigators will estimate the impact of the use of immunonutrition support compared to standard nutritional support in the preoperative period in patients with colorectal cancer.
- Trial name
- NCT04732442
- Testing
- Immunonutrition, Standard Oral Nutritional Support
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Immunonutrition, Surgical Outcome
Perioperative Supplementation With Immunonutrition and Its Impact on Surgical Outcome and Pain in Oral Cavity or Mandibular Tumours
The aim of this study was to investigate the effect of adding omega 3 and dipeptiven to standard feeding in head and neck patients who will undergo oral cavity tumour resection or mandibular tumour resection (immunonutrrition…
- Conditions
- Immunonutrition, Surgical Outcome, Pain, Oral Cavity
- Trial name
- NCT06339372
- Testing
- Standard feeding, Omega 3 and dipeptiven
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Cairo University
Fibromyalgia
Melatonin and Immunonutrition for Pain Relief in Fibromyalgia
Fibromyalgia (FMS) is characterized by chronic musculoskeletal pain, sleep disturbances, and fatigue. It is not entirely clear how Bcomplex vitamins affect the human pain system, while at the same time there have been approaches…
- Trial name
- NCT07863232
- Testing
- Melatonin 1mg and intravenous B-complex vitamin drip
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Thoracic Surgery, Cardiac Surgery
Immunonutrition in Cardiac Surgery
Effect of two preoperative oral immune-enhancing nutritional supplements in patients at high risk of infection after cardiac surgery: a randomized placebo-controlled study.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Cardiopulmonary Bypass
- Trial name
- NCT00247793
- Testing
- Oral Impact (preoperative enteral nutritional supplement)
- Where
- Netherlands
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Bladder Cancer, Interstitial Cystitis
The Role of Preoperative Immunonutrition on Morbidity and Immune Response After Cystectomy (INCyst Trial)
The goal of this clinical trial research study is to evaluate the impact of preoperative oral immunonutrition (IN) on post-operative complications in patients undergoing a cystectomy.
- Conditions
- Bladder Cancer, Interstitial Cystitis, Painful Bladder Syndrome, Neurogenic Bladder
- Trial name
- INCyst (NCT05726786)
- Testing
- Immunonutrition
- Where
- 4 sites in Switzerland
- Volunteers
- 232 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Wound Complication, Wound Heal
Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction
This study is designed to test the following hypothesis: patients undergoing immediate alloplastic and autologous breast reconstruction following mastectomy that receive preoperative immunonutrition will experience a reduction in…
- Conditions
- Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection
- Trial name
- NCT03764943
- Testing
- Impact Advanced Recovery
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Wisconsin, Madison
Upper GI Cancer
Immunonutrition for Surgical Prehabilitation of Patients With Upper GI Cancer
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after upper GI surgery.
- Trial name
- IMNUTPREH-UGIC (NCT07884214)
- Testing
- Oral nutritional supplements with immunonutrition (enriched with arginine, nucleotides, vitamin D and omega-3-fatty acid), Standart of care
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Head and Neck Cancer
Immunonutrition Supplementation in Head and Neck Cancer Patients Undergoing Cancer Treatment Study
This is a prospective, randomized, open-label intervention study to evaluate the effectiveness of immunonutrition supplementation in head and neck cancer (HNC) patients during cancer treatment.
- Trial name
- HaNIS (NCT05526040)
- Testing
- Immunonutrient-enriched oral nutrition supplementation, Standard medical nutrition therapy
- Where
- 2 sites in Malaysia
- Volunteers
- 116 people
- Sponsor
- University of Malaya
Esophageal Neoplasms
Effects of Preoperative Enteral Immunonutrition for Esophageal Cancer Patients Given Neoadjuvant Chemoradiotherapy
This randomized controlled trial will evaluate the effects of preoperative enteral immunonutrition in esophageal cancer patients undergoing neoadjuvant therapy.
- Trial name
- POINT (NCT04513418)
- Testing
- Preoperative immunonutrition
- Where
- 6 sites in China
- Volunteers
- 244 people
- Sponsor
- Hecheng Li M.D., Ph.D
Undernutrition
The Role of Preoperative Oral Immunonutrition in Major Vascular Surgery
The role of preoperative oral immunonutrition in major vascular surgery. The mean purpose of this study was to determine the prevalence of post-operative infection complications after major vascular surgery in group of patients…
- Trial name
- NCT00559520
- Testing
- Impact, Oral Impact
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Gastrointestinal Cancer
Effects of Immunonutrition (Impact Oral®) in Patients Undergoing Surgery for Gastrointestinal Cancer
This study will evaluate the efficacy and safety of Impact Oral in Patients undergoing Surgery for Gastrointestinal Cancer, half of the participants will receive Impact Oral nutrition therapy, the other half will receive Enteral…
- Trial name
- NCT03665714
- Testing
- Impact Oral, Enteral Nutrition Emulsion(TPF-T)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Société des Produits Nestlé (SPN)
Cardiac Function
Preoperative Immunonutrition and Cardiac Patients
With the progress of cardiac surgery, the indication of cardiac valve replacement has been extended to include severely ill patients, even those with cardiac cachexia caused by long-standing mitral valve disease.
- Trial name
- NCT03445221
- Testing
- IV Immunonutrition, Conventional Diet
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Bile Duct Cancer
Effects of Preoperative Immunonutrition in Patients Undergoing Hepatectomy
The purpose of this study is to determine whether preoperative immunonutrition is effective on infectious complication and Th1/Th2 differentiation in patients with major hepatectomy.
- Trial name
- NCT01256047
- Testing
- Oral IMPACT
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Chiba University
Colorectal Neoplasms
Effect of Preoperative Immunonutrition Versus Standard Oral Nutrition in Patient Undergoing Colorectal Surgery.
This is a randomised controlled clinical trial . The investigators aim to compare the effects of preoperative immune modulating enteral nutrition and standard oral nutrition supplement on clinical outcomes of the patients undergo…
- Trial name
- NCT06128798
- Testing
- Oral Impact, Nutren Optimum
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- Hospital Universiti Sains Malaysia
Gastrointestinal Cancer
Effects of 3 Day Preoperative Immunonutrition in Well-nourished Patients With Gastrointestinal (GI) Cancer Undergoing Surgery
Major surgery is still associated with a high rate of postoperative morbidity despite improved techniques in surgical management.
- Trial name
- IPOD-3 (NCT01023412)
- Testing
- Immunonutrition
- Where
- 6 sites in Switzerland
- Volunteers
- 107 people
- Sponsor
- Société des Produits Nestlé (SPN)
Pancreatic Cancer
Preoperative Oral Immunonutrition for Patients With Pancreatic Cancer Undergoing Elective Surgery - Effect on Complications and Length of Hospital Stay
The purpose of this study is to investigate the effect of preoperative immunonutrition on complications and length of hospital stay in patients with pancreatic cancer undergoing elective surgery.
- Trial name
- NCT01789073
- Testing
- Oral Impact, Nestlé Health Science
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- University of Copenhagen
Prebiotics Effect
Prebiotics Change Microflora and Decrease LPS
The purpose of the present study was to establish the prebiotic effect of a new xylo-oligosaccharides (XOS) and of an inulin-and-XOS mixture (INU-XOS) and to determine their effect on endotoxaemia (lipopolysaccharides (LPS)) and…
- Trial name
- PIB (NCT02287844)
- Testing
- XOS, INU-XOS
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Pancreaticoduodenectomy
Effects of Immunonutrition in Patients Undergoing Pancreaticoduodenectomy
The purpose of this study is to determine whether immunonutrition is effective on surgical site infection and Th1/Th2/Th17 differentiation in patients undergoing pancreaticoduodenectomy
- Trial name
- NCT00668876
- Testing
- Oral IMPACT, Parenteral nutrition
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- Chiba University