Clinical trials: IMPLANTATION
Periimplantitis, Peri-implant Mucositis
The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy
Peri-implantitis is defined as inflammation in the mucosa surrounding an oral implant with loss of supporting bone. The goals of peri-implantitis treatment are to resolve inflammation and to arrest the progression of disease.
- Trial name
- NCT03421717
- Testing
- Chitosan brush
- Volunteers
- 46 people
- Sponsor
- University of Oslo
Infections, Quality of Life
Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.
The goal of this clinical trial is to learn whether showering with surgical drain tubes in place after first stage breast reconstruction causes increased risk of infection.
- Trial name
- NCT05846438
- Testing
- Showering 48 hours after surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Prosthesis User, Digitalism
Precision of Three Different Scanbodies Used for Direct Digitalization Technique
The goal of this clinical trials to evaluate precision of different scanbodies in same participant group. The main guestion it aim to answer is: 1.
- Trial name
- NCT05790148
- Testing
- 3Shape
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Total Knee Arthroplasty, Osteo Arthritis Knee
In Vivo Kinematics for Subjects Implanted With Klassic Total Knee Arthroplasty (TKA)
In vivo knee kinematics will be assessed for 20 subjects that have been implanted with a Total Joint Orthopedics Klassic knee system by Dr.
- Conditions
- Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Implant, Knee Injuries
- Trial name
- TKA (NCT04113785)
- Testing
- Klassic Knee System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Tennessee, Knoxville
Bone Graft
Acellular Collagen Matrix as a Tool to Obtain Wound Closure Following a Guided Bone Regeneration Procedure
Guided bone regeneration (GBR) is a procedure used to increase the amount of bone volume in the jaw before placing a dental implant.
- Trial name
- NCT06871735
- Testing
- Acellular matrix, Surgical closure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Bone Loss, Bone Resorption
Socket Shield Technique Versus Early Implant Placement With Contour Augmentation
comparing socket shield technique with early implant placement with contour augmentation in preserving the bone contour
- Trial name
- NCT05261334
- Testing
- contour augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Iman Abd-ElWahab Radi, PhD
Cochlear Function Disorder
Cochlear Implantation Experience
Evaluating the effectiveness and outcomes of cochlear implants in individuals with hearing loss,identifying common complications or risks associated with cochlear implantation, including device failure, surgical complications, or…
- Trial name
- NCT06896864
- Testing
- cochlear implantation
- Volunteers
- 150 people
- Sponsor
- Assiut University
Surface Finish
Influence of Different Zirconia Surface Treatments on Biofilm Formation
The aim is to test the influence of surface finish on biofilm formation on the transmucosal part of zirconia implants in an in vivo study.
- Trial name
- Biofilm2020 (NCT04181099)
- Testing
- Implant neck surface
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Basel
Erectile Dysfunction
Penile Lengthening Pre-Penile Prosthesis Implantation
This study is intended to utilize a novel, class I (ie. lowest risk, clinical studies not required) medical device to determine whether penile length can be increased in men prior to undergoing a penile prosthesis implantation…
- Trial name
- NCT03500406
- Testing
- RestoreX, Control
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Congenital Hearing Loss, Bilateral Cochlear Implants
Investigating the Neural Oscillatory Features for Limited Access to Oral Language in Deaf Children With Early Bilateral Cochlear Implantation
Children with severe-to-profound congenital hearing loss often experience significant language development challenges. While cochlear implants (CIs) can restore auditory input, outcomes vary widely, even among those who receive…
- Trial name
- ICO (NCT07739433)
- Volunteers
- 150 people
- Sponsor
- Institut Pasteur
Cataract, Anterior Chamber Inflammation
Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery
Phase 2b trial evaluating the safety and efficacy of EGP-437, versus placebo using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with implantation of a monofocal posterior chamber…
- Conditions
- Cataract, Anterior Chamber Inflammation, Pain, Postoperative
- Trial name
- NCT03180255
- Testing
- Dexamethasone phosphate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Breast Implant; Complications, Breast Expansion Prosthesis
Characterization of Capsule Inflammation in Patients Exposed to Silicone Breast Implants
The use of breast implants, both in cosmetic and restorative surgery, is common. It is a device consisting of a silicone elastomer envelope and the container of which may be silicone gel or saline.
- Trial name
- INFLAMA (NCT06414785)
- Testing
- analysis of samples of periprosthetic capsules taken during breast implant change procedure
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Transcatheter Aortic Valve Replacemen, Angiotensin-Converting Enzyme Inhibitors
Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI)
The investigators aim to demonstrate that ramipril after transcatheter aortic valve implantation has benefits in terms of prognosis, cardiovascular events and ventricular remodeling (MRI).
- Trial name
- RASTAVI (NCT03201185)
- Testing
- Ramipril
- Where
- Spain
- Volunteers
- 194 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Peri-implant Mucositis, Dental Implant Failed
Soft and Hard Tissues Evaluation Around Immediately Placed New Implant Design
patients were randomly divided into Maxi-Z plus dental implant group versus Maxi-Z implant group
- Trial name
- NCT04905758
- Testing
- platform switching, platform amtching
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Tachycardia, Diabetes Mellitus
Multicenter Automatic Defibrillator Implantation Trial With Subcutaneous Implantable Cardioverter Defibrillator
The MADIT S-ICD trial was designed to evaluate if subjects with a prior myocardial infarction, diabetes mellitus and a relatively preserved ejection fraction of 36-50% will have a survival benefit from receiving a subcutaneous…
- Conditions
- Tachycardia, Diabetes Mellitus, Cardiovascular Disease
- Trial name
- MADIT S-ICD (NCT02787785)
- Testing
- Subcutaneous Implantable Cardioverter Defibrillator
- Where
- 49 sites in United States, Germany and 5 more
- Volunteers
- 40 people
- Sponsor
- Boston Scientific Corporation
Aortic Valve Stenosis
Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI)
Transcatheter Aortic Valve Implantation (TAVI) is now the method of choice to treat aortic stenosis in old and frail patients. Antiplatelet therapy must be associated for the procedure and during few weeks after implantation in…
- Trial name
- TICTAVI (NCT02817789)
- Testing
- Ticagrelor alone, Combination lysine acetylsalicylate - clopidogrel
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Breast Cancer, Breast Carcinoma in Situ
Immediate Breast Reconstruction With Acellular Dermal Matrix
The aim of this study is to contribute to the knowledge regarding immediate implant-based BR by investigating whether the one-stage technique with ADM is superior to the two-stage expander to implant technique.
- Conditions
- Breast Cancer, Breast Carcinoma in Situ, Mammaplasty, Acellular Dermis
- Trial name
- NCT04209010
- Testing
- one-stage technique
- Volunteers
- 44 people
- Sponsor
- Aarhus University Hospital
Horizontal Alveolar Ridge Deficiency
Autobone and Bioactive Glass With Ridge Splitting
Objective: To compare the use of autogenous bone graft versus autogenous bone graft mixed with bioactive glass bone graft in the treatment of maxillary anterior horizontal bone defects by ridge splitting technique combined with…
- Trial name
- NCT04814160
- Testing
- mixture of bioactive glass and autogenous bone graft, autogenous bone graft
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Osteochondritis Dissecans, Osteoarthritis
ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee
ACI-C versus AMIC: A controlled randomized trial comparing Autologous Chondrocyte Implantation ( ACI) and Autologous Matrix Induced Chondrogenesis (AMIC) for repair of cartilage defects in the knee.
- Conditions
- Osteochondritis Dissecans, Osteoarthritis, Cartilage Injury, Osteonecrosis
- Trial name
- NCT01458782
- Testing
- Treatment of cartilage defects in the knee
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- University Hospital of North Norway
Jaw, Edentulous, Partially, Dental Implant Failed
Survival and Success Rates of 6mm Implants With a Micro-rough Surface After 4.5 - 18.2 Years in Function
In this retrospective study, approximately 60 patients treated with 6mm short implants (Straumann, SLA (sandblasted, large-grit, acid-etched surface), SLActive (sandblasted, large-grit, acid-etched, hydrophilic surface), 4.1 or…
- Conditions
- Jaw, Edentulous, Partially, Dental Implant Failed, Implant Complication
- Trial name
- NCT04017026
- Testing
- Implantation
- Where
- Switzerland
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Bern