Clinical trials: IMPLANTATION
Dental Implant, Edentulous Alveolar Ridge
Clinical and Radiographic Comparison of Two Implant-Abutment Connections
The aim of this clinical study is to evaluate two different implant-abutment connection design on preserves gingiva and bone health in the long term.
- Trial name
- NCT07889882
- Testing
- N1 Dental implant placement + N1 abutment, Nobel active Implant placement + on1 abutment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kutahya Health Sciences University
Accelerated Orthodontic Tooth Movement
Comparing MOP, Prostaglandin E1, and Calcitriol to Accelerate Orthodontic Tooth Movement
This study will compare the effects of MOP (micro-osteoperforation), prostaglandin E1, and calcitriol on the rate of orthodontic tooth movement.
- Trial name
- acceleration (NCT07842120)
- Testing
- PGE₁ (pharmacological) • Agent: Prostaglandin E1, Calcitriol (1,25-(OH)₂D₃) local injection • Agent: Calcitriol (1,25-(OH)₂D₃) Vitamin D3, microosteoperforation MOP (surgical)
- Where
- 2 sites in Iraq
- Volunteers
- 60 people
- Sponsor
- Ghufran Dhari Awad
Coronary Artery Disease, High Bleeding Risk Patients
PaneLux PTCA : Proposing an Alternative Treatment to patiEnts for Whom DES Implantation is Not Indicated, Thanks to Pantera LUX Drug Eluting Balloon
The propose of this study is to demonstrate, whenever using Drug Eluting Stent is not possible, the clinical security at 12 months, of the combinaison Bare Metal Stent plus Drug Eluting Balloon.
- Trial name
- PaneLux PTCA (NCT01930903)
- Testing
- Pantera Lux Drug Eluting Balloon
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Biotronik France
Implant Therapy
Clinical and Radiographic Evaluation of Local Melatonin Application on Osseointegration of Immediate Mandibular Implants
Clinical and Radiographic Evaluation of Local Application of Melatonin on Osseointegration of Immediate Dental Implants for Mandibular Single Rooted Teeth: A Randomized Controlled Study
- Trial name
- NCT07374523
- Testing
- Melatonin gel, Control
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Suez Canal University
Dental Implant
Accuracy of Dental Implant Placement Using a Collaborative Surgery Robot
For free hand dental implant placement, a key difficulty is to accurately control the position. Improving precision of dental implant placement is considered important for safety and efficacy of tooth replacement with dental…
- Trial name
- NCT05919862
- Testing
- Robot system, Freehand surgery
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Aortic Valve Stenosis
Sentinel Low Risk Registry
This registry is designed to quantify embolic debris capture rate in patients at low surgical risk treated with the Sentinel System during TAVI.
- Trial name
- NCT04131127
- Testing
- Sentinel Device
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- CVPath Institute Inc.
Focus Whether After Implant Pre-AICD Video Was Helpful
LifeSkills Video Training in Patients About to Receive an Automatic Implantable Cardioverter-Defibrillator (AICD)
The purpose of this trial was to develop the initial sections of a video/DVD cassette that provided guidance about mastering stressful situations for patients who had been informed that they need an implantable…
- Trial name
- AICD (NCT01686490)
- Testing
- Video/workbook for patients about to receive an AICD, LiveSkills Video/Workbook for patients about to receive an AICD
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Williams LifeSkills
Atrial Fibrillation, Stroke
Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants
This study will assess the safety and performance of the Vine™ Embolic Protection System (embolic filtering device) in atrial fibrillation (AF) patients on top of oral anticoagulants (OAC), and remain at high risk for stroke…
- Trial name
- CAPTURE2 (NCT03892824)
- Testing
- Vine™ Embolic Protection System
- Where
- 17 sites in Belgium, Czechia and 6 more
- Volunteers
- 100 people
- Sponsor
- Javelin Medical
Dental Implant
Socket Shield With Immediate Implant Stability
To evaluate socket shield technique either placing implant in direct contact to tooth fragment versus gap created between the tooth and implant.
- Trial name
- NCT04882761
- Testing
- Dental implant
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Ain Shams University
Dental Implants
A Triple-blinded Non-inferiority Multicentre Randomized Controlled Trial Comparing Hybrid and Fully Etched Implants P1
The goal of this randomized controlled clinical trial is to compare implant stability between hybrid implants and fully rough implants in partially edentulous patients.
- Trial name
- NCT06100120
- Testing
- Implant placement
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Milan
Stable Angina, Coronary Stenosis
Optical Coherence Tomography to Investigate FFR-Guided DEB-only Elective Coronary Angioplasty
We aimed to evaluate feasibility and the 6-month angiographic and OCT results of FFR - guided use of paclitaxel-eluting balloons (Sequent Please™, B Braun) with provisional bare metal stenting for elective PCI of de novo coronary…
- Trial name
- OCTOPUS-2 (NCT02120859)
- Testing
- FFR - guided DEB angioplasty, Provisional bare metal stenting
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Jena
Meniscectomy, Osteoarthritis
Verifying the Effectiveness of the NUsurface® System
The NUsurface® Meniscus Implant Randomized Study is a multi-center, prospective randomized, interventional clinical trial to test the hypothesis that the NUsurface implant is superior to the non-surgical standard of care in…
- Trial name
- VENUS (NCT02108496)
- Testing
- NUsurface® Meniscus Implant, NSAID's and Non-surgical Treatment Options, Intra-Articular Injections with Corticosteroids
- Where
- 9 sites in United States
- Volunteers
- 337 people
- Sponsor
- Phoenix Kinetics
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Horizontal Ridge Augmentation With Simultaneous Implant Placement Using Autogenous Ramus Grafts
This retrospective observational study evaluated the clinical outcomes of simultaneous implant placement with horizontal ridge augmentation using autogenous mandibular ramus block grafts.
- Trial name
- NCT07209618
- Testing
- utogenous mandibular ramus block grafting with simultaneous dental implant placement, Autogenous mandibular ramus block graft with simultaneous implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Akdeniz University
Diabetic Macular Edema
Ranibizumab vs Dexamethasone Implant in Vitrectomized Eyes With Diabetic Macular Edema
Vitrectomy is required for removal of vitreous hemorrhage or retinal traction tissue in some patients with proliferative diabetic retinopathy. Post-vitrectomy macular edema may occur in these diabetic patients.
- Trial name
- NCT04089605
- Testing
- dexamethasone implant, Ranibizumab
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Far Eastern Memorial Hospital
Cochlear Implant Users
This Clinical Investigation Assesses the Safety and Performance of a New Beamformer for MED-EL Cochlear Implant Recipients.
Cochlear implants help individuals with hearing loss by delivering electrical signals directly to the auditory nerve, bypassing damaged parts of the ear.
- Trial name
- M11S3 (NCT07213505)
- Testing
- Testing new front-end features
- Where
- 2 sites in Austria
- Volunteers
- 40 people
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Cochlear Implant, Sensorineural Hearing Loss
Anatomy-Based Fitting in Bimodal Cochlear Implant Users
The purpose of the study is to investigate the effect of an anatomy-based frequency distribution in comparison to a default frequency distribution in bimodal CI patients, i.e.
- Conditions
- Cochlear Implant, Sensorineural Hearing Loss, Hearing Aid
- Trial name
- NCT07691853
- Testing
- Anatomy-based fitting, Default fitting
- Where
- 2 sites in Belgium
- Volunteers
- 25 people
- Sponsor
- Universitair Ziekenhuis Brussel
Cataract, Pediatric Cataract
AquaLase Capsule Wash for Pediatric Eyes
To determine whether AquaLase capsule wash reduces posterior capsule opacification (PCO) in pediatric eyes.
- Trial name
- NCT00756327
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Left Atrial Appendage Occlusion
Use of Intracardiac Echocardiography or Left Atrial Appendage Radiography to Guide Implantation of a Left Atrial Appendage Occlusion Device
A total of 40 patients with atrial fibrillation were scheduled to receive left atrial appendage occlusion, which were divided into two groups.
- Trial name
- NCT04524741
- Testing
- intracardiac echocardiography
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Second Hospital of Hebei Medical University
Keratoconus
Corneal Stroma Implantation for the Treatment of Keratoconus
The purpose of this study is to determine whether corneal stroma implantation is effective in the treatment of keratoconus.
- Trial name
- NCT03229239
- Testing
- corneal stroma implantation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shandong Eye Hospital
Cervical Degenerative Disease
Improving Cervical Spine Alignment and Intervertebral Foramen Expansion Using a Novel Distally Expanding Cervical Facet Implant for Cervical Degenerative Disease
Cervical degenerative disease (CDD) resulting in myelopathy represents the commonest disease affecting the spinal cord in adults. Cervical radiculopathy can be associated with myelopathy or occurs alone.
- Trial name
- CeLFI (NCT07142174)
- Testing
- cervical facet implant will be introduced into the cervical levels that were mobile on flexion-extension x-ray and exhibited foramen stenosis or spondylolisthesis
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- King Saud University