Clinical trials: INTERACT Condition
Communication Disabilities
Improving Communication and Healthcare Outcomes for Patients With Communication Disabilities
In the United States, 14% of all adults report a speech, language, voice, and/or hearing disability (collectively known as communication disabilities, CD).
- Trial name
- NCT04697212
- Testing
- Healthcare team- + patient-directed intervention, Healthcare team-directed intervention
- Where
- 5 sites in United States
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cerebral Palsy, Spastic
Effect of Task-Specific Training in an Augmented Reality Context on Upper Limb Function and Activities in Children With Spastic Cerebral Palsy
Children with Cerebral Palsy (CP), a condition that affects movement and coordination, face difficulties in daily activities such as dressing, reaching for objects in high places, and getting up from seats.
- Trial name
- INTERACT (NCT06571929)
- Testing
- INTERACT
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Myocardial Infarction, Cerebrovascular Accident
Analyzing Gene Regions That May Interact With the Effectiveness of High Blood Pressure Drugs
High blood pressure is one of the most common health problems in the United States. There are many drug treatment options for high blood pressure, but these medications are not always effective.
- Conditions
- Myocardial Infarction, Cerebrovascular Accident, Death, Sudden, Cardiac
- Trial name
- NCT00573092
- Where
- United States
- Sponsor
- University of Washington
Chronic Kidney Disease
Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)
Sedentary behavior is engaging in activities in the seated or lying position that barely raise the energy expenditure level and has emerged as an important risk factor for obesity, diabetes, cardiovascular disease and mortality.
- Trial name
- SLIMM (NCT02970123)
- Testing
- Sit Less, Interact, Move More (SLIMM)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Srinvasan Beddhu
Depressive Disorder, Major
Probiotics and the Gut Brain Axis- Do Probiotics Interact With the Vagal Nerve?
The purpose of this study is to investigate the effects of a multispecies probiotic on the function of the vagal nerve in patients with major depression and healthy participants in a single-center, randomized, placebo-controlled…
- Trial name
- ProBIO-HRV (NCT04772664)
- Testing
- Multispecies-Probiotic
- Where
- Austria
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Metabolic Syndrome X
Efficacy Study Regarding the Beneficial Effects of Omega-3 Fatty Acids on Cardiometabolic Health
Fish oil supplements (which are rich in omega-3 fatty acids) have been shown to provide cardiometabolic benefits to individuals of all ages.
- Trial name
- FOHS (NCT02042274)
- Testing
- Fish oil supplement
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Guelph
COMBO Condition, STIGMA Condition
Effects of Internet-based Storytelling Programs in Reducing Mental Illness Stigma With Mediation by Interactivity and Stigma Content
Mental illness stigma has been a concerning issue globally due to its adverse effects on the recovery of people with mental illness and may delay help-seeking for mental health out of the concern of being stigmatized.
- Conditions
- COMBO Condition, STIGMA Condition, INTERACT Condition, CONTROL Condition
- Trial name
- NCT05333848
- Testing
- Internet-based storytelling programs with interactivity and stigma content, Internet-based storytelling programs with stigma content only, Internet-based storytelling programs with interactivity only
- Where
- Hong Kong
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mechanically Ventilated Patients, Acute Respiratory Failure (ARF)
Impact of Inspiratory Effort and Patient-Ventilator Interaction During the Transition Phase
The goal of this observational study is to learn whether breathing effort and patient-ventilator asynchrony (PVA) during the transition phase are associated with clinical outcomes in mechanically ventilated adults.The main…
- Trial name
- PV-INTERACT (NCT07896967)
- Testing
- PVA classification software
- Where
- Chile
- Volunteers
- 250 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Violence, Substance Use
Project IntERact Study
This study will use a randomized control trial design (RCT) to pilot test a multisession remote therapy behavioral intervention for risky firearm behaviors and associated behaviors/consequences among adolescents.
- Conditions
- Violence, Substance Use, Criminal Behavior
- Trial name
- NCT03940716
- Testing
- IntERact
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Triple Negative Breast Neoplasms
Psychological Factors and Oncological Outcomes of Triple-negative Breast Cancer
It has been established that chronic stress can take a toll on one's health. Furthermore, when an someone falls ill, it is believed that the way that they handle stress and/or adversity can positively or negatively impact the…
- Trial name
- PSY-ONC TNBC (NCT04669522)
- Volunteers
- 50 people
- Sponsor
- Pius-Hospital Oldenburg
Firearm Violence, Firearm Carriage
Project IntERact V2
The present study is evaluating the efficacy of a behavioral intervention to reduce risky firearm carriage among a high risk sample of youth reporting recent firearm carriage and ownership of a smartphone.
- Conditions
- Firearm Violence, Firearm Carriage, Injury Prevention
- Trial name
- NCT05109325
- Testing
- IntERact
- Where
- 3 sites in United States
- Volunteers
- 373 people
- Sponsor
- University of Michigan
Peritoneal Metastases From Gastric Cancer
INTERACT Stomach-II
This is a phase II study conducted in three hospitals in the Netherlands (Erasmus MC in Rotterdam, Catharina Hospital in Eindhoven, and the Netherlands Cancer Institute in Amsterdam). A total of 55 patients will take part.
- Trial name
- NCT07133490
- Testing
- intraperitoneal chemotherapy
- Where
- 3 sites in Netherlands
- Volunteers
- 55 people
- Sponsor
- Erasmus Medical Center
Child Behavior Problem, Preterm
I-InTERACT Preterm Parenting
Many children born very preterm experience behavior problems, and existing resources for parenting these children are lacking. A pilot trial established the effectiveness of a preterm parenting intervention, I-Interact Preterm…
- Conditions
- Child Behavior Problem, Preterm, Parent-Child Relations, Parenting
- Trial name
- I2P-RCT (NCT06767293)
- Testing
- I-InTERACT Parenting Intervention (I2P) and coaching sessions, I-InTERACT Parenting Microlearning Intervention (I2P Micro) and coaching sessions, Internet Resources
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sleep Disorder Insomnia Chronic
A Study of the Mechanisms by Which Mood and Sleep Disorders Interact
The main purpose of the study is to explore the mechanisms by which mood and sleep disorders interact. The exploratory aim of this study is to discover the relationship between ECG/MCG and EEG/MEG characteristics and mood and…
- Trial name
- mechanisms (NCT07495189)
- Testing
- electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data, ambulatory electrocardiogram, General clinical information
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Traumatic Brain Injury
Internet-based Interacting Together Everyday, Recovery After Childhood TBI (I-InTERACT)--RRTC
The purpose of this study is to test two on-line interventions for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01214694)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI (I-InTERACT), Internet-based-Interacting Together Everyday, Recovery after Childhood TBI Express (I-InTERACT Express), Internet Resources Comparison (IRC)
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Traumatic Brain Injury
Interacting Together Everyday: Recovery After Childhood Traumatic Brain Injury (TBI) "I-InTERACT
The purpose of this study is to test an on-line intervention for families of young children who have experienced moderate or severe traumatic brain injury (TBI).
- Trial name
- I-InTERACT (NCT01056146)
- Testing
- Internet-based Interacting Together Everyday: Recovery After Childhood TBI, Internet Resources Comparison
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study
This phase II trial studies how well letrozole, anastrozole, or fulvestrant work when given together with ribociclib, palbociclib, and/or abemaciclib in treating patients with hormone receptor (HR) positive breast cancer that has…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8
- Trial name
- NCT04256941
- Testing
- Abemaciclib, Anastrozole, Fulvestrant
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
HIV Infections
Study of How Indinavir (an Anti-HIV Drug) and Rifabutin (a Drug Used to Treat MAC, an HIV-Associated Disease) Interact in HIV-Positive and HIV-Negative Adults
The purpose of this study is to evaluate the safety of giving indinavir and rifabutin at the same time (simultaneously) vs 4 hours apart (staggered) to HIV-positive and HIV-negative adults.
- Trial name
- NCT00000877
- Testing
- Indinavir sulfate, Rifabutin
- Where
- 8 sites in United States
- Volunteers
- 31 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pancreatic Cancer, Head and Neck Cancer
Creation of the BioBank, Early Detection and Discovery Biomarkers
To establish a multidisciplinary research structure for tissue repository that facilitates projects that bridge specialties that normally may or may not interact.
- Conditions
- Pancreatic Cancer, Head and Neck Cancer, Breast Cancer
- Trial name
- NCT00901680
- Where
- United States
- Volunteers
- 3,028 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Chronic Kidney Diseases, Obesity
Sit Less, Interact and Move More (SLIMM) 2 Study
Prolonged sitting (sedentary behavior) is a risk factor for decreased kidney function, obesity, diabetes and mortality. Prolonged sitting is associated with decreased kidney function and increased risk of diabetes, heart disease…
- Trial name
- NCT05173714
- Testing
- SLIMM, Standard Resistance Training, Guided Resistance Training
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Srinvasan Beddhu