Clinical trials: IOL
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Premium Monofocal IOL
Multicentric, retro- / prospective, open-label, observational PMCF study to investigate visual performance, contrast sensitivity and patient satisfaction after mono- or bilateral implantation of Isopure 1.2.3.
- Trial name
- PHY2110 (NCT04874376)
- Testing
- IOL implantation experimental (Isopure 1.2.3.)
- Where
- 6 sites in Spain
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)
To evaluate the safety and effectiveness of the ZM900 Tecnis Multifocal lens. Results from two studies (an original study with 125 multifocal and 123 monofocal subjects, protocol DIOL-101-TCNS, and an expansion study with 222…
- Trial name
- NCT00747565
- Testing
- Tecnis ZM900 Multifocal Intraocular Lens, CeeOn 911A monofocal IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Posterior Capsule Opacification
Posterior Capsule Opacification (PCO) With Single Piece Hydrophobic Versus Hydrophillic Intraocular Lens (IOL)
The purpose of the study was to compare the postoperative PCO results of the single-piece hydrophobic Acrylic IOLs versus the newer generation single-piece hydrophilic Acrylic IOLs in patients undergoing bilateral cataract…
- Trial name
- NCT01125345
- Testing
- Phacoemulsification
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract, Lens Opacities
PMCF Study on Comparison of EDOF Lenses (Switzerland)
Single center, prospective, randomised, controlled, double-blind post-market clinical follow-up (PMCF) study to compare the clinical outcomes of a premium monofocal intraocular lens (PhysIOL ISOPURE 1.2.3.) with clinical data…
- Trial name
- PHY2130 (NCT05235139)
- Testing
- IOL implantation experimental (ISOPURE 1.2.3.), IOL implantation active comparator (Acrysof Vivity)
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Comparison of Gemini III Rev 2 Implanted in Conjunction With an Approved IOL vs Eyes Implanted With an Approved IOL
This study is a prospective, observational, randomized, controlled, paired eye, subject-masked design.
- Trial name
- NCT04059796
- Testing
- Omega Gemini III Rev 2 Device, Control Eye
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Cataract
Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens
The study was designed to assess the spectacle independence and satisfaction of patients receiving the AcrySof® Panoptix® Toric intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04128514
- Testing
- Panoptix Toric
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eye Center of North Florida
Cataract
Clinical Investigation of Expanded Designs of a Multifocal IOL
The purpose of this clinical trial is to evaluate the safety and effectiveness of the TECNIS Multifocal 1-Piece Intraocular Lens (IOLs), Models ZKB00 and ZLB00 which will each provide statistically better distance-corrected near…
- Trial name
- NCT01714635
- Testing
- Tecnis Multifocal Intraocular Lens, Monofocal Intraocular Lens
- Where
- 18 sites in United States, United Kingdom
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Presbyopia
Comparison of Two Different Optical Biometric Systems
Primary objective of this study is to evaluate and compare the measurements of two different optical biometrics systems in patients who will undergo cataract surgery or presbyopia surgery using intraocular lenses (IOL-PC).
- Conditions
- Cataract, Presbyopia, Ocular Biometry, Intraocular Lens
- Trial name
- NCT05411341
- Testing
- Argos (Alcon Laboratories, Inc.), IOLMaster 500 (Carl Zeiss Meditec AG)
- Where
- Greece
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Cataract, Refractive Errors
Comparison of Intraocular Lens Power Calculation Methods After Corneal Laser Refractive Surgery in Axial and Refractive Ammertropia
The study aims at determining the best biometry calculation formula to be used in IOL calculation of cataract patients how previously underwent laser refractive correction surgery
- Trial name
- NCT01979172
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The National Eye Hospital, Cairo, Egypt
Complications
Characteristics and Risk Ratios of Late Intraocular Lens (IOL) Complication
Late in-the-bag intraocular lens (IOL) dislocation occurs up to 30 years after cataract surgery and the prevalence ranges from 0.1% to 3.0%.
- Trial name
- NCT02747667
- Volunteers
- 10,125 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Toric Intraocular Lens Stability, Visual Quality
Toric Intraocular Lens (IOL) Implantation for Management of Cataracts
This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.
- Trial name
- NCT05797298
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract
A-constant Optimization of a Toric Monofocal IOL
The study is a prospective series study to determine the IOL constant of a hydrophilic toric monofocal intra-ocular lens (IOL)
- Trial name
- NCT04944238
- Testing
- Ankoris
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Corneal Astigmatism
Toric IOL vs Non-toric IOL With LRI for Corneal Astigmatism
The purpose of the study is to compare the astigmatism reducing effect of a toric intraocular lens (IOL) (model MX60T - Bausch \& Lomb) with that of limbal relaxing incisional surgery combined with a non toric IOL (model MX60 …
- Trial name
- NCT03633851
- Testing
- Toric intraocular MX60T lens, Standard MX60 plus corneal incisions
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ashford and St. Peter's Hospitals NHS Trust
Cataract
The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction
This will be a single arm, open-label, prospective study of patient-reported outcomes of patients with bilateral implantation of the Panoptix or Panoptix Toric implant.
- Trial name
- NCT05346172
- Testing
- PanOptix or PanOptix Toric IOL
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Pseudoaphakia
Time Study for Biometry Measurements With the Lenstar and IntraOcularLens (IOL) Master 500
The objectives of this study are to determine the time needed to complete a full set of measurements (Total Ophthalmic Exam, Subject Data Entry and Acquisition of the Measurement) by each test device, the Lenstar 900 Version i4…
- Trial name
- NCT01550939
- Testing
- Ophthalmic Biometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Haag Streit USA
Refractive Assessment
Visual Performance After RESTOR Implantation
The purpose of this study is to evaluate the distance, intermediate, and near vision after aspheric multifocal diffractive AcrySof® ReSTOR SN6AD1 intraocular lens (IOL) implantation.
- Trial name
- NCT01065064
- Testing
- RESTOR IOL
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Cataract
Rotational Stability of Acrysof IQ Vivity Extended Vision Toric IOL and Refractive Visual Outcome.
The purpose of this research is to assess the rotational stability of the AcrySof IQ Vivity Extended Vision Toric IOL and Refractive Visual outcome.
- Trial name
- NCT05119127
- Testing
- Alcon Vivity toric intra ocular lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kevin Barber
Cataract
Clinical Investigation of Omega Refractive Capsule Model V With Use of an FDA Approved IOL
The objective of this study is to evaluate the safety and effectiveness of the investigational Omega Refractive Capsule (model V)
- Trial name
- ORCV (NCT04574102)
- Testing
- Omega Refractive Capsule with FDA approved Intraocular Lens, FDA approved Intraocular lens
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Lenses, Intraocular Sensitivity
A Pilot Study Investigating the Impact of Different IOL Designs on Subjective 2D and 3D Image Quality
The WHO, states that age related cataracts account for 51 percent of worldwide blindness and affect about 20 million people. Surgery with intraocular lens (IOL) implantation is the first line treatment for cataracts, thus there…
- Conditions
- Lenses, Intraocular Sensitivity, Visual Acuity
- Trial name
- NCT02409641
- Testing
- Cyclopentolatehydrochloride 0,5% eye drops
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Patient Satisfaction
Patient Satisfaction in Post-LASIK Patients With Presbyopia-Correcting IOLs vs. Post-Lasik Patients With Monofocal IOLs
Compare functional visual outcomes and patient satisfaction of post-LASIK patients having received presbyopia-correcting IOLs versus post-LASIK patients having received monofocal IOLs
- Trial name
- NCT04134507
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute