Clinical trials: IOL
AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma
Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. This phase I trial is studying the side effects and best dose of 17-N-allylamino-17-demethoxygeldanamycin in…
- Conditions
- AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma
- Trial name
- NCT00004241
- Testing
- tanespimycin, pharmacological study
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute (NCI)
Cataract
Pseudophakic Eyes With Presbyopia-correcting IOLs: OCT Biometry and Pyramid Aberrometry
To correlate ocular morphology from anterior segment OCT and pyramid wavefront sensing in order to comprehensively analyze pseudophakic in vivo image quality of presbyopia-correcting IOLs in cataract patients.
- Trial name
- NCT07436247
- Testing
- Osiris-T Pyramid Wavefront Sensor - (CSO, Italy)
- Where
- 2 sites in Austria
- Volunteers
- 80 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract and IOL Surgery, VR-based Informed Consent
VR for Cataract Anxiety Lowering Management--A RCT Study
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07620821)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 223 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cataracts
Visual Function Evaluation of Bilateral AcrySof ReSTOR Aspheric IOL
The objective of this study is to evaluate postoperative visual function in patients implanted bilaterally with the ReSTOR Aspheric Intraocular Lens (IOL).
- Trial name
- NCT00818116
- Testing
- AcrySof ReSTOR Aspheric IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Alcon Research
Intraocular Lens, Cataract
Comparison of a Novel Non-diffractive Extended Depth of Focus Intraocular Lens (IOL) and a Trifocal IOL
The purpose of this study is to compare visual performance and quality of life (QOL) following bilateral implantation of a novel non-diffractive extended depth-of-focus (EDOF) intraocular lens (IOL) (AcrySof® IQ Vivity, Alcon…
- Conditions
- Intraocular Lens, Cataract, Quality of Life
- Trial name
- NCT05262504
- Testing
- İntraocular lens implantation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Baskent University Ankara Hospital
Cataract Senile
Achieving Hybrid Monovision By Paring Monofocal And EDOF Lens Technology
Modern day cataract surgery isn't just a rehabilitative procedure anymore but rather aims at improving a patient's quality of life by reducing the need for spectacles in everyday life to a minimum.
- Trial name
- NCT05347615
- Testing
- IOL Implantation:EDOF lens, IOL Implantation: Monofocal lens
- Where
- Austria
- Volunteers
- 29 people
- Sponsor
- Johannes Kepler University of Linz
Cataract, Corneal Astigmatism
Rayner Toric IOL Rotational Stability
This study evaluates the Rayner T-flex Toric IOLs for spherical and astigmatic correction, and rotational stability in cataract surgery.
- Trial name
- Rayner-toric (NCT02393313)
- Testing
- Cataract surgery, Rayner T-flex Toric IOLs
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cataract
Lenstec Softec HD Posterior Chamber Intraocular Lens Clinical Investigational Protocol
The objectives of this multi-center clinical investigation are to determine the safety and effectiveness of the Lenstec Softec HD Posterior Chamber intraocular lens (IOL) following one year of post-operative assessment.
- Trial name
- NCT00963742
- Testing
- Lenstec Softec HD IOL implantation
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract
Cell Ongrowth and Biocompatibility Study of Two Different (Hydrophobic Acrylic) Intraocular Lenses: IOL XY1 vs. IOL XY1A
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- NCT06708806
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataract, Keratoconic Subjects
Visual Outcomes and Quality of Life After Vivity EDOF IOL Implantation in Early-Stage Keratoconus
The goal of this clinical trial is to learn if the Vivity Extended Depth of Focus intraocular lens works to improve vision in adults with cataracts and early-stage keratoconus.
- Trial name
- VIVITY-KCONUS (NCT07338708)
- Testing
- Extended Depth of Focus Intraocular Lens Implantation
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Cataract
Safety and Efficacy of Next Generation Ophthalmic Irrigating Solution Compared to BSS Plus
The purpose of this study is to determine the safety and efficacy of Next Generation Ophthalmic Irrigating Solution (NGOIS) compared to BSS Plus for use during cataract extraction and intra-ocular lens (IOL) implantation.
- Trial name
- NCT00333268
- Testing
- Next Generation Ophthalmic Irrigating Solution (NGOIS), BSS Plus
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Alcon Research
Cataract
Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye
The objective is to assess binocular distance-corrected near (40 cm) visual acuity of patients after uneventful cataract surgery with bilateral implantation of the AcrySof® Vivity Intraocular lens (IOL) when the non-dominant eye…
- Trial name
- NCT04482439
- Testing
- Vivity Extended Depth of Focus intraocular lens (IOL)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Newsom Eye & Laser Center
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of a Trifocal IOL
This study is a prospective, multicenter, randomized, double masked confirmatory trial comparing an investigational trifocal intraocular lens (IOL) and a commercially available monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT04176965
- Testing
- FINEVISION HP IOL, Alcon AcrySof SN60AT
- Where
- 20 sites in United States
- Volunteers
- 539 people
- Sponsor
- Beaver-Visitec International, Inc.
Aphakia, Astigmatism
Clareon IOL Retrospective Data Collection
The purpose of this study is to provide real world evidence (RWE) on the performance of the Clareon ultraviolet absorbing (UVA) intraocular lenses (IOLs) to support the overall body of evidence on the Clareon IOL family.
- Trial name
- NCT05796674
- Testing
- Clareon UVA IOL, WaveTec Optiwave Refractive Analysis (ORA) System, Cataract surgery
- Where
- United States
- Volunteers
- 1,090 people
- Sponsor
- Alcon Research
Partial Edentulism, Tooth Disease
A Study of Osseotite Certain Prevail Implants Used to Support Short Fixed Bridges With Immediate Occlusal Loading.
This prospective, multicenter study evaluates the performance of the Osseotite Prevail implant when to support a short fixed bridge with immediate occlusal loading, providing the patient with the use of a temporary prosthesis…
- Trial name
- Fireball (NCT00728962)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- ZimVie
Presbyopia, Pseudophakia
Synergy Lens Outcomes Evaluation
This is a single visit study to evaluate the visual outcomes and patient satisfaction of patients who were bilaterally implanted with the Tecnis Synergy IOL between June 1 and December 31, 2021 in 2 centers in USA
- Trial name
- NCT05418153
- Testing
- Tecnis Synergy IOL
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Center For Sight
Iol, Astigmatism
Clinical Evaluation of Efficacy and Stability of AT TORBI 709M 4-haptic Toric IOL in Cataract Surgery
The purpose of this study is to evaluate the efficacy and stability of AT TORBI 709M 4-haptic toric IOL in cataract surgery.
- Trial name
- NCT02618018
- Testing
- AT TORBI 709M
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Cataract, Astigmatism
Safety and Effectiveness of the Akreos Toric Intraocular Lens.
The purpose of this study is to evaluate the safety and effectiveness of the Akreos Toric IOL following cataract surgery.
- Trial name
- NCT00825513
- Testing
- Akreos Toric IOL, Akreos Advanced Optics Aspheric Intraocular Lens (Akreos AO)
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Bausch & Lomb Incorporated
Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma
RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors
This phase I clinical trial is studying the side effects and best dose of RO4929097 when given together with capecitabine in treating patients with refractory solid tumors.
- Conditions
- Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma
- Trial name
- NCT01158274
- Testing
- gamma-secretase/Notch signalling pathway inhibitor RO4929097, capecitabine, laboratory biomarker analysis
- Where
- 2 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Posterior Capsule Opacification After Phacoemulsification and IOL Implantation
Long-term Evaluation of Single-piece ACrysof IOL Implantation on Development of Posterior Capsule Opacification
Although contemporary cataract surgery has made tremendous strides in technological advancement, posterior capsular opacification (PCO) is still the most frequent long-term complication leading to decreased visual functions and…
- Trial name
- NCT01820065
- Testing
- Cataract surgery with IOL implantation
- Where
- India
- Volunteers
- 390 people
- Sponsor
- Iladevi Cataract and IOL Research Center