Clinical trials: IOP
Intraocular Pressure, Glaucoma
Comparison of Intraocular Pressure Measurements Between Reichert Tono-Vera Tonometer and Goldmann Tonometry
Determine if the Tono-Vera Tonometer accurately measures intraocular pressure (IOP). The hypothesis of this test is to confirm the Tono-Vera Tonometer is equivalent to the Goldmann Applanation Tonometer (within +/- 5.0 mmHg).
- Trial name
- NCT04360369
- Testing
- IOP with Goldmann Applanation Tonometer, IOP with comparator ORA G3 and ic100 tonometers, IOP with Tono-Vera Tonometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Reichert, Inc.
Glaucoma
Functional and Structural Imaging for Glaucoma
The specific aims of the clinical studies are to: Develop a directional high-resolution OCT and OCT angiography prototype to improve imaging of structure and perfusion.
- Trial name
- FSOCT (NCT01957267)
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Intraocular Pressure
Assessment of a New Goldmann Applanation Tonometer
The classic Goldmann applanation tonometer has been further developed. The applanation principle has been retained, while the internal force transmission and the pressure gauging have been optimized, and the display of results…
- Trial name
- NCT00555763
- Testing
- Tonometry
- Where
- Switzerland
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Healthy Participants
The Effects of Strength Training Volume, Intensity, and Breathing Techniques on Intraocular Pressure and Retinal Blood Vessels
This study aims to determine the effects of different breathing patterns on ocular vasculature and intraocular pressure (IOP) during isokinetic and isometric strength exercises.
- Trial name
- NCT07326462
- Testing
- Normal Breathing, Valsalva maneuver
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Intraocular Pressure, Osteopathic Manipulative Treatment
Effect of Osteopathic Techiniques on Intraocular Pressure
The purpose of this study is to assess the effects osteopathic techniques at the upper cervical vertebrae or at the sphenopalatine ganglia on the intraocular pressure.
- Trial name
- NCT04863209
- Testing
- Upper cervical manipulation, Sphenopalatine ganglion manipulation
- Where
- Brazil
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Intraocular Pressure, Central Corneal Thickness
Reliability of Dynamic Contour Tonometry (DCT)
Study wants to test reliability Dynamic Contour Tonometry (DCT) in measuring intraocular pressure (IOP) and Ocular Pulse Amplitude (OPA).
- Trial name
- DCT (NCT01579331)
- Testing
- DCT (PASCAL© Tonometer) IOP and OPA measurement
- Where
- Italy
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Intraocular Pressure
Effects of Weight Loss From Bariatric Surgery on Intraocular Pressure (IOP)
The purpose of this study is to determine if there is an effect on the eye pressure from extreme weight loss by bariatric procedures.
- Trial name
- IOP (NCT00837226)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Intraocular Pressure
Evaluation of Comfort With Xibrom (Bromfenac Ophthalmic Solution)0.09% and Nevanac (Nepafenac Ophthalmic Suspension) 0.1% Following Selective Laser Trabeculoplasty (SLT)
The objective of this study is to evaluate and compare the comfort of bromfenac or nepafenac following SLT.
- Trial name
- NCT00828477
- Testing
- Xibrom, Nevanac
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Intraocular Pressure and PROSE Lens
Tonometry Precision and Accuracy During PROSE Scleral Lens Wear: A Pilot Study
The goal of this research is to determine the reproducibility of measurements of intraocular pressure (IOP) when a scleral lens is on the eye.
- Trial name
- NCT04308941
- Testing
- Intraocular pressure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Open-Angle Glaucoma, Ocular Hypertension
A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma
Hypothesis: H1: Efficacy of Duotrav will be superior to Xalacom at 24 hours post dosing when both medications are given in the morning H2: A significant proportion of patients will prefer dosing of once daily topical fixed…
- Trial name
- DVX (NCT00887029)
- Testing
- DuoTrav (travoprost-timolol ophthalmic drops), Xalacom (latanoprost-timolol ophthalmic drops)
- Where
- 2 sites in Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants Centres, Canada
Pain
Assessment of Comfort Level Following an Intravitreal Injection by 30 or 32 Gauge Needles
The purpose of this study is to determine if a smaller needle size reduces discomfort suffered by patients both during and following intravitreal injections.
- Trial name
- NCT02142114
- Testing
- Eye injection by 30 or 32 gauge needle
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Retina Health Center
Glaucoma, Open-Angle, Healthy
Sensing Contact Lens-based Device for 24-hour Monitoring of Intraocular Pressure
Glaucoma is characterized by irreversible vision loss through the progressive death of optic nerve fibers unless timely diagnosis and adequate treatment are provided.
- Trial name
- NCT03689088
- Testing
- Goldfish, Tonometry
- Where
- Poland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Pregnancy
Corneal Biomechanics During Pregnancy
It is known that intraocular pressure changes during pregnancy. Collagen structure changes during pregnancy to enable softening of the symphysis, whitening of the birth chanel, and, thus, ultimately to enable delivery of a child.
- Trial name
- CorvisPreg (NCT04433689)
- Testing
- Non-Contact measurement of corneal properties
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Glaucoma
Intraocular Pressure (IOP) Changes Associated With Muslim Prayer Postural Changes
Elevated intraocular pressure is widely accepted as a risk factor for glaucoma and controlling the pressure remains the cornerstone of effective treatment.
- Trial name
- NCT00454025
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Glaucoma, Intraocular Pressure
Intraocular Pressure During Static Apnea
This prospective observational study evaluated changes in intraocular pressure (IOP) during dry static apnea (STA) in breath-hold divers.
- Conditions
- Glaucoma, Intraocular Pressure, Apnea
- Trial name
- NCT07604428
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Olomouc
Retinal Bloodflow
Regulation of Retinal Bloodflow Pressure
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT03398616
- Where
- Austria
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gerhard Garhofer
Post-Injection Intraocular Pressure Spikes
Pre-Administration of Brimonidine in Intravitreal Anti-VEGF Therapy
In this study, investigators will be examining the intraocular pressure lowering effect of brimonidine 0.15% when administered 20min prior to intravitreal anti-VEGF injection.
- Trial name
- NCT03513172
- Testing
- topical brimonidine tartrate 0.15% (Alphagan® P; Allergan, Inc)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Primary Open Angle Glaucoma
Electroretinogram and Retinal Vascular Changes After Cataract Surgery
To compare electrophysiological and Optical coherence tomography angiography of optic disc and macula changes after uneventful phacoemulsification between normal and cataractus patients with primary open angle glaucoma.
- Trial name
- NCT05871034
- Testing
- phacoemulsification
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Myopia
Corneal Biomechanics Study
The goal of the study is to investigate relationship between the corneal response to a temporary increase in intraocular pressure and corneal mechanical properties.
- Trial name
- NCT03658239
- Testing
- Inversion
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Healthy Subjects
SENSIMED Triggerfish® in Sitting and Supine Position
The purpose of the study is to evaluate changes in intraocular pressure (IOP) between sitting and supine body positions and correlate the values obtained with conventional tonometers to the output provided by the investigational…
- Trial name
- NCT01347229
- Testing
- SENSIMED Triggerfish®
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sensimed AG