Clinical trials: ITCH
Cutaneous T-Cell Lymphoma
Recalcitrant Pruritus in Cutaneous T-Cell Lymphoma
The purpose of this study is to define the mechanisms that underlie the refractory pruritus (itch) in Cutaneous T-Cell Lymphoma (CTCL).
- Trial name
- CTCL (NCT00863395)
- Testing
- skin biopsy
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pruritus of the Scalp
In-Use Test of a Cosmetic Product in Subjects With Chronically Itchy Scalp
The aim of the study is to evaluate the tolerance of the Shampoo (WO 5101) on the scalp by a dermatologist and by the subjects themselves after four weeks of regular product use.
- Trial name
- NCT03630107
- Where
- Germany
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dr. August Wolff GmbH & Co. KG Arzneimittel
Uremic Pruritus
The Efficacy of Hemp-containing Cream Versus Placebo in the Treatment of Uremic Pruritus
Uremic pruritus is a significant burden on hemodialysis patients, affecting approximately 46% of individuals undergoing dialysis.
- Trial name
- NCT06159686
- Testing
- Hemp
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Thammasat University Hospital
Tinea Cruris, Jock Itch
Multicenter Study of the Safety and Efficacy of NAFT-500 in Tinea Cruris
A research study to compare the safety and effectiveness of an investigational medication called NAFT-500 to placebo (no active treatment), when used in subjects with tinea cruris, also known as jock itch.
- Trial name
- NCT00750152
- Testing
- NAFT-500
- Where
- 20 sites in United States, Puerto Rico
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Healthy Volunteers
The Effect of Low Level Light Therapy on Histamine- and Mucuna Pruriens-induced Pruritus in Healthy Volunteers
This is a prospective, double-blind, randomised, sham-controlled study whose primary aim is to test whether LLLT changes the intensity of itch after histamine application in healthy volunteers compared to sham application.
- Trial name
- NCT05369338
- Testing
- Low Level Light Therapy
- Where
- Austria
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Itch
Effect of Ketamine, Amitriptyline and Their Combination on Itch
Chronic itch affects approximately a fifth of the global population and is associated with substantial negative consequences for the affected individuals.
- Trial name
- NCT06245564
- Testing
- Ketamine 0.5%, Amitriptyline, ketamine + amitriptyline
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Athletes Foot
Curcuma Extract Beneficial for Muscle Damage
Muscle damage and inflammation is a clinical problem caused by the unimpeachable body adaptation of strenuous exercise through increasing free radicals.
- Trial name
- NCT04439981
- Testing
- Ice cream
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitas Muhammadiyah Semarang
Atopic Dermatitis
The Effect of Visual Stimuli on Itch Perception Intensity in Healthy and Atopic Dermatitis Patients
The purpose of this research study is to assess whether seeing other people itch affects itch perception in patients with atopic dermatitis and healthy subjects.
- Trial name
- NCT00660127
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pruritus, Skin Disorder
Defining N-Acetyl Cysteine as a Treatment for Inhibiting Prurogenic Stimuli
The objective of this double-blinded placebo-controlled cross-over study is to define the role of the over the counter agent, N-acetyl cysteine (NAC), in mitigating the development of pruritus (skin itching).
- Trial name
- NCT05287724
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wright State University
Diet Habit, Body Weight
Sports Nutrition Assessment Program
The NutriEvalUA program is an observational study aiming to assess the nutritional status, body composition, hydration, physical activity, and health indicators in university athletes.
- Conditions
- Diet Habit, Body Weight, Athlete Foot
- Trial name
- NutriEvalUA (NCT07104669)
- Testing
- diet, Physical activity, body composition
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Seasonal Allergic Rhinitis
A Randomized, Double-blind, Placebo-controlled Study on the Effect of CVT-E002 in Patients With Seasonal Allergic Rhinitis
You are being asked to take part in a research study of COLD-fX, a product designed to boost the immune system. COLD-fX is an extract from the roots of North American ginseng and it may offer some benefit to people with seasonal…
- Trial name
- NCT00726401
- Testing
- COLD-fX
- Where
- 4 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Afexa Life Sciences Inc
Pain
Off-set Analgesia Induced by Cold Temperature
In this study, it will be investigated if the phenomenon of offset analgesia, usually associated with painful heat stimulation, could also be induced using cold painful temperatures.
- Trial name
- NCT07395869
- Testing
- Heat off-set analgesia, Cold off-set analgesia
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Itch
Characterization of the Toll-like Receptor 7-agonist Imiquimod 3.75% As a New Surrogate Model of Itch
The aim of this research project is to design a new model of human itch by application of Zyclara cream. Further, the aim is to characterize the model and to verify if the mechanism of action of imiquimod follows the…
- Trial name
- NCT03943407
- Testing
- Zyclara 3.75 % Topical Cream, Prudoxin, Histamine
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aalborg University
Intrahepatic Cholestasis of Pregnancy, Genetic Mutation
Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian Population
Intrahepatic cholestasis of pregnancy (ICP) is a disorder characterized by itching, elevated fasting serum bile acids ≥10μmol/L (and elevated serum transaminases), with increased risks of perinatal complications, including…
- Conditions
- Intrahepatic Cholestasis of Pregnancy, Genetic Mutation, Health Related Quality of Life
- Trial name
- ICP (NCT05691036)
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
End-Stage Kidney Disease (ESKD), Hemodialysis
Cardiovascular and Bone Mineral Markers in Dialysis Patients and Healthy Controls
This observational study will compare cardiovascular status, bone mineral metabolism, systemic inflammation, body composition, functional status, quality of life, pruritus, and pain among patients receiving different renal…
- Conditions
- End-Stage Kidney Disease (ESKD), Hemodialysis, Peritoneal Dialysis (PD)
- Trial name
- NCT07686978
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gazi University
Itch
Testing Protocol to Efficiently Induce Itch
This subproject aims to evaluate a new nerve excitability protocol to induce itch in healthy controls by electrical stimulation.
- Trial name
- ELIT (NCT05195177)
- Testing
- Anti-histamine cream 1 hour, Local anesthetic cream 1 hour
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Intrahepatic Cholestasis of Pregnancy
Unraveling the Pathogenesis of Pruritus in Intrahepatic Cholestasis of Pregnancy
This study hopes identify the main pruritogens of ICP pruritus and provide new insights for the diagnosis, prediction, and treatment of ICP.
- Trial name
- NCT06366659
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking University
Dermatitis, Atopic
Investigation of Topical SB705498 on Healthy Volunteers
A two part, randomized, double-blind, placebo controlled study to investigate the effects of topical doses of SB705498 in healthy volunteers.
- Trial name
- NCT01673529
- Testing
- SB705498
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dermatitis, Atopic, Pruritus
The Efficacy of 3% Kanuka Oil Versus 1% Hydrocortisone Cream in Patients With Atopic Dermatitis
Atopic dermatitis is a common disease affecting millions worldwide. A common associated symptom in this population is pruritus. We seek to investigate the use of an natural, over-the-counter cosmeceutical to help this population
- Trial name
- NCT06488742
- Testing
- 3% kanuka oil
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nexgen Dermatologics, Inc.
Athlete Foot
Neurodynamics to Improve Jump Functionality in Trampoline Jump Gymnasts
The goal of neurodynamics is to restore homeostasis of peripheral nerves. In the current context there is varied evidence that links neurodynamics with clinical pain treatments or different pathologies, but little evidence…
- Trial name
- NCT04289857
- Testing
- Neurodynamic training
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia