Clinical trials: IUD
Prenatal Care
Group Antenatal Care: The Power of Peers for Increasing Skilled Birth Attendance in Achham, Nepal
In rural Nepal, the major drivers of underutilization of skilled birth attendance are poverty, poor social support and inadequate birth planning.
- Trial name
- NCT02330887
- Testing
- Group Antenatal Care, Individual Antenatal Care
- Where
- Nepal
- Volunteers
- 2,184 people, healthy volunteers welcome
- Sponsor
- Possible
Contraception, Pain, Acute
Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC2 (NCT06974019)
- Testing
- Buffered Lidocaine, Lidocaine 1% Injectable Solution
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Human Microbiome, Metagenome
Changes in Vaginal, Cervical and Uterine Microflora With Levonorgestrel Intrauterine Device Placement
The goal of this study is to examine changes in the bacterial ecology and inflammatory markers of the female genital tract with levonorgestrel intrauterine device placement.
- Conditions
- Human Microbiome, Metagenome, Contraception, Cytokine
- Trial name
- NCT01496898
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Utah
Attitudes
Pilot #2 of Social Network Intrauterine Contraceptive (IUC) Intervention
This study has two goals: 1) to test an approach to helping women who use intrauterine contraception (IUC) spread the word about this type of long-lasting, highly effective birth control method among their friends and family and…
- Trial name
- NCT02242890
- Testing
- Contraception Information Packet
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
Immediate Post-placental Insertion of the Copper T 380A After Cesarean Delivery Versus 6 Week Post-cesarean Insertion
The purpose of this study is to determine, in a pilot setting, if this study is feasible in terms of recruitment, willingness to be randomized, provision of contraceptive methods, and follow-up.
- Trial name
- NCT01293760
- Testing
- Immediate insertion, 6 weeks interval insertion
- Where
- Uganda
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Genital Tract Mucosal Immunity, Genital Tract Microflora
Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception
This pilot study is being performed to investigate the influence that starting contraception with an IUD has on the local immune cell populations and features, with a particular focus on the cells and cell-surface features that…
- Trial name
- CHIC (NCT01240811)
- Testing
- IUD placement, Levonorgestrel IUD, Copper T380A IUD
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sharon Achilles
Contraception, Postpartum Period
A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period
The primary objective of the investigators study is to determine if there is a difference in continuation rates at six months in women who are randomized to have the Levonorgestrel Intrauterine System (LNG-IUS) inserted at two…
- Trial name
- NCT01161095
- Testing
- LNG-IUS
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Contraception
Immediate Postpartum Insertion of Contraceptive Intrauterine Devices
In this randomized trial, investigators intend to determine the expulsion and discontinuation rate of immediate postpartum intrauterine devices in the patient population of the University of Oklahoma Women's Healthcare…
- Trial name
- NCT03657602
- Testing
- Kyleena Intrauterine System, Mirena Intrauterine System
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pregnancy Complications, Pregnancy Outcome
BioThrax® (Anthrax) Vaccine in Pregnancy Registry
The purpose of this study is to determine if inadvertent receipt of the BioThrax vaccine during pregnancy is independently associated with adverse maternal, pregnancy, or infant health outcomes.
- Conditions
- Pregnancy Complications, Pregnancy Outcome, Congenital Abnormalities
- Trial name
- NCT01653392
- Testing
- Observational Intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Contraception
Early Postpartum Intrauterine Device (IUD) Placement
Women who have just given birth are at high risk for rapid repeat pregnancy, which can lead to negative consequences during the subsequent pregnancy.
- Trial name
- NCT01594476
- Testing
- Levonorgestrel IUS
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain, Acute, Anesthesia, Local
Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion
The primary aim of our study is to evaluate the effect of intracervical anesthesia on pain scores immediately following levonorgestrel-releasing intrauterine system (LNG-IUS) insertion in nulligravida women.
- Conditions
- Pain, Acute, Anesthesia, Local, IUD Insertion Complication
- Trial name
- NCT03111342
- Testing
- Anesthesia, Dry-needling
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Fetal Death
Mifepristone-misoprostol vs. Misoprostol Alone for Second Trimester Fetal Death
The primary aim of this trial is to compare the efficacy of mifepristone-misoprostol versus misoprostol alone for treatment of intrauterine fetal demise between 14 and 28 weeks LMP.
- Trial name
- NCT02633761
- Testing
- Mifepristone, Misoprostol 200mcg
- Where
- 3 sites in Mexico, Vietnam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Stillbirth, Perinatal Death
A Feasibility Randomised Control Trial to Evaluate Early Perinatal Bereavement Counselling for Parents Who Have Experienced a Perinatal Death
The goal of this feasibility randomised control trial is to determine if a trial to evaluate perinatal bereavement counselling for parents who have experienced a perinatal death is feasible.
- Conditions
- Stillbirth, Perinatal Death, Psychological, Grief
- Trial name
- PEARL-C (NCT07494760)
- Testing
- Bereavement Counselling, Usual bereavement care
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Reproductive Health, Pain
The Effect of Music on Pain, Anxiety and Satisfaction During Intrauterine Device Application
This study was planned to determine the effect of music listened to during intrauterine device application on pain,anxiety and satisfaction.
- Conditions
- Reproductive Health, Pain, Women Health
- Trial name
- NCT06215183
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sümeyye Köse
Contraception
Comparison of the Levonorgestrel IUD and the Copper IUD Placed in the Immediate Postplacental Period: A Prospective Cohort Study
The intrauterine device (IUD) is a safe, highly effective, long acting, and reversible form of contraception. The postpartum period is an important moment for contraceptive intervention; however there are many barriers to women…
- Trial name
- NCT02067663
- Testing
- Paragard, Mirena
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Fetal Growth Retardation, Stillbirth and Fetal Death
Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
Fetal growth restriction (FGR) is a significant health care issue, affecting 20,000 Australian pregnancies every year. Undetected FGR is one of the key risk factors for stillbirth, but FGR can also cause significant impairments…
- Conditions
- Fetal Growth Retardation, Stillbirth and Fetal Death, Pregnancy Preterm
- Trial name
- PROTECTMe (NCT05651347)
- Testing
- Melatonin 10 MG
- Where
- 12 sites in Australia, New Zealand
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Monash University
Contraceptive Usage, Bleeding Due to Intrauterine Contraceptive Device
Acceptability and Continuation Rate of Implanon in a Brazilian Public Sector
The main side-effect of Implanon is the changes induces in bleeding patterns including amenorrhea, infrequent to irregular bleeding and frequent and prolonged bleeding; without any previous symptom and it was characterized as…
- Trial name
- NCT01392157
- Testing
- copper-releasing intrauterine device, ENG-releasing implant, LNG-releasing intrauterine system
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Vaginal Bleeding
Does Skyla Insertion Timing Impact Bleeding?
Women presenting for contraception will be offered the IUS Skyla and study participation. Daily bleeding will be collected for a total of 90 days and correlated with insertion timing and baseline endometrial thickness.
- Trial name
- NCT03074903
- Testing
- Intrauterine system
- Where
- 3 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Healthy
IUD Uterine Vascularization and Side Effects
The aim of this study was to evaluate the effect of the LNG-IUS and TCU 380A users on the sub-endometrial vascularization and the uterine artery blood flow using power Doppler analysis and ultrasonography pulsed color Doppler…
- Trial name
- NCT00489463
- Testing
- intra-uterine device (TCu 380A)
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pain, Anxiety
Effect of Virtual Reality Glasses on Pain and Anxiety During Intrauterine Device Insertion in Women
This study aims to evaluate the effect of virtual reality glasses on pain perception and anxiety levels during intrauterine device insertion in women.
- Trial name
- NCT07325695
- Testing
- Virtual Reality Headset
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Serap Ozturk Altinayak