Clinical trials: IV Access
IV Access
Ultrasound-guided Peripheral IJ Study
Difficult venous access in some patients such as those with obesity, IV drug use, chronic illness, or vascular pathology often causes increased discomfort and delayed patient care due to multiple attempts to gain venous access.
- Trial name
- NCT03231345
- Testing
- US guided IJ, Ultrasound
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University Medical Center of Southern Nevada
IV Catheter-Related Infection or Complication, Vascular Access Complication
Blood Sampling Functionality of Extended Dwell Catheters
The purpose of this study is to compare upper arm versus forearm Extended Dwell Catheter (EDC) placement for blood sampling functionality.
- Conditions
- IV Catheter-Related Infection or Complication, Vascular Access Complication, Peripheral Venous Access
- Trial name
- NCT04409418
- Testing
- Extended dwell catheters
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Corewell Health East
Vascular Access Complication
AccuCath Guidewire Intravenous (IV) Device Versus Conventional IV Catheter In General Nursing Use
The study will test a hypothesis that the AccuCath™ System will have a higher rate of successful first attempt peripheral intravenous (IV) placement, higher completion of therapy, fewer complications, longer dwell times, and…
- Trial name
- NCT01943474
- Testing
- AccuCath IV Catheter Device, Conventional IV Catheter Device
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- C. R. Bard
Total Parenteral Nutrition-induced Cholestasis
Expanded Access of Omegaven IV Fat Emulsion to Infants and Children With PNALD
This is an expanded access protocol for use of intravenous fish oil infusion, Omegaven, in infants and children with parenteral nutrition associated liver disease (PNALD) to decrease elevated liver enzymes and direct bilirubin.
- Trial name
- NCT02929303
- Testing
- Omegaven IV lipid emulsion
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Neuroblastoma, Childhood Metastatic Pheochromocytoma
131-I-MIBG Therapy for Refractory Neuroblastoma, Expanded Access Protocol
Metaiodobenzylguanidine (MIBG) is a substance that is taken up by neuroblastoma cells. MIBG is combined with radioactive iodine (131 I) in the laboratory to form a radioactive compound 131 I-MIBG.
- Trial name
- NCT01163383
- Testing
- 131 I-Metaiodobenzylguanidine (131 I-MIBG), 131 I-MIBG
- Where
- United States
- Sponsor
- John Maris
Intravenous Access According to Instructions For Use
Study Comparing the Handling of Two Peripheral IV Catheter Systems
A peripheral intravenous catheter is the most commonly used vascular access device in medicine. Primary objective is to compare insertion and handling of two peripheral intravenous catheters in clinical routine.
- Trial name
- NCT02213965
- Testing
- Peripheral IV catheter
- Where
- 2 sites in Germany
- Volunteers
- 2,340 people
- Sponsor
- B. Braun Melsungen AG
Pre-Approval Access for Administration of Daratumumab Subcutaneously (SC) in Participants Who Are Unable to Receive Intravenous (IV) Daratumumab
The purpose of this pre-approval access (PAA) program is to provide treatment to participants with serious/life-threatening diseases or conditions.
- Trial name
- NCT04264884
- Testing
- Daratumumab
- Sponsor
- Janssen Research & Development, LLC
Vascular Access Complications
Comparison of AccuCath IV Catheter and Conventional IV Catheter in Interventional Radiology
The study will test a hypothesis that the AccuCath™ System will have a higher rate of successful first attempt peripheral IV placement and higher clinician and patient satisfaction compared to Conventional IV Catheters.
- Trial name
- NCT01940354
- Testing
- AccuCath IV Catheter System, Conventional IV Catheter System
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- C. R. Bard
Acute Pain, Procedural Anxiety
Little NIRVANA for Pediatric Pain and Anxiety
The aim of this study is to test the feasibility of using Little NIRVANA (augmented reality (AR)) for managing anxiety and pain for children 2-8 years old during hospital emergency peripheral intravenous (PIV) insertions.
- Conditions
- Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine
- Trial name
- NCT06795126
- Testing
- Little NIRVANA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital
Colorectal Cancer
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess the adverse events and change in disease activity of telisotuzumab adizutecan plus bevacizumab compared…
- Trial name
- AndroMETa-CRC (NCT07525206)
- Testing
- Telisotuzumab adizutecan, Bevacizumab, Trifluridine/Tipiracil
- Where
- 88 sites in United States, Belgium and 8 more
- Volunteers
- 990 people
- Sponsor
- AbbVie
Steroid Resistant Acute Graft Versus Host Disease
Early Access Program With Inolimomab in Steroid-refractory Acute Graft Versus Host Disease
Leukotac (inolimomab) is not approved yet for marketing in any region. In the absence of medical options and based on the safety and efficacy data obtained during the clinical development program (in a phase III (INO-107) and in…
- Trial name
- NCT05047328
- Testing
- inolimomab
- Where
- France
- Sponsor
- ElsaLys Biotech
Difficult Intravenous Access in Pediatrics
Ultrasound Guided IV Access in a Pediatric Emergency Department
The primary objective is to determine whether the use of ultrasound guidance compared to standard IV access improves the proportion of successful IV placement on a first attempt for children in a pediatric emergency department…
- Trial name
- USgIV (NCT02125552)
- Testing
- Ultrasound guidance, Traditional intravenous access
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Children's Hospital of Philadelphia
Expanded Access Use of Tucatinib for HER2+ Metastatic Breast Cancer
Physicians interested in requesting a single patient IND should contact Seattle Genetics' Medical Information (medinfo@seagen.com).
- Trial name
- NCT03424473
- Testing
- Tucatinib
- Sponsor
- Seagen Inc.
Cervical Cancer, Endometrial Cancer
Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Neurotoxicity
- Trial name
- NCT00003624
- Testing
- amifostine trihydrate, cisplatin, paclitaxel
- Where
- 8 sites in United States
- Sponsor
- Gynecologic Oncology Group
Neoplasm Metastasis
A Patient Navigation Program to Increase Access to Early Supportive Care in Patients With Stage IV Solid Tumors
In this randomized clinical trial, patients with Stage IV solid tumors will be enrolled in a patient navigator-led generalist palliative and supportive care intervention or in usual care led by their treating physician.
- Trial name
- NCT03293849
- Testing
- Patient Navigation
- Where
- Mexico
- Volunteers
- 134 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Patient Satisfaction, Patient Preference
Patient Perspective Midline Catheter in the Emergency Department
This study examines the patient satisfaction and perspective on the use of ultrasound guided midline intravenous catheters compared to standard ultrasound guided peripheral catheters.
- Trial name
- NCT05607238
- Testing
- Ultrasound Guided Vascular Access - Midline catheter, Ultrasound Guided Vascular Access - peripheral IV
- Sponsor
- Wake Forest University Health Sciences
Peripheral Venous Catheterization
Short-Axis Versus Long-Axis Ultrasound-Guided Peripheral IV Cannulation in Adults
This randomized study compared two ultrasound-guided techniques for placing a peripheral intravenous cannula in adults aged 20 to 60 years who required intravenous access.
- Trial name
- NCT07683611
- Testing
- Short-Axis Out-of-Plane Ultrasound-Guided Cannulation, Long-Axis In-Plane Ultrasound-Guided Cannulation
- Where
- Pakistan
- Volunteers
- 222 people
- Sponsor
- Lady Reading Hospital, Pakistan
Catheterization, Peripheral, Venous Dilatation
The Effect of Tapping in the Venous Dilatation for Peripheral IV Access
Peripheral intravenous cannulation (PIVC) is one of the most common interventions in medical practice. Venous dilatation is helpful for successful PIV placement.
- Trial name
- Tapping (NCT05265481)
- Testing
- Tourniquet, Manual Tapping, Device tapping
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Florida
Vascular Access Complication
Ultrasound vs Veinviewer in Patients With Difficulty IV Access
Patients with difficulty intravenous access frequently have delay of care in emergency departments because Emergency Department (ED) personnel could not establish intravenous (IV) access for diagnostic blood test or treatment.
- Trial name
- NCT02618252
- Testing
- Zonare, Veinviewer
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Vascular Access Devices
Peripheral Intravenous Catheter Securement With Tissue Adhesive
This clinical trial will compare survival of peripheral intravenous (IV) catheters for patients with a standard IV site dressing alone to patients with standard IV dressing plus Adhezion Biomedical SecurePortIV Catheter…
- Trial name
- NCT04086693
- Testing
- Standard IV dressing, Standard IV dressing plus a tissue adhesive peripheral IV securement device
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Corewell Health East