Clinical trials: IVF
Infertility
Freeze All on Oocyte Maturatin by Gonadotropin Agonist Versus Human Chorionic Gonadotroipin
Estradiol valerate in the form of cycloprogenova™ (white tablet only) was started on day 2 or 3 of cycle with oral dose 4 mg divided on 2 doses in addition to Aspocid 75 mg once daily with folic acid 500 mcg once daily.
- Trial name
- NCT04749979
- Testing
- Agonist (decapeptyl ), HCG ( eg. Choriomon )
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Infertility, Miscarriage, Recurrent
ANXA5 M2 Haplotyping in IVF Patients and Embryos
This study aims to characterize the association between history of pregnancy complications and M2 carrier status in IVF patients and the utility of M2 haplotype preimplantation genetic testing (PGT) in embryos produced by carrier…
- Conditions
- Infertility, Miscarriage, Recurrent, Pregnancy Complications
- Trial name
- NCT04544462
- Testing
- M2 Test
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Embryo Implantation, Infertility
Clinical Trial of Novel Implantation Promoting Medium (EmbryoGlue) to Improve IVF Success Rates
Hypothesis: a special solution for improving human embryo implantation, when added to the solution during embryo transfer, will improve implantation rates in embryo transfers using previously frozen embryos.
- Trial name
- NCT00588250
- Testing
- EmbryoGlue
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Infertility
Endometrial Local Injury and Implantation Failure
The purpose of this study is to evaluate the influence of endometrial biopsy on increasing implantation rate in patients with recurrent implantation failures, 93 women with at least two implantation failures were evaluated.
- Trial name
- NCT00837733
- Testing
- Endometrial biopsy
- Where
- Iran
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility, IVF
Quality of Human Embryos in IVF, Culturing in Differentiated Oxygen
The goal of this clinical trial is to evaluate the importance of differential O2 tension to the developing embryos. As a secondary aim, we investigate the levels of reactive oxygen species (ROS) in spent media from the developing…
- Conditions
- Infertility, IVF, Embryo
- Trial name
- NCT05737381
- Testing
- Differential oxygen tension
- Where
- Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Anxiety, Depression
Coping Intervention After Embryo Transfer
Background of the study: Undergoing an IVF or ICSI treatment is an emotional and physical burden for both the woman and her partner.
- Trial name
- NCT01701011
- Testing
- Coping intervention
- Where
- Netherlands
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Bart CJM Fauser
Infertility, Recurrent Implantation Failure
Endometrial Biopsy Protocol for In Vitro Fertilization (IVF)
Endometrial biopsy has been shown to improve IVF pregnancy and live birth rates. The optimal time of performing the biopsy is yet to be established.
- Trial name
- NCT01278706
- Testing
- endometrial biopsy/ies
- Where
- 2 sites in Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Infertility
Follicular Flushing Versus Direct Aspiration
The purpose of this study is to investigate the impact of follicular flushing on the oocyte recovery rate, oocyte maturity, fertilization rate, and embryo development and utilization as compared to direct aspiration (no flushing)…
- Trial name
- NCT03354858
- Testing
- Follicular flushing
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eugonia
Ovarian Stimulation
Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist
Objective: To compare the efficacy of using mild ovarian stimulation protocol and conventional stimulation protocol in IVF outcome. Design: Prospective randomized trial Setting: University IVF setting.
- Trial name
- NCT00830492
- Testing
- clomiphene citrate, Ultrasound, GnRH antagonist
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility
AMH and Dosing Regimens for Initial IVF Stimulation Protocols
This is a research study on a hormone in women called anti-mullerian hormone (AMH) an indicator of the amount of egg reserve in the ovaries. The research involves a blood draw to determine the AMH level.
- Trial name
- NCT03098199
- Testing
- 300IU Gonal-F, 150IU Menopur, 225IU Gonal-F
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Reproductive Specialists of New York
Pregnancy
The Effect of Acupuncture on Pregnancy Rates in Women Undergoing Embryo Transfer
The present study is designed to test the hypothesis that acupuncture, before and after embryo transfer, significantly improves pregnancy rates, compared to embryo transfer with sham acupuncture and no acupuncture at all.
- Trial name
- AcuIVF (NCT00722462)
- Testing
- Active acupuncture
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Pain
A Randomized Controlled Trial of Oral Acetaminophen for Analgesic Control After Transvaginal Oocyte Retrieval
Current standard of care is no pretreatment medications before the egg retrieval, and the investigators would like to evaluate if preoperative Tylenol improves procedure and post procedure pain control over the current practice…
- Trial name
- NCT02418182
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
In Vitro Fertilization, Assisted Reproductive Techniques
Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.
The aims of this study are to evaluate: 1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF. 2.
- Trial name
- NCT02222831
- Testing
- Day 0 denudation and time lapse culture on IVF-oocytes.
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Recurrent Implantation Failure in Setting of Artifically Prepared Endometrium
Trial of Endometrial Scratch Prior to Frozen Embryo Transfer in Patients With Recurrent Implantation Failure
Patients with a history of recurrent implantation failure who are planning a frozen embryo transfer (FET) are enrolled into the program.
- Trial name
- NCT03157765
- Testing
- endometrial biopsy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brown Fertility
Infertility
Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women
The purpose of this study is to examine the effects of marked alterations in ovarian steroid hormones on cognitive functions in women.
- Trial name
- NCT00113867
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Assisted Reproductive Techniques
Double Stimulation in Women With Low Prognosis in ART
The main objective of this study is to compare the cumulative ongoing pregnancy rates of two different IVF protocols in women candidate for ART characterized by low prognosis.
- Trial name
- NCT04531644
- Testing
- double stimulation, conventional ovarian stimulation
- Where
- Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Poor Ovarian Response
SIRT3 Expression in Granulosa Cells and the Levels of Follicular Fluid Metabolites Among POR Subgroups
The goal of this prospective, observational study is to learn about the pathogenesis and biological target of the subtypes of poor ovarian response (POR) during In vitro fertilization and embryo transfer (IVF-ET).
- Trial name
- POR SIRT3 (NCT06617988)
- Testing
- Not applicable- observational study
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shandong University of Traditional Chinese Medicine
Infertility
Maternal Serum Cytokine Levels and Angiogenic Factor Levels in IVF vs Spontaneously Conceived Pregnancies
The objective of the study is to compare maternal levels of cytokines and angiogenic factors in IVF vs spontaneously conceived singleton pregnancies. The null hypothesis is that there will be no significant difference.
- Trial name
- NCT00837278
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MemorialCare
IVF, Body Weight
Nutritional Status of Women Undergoing in Vitro Fertilization
Infertility affects around 15 % of couples in their reproductive years. Even though the use of assisted reproductive technologies (ART) in aforementioned couples is increasing, their success rate is still relatively low.
- Conditions
- IVF, Body Weight, Nutrient Deficiency, Dietary Vitamin B12 Deficiency Anemia
- Trial name
- NCT05865015
- Where
- 2 sites in Slovenia
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Female Infertility
Effectiveness of Low Dose Gonadotropin Stimulation Protocol Vs High Dose Gonadotropin Protocol in Poor Responders
In the present study we examined the effect of addition of CC to a low dose gonadotropin (150 IU/day) / GnRH antagonist protocol in comparison to a high gonadotropin dose (300 IU/day) regiment (short protocol) in women with poor…
- Trial name
- NCT06778733
- Testing
- Clomiphane citrate, recombinant human Follicle-Stimulating Hormone (r-FSH-alfa)
- Where
- 2 sites in Greece
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Athens