Clinical trials: IVF Outcome
in Vitro Fertilization
The Role of DNA Damage of Granulosa Cell on Oocyte Quality and in Vitro Fertilization Outcome
Deoxyribonucleic acid (DNA) damage of granulosa cells obtained during oocyte retrieval will be evaluated by comet assay in unexplained infertile patients undergoing in vitro fertilization (IVF) treatment.
- Trial name
- NCT03345030
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Vaginal Flora Imbalance
Vaginal Microbiome and IVF Pregnancy Outcome
The aim of this prospective, observational study is to investigate the prevalence of vaginal dysbiosis among women undergoing IVF procedures in the US.
- Trial name
- NCT05150639
- Testing
- IVF
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Infertility
The Impact of Lifestyle Behaviors on In Vitro Fertilization (IVF) Outcome
Many women undergoing in vitro fertilization (IVF) ask their doctor if there are any behaviors they should avoid, or any behaviors they should emphasize during their IVF cycle.
- Trial name
- NCT01119391
- Testing
- There was no intervention; this was a survey only study
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Androgen Profile, Inflammatory Markers
Effect of Resveratrol on Metabolic Parameters and Oocyte Quality in PCOS Patients
Polycystic ovary syndrome (PCOS) is characterized by enlarged ovaries, menstrual irregularity and hyperandrogenism and is the most common cause of oligoovulatory infertility.
- Conditions
- Androgen Profile, Inflammatory Markers, IVF Outcome
- Trial name
- RES-IVF (NCT01782911)
- Testing
- Resveratrol
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Ovarian Function at Advanced Reproductive Age
Co Enzyme Q10 Improves IVF Outcome in With Advanced Reproductive Age
The goal of the investigators research is to explore energy production of the ovarian follicle in older reproductive age women at the time of oocyte retrieval.
- Trial name
- NCT01659788
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Ectopic Pregnancies
Activin A and Inhibin A in Predicting Outcome of Pregnancies of Unknown Location After Assisted Reproductive Technology
The purpose of this study is to determine the predictive value of a single serum determination of activin A and inhibin A for the prognosis of ectopic pregnancy after in Vitro Fertilization (IVF) cycles, in both native and…
- Trial name
- NCT01589016
- Where
- Spain
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Repetition Failure
Clinical Application of Autologous Mitochondria Transplantation for Improving Oocyte Quality.
Embryo quality was ranked as one of the most important predictors in determining the success of implantation, while clinically some patients may experience repeated IVF failure due to persistent poor embryo quality.Mitochondria…
- Trial name
- NCT03639506
- Testing
- autologous mitochondria transplantation, autologous mitochondria from bone marrow mesenchymal stem cells into oocyte as well as intracytoplasmic sperm injection (ICSI), intracytoplasmic sperm injection (ICSI)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Pregnancy
Ghrelin Levels in Early IVF Pregnancies
In this study, we have assessed the potential prognostic value for gestational outcome of maternal ghrelin levels at very early stages of IVF pregnancies.
- Trial name
- NCT00469807
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
In Vitro Fertilization
Bed Rest or no Bed Rest?
A comparative study to determine whether bed rest after embryo transfer (ET) affects on IVF (In Vitro Fertilization)outcome. This study includes 240 patients undergoing IVF treatment with donated oocytes.
- Trial name
- NCT01343992
- Testing
- Bed rest, No bedrest
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Subfertility, Infertility
Hysteroscopy Before in Vitro Fertilization - Does it Improve the Outcome?
By randomizing sub-fertile women to either control or office-hysteroscopy in the circle prior to IVF or ICSI (intracytoplasmatic sperm injection ) treatment, we aim to enlighten whether hysteroscopy with endometrial biopsy…
- Trial name
- NCT01743391
- Testing
- Office-hysteroscopy with biopsy
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Infertility
The Impact of an Online Stress Management Program on In Vitro Fertilization (IVF) Outcome
The goal of this study is to determine the impact of an online stress management program, which combines stress reduction and prevention strategies with personal care products/rituals which have relaxation properties, on…
- Trial name
- NCT01156324
- Testing
- Online Stress Management Group (Upliv), Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston IVF
VITAMIN D Disorders
Serum Vitamin D Level and Its Association With Ovarian Reserve and IVF Outcome
Vitamin D has a major play in bone and calcium metabolism. Vitamin D deficiency (below 20 ng/ml) has also been linked to adverse health outcomes such as malignancy, cardiovascular disease, immune functioning, and glucose…
- Trial name
- NCT02317718
- Testing
- monitor reproductive outcome
- Where
- United Arab Emirates
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fakih IVF Fertility Center
COVID-19, IVF
The Impact of the Previous Exposure to Covid-19 Virus Infection on the Outcome of ICSI Cycles
Whilst the global COVID-19 pandemic is still evolving and there are many unknowns about the long-term effects of the virus on fertility and pregnancy, we found ourselves in need to offer some evidence-based guidance, that's why…
- Trial name
- NCT05198401
- Testing
- covid-19
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Infertility, Female
Melatonin Study Between Diminished and Normal Responder in IVF
Poor sleep quality may lead to increase in oxidative stress and free radicals which in turn may decrease the reproductive function.
- Trial name
- NCT03117725
- Testing
- Melatonin adminstration
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Preterm Birth, Gestational Diabetes Mellitus (GDM)
Evaluation of Maternal and Neonatal Outcomes in Women Are Conceived Through Assisted Reproductive Technology Compared to Other Fertility Treatments and Naturally Conceived Women: It is a Retrospective Cohort Study Conducted Over a 5-year Period at a Fertility Center in a Lebanese Hospital
Background: The number of couples experiencing difficulties conceiving and seeking treatment for infertility has increased dramatically over time.
- Conditions
- Preterm Birth, Gestational Diabetes Mellitus (GDM), Gestational Hypertension
- Trial name
- non (NCT06836843)
- Testing
- Since this is an observational study rather than an interventional study, the exposure type refers to all potential factors influencing pregnancy both before and during pregnancy
- Where
- Lebanon
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Lebanese University
Role of Vitamin D in IVF for Better Outcome
Vitamin D as a Prognostic Marker on Assisted Reproductive Technologies Outcomes.
Studying the effect of Vitamin D administration on assisted reproductive outcomes in women undergoing Intra Cytoplasmic Sperm Injection (ICSI) by giving a dose of vitamin D and determining the effect of this dose on both the…
- Trial name
- NCT05091203
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility
The Impact of Distress on the IVF Outcome
Stress is a primary reason why in vitro fertilization (IVF) patients drop out of treatment, and it may have a detrimental impact on pregnancy rates, yet there is minimal published research on the efficacy of structured…
- Trial name
- NCT01103973
- Testing
- Mind/Body Program, Control
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility, Female, IVF
Effect of Intrauterine Administration of Autologous PBMC Modulated With IFNt on IVF Outcome
The goal of this clinical trial is to test the effect of modulated specialised immune cells isolated from the patients' own blood when administered to the uterus before embryo transfer on the IVF outcome (implantation, pregnancy…
- Trial name
- NCT05775198
- Testing
- PBMC immunomodulated with IFNt
- Where
- Bulgaria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nadezhda Women's Health Hospital
Infertility
The Impact of Lifestyle Behavior on in Vitro Fertilization (IVF) Outcome
The purpose of this study is to prospectively examine the impact of various lifestyle habits in both men and women on the outcome of in vitro fertilization.
- Trial name
- NCT01404858
- Testing
- There is no intervention; this is a survey only study
- Where
- United States
- Volunteers
- 12,800 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Clinical Pregnancy, Embryo Implantation
DNA Amplification in Blastocoel Fluid
Introduction: Although innovative procedural changes in frozen embryo transfer (FET) cycles have increased the implantation rate of blastocysts transferred significantly, blastocyst selection remains a significant limiting factor…
- Trial name
- NCT04744844
- Testing
- blastocoel fluid biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Antalya IVF