Clinical trials: IVF Treatment
Infertility
Long Protocol and Growth Hormone in Poor Responders
The long down regulation protocol is widely used in the in vitro fertilization cycles, now it will be assessed regarding its efficacy, in poor responder females undergoing in vitro fertilization cycles, alone and after the…
- Trial name
- NCT02338206
- Testing
- Growth hormone
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Female Infertility
Recombinant Follicle-stimulating Hormone in Treatment for Infertility
This is a randomized multi-centre, assessor-blind, parallel-group study to be conducted in 250 women in the age group of 20 to 39 years (both inclusive), who are indicated to undergo COS as part of assisted reproductive…
- Trial name
- REFRESH (NCT05266924)
- Testing
- Recombinant Human Follicle Stimulating Hormone 900 IU (66.0 μg) / 1.5mL Solution for Injection in Prefilled Pen
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Bharat Serums and Vaccines Limited
Adenomyosis, IVF
Artificial Cycle With or Without GnRH Agonist Pre-treatment for Frozen Embryo Transfer in Adenomyosis Patients
This randomized clinical trial aims to assess the comparative effectiveness of two distinct endometrial preparation protocols for frozen embryo transfer (FET) among women with adenomyosis undergoing IVF/ICSI.
- Conditions
- Adenomyosis, IVF, Frozen Embryo Transfer
- Trial name
- FET-ADE (NCT06239376)
- Testing
- GnRHa+AI - AC, Artificial cycle
- Where
- Vietnam
- Volunteers
- 222 people
- Sponsor
- Mỹ Đức Hospital
Endometriosis, Infertility Assisted Reproductive Technology
First Line Surgery or First Line Fertility Treatment Using Assisted Reproductive Technologies in Patients With Advanced Endometriosis
Endometriosis is a chronic disease affecting approximately 10% of women of reproductive age. It is strongly associated with pelvic pain and infertility.
- Trial name
- EndoSOFT (NCT07240363)
- Testing
- Endometriosis surgery
- Where
- 4 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Infertility
Evaluation of the Luteolytic Effect of a Gonadotropin Releasing Hormone (GnRH) Agonist After the Administration of Human Chorionic Gonadotropin (hCG) in the Initial Follicular Phase a Its Influence on the Prognosis of in Vitro Fertilization Treatment
This study was designed to evaluate the ability of gonadotropin releasing hormone (GnRh) agonist to prevent the rise of progesterone during controlled ovarian stimulation for in vitro fertilization (IVF) after the administration…
- Trial name
- NCT00948805
- Testing
- GnRH agonist, Control
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Infertility
Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
This is a Phase 3, randomized, controlled, single-blind, multicenter, parallel-arm trial to assess the safety and efficacy of Pergoveris® (recombinant human follicle stimulating hormone [r-hFSH]/recombinant human luteinising…
- Trial name
- ESPART (NCT02047227)
- Testing
- Pergoveris®, GONAL-f®, Recombinant human chorionic gonadotrophin (r-hCG)
- Where
- Germany
- Volunteers
- 939 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Frozen Embryos
Time - Lapse Analysis of Frozen Embryos
A retrospective analysis of embryo defrost cycles that were rated in the EmbryoScope system and frozen will be performed. The study will examine the possible association between the morphokinetic grading received by these embryos…
- Trial name
- NCT04255641
- Testing
- time lapse analysis
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Infertility
Swanson-Based Supportive Care for Infertility Stress and Coping in Couples Undergoing ART
The goal of this clinical trial is to learn if supportive care based on Swanson's Caring Theory can reduce stress and improve coping in couples undergoing infertility treatment with assisted reproductive treatment (ART)…
- Trial name
- NCT07557069
- Testing
- Swanson Caring Theory-based supportive care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ondokuz Mayıs University
Pregnancy Result Rape
The Effect of Luteinizing Hormone (LH) Supplementation Following Gonadotropin-releasing Hormone (GnRH) Antagonist Administration in Advanced Reproductive Ageing Women Undergoing IVF and Embryo Transfer (IVF/ET)
To explore whether recombinant LH (rLH) supplementation (Leuveris) to recombinant follicle stimulating hormone (rFSH) following GnRH antagonist treatment has an advantage in infertile women with advanced reproductive ageing…
- Trial name
- NCT01016210
- Testing
- Leuveris
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Infertility
The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization
This study will be conducted in two phases. In the first phase, research subjects will be assigned to receive standard counseling. In the second phase, research subjects will receive Univfy counseling.
- Trial name
- NCT06319573
- Testing
- Counseling Supported by Univfy® Report, Standard Counseling
- Where
- 2 sites in Spain
- Volunteers
- 366 people
- Sponsor
- Ginefiv
Infertility
IVF Treatment in Women With Immature Oocytes in Previous Cycle
In standard IVF stimulation cycle,human chorionic gonadotropin (hCG) is usually used at the end of controlled ovarian hyperstimulation (COH) as a surrogate to only the luteinizing hormone (LH) surge.
- Trial name
- NCT02368964
- Testing
- GnRH agonist 0.2 mg + hCG 250 mcg, high dose hCG 500 mcg
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Female Infertility Due to Diminished Ovarian Reserve
Microflare Protocol in Poor Responders
The effect of use of the microflare down regulation protocol on the outcome of the IVF/ICSI cycles in poor responders
- Trial name
- NCT02185326
- Testing
- Growth hormone (Norditropin, Novo nordisk)
- Where
- Egypt
- Volunteers
- 145 people
- Sponsor
- Woman's Health University Hospital, Egypt
Anxiety, Stress
Aromatherapy for Mental Health Promotion in IVF Patients
The experience of infertility can cause significant emotional instability, especially for patients awaiting In Vitro Fertilization (IVF) treatment, generating anxiety, stress, and depressive symptoms.
- Conditions
- Anxiety, Stress, Depression Disorder, Quality of Life
- Trial name
- NCT07480668
- Testing
- Lavender essential oil Inhalation, Synthetic lavender aroma inhalation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of Minas Gerais
Infertility, Ovarian Hyperstimulation Syndrome
Short Versus Long Protocol for IVF and IVF+ICSI
Purpose: Comparing a GnRH agonist and an antagonist protocol for IVF/ICSI with regard to 1. frequency of ovarian hyperstimulation syndrome (OHSS) (1. outcome measure) 2. quality of life (2. outcome measure) 3. live birth rate (2.
- Conditions
- Infertility, Ovarian Hyperstimulation Syndrome, Quality of Life, Live Birth
- Trial name
- KvL (NCT00756028)
- Testing
- Patients receiving short protocol IVF/ICSI-treatment., Long protocol
- Where
- 2 sites in Denmark
- Volunteers
- 1,099 people
- Sponsor
- Peter Hornnes, MD, DMSc
Infertility, Female
The Temporo-spatial Dynamics of Genital Tract Microbiota
The investigators aim to examine the endometrium with state of the art sequencing techniques to investigate the endometrial microbiota.
- Trial name
- NCT03363828
- Testing
- Estrofem
- Where
- 2 sites in Denmark
- Volunteers
- 27 people
- Sponsor
- Peter Humaidan
Infertility, In Vitro Maturation of Oocytes
Aspire In Vitro Maturation Study
A study to assess the Capacitation - in-vitro maturation (CAPA-IVM) system as an option for patients with a good ovarian reserve to achieve pregnancy.
- Conditions
- Infertility, In Vitro Maturation of Oocytes, Assisted Reproduction Technologies
- Trial name
- AIM (NCT07789730)
- Testing
- CAPA-IVM
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Inception Fertility Research Institute, LLC
Supervision of Pregnancy Resulting From In-vitro Fertilization
Optimal Planning of a Day 3 Cryopreserved(Frozen)-Thawed Embryo Transfer in a Natural Cycle With hCG Administration or After Spontaneous LH Peak?
The aim of the study is to determine whether spontaneous LH peak is superior to human chorionic gonadotropin before a transfer of a day 3 frozen embryo.
- Trial name
- PLUS (NCT02145819)
- Testing
- hCG, LH peak
- Where
- Belgium
- Volunteers
- 240 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility, Assisted Reproductive Technology Outcomes
The Impact of Having a Tattoo on Fertility Treatment Outcome
Tattoos are increasingly common among women of reproductive age, yet their potential systemic inflammatory effects and impact on fertility treatment outcomes are unknown.
- Trial name
- NCT07405879
- Where
- Canada
- Volunteers
- 328 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Subfertility
Prognostic Value of Progesterone for In Vitro Fertilization (IVF) Outcome
This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF…
- Trial name
- PROG2 (NCT01067664)
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Aristotle University Of Thessaloniki