Clinical trials: IVF Treatment
IVF Outcomes, Prediction Models
Machine-Learning Prediction of Pregnancy Outcomes After Assisted Reproductive Treatments
The goal of this observational study is to develop and validate a machine-learning model to predict pregnancy outcomes in women with a positive pregnancy test following assisted reproductive treatment (ART), with the primary…
- Conditions
- IVF Outcomes, Prediction Models, Infertility Assisted Reproductive Technology, Live Birth
- Trial name
- NCT07855783
- Testing
- Machine-Learning Model for Prediction of Pregnancy Outcomes
- Where
- 2 sites in Croatia
- Volunteers
- 2,200 people
- Sponsor
- BetaPlus Center for Reproductive Medicine
Polycystic Ovary Syndrome
The Influence Factors of Ovarian Response in PCOS Patients With IVF-ET Treatment
The purpose of this study is to explore the factors which affect ovarian response of PCOS patients with IVF-ET treatment, in order to provide predictive clinical index for the outcome of IVF-ET treatment in PCOS patients.
- Trial name
- NCT02331758
- Testing
- Lifestyle Counseling
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Infertility
A Dose-response Trial Using FE 999049 in Japanese Women Undergoing in Vitro Fertilisation (IVF) / Intracytoplasmic Sperm Injection (ICSI) Treatment
This trial investigates the effects of several doses of FE 999049 in Japanese women undergoing IVF/ICSI treatment.
- Trial name
- NCT02309671
- Testing
- FE 999049, follitropin beta
- Where
- Japan
- Volunteers
- 159 people
- Sponsor
- Ferring Pharmaceuticals
Cancer, Cancer in Pregnancy
ProspectiveFemaleAYA - Late Effects of Cancer Therapies on Gonadal Function, Fertility, Efficiency of Fertility Preservation Procedures and Pregnancy Outcomes
In the past two decades, the evidence-based knowledge on the prevalence and risk factors for gonads impairment, including infertility, following cancer and numerous cancer treatment regimen has significantly increased.
- Conditions
- Cancer, Cancer in Pregnancy, Infertility, In Vitro Fertilisation (IVF) Treatment
- Trial name
- FemFertilAYA (NCT07622420)
- Volunteers
- 3,000 people
- Sponsor
- Karolinska Institutet
PCOS, Endometriosis
Pomegranate Juice Effect on Oxidative Stress in Infertile Women During IVF Treatment
tTe investigators estimate pomegranate supplementation effect on oxidative stress in infertile women with PCOS, endometriosis and advanced maternal age during IVF treatment.
- Conditions
- PCOS, Endometriosis, Advised Maternal Age, Male Factor Infertility
- Trial name
- NCT03978013
- Testing
- Pomegranate juice, Apple juice
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Chronic Obstructive Pulmonary Disease, Depression
Investigating the Impact of Mode of Administration on Item Response
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Rheumatoid Arthritis
- Trial name
- NCT00783991
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- Stony Brook University
Minor Intra-uterine Abnormalities
The Impact of Treating Minor Uterine Cavity Abnormalities Diagnosed by Office Hysteroscopy in Unselected In Vitro Fertilization (IVF) Cases
This is a comparative, controlled trial to evaluate the impact of treating undetected, asymptomatic, predefined minor uterine cavity abnormalities on the success of IVF treatment.
- Trial name
- NCT00830401
- Testing
- Treatment of predefined abnormality by hysteroscopic surgery, Ofloxacinum/Doxycycline
- Where
- Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Endometrial Flora Characterization in Infertile Women
Endometrial Flora in Women Undergoing IVF Treatments
Characterization of the female genital tract microbiome in women undergoing IVF treatment
- Trial name
- NCT03208595
- Testing
- Endometrial sampling of a Typical Embryo transfer catheter
- Volunteers
- 150 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Endometriosis, Ovarian Cysts
Danazol Treatment in Endometriosis Women Before IVF
The purpose of this study is to determine whether pre-treatment with danazol for at least 4 months before controlled ovarian hyperstimulation for IVF cycles improves pregnancy rate.
- Conditions
- Endometriosis, Ovarian Cysts, Infertility
- Trial name
- NCT01779232
- Testing
- Danazol
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Infertility, Implantation Failure
Does Local Injury of the Endometrium Improve Controlled Ovarian Hyperstimulation (COH) + Intrauterine Insemination (IUI) Outcome?
It was previously demonstrated in in vitro fertilization (IVF) patients that local injury of the endometrium during a spontaneous menstrual cycle that precedes IVF treatment doubled the rates of implantation and pregnancy.
- Trial name
- NCT01111799
- Testing
- endometrial biopsy, natural cycle + IUI + endometrial biopsy
- Where
- Israel
- Volunteers
- 600 people
- Sponsor
- Meir Medical Center
Luteal Phase, in Vitro Fertilisation
Early Luteal Hormones and IVF Outcomes After hCG Triggering
It has recently been demonstrated that a bolus trigger of hCG induces various unphysiological conditions in the early luteal phase that may negatively affect an IVF treatment cycle's reproductive outcome.
- Trial name
- NCT04693624
- Testing
- Hormonal levels
- Where
- Vietnam
- Volunteers
- 95 people
- Sponsor
- Mỹ Đức Hospital
Infertility, Female
Study to Compare Efficacy and Safety of Primapur and Gonal-f in Women for Assisted Reproductive Treatment
The purpose of this study is to show equivalence with regard to the number of oocytes retrieved between follitropin alfa (pen-injectors) Primapur® and Gonal-f® in woman undergoing IVF/ICSI
- Trial name
- NCT03088137
- Testing
- Follitropin alfa (Gonal-f), Follitropin alfa (Primapur)
- Where
- 3 sites in Russia
- Volunteers
- 118 people
- Sponsor
- IVFarma LLC
Pregnancy, Miscarriage Less Than 12 Gestational Weeks
Low-Dose Aspirin in in Vitro Fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI) Treatments
In this study we hypothesized that low-dose aspirin therapy (100 mg daily) improves ovarian responsiveness, uterine haemodynamics and clinical pregnancy rates in unselected subjects undergoing IVF/ICSI when the treatment is…
- Conditions
- Pregnancy, Miscarriage Less Than 12 Gestational Weeks, Extrauterine Pregnancy, Preeclampsia
- Trial name
- NCT00683202
- Testing
- Acetylsalicylic acid
- Where
- Finland
- Volunteers
- 374 people
- Sponsor
- University of Oulu
Infertility
Efficacy of Endocell® vs Conventional Medium in the Treatment of Infertility
The aim of this study is to demonstrate the efficacy of a single embryo transfer at blastocyst stage (Day 5) after co-culture on Autologous Endometrial Cell Culture (AECC) versus transfer of a single embryo at Day 3 after culture…
- Trial name
- NCT01058603
- Testing
- - Conventional culture medium for IVF, - Endocell®
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Laboratoires Genévrier
In Vitro Fertilization, Ovarian Stimulation
Age Versus Ovarian Reserve Markers Based Therapy in IVF (IVF)/Intracytoplasmic Sperm Injection (ICSI) Cycles
This randomized controlled trial has been designed for carrying out a comparison of new AMH (Anti-Müllerian Hormone)-based individualized treatment (using a nomogram) with the wide accepted age-based strategy.
- Trial name
- NCT01816789
- Testing
- rFSH, buserelin
- Where
- Italy
- Volunteers
- 194 people
- Sponsor
- Andros Day Surgery Clinic
Infertility
Human Chorionic Gonadotropin Supplementation Prior to In-vitro Fertilization Treatment in Poor Responders
In an era of delayed fertility plans, there is increasing need for fertility treatment in older women with poor response. Human chorionic gonadotropin (hCG) supplementation prior to treatment, as a thecal stimulant, may improve…
- Trial name
- NCT01205009
- Testing
- Ovitrelle
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Infertility
Platelet-Rich Protein and the Endometrium
Platelet-rich plasma (PRP) may promote the endometrial growth and improve pregnancy outcome of patients with thin endometrium undergoing ART treatments.
- Trial name
- NCT02973555
- Testing
- PRP injection
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Infertility, Male
Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples
The purpose of this research study is to evaluate if special types of cells called round spermatids can be gathered from men with non-obstructive azoospermia and used (in absence of elongated spermatids and spermatozoa) to…
- Trial name
- ROSI (NCT04298255)
- Testing
- Round Spermatid Injection (ROSI), Half ROSI-half Sperm Donor Fertilization
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Infertility, Decreased Ovarian Reserve
A Trial of Dehydroepiandrosterone (DHEA) Treatment for in Vitro Fertilization (IVF)
Our long term goal is to elucidate the role of DHEA on follicular dynamics in the human ovary and to better understand the interaction of DHEA supplementation with other treatments for ovulation induction, especially among older…
- Trial name
- NCT00419913
- Testing
- Dehydroepiandrosterone
- Where
- 2 sites in United States, Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Infertility, COVID
Detection of SARS-CoV-2 in Follicular Fluid and Cumulus-oocyte-complexes in COVID-19 Patients
Recently, the world was shaken awake by a pandemic caused by a novel coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2).
- Conditions
- Infertility, COVID, IVF
- Trial name
- COVID_OFF (NCT04425317)
- Testing
- Blood sample
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- CRG UZ Brussel