Clinical trials: IVF Treatment
Diminished Ovarian Reserve (DOR)
Testing Herbal Pretreatment For IVF Success In Women With Low Ovarian Reserve
The goal of this clinical trial is to learn if a traditional Chinese herbal pretreatment can improve pregnancy outcomes in infertile women with diminished ovarian reserve (DOR) who are undergoing in vitro fertilization (IVF) or…
- Trial name
- PRIME (NCT07347340)
- Testing
- Bushen Tongzhi Formula
- Where
- China
- Volunteers
- 348 people
- Sponsor
- Peking Union Medical College Hospital
Infertility, Obesity
Physical Activity and ARTs
Obese women experience increased infertility rate and longer time to conception showing lower pregnancy and live-birth rates both in natural and assisted conceptions.
- Conditions
- Infertility, Obesity, Stable BMI
- Trial name
- SETART (NCT01892111)
- Testing
- Structured exercise program.
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Modena and Reggio Emilia
Poor Response to Ovulation Induction, PCOS
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment
According the World Health Organization (WHO), infertility is a disease of the male or female reproductive system defined by the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse.
- Conditions
- Poor Response to Ovulation Induction, PCOS, Endometriosis, Infertility, Female
- Trial name
- NCT05298657
- Where
- United Arab Emirates
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatima College of Health Sciences
Fertility Disorders, Infertility (IVF Patients)
The Effect of Mindfulness-Based Lifestyle Support Program on Infertile Women
This randomized controlled trial aimed to determine whether a mindfulness-based lifestyle support program would improve quality of life, lifestyle, mindfulness, attention and meditation level and treatment outcomes in women…
- Trial name
- NCT06799507
- Testing
- Interventions Based on Mindfulness, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Sperm Quality, Oligoasthenospermia
Effect of Treatment With Myo-inositol on Human Semen Parameters in Patients Undergoing In Vitro Fertilization Cycles
Myo-Inositol (MI) is a precursors for the synthesis of phosphatidylinositol polyphosphates (PIPs). In male reproduction, it was shown that MI concentration in the seminiferous tubules is higher than in serum and it was increasing…
- Trial name
- NCT01560065
- Testing
- myo-inositol + folic acid
- Where
- Italy
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Infertility
Comparison of IVF and ICSI in Human IVF
In this prospective randomized clinical trial we plan to compare two fertilization method which are widely used during in vitro fertilization (IVF) treatment.
- Trial name
- NCT03513913
- Testing
- ICSI
- Where
- Hungary
- Volunteers
- 600 people
- Sponsor
- Semmelweis University
Infertility
Double ABCX Theory Based Cognitive Psychotherapy Combined Progressive Muscle Relaxation Intervention on Women Undergoing IVF-ET
The in vitro fertilization and embryo transfer(IVF-ET) is a therapy to help the infertile couples. The mental health status of couple under IVF-ET, commonly seen in depression and anxiety, is found to be closely related to the…
- Trial name
- NCT03931187
- Testing
- Cognitive progressive muscular relaxation therapy
- Where
- China
- Volunteers
- 67 people
- Sponsor
- Central South University
Infertility
The Influence of Estradiol Supplementation During the Luteal in Patients Undergoing IVF Treatment
To evaluate whether treatment with Estradiol supplementation during the luteal phase improves IVF outcomes Patients undergoing IVF treatment with controlled ovarian hyperstimulation using a GnRH analog will receive 4 mg estradiol…
- Trial name
- NCT00490308
- Testing
- Treatment with estradiol valerate
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Efficacy of DHEA, Pregnancy Rate
Administration of DHEA in Patients With Poor Response to Ovarian Stimulation for IVF
Poor responders to ovarian stimulation represents one of the most frustrating problems in reproductive medicine. The investigators hypothesize that ovarian response of those patients could improve by treating these patients with…
- Conditions
- Efficacy of DHEA, Pregnancy Rate, Diminished Ovarian Reserve, Changes in AMH
- Trial name
- DHEA (NCT02099916)
- Testing
- gonadotropins plus DHEA, Gonadotropins
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Athens
Adenomyosis, Infertility
Adenomyosis and Pregnancy Outcomes in Women Undergoing Assisted Reproductive Technology Treatment
Rationale: A rising number of adenomyosis cases are being diagnosed in women in the age group of 30 to 40 years. This is due to a combination of better diagnostic imaging techniques and a higher number of women delaying the…
- Conditions
- Adenomyosis, Infertility, ART, Pregnancy Loss
- Trial name
- AdAPT-ART (NCT05418140)
- Testing
- Ultrasound diagnosis of adenomyosis
- Where
- 9 sites in United Kingdom
- Volunteers
- 828 people
- Sponsor
- CARE Fertility UK
Infertility
Individualization of Ovarian Stimulation Using AMH Maximizes the Benefits and Minimizes Complications and Risks
The purpose oh the study is to determine the usefulness of anti-Mullerian hormone (AMH) to identify women at risk of excessive and poor response in controlled ovarian stimulation (COS) for in vitro fertilization (IVF), and the…
- Trial name
- NCT01887652
- Testing
- conventional ovarian stimulation, individualized ovarian stimulation
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- ANDROFERT - Clinica de Andrologia e Reproducao Humana
Infertility
Efficacy and Safety of FSH-GEX™ in Comparison With 150 IU Gonal-f®
The aim of the current study was the determination of the recommended standard treatment dose of FSH-GEX(TM) in women undergoing intracytoplasmic sperm injection (ICSI) treatment as assessed by follicle growth.
- Trial name
- NCT01794208
- Testing
- Follitropin Epsilon, Follitropin Alfa
- Where
- 8 sites in Germany, Hungary
- Volunteers
- 267 people
- Sponsor
- Glycotope GmbH
Female Infertility, Reproductive Disorders
Effect of Comprehensive Spa Rehabilitation on Female Infertility: A Clinical Study in Adult Women (Infertility-Spa)
This is a prospective, single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa treatment (Komplexní lázeňská léčebně rehabilitační péče, KLP) on female infertility at spa facility in Františkovy…
- Conditions
- Female Infertility, Reproductive Disorders, Recurrent Pregnancy Loss
- Trial name
- NCT07542600
- Testing
- Comrehensive Spa Treatment (KLP)
- Where
- Czechia
- Volunteers
- 55 people
- Sponsor
- Institute of Spa and Balneology, public research institution
IVF-ET, Hydrosalpinx
Comparing Radiological Tubal Blockage Versus Laparoscopic Salpingectomy in Infertile Women With Hydrosalpinx During in Vitro Fertilization Treatment
Hydrosalpinx (HX) has a detrimental effect on the rates of implantation, pregnancy, live delivery, and early pregnancy loss during in vitro fertilization (IVF).
- Trial name
- NCT03521128
- Testing
- radiological tubal blockage, laparoscopic salpingectomy
- Where
- China
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Endometriosis, Rectum, Endometriosis of Colon
The (Cost-)Effectiveness of Surgical Excision of Colorectal Endometriosis Compared to ART Treatment Trajectory
To goal of this study is to determine whether laparoscopic resection of colorectal endometriosis results in an increased cumulative live birth rate (CLBR) both spontaneous and after ART (including in vitro fertilization (IVF) or…
- Conditions
- Endometriosis, Rectum, Endometriosis of Colon, Subfertility, Female
- Trial name
- TOSCA (NCT05677269)
- Testing
- Laparoscopic excision of endometriosis, including colorectal endometriosis, In vitro fertilisation or intracytoplasmic sperm injection
- Where
- 10 sites in Netherlands
- Volunteers
- 339 people
- Sponsor
- Leiden University Medical Center
Failure After Assisted Reproductive Technology
Observing the Curative Effect of Assisted Reproduction by TCM Multi-channel Interventional Therapy
Objective: To evaluate the curative effect of TCM multi-channel interventional therapy on women with ART Failure; to compare the curative effect of the dual therapy and triple therapy on women with ART Failure; to choose the best…
- Trial name
- NCT02303665
- Testing
- The dual therapy, The triple therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Infertility
Registry Study of Traditional Morphology Grading Combined With Eeva in IVF Treatment
The purpose of this study is to record and evaluate the use of traditional morphology grading combined with Eeva in the treatment of in vitro fertilization.
- Trial name
- MERGE (NCT01816802)
- Testing
- In-vitro fertilization using Eeva
- Where
- 12 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- Progyny, Inc.
Infertility
The Presence of Microbes in the Sperm and Their Impact on Sperm Capacitation and IVF Treatment
Study Goals: 1. Finding the prevalence of bacteria of the sperm in an innovative and more accurate methode 2. Understanding the effect of microbes on the process of capacitation 3.
- Trial name
- NCT02585297
- Testing
- no intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Pregnancy
Once Daily vs Twice Daily Administration of Gonadotropins in Assisted Reproductive Technologies (ART)
This is a prospective randomized study evaluating dosing frequency of gonadotropin administration in ART cycles.
- Trial name
- QD vs BID (NCT00740025)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Virginia Center for Reproductive Medicine
Female Infertility Due to Diminished Ovarian Reserve
IVF/ICSI Protocols in Poor Responders With Growth Hormone
in this study, we are trying to monitor the effect of the addition of growth hormone on the different down regulation protocols ( long, short, antagonist and microflare).
- Trial name
- NCT01897324
- Testing
- Growth hormone (Norditropin, Novo nordisk)
- Where
- Egypt
- Volunteers
- 287 people
- Sponsor
- Woman's Health University Hospital, Egypt