Clinical trials: IVF Treatment
Infertility
Testosterone Gel in Poor Responders Undergoing IVF
The main purpose of this study is to compare the number of oocytes retrieved after using transdermal testosterone gel 10 mg per day or Dehydroepiandrosterone (DHEA) 75mg per day for 6-8 weeks as pre-treatment for poor ovarian…
- Trial name
- NCT02549690
- Testing
- Testosterone gel, DHEA
- Where
- Vietnam
- Sponsor
- Vietnam National University
Infertility, Female, Web
Responsive Web-based Roadmap (InT-mAp) in Infertility Treatment
Infertility affects approximately 48 million couples and 186 million individuals globally, and it has biological, psychosocial, and economic problems in couples.
- Conditions
- Infertility, Female, Web, Anxiety, IVF
- Trial name
- InT-mAp (NCT05890625)
- Testing
- On going treatment, InT-mAp
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Reproductive Medicine
Evaluate the Interest of the Pre-conceptional Endometrial Immune Profiling to Increase Birth Rates
A prospective, randomized, controlled, open two-arm study to evaluate the interest of the pre-conceptional endometrial immune profiling to increase birth rates.
- Trial name
- PRECONCEPTIO (NCT02262117)
- Testing
- standard care, specific treatment
- Where
- France
- Volunteers
- 493 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Effect of Addition of Aromatase Inhibitor to Ovarian Stimulation Therapy in IVF Treatment
This project seeks to determine whether estradiol suppression achieved with adjuvant treatment with an aromatase inhibitor improves end-follicular and midluteal phase parameters during IVF.
- Trial name
- RIOT-A (NCT02946684)
- Testing
- Letrozole
- Where
- 4 sites in Denmark
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Sven O. Skouby
Controlled Ovarian Stimulation
A Trial to Investigate the Efficacy and Safety of FE 999302 as add-on Treatment to Follitropin Delta (REKOVELLE) in Women Undergoing Controlled Ovarian Stimulation.
The purpose of this phase 2 dose-ranging trial is to investigate the effects of FE 999302 on parameters influencing pregnancy rates in women undergoing Controlled Ovarian Stimulation (COS) with follitropin delta in a long…
- Trial name
- RAINBOW (NCT03564509)
- Testing
- FE 999302 (1 μg) and follitropin delta, FE 999302 (2 μg) and follitropin delta, FE 999302 (4 μg) and follitropin delta
- Where
- 20 sites in Belgium, Czechia and 3 more
- Volunteers
- 620 people
- Sponsor
- Ferring Pharmaceuticals
Fibroid; Uterus Tumor, Complicating Pregnancy, Infertility, Female
Esmya Versus Surgery Before IVF/ICSI
Studying the possible outcome differences between surgery or medical treatment with ulipristalacetate (UPA) solely before 'in-vitro fertilisation/intracytoplasmic sperm injection' (IVF/ICSI) treatment in infertile couples.
- Conditions
- Fibroid; Uterus Tumor, Complicating Pregnancy, Infertility, Female, Surgical Procedure, Unspecified
- Trial name
- NCT04028986
- Testing
- Ulipristal Acetate 5 MG Oral Tablet
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Couple Sterility
Effect of Myoinositol Treatment of Spermatozoa on in Vitro Fertilization Outcome
In the present trial, the investigators aim to evaluate whether semen myo-inositol (MI) treatment is able to improve IVF outcomes.
- Trial name
- MI_ICSI (NCT02050672)
- Testing
- Myo-inositol, untreated
- Where
- Italy
- Volunteers
- 249 people
- Sponsor
- AGUNCO Obstetrics and Gynecology Centre
Pregnancy, Thrombophilia
The Effect of Heparin in Treatment IVF-ET Failure
Embryo transfer failure is defined as ≥3 IVF-embryo transfer failures without pregnancy . In spite of transfer of 3 good quality embryos , just 20-30% of women undergoing IVF will achieve ongoing pregnancy .
- Trial name
- NCT01214772
- Testing
- heparin
- Where
- Iran
- Volunteers
- 86 people
- Sponsor
- Yazd Medical University
Infertility
A Study to Assess if Scratching the Lining of the Womb Prior to IVF Treatment Increases the Chances of Pregnancy
This study aims to see if taking a small sample from the lining of the womb (the 'scratch') before starting in vitro fertilization (IVF) treatment can influence the chance of getting pregnant and having a healthy, term baby.
- Trial name
- NCT01882842
- Testing
- Endometrial biopsy, Transvaginal ultrasound
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Subfertility
BAP-EB as a Predictive Tool for Endometrial Receptivity and Pregnancy Outcome of IVF Treatment
To determine the predictive value of attachment rate of human embryonic stem cells (hESC)-derived trophoblast spheroids (BAP-EB, embryo surrogate) onto endometrial epithelial cells (EEC) on success of IVF treatment and to use the…
- Trial name
- NCT02713854
- Testing
- endometrial biopsy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Subfertility
Mild Versus Conventional Ovarian Stimulation Treatment for In Vitro Fertilization
In vitro fertilization (IVF) is an assisted reproductive technique to achieve pregnancy in subfertile couples of which the average success rate is only 25%.
- Trial name
- FOLFO (NCT00985062)
- Testing
- Mild Ovarian Stimulation Treatment, Conventional Ovarian Stimulation Treatment
- Where
- Netherlands
- Volunteers
- 54 people
- Sponsor
- Erasmus Medical Center
Pregnancy Rate, Implantation Rate
Intrauterine Injection of HCG and Implantation Rate
The study aims to examine the effect of intrauterine injection of HCG on pregnany rate in women undergoing IVF treatment.
- Trial name
- NCT01933126
- Testing
- HCG injection
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Infertility
Adjuvant Growth Therapy in in Vitro Fertilization
In an In Vitro Fertilization (IVF) cycle super ovulating drugs (gonadotropins) are usually taken to stimulate the ovaries to produce more than one egg.
- Trial name
- NCT01715324
- Testing
- Adjuvant Growth Hormon
- Where
- Canada
- Volunteers
- 288 people
- Sponsor
- Clinique Ovo
Infertility, PCOS
Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
Metformin should be administered with caution and could be potentially dangerous in infertile patients with PCOS who show a poor ovarian response and are undergoing gonadotropin-based ovarian stimulation.
- Conditions
- Infertility, PCOS, Prognosis for Poor Response
- Trial name
- NCT01208740
- Testing
- Metformin
- Where
- Italy
- Volunteers
- 88 people
- Sponsor
- University Magna Graecia
Infertility, Female
Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)
This trial investigates the effects of FE 999049 compared to placebo.
- Trial name
- RITA-2 (NCT03738618)
- Testing
- Follitropin delta
- Where
- 24 sites in United States
- Volunteers
- 588 people
- Sponsor
- Ferring Pharmaceuticals
In Vitro Fertilization
Methylprednisolone Addition in IVF Treatment of Infertile Couples
Hypothesis to be tested is whether follicular addition of Methylprednisolone can efficiently control late follicular progesterone rise during IVF treatment
- Trial name
- NCT01220791
- Testing
- In vitro fertilization treatment for infertility
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Universitair Ziekenhuis Brussel
Endometriosis
IVF Versus Surgery for Endometriosis Related Infertility
The management of endometriosis-related infertility remains controversial. In particular, there is an equipoise for infertile women with endometriotic lesions detected at ultrasound.
- Trial name
- SVIDOE (NCT04743167)
- Testing
- Surgery, IVF
- Where
- 3 sites in Italy
- Volunteers
- 206 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Infertility
Involuntary Childlessness and Stress Management
Many couples experience involuntary childlessness and seek treatment at fertility clinics. Going through treatment procedures can be very challenging, time consuming and emotionally demanding.
- Trial name
- NCT01187095
- Testing
- Expressive writing, Active ctrl
- Where
- Denmark
- Volunteers
- 298 people
- Sponsor
- University of Aarhus
Infertility
Anti-Mullerian Hormone (AMH) Versus Antral Follicle Count (AFC) Guided rFSH Dosing Study
The overall objectives of this trial are to: To explore the efficacy and safety of using either antral follicle count (AFC) or anti-Mullerian hormone (AMH) to guide the starting dose of GONAL-f® in ovarian stimulation for…
- Trial name
- NCT01783301
- Testing
- FSH
- Where
- Vietnam
- Volunteers
- 348 people
- Sponsor
- Vietnam National University
Infertility, Endometriosis
Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis
A Phase 3 clinical trial of oral GnRH antagonist pre-treatment for women with endometriosis who are undergoing IVF, with a primary outcome of live birth rate.
- Trial name
- PREGnant (NCT04173169)
- Testing
- Elagolix 200 MG
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- Yale University