Clinical trials: IVF Treatment
Pregnancy, Thrombophilia
The Effect of Heparin in Treatment IVF-ET Failure
Embryo transfer failure is defined as ≥3 IVF-embryo transfer failures without pregnancy . In spite of transfer of 3 good quality embryos , just 20-30% of women undergoing IVF will achieve ongoing pregnancy .
- Trial name
- NCT01214772
- Testing
- heparin
- Where
- Iran
- Volunteers
- 86 people
- Sponsor
- Yazd Medical University
Subfertility, Infertility
Hysteroscopy Before in Vitro Fertilization - Does it Improve the Outcome?
By randomizing sub-fertile women to either control or office-hysteroscopy in the circle prior to IVF or ICSI (intracytoplasmatic sperm injection ) treatment, we aim to enlighten whether hysteroscopy with endometrial biopsy…
- Trial name
- NCT01743391
- Testing
- Office-hysteroscopy with biopsy
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Female İnfertility
Mobile Health Support Before Oocyte Pick-Up in Infertile Women
This study aims to evaluate the effect of the OPUCARE system, a structured mobile health application used before oocyte pick-up (OPU), on medication adherence and quality of life in infertile women.
- Trial name
- OPUCARE (NCT07690969)
- Testing
- OPUCARE, Routine clinical care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Infertility
The Effect of Interactive Music Therapy Applied for Women During the Perioperative Period for IVF on Their Stress Levels
The purpose of this study is to investigate the effect of music therapy on stress levels in female patients applying for in vitro fertilization.
- Trial name
- IVF (NCT06117202)
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Uludag University
Clinical Pregnancy Rate
Effect of Shorten Gonadotropin-releasing Hormone Agonist Therapy on the Outcome of in Vitro Fertilization-Embryo Transfer in Patients With Endometriosis
Gonadotropin-releasing hormone analogue (GnRH-a) is a synthetic decapeptide compound which can down-regulate pituitary function causing a temporary low estrogen state.
- Trial name
- NCT03006406
- Testing
- Long term GnRH-a (3.75mg)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Infertility
GnRH Agonist Administration in the Luteal Phase of ICSI-ET Cycles
A single dose GnRH agonist administration in the luteal phase of assisted reproduction cycles was reported to increase pregnancy and birth rates. This study was done to evaluate the reproducibility of previous findings.
- Trial name
- NCT00516490
- Testing
- triptorelin acetate, Na Cl %0.9
- Where
- Turkey (Türkiye)
- Volunteers
- 570 people
- Sponsor
- V.K.V. American Hospital, Istanbul
Habitual Abortion, Recurrent Pregnancy Loss
Intravenous Immunoglobulin and Prednisolone for RPL After ART.
Recurrent pregnancy loss (RPL) affects around 5 % of women in reproductive age. The underlying cause of RPL is most often unknown, probably multifactorial, and no treatment with documented effect on chance of live birth exists.
- Conditions
- Habitual Abortion, Recurrent Pregnancy Loss, Fertility Disorders, Miscarriage
- Trial name
- RPL (NCT04701034)
- Testing
- Human Intravenous Immunoglobulins, (Privigen (R), CLS Behring), Prednisolone Tablets, Human Albumin Solution
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Endometriosis, Infertility Assisted Reproductive Technology
First Line Surgery or First Line Fertility Treatment Using Assisted Reproductive Technologies in Patients With Advanced Endometriosis
Endometriosis is a chronic disease affecting approximately 10% of women of reproductive age. It is strongly associated with pelvic pain and infertility.
- Trial name
- EndoSOFT (NCT07240363)
- Testing
- Endometriosis surgery
- Where
- 4 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Infertility
Gamete Treatment to Correct Fertilization Failure
In this proposed research study, the investigators plan to assess the efficacy of gametes' (egg and sperm) treatment on fertilization as well as pre- and post-implantation embryo development.
- Trial name
- NCT01944332
- Testing
- gamete treatment
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Weill Medical College of Cornell University
Pregnancy, In Vitro Fertilization
The Impact of Early Embryos Incubation on Pregnancy Rate in IVF
Frozen- thawed embryos obtained by IVF treatments are transferred to the uterus immediately following thawing or after incubation for additional 24-72 hours. The two methods are routine in IVF laboratories.
- Trial name
- IVF-2010 (NCT01287273)
- Where
- Israel
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Martha Dirnfeld
Infertility
Selection of Embryos by Time-lapse
In order to improve success rate by assisted reproductive techniques new techniques are being developed for selection of the embryo with best chance of implantation, establishement of pregnancy and subsequent delivery.The present…
- Trial name
- NCT01138631
- Testing
- Embryoscope
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- University of Aarhus
In Vitro Fertilization, Assisted Reproductive Techniques
Optimizing IVF Treatment - the Impact of Time-lapse Culture and Preimplantation Factor (PIF) on Embryo Development.
The aims of this study are to evaluate: 1. the possible effect of time-lapse culture from day zero (day of oocyte retrieval) on fertilisation rates and embryo quality in standard IVF. 2.
- Trial name
- NCT02222831
- Testing
- Day 0 denudation and time lapse culture on IVF-oocytes.
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Idiopathic Infertility, Infertility Unexplained
Biological Aging Hallmarks-Guided Integrative TCM and Conventional Medicine in Post-Treatment Unexplained Female Infertility
The goal of this clinical trial is to determine whether telomere profiling and other biological aging hallmarks can help identify underlying mechanisms of persistent infertility in women with post-treatment unexplained…
- Conditions
- Idiopathic Infertility, Infertility Unexplained, Infertility (IVF Patients), Infertility Assisted Reproductive Technology
- Trial name
- TECMI (NCT07404969)
- Testing
- 1. Aging Hallmarks Biomarker Profiling (Telomere-Based), 2. Integrative Botanical and Nutraceutical Intervention, 3. Natural Conception or Assisted Reproductive Technologies
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- BEYOND GENOMiX SA, AG, Ltd
Infertility
Ultrasound Study by Texturization as a Predictor of Pregnancy in Oocyte Donation Programs
This study is focused on analysing the application of ultrasound scanning techniques as new biomarkers in reproductive medicine.
- Trial name
- TEXTUGEST (NCT03507322)
- Testing
- Ultrasound texturization
- Where
- Spain
- Sponsor
- Vida Recoletas Sevilla
Infertility, Hypothalamic Amenorrhea
The Luveris In Vitro Fertilization Trial
The purpose of this study is to develop a new protocol using two different types of fertility drugs that is more similar to the way the hormones act in a normal menstrual cycle (period).
- Conditions
- Infertility, Hypothalamic Amenorrhea, Hyperprolactinemia
- Trial name
- NCT00889512
- Testing
- Luveris fixed dose, Luveris increasing dose
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University Reproductive Associates
Infertility, Female, Thrombophilia
Effect of Prophylatic Use of Enoxaparin in Women Undergoing in Vitro Fertilization Treatment
Retrospective study designed to evaluate outcomes in patients undergoing assisted reproduction. Some of them had thrombophilia, and part of them was treated with enoxaparin, started on the day of embryo transfer, and the other…
- Conditions
- Infertility, Female, Thrombophilia, Fertilization in Vitro
- Trial name
- NCT05225155
- Testing
- Enoxaparin
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Faculdade de Medicina do ABC
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
ReceptIVFity & Immunology in ART
The goal of this clinical non-invasive observational pilot study is to improve the prediction of pregnancy success after In Vitro Fertilisation (IVF)/IVF -Intracytoplasmic Sperm Injection (ICSI) treatment by examining the vaginal…
- Trial name
- R-IMinART (NCT06709976)
- Testing
- Vaginal microbiome swab, Menstrual Blood Collection via Menstrual Cup
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Infertility, Miscarriage
Ism1 Versus EmbryoGen Media for Embryo Culture in Previous Pregnancy Loss Cases
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689428
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Infertility
IVF Clinical Trial of Two Different Treatment Protocols.
The purpose of this study is to compare two different in vitro fertilization (IVF) treatments: conventional IVF protocol and minimal stimulation IVF protocol, in terms of success rates, stress of treatment, drug-related side…
- Trial name
- NCT00799929
- Testing
- in vitro fertilization (IVF/ICSI)
- Where
- United States
- Volunteers
- 564 people
- Sponsor
- New Hope Fertility Center
Infertility
Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
This is a Phase 3, randomized, controlled, single-blind, multicenter, parallel-arm trial to assess the safety and efficacy of Pergoveris® (recombinant human follicle stimulating hormone [r-hFSH]/recombinant human luteinising…
- Trial name
- ESPART (NCT02047227)
- Testing
- Pergoveris®, GONAL-f®, Recombinant human chorionic gonadotrophin (r-hCG)
- Where
- Germany
- Volunteers
- 939 people
- Sponsor
- Merck KGaA, Darmstadt, Germany