Clinical trials: Idiopathic Scoliosis, active
Scoliosis, Spine Deformity
Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis
Idiopathic scoliosis of developmental age (AIS) is the most vertebral deformity in the adolescent population, with a prevalence of 1-3%.
- Conditions
- Scoliosis, Spine Deformity, Adolescent Idiopathic Scoliosis
- Trial name
- BS23 (NCT06396286)
- Testing
- single rod
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Adolescent Idiopathic Scoliosis
Trials of Intelligent Nighttime Brace With Smart Padding to Treat of Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity usually associated with intervertebral rotation that takes place during adolescence.
- Trial name
- NCT05790031
- Testing
- Intelligent Nighttime Brace
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Hong Kong Polytechnic University
Adolescent Idiopathic Scoliosis (AIS)
Investigation of Shoulder Position, Upper Extremity Proprioception, and Function in Adolescents With Idiopathic Scoliosis Using Braces
This study aims to investigate the effects of brace use on shoulder position, upper extremity proprioception, and upper extremity function in adolescents with idiopathic scoliosis.
- Trial name
- NCT06904157
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gözde Yagci (Gür)
Adolescence Idiopathic Scoliosis
Validity and Reliability of the Behavioral Regulation in Exercise Questionnaire-2 (BREQ-2) in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a spinal condition that develops during adolescence and often requires long-term conservative treatment, including scoliosis-specific therapeutic exercises.
- Trial name
- NCT07359781
- Testing
- Questionnaire Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Nigde Omer Halisdemir University
Scoliosis, Quality of Life
Psychometric Properties of the Turkish Version of the Staffordshire Adolescent Idiopathic Scoliosis Questionnaire
Patient-Reported Outcome Measures (PROMs) have gained increasing importance in scoliosis research in recent years. Although widely used instruments such as the Scoliosis Research Society-22 (SRS-22) include domains related to…
- Trial name
- NCT07676019
- Testing
- Turkish Version of the Staffordshire Questionnaire for Adolescent Idiopathic Scoliosis (SQAIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Scoliosis Idiopathic Adolescent, Core Stabilization Exercise
Effectiveness of a Horse Riding Simulator in Adolescents With Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity associated with impaired respiratory muscle strength, balance, postural control, body image, and health-related quality of life.
- Conditions
- Scoliosis Idiopathic Adolescent, Core Stabilization Exercise, Horseback Riding, Postural Balance
- Trial name
- NCT07758712
- Testing
- Horse Riding Simulator, Core Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Idiopathic Adolescent Scoliosis, Idiopathic Juvenile Scoliosis
Minimal Invasive Scoliosis or Open Surgery
Surgical treatment for idiopathic scoliosis usually involves open surgery from the back (posterior approach). This method corrects the curve and stabilizes the spine using screws and rods, followed by a fusion of the treated…
- Trial name
- MISCOS (NCT07203586)
- Testing
- Minimally invasive scoliosis surgery, Traditional open scoliosis surgery group
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Uppsala University
Spinal Fusion, Adolescent Idiopathic Scoliosis
Low Dose Dexmedetomidine as a Postoperative Pain Adjunct
This randomized controlled trial examines whether the addition of a low-dose dexmedetomidine infusion to our current multimodal pain management plan decreases narcotic consumption and reduces side effects in adolescent patients…
- Trial name
- NCT06067893
- Testing
- Dexmedetomidine, Normal Saline
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nichole Doyle
Adolescent Idiopathic Scoliosis (AIS)
Validation of the Clinical Decision Support Systems (CDSS) Developed in the EU Horizon PREPARE Project in the Rehabilitative Treatment of Idiopathic Scoliosis
The study aims to validate both the predictive capacity and the clinical usability of the Clinical Decision Support System (CDSS) developed within the PREPARE project (European Union Grant Agreement 101080288 PREPARE…
- Trial name
- PREPARE (NCT07379593)
- Testing
- CDSS simulation, Focus group - clinicians, Focus group - patients
- Where
- Italy
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
Adolescent Idiopathic Scoliosis (AIS)
Detection of Scoliosis
This study aims to evaluate whether plantar pressure data collected during standing and walking can be used with machine learning to support early detection of scoliosis in young people.
- Trial name
- NCT07581015
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University College, London
Scoliosis Idiopathic, Scoliosis; Adolescence
fNIRS-based Analysis and Evaluation of the Effect of Schroth Rehabilitation on Motor Functions in Adolescent Idiopathic Scoliosis (AIS)
This study investigates the effects of Schroth-based rehabilitation on cortical dynamics, body awareness, and quality of life in individuals with Adolescent Idiopathic Scoliosis (AIS).
- Trial name
- NCT06884150
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Idiopathic Scoliosis
Effect of Bifidobacterium Breve Supplementation on the Onset and Progression of Idiopathic Scoliosis
Researchers hypothesized that Bifidobacterium breve Supplement could reduce the progression rate of idiopathic scoliosis in children and potentially prevent the occurrence of new cases of scoliosis.
- Trial name
- NCT07466511
- Testing
- Bifidobacterium breve, Lifestyle Education
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Opioid Free Anesthesia
Opioid-Free Anesthesia Versus Opioid Based Anesthesia For Adolescent Idiopathic Scoliosis
Opioid-free anesthesia (OFA) is a multimodal analgesic approach designed to eliminate the intraoperative use of systemic, neuraxial, or intracavitary opioids.
- Trial name
- NCT07389096
- Testing
- Dexmedetomidine, Fentanyl (IV)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nashwa Ahmed
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis
Kids With Iron Deficiency and Scoliosis
This study is a randomized controlled trial of preoperative oral iron supplementation, to identify whether iron deficiency is a modifiable risk factor for adverse surgical outcomes such as red blood cell transfusion and…
- Conditions
- Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies
- Trial name
- KIDS (NCT06042699)
- Testing
- Oral ferrous sulfate
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Columbia University
Adolescent Idiopathic Scoliosis
Interest of Adapted Physical Activity by Tele-rehabilitation in Chronic Pathology - Idiopathic Scoliosis in Adolescents
This study is a randomised controlled trial designed to compare two adapted physical activity treatments for adolescent idiopathic scoliosis (AIS).
- Trial name
- NCT06262269
- Testing
- Home-based adapted physical activity program supervised by an APA teacher via individual video conference., First period of the home-based adapted physical activity program with an exercise booklet., Second period of the home-based adapted physical activity program with an exercise booklet.
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Association des Paralysees de France (APF)
Scoliosis
Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis
Scoliosis is a three-dimensional deformity affecting the orientation and position of the spine. Locally, the shape of the vertebra is also affected.
- Trial name
- NCT02434003
- Where
- 9 sites in United States, Canada and 4 more
- Volunteers
- 1,200 people
- Sponsor
- St. Justine's Hospital
Adolescent Idiopathic Scoliosis
Minimally Invasive Surgery vs Standard Posterior Approach in the Treatment of Developmental Idiopathic Scoliosis
This is a randomized trial with 1:1 allocation. The aim of the study is to evaluate clinical and radiographic outcomes in patients with developmental age idiopathic scoliosis treated with mini invasive scoliosis surgery (MIS)…
- Trial name
- NCT05860673
- Testing
- mini invasive scoliosis surgery, posterior spinal fusion technique
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Istituto Ortopedico Rizzoli
Adolescent Idiopathic Scoliosis (AIS), Juvenile Idiopathic Scoliosis
Impact of Spinal Curves on Asymmetric Posture in Idiopathic Scoliosis
Asymmetric postures are often observed in patients with adolescent idiopathic scoliosis (AIS) and are partially associated with instability in sitting and standing positions, as well as with imbalances in gait kinematic…
- Trial name
- ISAPIS (NCT06733623)
- Where
- Italy
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Istituto Scientifico Italiano Colonna Vertebrale
ASD, Scoliosis Idiopathic Adolescent
Quality of Life, Psychosocial Burden, and Structural-functional Status in Adults With Spinal Deformity.
This study examines which factors influence quality of life in adults with a spinal deformity. It looks at imaging findings together with pain, daily functioning, psychosocial factors, and frailty to support more person-centred…
- Conditions
- ASD, Scoliosis Idiopathic Adolescent, Scoliosis Idiopathic Adolescent Treatment
- Trial name
- ASD-QoL (NCT07749534)
- Testing
- first corrective surgery, Reoperation
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Adolescence Idiopathic Scoliosis
Machine Learning Prediction of Disease Progression in Adolescent Idiopathic Scoliosis
Background and Problem Overview Adolescent Idiopathic Scoliosis (AIS) is a progressive musculoskeletal disorder characterized by a three-dimensional deformation of the spine occurring during adolescence.
- Trial name
- NCT07556042
- Testing
- Core Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University