Clinical trials: Ileostomy Closure
Ileostomy - Stoma, Inflammatory Bowel Diseases
Stoma Closure and Reinforcement Trial ll
Hernia formation at sites of ostomy closure is a common complication. The investigator believes that using evidence based hernia repair techniques as a preventive measure during closure of ostomies will reduce the incidence of…
- Trial name
- SCAR-ll (NCT04916067)
- Testing
- Mesh Implantation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Ileostomy; Complications
Stimulation of Efferent Loop Prior to Ileostomy Closure
The aim of this study is to compare postoperative ileus between stimulated and unstimulated patients prior to ileostomy closure.
- Trial name
- NCT01881594
- Testing
- Procedure/Surgery
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Diverticular Disease of Colon, Colostomy - Stoma
ARES Trial: Approach to Resection and Evaluation in Severe Diverticulitis
This observational study was conducted across five surgical centers in Italy, including both academic and community hospitals, from January 2017 to December 2022.
- Conditions
- Diverticular Disease of Colon, Colostomy - Stoma, Loop Ileostomies
- Trial name
- ARES (NCT07094594)
- Where
- Italy
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Incisional Hernia, Ileostomy - Stoma
Effect of Duramesh™ on Hernia Formation After Ileostomy Closure
Diverting ileostomy is frequently utilized to protect high-risk anastomoses, though it is not shown to reduce the leak rate it may reduce the severe consequences of an anastomotic leak.
- Trial name
- NCT06511414
- Testing
- duramesh, Control
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Northwestern University
Rectal Neoplasm
Loop Ileostomy Closure:Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site?
There are severel problems associated with the closing of a temporary loop-ileostomy after surgery for rectal cancer. The purpose of this study is to answer two questions: 1.
- Trial name
- LISTO (NCT02669992)
- Testing
- Stapled or Hand-sewn anastomosis, Mesh or suture stoma site closure
- Where
- 11 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Rectal Cancer
Efficacy of Stimulation of the Efferent Loop and Rehabilitation of the Pelvic Floor in the Quality of Life of Patients Who Underwent Anterior Resection of the Rectum (ENESP): Randomized Clinical Trial
Many of the patients operated with sphincter preservation will present an alteration of bowel function and defecation. This dysfunction is variable in its symptoms and severity, and manifests itself in the form of urgency…
- Trial name
- ENESP (NCT04569331)
- Testing
- Stimulation of efferent loop, Rehabilitation pelvic floor
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Fecal Incontinence, Quality of Life
Value of Anorectal Manometry Before Ileo- or Sigmoidostomy Closure After Rectal Resection
Background: High prevalence of fecal incontinence after rectal resection in patients with rectal carcinoma. Hypothesis: Anorectal manometry done before ileostomy or sigmoidostomy closure can predict fecal incontinence.
- Trial name
- NCT02196597
- Where
- 3 sites in Germany
- Volunteers
- 30 people
- Sponsor
- German Society for Neurogastroenterology and Motility
Incisional Hernia, Surgical Site Infection
Prophylactic Mesh Reinforcement for Stoma Closure
In the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection …
- Conditions
- Incisional Hernia, Surgical Site Infection, Postoperative Pain, Hospital Stay, Length of Stay in Hospital From Surgery to Discharge
- Trial name
- OASIS (NCT06157645)
- Testing
- Prolene mesh
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Ileostomy; Complications
The Protective Role of GABA Stimulation Before Ileostomy Closure
The goal of this clinical trial is to explore whether preoperative stimulation of the distal limb of the ileostomy loop with gamma aminobutyric acid (GABA) could effectively reduce the incidence of complications after ileostomy…
- Trial name
- NCT05905393
- Testing
- preoperative stimulation of the efferent loop with GABA before ileostomy closure surgery, preoperative stimulation of the efferent loop with only physiological saline
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University
Ileostomy - Stoma, Rectal Cancer
Early Ileostomy Closure for Rectal Cancer Patients in North America
Our preliminary work demonstrates that there is buy-in from both patients and surgeons with regards to early ileostomy closure (EIC) for select rectal cancer patients undergoing restorative proctectomy (RP) and diverting loop…
- Trial name
- NCT05027737
- Testing
- Early Ileostomy Closure
- Where
- 4 sites in Canada
- Volunteers
- 118 people
- Sponsor
- Jewish General Hospital
Colonic Neoplasms, Ileostomy - Stoma
Early Closure Versus Conventional Closure in Postoperative Patients With Low Anteriresection for Rectal Cancer
Colorectal cancer worldwide is the third most common in men and the second in female, although mortality is not as high as its incidence, there is less survival in developing countries.
- Conditions
- Colonic Neoplasms, Ileostomy - Stoma, Colorectal Surgery
- Trial name
- NCT03746353
- Testing
- early ileostomy closure
- Where
- 3 sites in Colombia
- Volunteers
- 52 people
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Surgical Site Infection, Wound Heal
The Efficacy of Purse-string Skin Closure With Negative Pressure Wound Therapy (NPWT) After Ileostomy Reversal
Evaluating the effectiveness of the existing 'linear suture + wound drain placement' and 'purse-string suture + negative pressure wound therapy' through a prospective comparative study
- Trial name
- NCT04986111
- Testing
- Linear skin closure with wound drain, Purse-string skin closure with negative pressure wound therapy
- Where
- South Korea
- Volunteers
- 138 people
- Sponsor
- Seoul National University Bundang Hospital
Rectal Cancer
Effectiveness and Safety Study on Different Timing of Preventive Ileostomy Closure After Surgery for Rectal Cancer
The purpose of this study is to evaluate the appropriate timing to do preventive ileostomy closure after total mesorectal excision of rectal cancer.
- Trial name
- NCT02665026
- Testing
- stoma closure at different times
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Huashan Hospital
Rectal Cancer
Closure of Protective Ileostomy 2 vs. 12 Weeks After TME
The purpose of this study is to compare the feasibility, safety, and quality of life (QOL) in patients (pts) undergoing protective ileostomy closure after 2 weeks with a closure after 12 weeks.
- Trial name
- Closure2vs12 (NCT02609451)
- Testing
- Ileostomy closure
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Kantonsspital Liestal
Ileostomy, Colorectal Surgery
Early vs Standard Ileostomy Reversal
This randomized controlled trial compares early (8 weeks) versus standard (12 weeks) ileostomy reversal in patients with confirmed anastomotic healing, evaluating postoperative complications and recovery outcomes.
- Trial name
- NCT07601594
- Testing
- Ileostomy reversal
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Gulab Devi Hospital
Ileostomy - Stoma
Loop Ileostomy Closure as a 23-hour Stay Procedure, a Multi-center Randomized Controlled Trial
The purpose of this study is to assess the safety and feasibility of ileostomy closure performed in a 23 hours hospitalization setting, using a multi-center, open-label, randomized controlled trial comparing patients being…
- Trial name
- ILEO (NCT03941522)
- Testing
- Early discharge from hospital
- Where
- 2 sites in Canada
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Loop Ileostomy Closure
Prophylaxis of Ileostomy Closure Site Hernia by Placing Mesh
Design Prospective , randomized, parallel phase IV. Objectives Main objective Evaluate the effectiveness of the placement of a resorbable mesh in the prevention of incisional hernia of the abdominal wall at the site of a loop…
- Trial name
- ILEOCLOSE (NCT02226887)
- Testing
- MESH, NO MESH, Post-operative Imaging
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Ileostomy - Stoma, Ileostomy; Complications
Stimulation of the Efferent Loop Before Loop Ileostomy Closure
The purpose of the study is to determine the impact of the efferent loop stimulation of a loop ileostomy prior to closure on postoperative complications such as ileus and hospital stay
- Conditions
- Ileostomy - Stoma, Ileostomy; Complications, Stoma Ileostomy, Ileus Paralytic
- Trial name
- NCT03424447
- Testing
- efferent limb stimulation
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital de Basurto
Perianal Dermatitis, Diaper Dermatitis
Perianal Maceration in Pediatric Ostomy Closure Patients
This pilot study will explore whether preoperative application of stool from the stoma bag to the perianal area will prevent/ decrease postoperative perianal maceration in pediatric ostomy closure patients.
- Conditions
- Perianal Dermatitis, Diaper Dermatitis, Postoperative Complications, Colostomy Site
- Trial name
- NCT04606004
- Testing
- Stool application, Standard of care skincare
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Incisional Hernia
Efficacy of an Onlay Mesh for Prevention of Incisional Hernia After Loop Ileostomy Closure
The aim of the present study is to determine the efficacy of the placement of an onlay mesh to prevent incisional hernia after loop ileostomy closure in patients with a prior rectal resection for cancer
- Trial name
- ILEOMESH (NCT02896686)
- Testing
- Control CT, Clinical Follow Up, Reinforcement with Light Polypropylene Mesh
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Joan XXIII de Tarragona.