Clinical trials: Ileus Postoperative
Postoperative Ileus
Effect of TU-100 on Gastrointestinal and Colonic Transit in Humans
The purpose of this study is to compare the dose related effects of orally administered TU-100, a botanical agent that modulates gastrointestinal nerves, on gastrointestinal motility and colonic transit of solids.
- Trial name
- NCT00871325
- Testing
- Daikenchuto (TU-100)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tsumura USA
Postoperative Complications, Constipation
Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects
This is the first multiple-dose experience in humans with MOA-728 in an oral formulation. This study will provide an assessment of the safety, tolerability, and pharmacokinetics (PK) of MOA-728 following administration of…
- Trial name
- NCT00311350
- Testing
- MOA-728
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Bowel Ileus, Flatus
Chewing Gum on Postoperative Ileus in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_1 (NCT03666377)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cesarean Section Complications
Outcomes of Early Versus Delayed Oral Feeding After Cesarean Section in Korle-bu Teaching Hospital
study compares the outcomes of feeding mothers early (4 hours ) after cesarean section compared to delayed feeding (on post operation day 1) in terms of gastrointestinal function and maternal satisfaction with the feeding…
- Trial name
- NCT03070795
- Testing
- early feeding, delayed feeding
- Where
- Ghana
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Postoperative Ileus
The Effect of Gum Chewing on Postoperative Ileus After Gynecologic Surgery
The investigators are randomizing patients to receive chewing gum (Extra Sugar Free, Spearment) every 4 hours during waking hours for 15 minutes versus standard postoperative care.
- Trial name
- GumGyn (NCT01579175)
- Testing
- Chewing gum
- Where
- 2 sites in United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postoperative Ileus
Coffee Consumption for Intestinal Function Recovery After Laparoscopic Gynecologic Surgery
Minimally invasive surgery (MIS) has revolutionized women's healthcare. Laparoscopy is an excellent route of MIS. Today, laparoscopic surgery is one of the major procedure in the management of a gynecologic disease.
- Trial name
- NCT03963180
- Testing
- coffee
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Gum Chewing, Preoperative
Preoperative Chewing Gum on Anxiety and Postoperative Nausea and Vomiting, Gastrointestinal Function
The aim of this study was to investigate the effects of chewing gum before surgery on preoperative anxiety, postoperative gastrointestinal functions (time to first gas, time to first defecation, bowel sounds, abdominal…
- Conditions
- Gum Chewing, Preoperative, Anxiety, Postoperative Nausea and Vomiting
- Trial name
- NCT06603025
- Testing
- chewing gum
- Where
- Cyprus
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Postoperative Ileus
A Study in Healthy Male Subjects Designed to Assess the Mass Balance Recovery and Pharmacokinetics of 14C TZP-101
A study to investigate the mass balance recovery and pharmacokinetics of 14C TZP-101.
- Trial name
- NCT01668199
- Testing
- TZP-101
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Norgine
Acupressure, Post-Op Complication
Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section
Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis…
- Conditions
- Acupressure, Post-Op Complication, Cesarean Section, Bowel Ileus
- Trial name
- NCT04620850
- Testing
- Acupressure
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Colorectal Cancer, Inflammatory Bowel Diseases
Sublingual Microcirculation and Postoperative Ileus
The aim of this pilot study is to establish if a correlation between sub-lingual microcirculation measured by Orthogonal polarization spectral (OPS) imaging and symptoms of postoperative ileus exist in patients undergoing…
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Gastrointestinal Dysfunction
- Trial name
- NCT01828047
- Testing
- orthogonal polarization spectral (OPS) imaging
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Gabriele Baldini, MD, MSc, Assistant Professor
Postoperative Ileus, Cesarean Section Complications
The Effect of Caffeine Ingestion in Prevention of Postoperative Ileus After Caesarean Section.
Many trials have been made to prevent paralytic ileus , including administration of prokinetic drugs , early resumption of feeding, gum chewing and adequate pain control.
- Conditions
- Postoperative Ileus, Cesarean Section Complications, Caffeine
- Trial name
- NCT03815877
- Testing
- Nescafe Gold ® coffee, Nescafe Gold DECAF® coffee
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Ileus
RCT Gum Chewing on Bowel Function After Abdominal Surgery in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_RCT (NCT02261454)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Perforated Duodenal Ulcer
Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal Surgeries
ABSTRACT BACKGROUND: Enhanced recovery after surgery (ERAS) protocols have been widely studied in elective abdominal surgeries and have shown better outcomes.
- Trial name
- NCT04431037
- Testing
- Early oral feeding/Enhanced recovery after surgery protocols
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- College of Physicians and Surgeons Pakistan
Ileus Postoperative, Postoperative Nausea and Vomiting
Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery
The purpose of this research is to determine if gastric point of care ultrasound (G-POCUS) can be used to help clinicians determine when to feed patients or when to insert or remove nasogastric tubes for patients recovering from…
- Trial name
- NCT05796063
- Testing
- gastric point of care ultrasound
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Effects of Coffee Ingestion on Recovery of Bowel Function
>The Purpose of This Study Was to Determine Whether Consuming a 100-mL Cup of Coffee is Effective in Preventing or Reducing Postoperative Ileus After Laparotomy of Benign Gynecological Patients
Comparison of the effectiveness coffee (with or without caffeine) ingestion and water for reducing the duration of Postoperative ileus after Laparotomy of Benign Gynecological Patients
- Trial name
- NCT03660267
- Testing
- caffeine coffee, decaffiene coffee, still water
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Colorectal Cancer
Simo Decoction and Acupuncture on POI in Colorectal Cancer
Colorectal cancer resection is one of the most common types of abdominal surgery. Though most patients undergoing colorectal resection show recovery of bowel movements within a week, some have prolonged intestinal paralysis or…
- Trial name
- SMD/POI (NCT02813278)
- Testing
- simo decoction, gum chewing
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Ileostomy; Complications, Bowel Obstruction
Implementing a Low Fiber Diet vs. Regular Diet in Postoperative Colorectal Patients With Ileostomies
The primary objective of this study is to prospectively evaluate rate of post-operative ileus or obstruction in patients with ileostomies receiving low fiber diet vs. regular diet starting post-operative day 1.
- Conditions
- Ileostomy; Complications, Bowel Obstruction, Postoperative Ileus
- Trial name
- NCT04675606
- Testing
- Regular diet, Low fiber diet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Ileus.
Does Sugared or Sugar Free Chewing Gum Reduces Postoperative Ileus After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is now very common procedure to remove the gall bladder from abdomen. After this procedure many patients suffer from the non functioning of intestine and stomach which is very common after any…
- Trial name
- NCT02162134
- Testing
- sugar free chewing gum, sugared chewing gum, Tab. Midazolam 7.5 mg
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Benazir Bhutto Hospital, Rawalpindi
Complication, Postoperative
Early Initiation of Oral Feeding Versus Traditional Feeding Post Caesarean Section
Early initiation of oral feeding, within 6-12 hours post-caesarean section, has been noticed to be well tolerated by patients and helps them recover fast.
- Trial name
- NCT06539117
- Testing
- Early feeding post caesarean section
- Where
- Nigeria
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Darlington-Peter Chibuzor Ugoji
Paralytic Ileus, Nausea
The Impact of Preoperative Bowel Exercise on Postoperative Bowel Functions in Gynecologic Malignancies
Gastrointestinal dysfunction is a common complication after abdominal gynecologic oncology surgery. There are numerous studies in the literature addressing the management of bowel function in the postoperative period.
- Conditions
- Paralytic Ileus, Nausea, Defecation Disorder
- Trial name
- IPBEPOBF (NCT06113718)
- Testing
- Abdominal Exercise (digital rectal stimulation, abdominal massage)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital