Clinical trials: Ileus Postoperative
Colorectal Disorders, Postoperative Ileus
Does Epidural Anesthesia Reduce Postoperative Ileus Following Colorectal Surgery?
The use of epidural analgesia (EA) has been suggested as an integral part of an enhanced recovery program for colorectal surgery. However, the effects of EA on postoperative ileus remain controversial.
- Trial name
- NCT04429425
- Testing
- epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Ileus
A Study Evaluating Intravenous (IV) MOA-728 for the Treatment of Postoperative Ileus (POI) in Participants After Ventral Hernia Repair
This study will evaluate the safety and efficacy of two different dose regimens (12 milligrams [mg] and 24 mg) of IV MOA-728 versus placebo in shortening the time to return of bowel function in participants receiving opioid…
- Trial name
- NCT00528970
- Testing
- MOA-728
- Where
- 106 sites in United States, Australia and 9 more
- Volunteers
- 374 people
- Sponsor
- Bausch Health Americas, Inc.
Ileus, Neoplasms
Acupuncture to Prevent Postoperative Bowel Paralysis (Paralytic Ileus)
The purpose of this study is to determine if acupuncture is effective in preventing prolonged postoperative paralysis of the gastrointestinal tract among patients undergoing colostomy/ileostomy closure.
- Trial name
- NCT00065234
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Postoperative Ileus
Role of Chewing Gum in Reducing Post Operative Ileus After Reversal of Ileostomy
Postoperative ileus is generally referred to as the transient impairment of bowel motility after abdominal or other surgery and diagnosed by postoperative abdominal pain vomiting constipation and distension.
- Trial name
- NCT02155153
- Testing
- Sugar Free Chewing Gum
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Services Hospital, Lahore
Postoperative Pain, Postoperative Nausea and Vomiting
A Study to Assess Analgesic Efficacy of Intravenous Lignocaine
The primary objectives of this study are to analyse the effect of perioperative systemic infusion of lignocaine on postoperative pain, postoperative nausea and vomiting and perioperative levels of inflammatory mediators in…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Ileus
- Trial name
- NCT01699919
- Testing
- Intravenous lignocaine
- Where
- India
- Volunteers
- 134 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Post Operative Ileus
Alvimopan Use in Polytraumatized Patients
To evaluate the efficacy and safety of Alvimopan(12 mg) in recovery of bowel function in an emergency trauma setting without the pre-operative dosage in patients that will receive abdominal surgery.
- Trial name
- NCT03068975
- Testing
- Alvimopan
- Where
- Puerto Rico
- Volunteers
- 3 people
- Sponsor
- University of Puerto Rico
Postoperative Ileus
Simple Bed Exercises for Reducing Postoperative Ileus in Colorectal Surgical Patients.
The purpose of this study is to examine the effect of simple bed exercises for reducing postoperative ileus among colorectal surgical patients who have completed colorectal surgery and are experiencing postoperative ileus.
- Trial name
- NCT07014046
- Testing
- Simple bed exercises
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Postoperative Ileus.
Does Sugared or Sugar Free Chewing Gum Reduces Postoperative Ileus After Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy is now very common procedure to remove the gall bladder from abdomen. After this procedure many patients suffer from the non functioning of intestine and stomach which is very common after any…
- Trial name
- NCT02162134
- Testing
- sugar free chewing gum, sugared chewing gum, Tab. Midazolam 7.5 mg
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Benazir Bhutto Hospital, Rawalpindi
Post-operative Ileus
Nicotine Gum Recovery After Colorectal Surgery
The purpose of this study is to evaluate whether the use of nicotine gum in the postoperative period influences surgical outcome in patients undergoing colorectal surgery.
- Trial name
- NCT01662115
- Testing
- Nicotine gum, Regular chewing gum
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The Cleveland Clinic
Ileus
Effect of Acupuncture on Postoperative Ileus After Gastric Surgery (EAPIG)
Postoperative ileus (POI) is a common problem after major abdominal surgery. Acupuncture is being accepted in the West as a treatment option for managing POI and various functional gastrointestinal disorders.
- Trial name
- EAPIG (NCT02480361)
- Testing
- acupuncture
- Volunteers
- 10 people
- Sponsor
- Daegu Catholic University Medical Center
Hysterectomy, Gastrointestinal Motility Disorder
Coffee Consumption After Laparoscopic Hysterectomy
Postoperative ileus and delayed bowel recovery remain common concerns following laparoscopic hysterectomy despite enhanced recovery protocols.
- Conditions
- Hysterectomy, Gastrointestinal Motility Disorder, Postoperative Ileus
- Trial name
- COFFEE-LH (NCT07686510)
- Testing
- Postoperative Coffee Consumption
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul Medipol University Hospital
Postoperative Ileus
Intravenous (IV) Methylnaltrexone (MNTX) in the Prevention of Post-Operative Ileus
A double-blind, randomized, parallel-group study designed to evaluate the safety and activity of IV MNTX in the treatment of Post-Operative Ileus (POI) in patients who underwent segmental colectomies via laparotomy.
- Trial name
- NCT01367548
- Testing
- IV Methylnaltrexone (MNTX)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Bausch Health Americas, Inc.
Ileus
Acupuncture and Post-Operative Ileus
Postoperative ileus, the transient cessation of normal bowel function, is a universal aspect of colon surgery. Its occurrence may lead to increased patient discomfort and additional time and cost to hospital stay.
- Trial name
- NCT00655317
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- Mayo Clinic
Short Bowel Syndrome
Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients
This study will determine if air-displacement plethysmography (ADP) provides accurate measurement of body composition (percent body fat and fat-free mass) in pediatric patients with intestinal failure, as compared to body…
- Trial name
- NCT02561819
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Christopher Duggan
Postoperative Ileus
Effect of Sugared Chewing Gum on Gastrointestinal Recovery After Major Colorectal Surgery
The Purpose of this study is to evaluate the effect of gum chewing on recovery of gastrointestinal function in patient undergoing major colorectal surgery.
- Trial name
- NCT01559662
- Testing
- Sugared Chewing Gum (Juicy Fruit)
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Cedars-Sinai Medical Center
Rectal Cancer Surgery, Middle and Low Rectal Cancer
Pelvic Floor Peritoneal Closure to Prevent Postoperative Ileus in Mid-Low Rectal Cancer Surgery
The goal of this clinical trial is to determine whether closing the pelvic floor peritoneum during laparoscopic radical resection of mid-low rectal cancer can reduce the incidence of postoperative ileus.
- Conditions
- Rectal Cancer Surgery, Middle and Low Rectal Cancer, Intestinal Obstruction, Ileus
- Trial name
- TOWER-1 (NCT07432542)
- Testing
- Pelvic floor peritoneum reconstruction
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Sun Yat-sen University
Colonic Cancer
Abdominal Massage After Colon Surgery for Cancer
Postoperative ileus is a transient gastrointestinal dysmotility following abdominal surgery that leads to bloating, abdominal distention, visceral pain, nausea, vomiting, and delayed passage of flatus and stool.
- Trial name
- MATRAC_Ter (NCT07713472)
- Testing
- ABDOMINAL MASSAGE, Usual physiotherapeutic intervention
- Where
- France
- Volunteers
- 225 people
- Sponsor
- University Hospital, Grenoble
Ileus Postoperative
Preventing Gastrointestinal Disturbance in Patients After Longitudinal Laparotomy.
This is a multi-center, randomized, double blind, placebo-controlled, phase 2 pilot efficacy study.
- Trial name
- ORE001PIIPOI (NCT05923086)
- Testing
- ORE001
- Where
- 3 sites in Germany
- Volunteers
- 126 people
- Sponsor
- Orexa BV
Postoperative Ileus
Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection?
The purpose of this study is to determine if consuming an 8 ounce cup of coffee with breakfast and lunch is effective in preventing or reducing postoperative ileus.
- Trial name
- NCT01130675
- Testing
- caffeinated coffee
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Massachusetts, Worcester
Post Operative Bowel Dysfunction
Study Evaluating IV Methylnaltrexone for the Treatment of Post Operative Ileus
Primary Objective: In subjects who have undergone segmental colectomy, the time between the end of surgery and first bowel movement is significantly shorter with the investigational MOA-728 regimen than with a placebo regimen.
- Trial name
- NCT00387309
- Testing
- Methylnaltrexone (MOA-728)
- Where
- 92 sites in United States, Australia and 8 more
- Volunteers
- 495 people
- Sponsor
- Bausch Health Americas, Inc.